Immunology Test

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Immunology Test

1 / 60

Which cell is T helper:

a. CD4

b. CD15

c. CD8

d. CD14

2 / 60

The initial complement component that is bound by complement-fixing antibodies is:

a. C5a

b. C3b

c. C1s

d. C1q

3 / 60

The answer below is/are artificial active immunization?:

a. Attenuated organisms

b. Killed organisms and Attenuated organisms

c. Exposure to the infections

d. Killed organisms

4 / 60

The following molecules can activate B cells to secrete antibody, EXCEPT:

a. Hapten

b. Antigenic determinant

c. Allergen

d. Antigen

5 / 60

Hyper variability regions are present in:

a. Heavy chain only

b. Dark chain

c. Heavy and light

d. Light chain only

6 / 60

Which of the following immune cells/molecules are most effective to destroying intracellular
pthogens ?:

a. B cells

b. T cytotoxic cells

c. Plasma cells

d. T helper cells

7 / 60

Which of the following statements about leukocyte function is false?:

a. Neutrophils phagocytose pathogens .

b. Leukocytes are cells of the immune response.

c. Eosinophils kill parasites

d. Eosinophils release histamine .

8 / 60

All of the following are the type RNA virus, EXCEPT?:

a. Hepatitis C

b. Hepatitis A

c. Hepatitis B

d. Hepatitis E

9 / 60

In chronic infection of hepatitis B, the antibody persists in the whole life is?:

a. HBsAb

b. HBsAg

c. HBcAb

d. HBcAg

10 / 60

The Natural Killer T Cells work in the immune system :

a. Adaptive immunity

b. Adaptive immunity and Innate immunity

c. Innate immunity

d. Link between Adaptive and Innate immune

11 / 60

Which of the following statement is related to IgG physiology in humans?:

a. It is confined to the bloodstream, giving the host protection against blood-borne pathogens.

b. Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.

c. It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.

d. IgG crosses the placental barrier, and thereby provides passive immunity to the fetus.

12 / 60

The TH cells produced cytokines to response the viral infection?:

a. Interferon

b. IL-2

c. Chimokine

d. Tumor necrose factor

13 / 60

The function of LGL cell is:

a. Respose to tumor cells

b. Response to antibody

c. Kill pathogen

d. Response to bacteria infection

14 / 60

The CD marker of B cells are?:

a. CD16 and CD56

b. CD19 and CD21

c. CD3 and CD8

d. CD3 and CD54

15 / 60

Which among the following is anti-bacterial ?:

a. Hormone

b. Protein

c. Lysozyme

d. Interferon

16 / 60

The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBsAg

b. HBcAb

c. HBcAg

d. HBsAb

17 / 60

Myeloid cells below lived in tissue:

a. Basophil

b. Neutrophil

c. Macrophage

d. Lymphocyte

18 / 60

The first immunoglobulin secreted by B cells to make up memory cells is?:

a. IgA

b. IgM

c. IgD

d. IgG

19 / 60

B Cells are activated by?:

a. Antibody

b. Memory cells

c. Interferon

d. Antigen

20 / 60

The average incubation period of Hepatitis A is?:

a. 15 days

b. 60 days

c. 30 days

d. 7 days

21 / 60

Clinical abnormalities of the Immune system can result from the activities below:

a. T cell secrete cytokine

b. Plasma cells secrete antibody

c. Neutrophils kill bacteria

d. Abnormal lymphocyte proliferation

22 / 60

Which cell is directly secreted immunoglobulin:

a. T lymphocyte

b. B lymphocyte

c. Plasma cell

d. Macrophage

23 / 60

Variable regions of immunoglobulin are:

a. Able to fix complement

b. C-terminal of heavy chains

c. N-terminal of heavy chains

d. Specific recognition of antigen

24 / 60

Individuals unable to make the C4b would be expected to have frequent infections of the :

a. Thalassemia

b. Diabetis

c. Liver disease

d. Bacteria

25 / 60

Which of the following immune cells are effective to destroying intracellular pathogens:

a. Antibodies

b. T helper cells

c. B cells

d. T cytolytic cells

26 / 60

The following antigen activate 25% of T cells:

a. HIV

b. Mycose

c. Staphylococus toxin

d. Virus

27 / 60

Skin is a________ barrier:

a. Physiological

b. Inflammatory

c. Phagocytic

d. Anatomical

28 / 60

The immunoglobulin class which is the least abundant in the normal adult is :

a. IgG

b. IgD

c. IgE

d. IgA

29 / 60

The following vaccines is not used in United State?:

a. Polio

b. Hepatitis A

c. Varicella

d. Tuberculsis

30 / 60

In the complement system, the lytic pathway initiated by the complement :

a. C1qrs

b. C4

c. C5

d. MBL

31 / 60

The incubation period of HBV in the body is?:

a. 30-60 days

b. 30-90 days

c. 60-100 days

d. 45-180 days

32 / 60

The following statement is true for helper T-cells :

a. Cytotoxic cells recognize antigen with MHC class II

b. Helper cells recognize antigen with MHC class I and II

c. Helper cells recognize antigen with MHC class II

d. Helper cells recognize antigen with MHC class I

33 / 60

The followings statement are TRUE for Target cell lysis and destruction,EXCEPT :

a. Complement binding to IgG and IgM which have bound to epitopes on the target cell

b. Perforin released from antigen-specific cytotoxic T-cells

c. Complement binding to IgE antibodies which have bound to epitopes on the cell surface

d. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

34 / 60

The Biological Effects of C3b is :

a. Phagocyte activation

b. Anaphylaxia

c. Lack of opsonisation

d. Susceptibility to bacterial infections

35 / 60

The following answer is NOT true for interleukins?:

a. Regulation between cells

b. They are not in stock

c. Produced by T cells

d. Produced by antigen

36 / 60

Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:

a. Halitosis

b. Phagocytosis

c. Chemotaxis

d. Botulism

37 / 60

Superantigens presented to T cells by :

a. B cell

b. Monocyte

c. APC

d. Mast cell

38 / 60

The functional activity of the T-cell:

a. Occurs after recognition of an epitope

b. Is related with CD4 or CD8 associated polypeptides, Occurs after recognition of an epitope, Can be mediated through cytokines

c. Is related with CD4 or CD8 associated polypeptides

d. Can be mediated through cytokines

39 / 60

Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Pertussis

b. Hepatitis B

c. Polio

d. Rabies

40 / 60

IgE produce by :

a. Mast cells

b. B-cells

c. Plasma cells

d. T-cells

41 / 60

The following immunoglobulin can opsonize antigen during acute phase infection?:

a. IgG

b. IgE IgA

c. IgM

42 / 60

T-cell receptors or antibodies react with antigens:

a. Because both 'have light chain and heavy chain polypeptides

b. Because both are made by lymphocytes

c. Because they have specific receptors for antigen

d. Cause histamine release

43 / 60

The following answers is receptor for complement on immunoglobulins:

a. Hinge region

b. Fc region

c. Heavy chain

d. Fab region

44 / 60

The Live Attenuated Vaccines are used for the diseases below?:

a. Hepatitis A

b. Varicella zoster

c. Measles

d. All answers

45 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgE

b. IgM

c. IgA

d. IgG

46 / 60

The region of immunoglobulin term: Binds to various cellular receptors and to complement:

a. Heavy chain

b. Light chain

c. Fc region

d. Fab region

47 / 60

The drug to cure post exposure of HBV is?:

a. IgA

b. IgE

c. IgG

d. IgM

48 / 60

Which lymphocyte response to HBV infectin?:

a. B cells

b. Tc

c. Th

d. Macrophage

49 / 60

Histamine is secreted by:

a. Epithelial cell

b. White blood cells

c. Red blood cells

d. Mast cells

50 / 60

The following answers are function of B cell, EXCEPT?:

a. APC

b. Memory B cells

c. Complement cascade

d. Antibody secretion

51 / 60

All of the following are true for IgE molecules, EXCEPT:

a. They can cause the release of histamine.

b. They anti-parasitic immune responses.

c. They can fix complement.

d. They involved in allergic reactions.

52 / 60

All of the following are true about antibodies, EXCEPT:

a. They occur on the surface of B-lymphocyte

b. They are a single amino acid sequence

c. They are glycoproteins.

d. They fix complement.

53 / 60

Class II MHC are :

a. Recognized by the CD4 protein

b. Used to kill by cytotoxic T-cells

c. Not able to carry an antigen fragment

d. Used to participate in cytotoxic function

54 / 60

The followings statement are TRUE, EXCEPT :

a. MHC Class I generally occur on all cells of the immune system

b. MHC Class 1 bind antigen fragments and are recognized by the Tc-cell receptor

c. MHC Class II bind antigen and are recognized by the T-cell receptor and the CD4

d. MHC Class II carrying antigen presented to cytotoxic T cells

55 / 60

B cells recognised antigen presented by APC?:

a. Self – antigen

b. Nonself – antigen

c. T-independent antigen

d. T-dependent antigen

56 / 60

All of the following are true with respect to IgG antibodies, EXCEPT:

a. They mediate allergic reaction

b. They fix complement

c. They are glycoproteins

d. They occur on the surface of B lymphocytes

57 / 60

Class II MHC molecule works for?:

a. An antigen fragment

b. Tc function

c. B cell activation

d. T helper function

58 / 60

The much potent anaphylotoxin of the complement is:

a. C2b

b. C4a

c. C3a

d. C5a

59 / 60

All of these tests show that patient has been vaccinationated against HBV, EXCEPT?:

a. HBsAb positive

b. IgM positive

c. HBsAg negative

d. HBcAb Negative

60 / 60

Which organ does hepatitis affect?:

a. Heart

b. Liver

c. Brain

d. Kidneys

Your score is

The average score is 76%

Any comments?

Any problems/errors or mistakes found while testing, please let us know for modification!

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