Immunology Test

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Immunology Test

1 / 60

The following statements are true for Class III MHC molecules, EXCEPT :

a. Transport protein

b. Tc cells kill an infected cells

c. On the APC cells membrane

d. Recognized by the CD8

2 / 60

Which of the following DOES NOT play a role in antigen presentation:

a. MHC class II molecules

b. Complement

c. MHC class III molecules

d. MHC class I molecules

3 / 60

The following statements are true for IgE, EXCEPT:

a. Can cross the placental barrier

b. The least immunoglobulin in the plasma

c. They produce allergic reaction

d. They bind to mast cells

4 / 60

The following statement is for MHC Class I:

a. Participated in helper function

b. Recognized by the CD8 protein

c. Not able to carry an antigen fragment

d. Used to kill by cytotoxic T-cells

5 / 60

Which cell is directly secreted immunoglobulin:

a. Macrophage

b. Plasma cell

c. B lymphocyte

d. T lymphocyte

6 / 60

The function of immune system is to response:

a. All answers

b. Facilitated by T-cells

c. Mediated the humoral and cellular immune system

d. Can be facilitated by antibodies

7 / 60

The Cytotoxic T cells kill the cells/molecules below:

a. Bacteria

b. Infected cells

c. Extracellular antigen

d. Intracellular antigen

8 / 60

The following cells are cells mediated immunity in adaptive immune response?:

a. All answers

b. T cells

c. Tc cells

d. B cells

9 / 60

The percentage of TH cell among lymphocytes is?:

a. 19%

b. 46%

c. 23%

d. 7%

10 / 60

What is the term used to describe white blood cells migrating toward bacteria? :

a. Zeiosis

b. Phototaxis

c. Phagocytosis

d. Chemotaxis

11 / 60

One principal function of the Class I and Class II major histocompatibility complex is to :

a. Mediate immunoglobulin class

b. Present antigen for recognition by the T-cell receptor

c. Transduce the signal to the T-cell interior

d. Stimulate production of interleukins

12 / 60

The incubation period of HBV in the body is?:

a. 30-60 days

b. 45-180 days

c. 30-90 days

d. 60-100 days

13 / 60

In acute infection of Hepatitis B, the typical serologic course are:

a. HBcAb

b. HBsAb

c. HBsAg

d. HBcAg

14 / 60

The following statements are true for Antibodies:

a. Contain heavy and light chains

b. Contain no carbohydrate

c. Are made from alpha and beta chains

d. Are carbohydrates

15 / 60

The following statements are true for the antigenic determinant :

a. Small part of the antigen

b. Is the combining site of an antibody

c. Is paratope

d. Is paratope and Small part of the antigen

16 / 60

Which cell is T helper:

a. CD14

b. CD8

c. CD15

d. CD4

17 / 60

The followings statement are TRUE, EXCEPT:

a. MHC II bind antigen and recognized by the Th

b. MHC I presented on all cells of the immune

c. MHC I bind antigen and recognized by the Tc

d. MHC II carrying antigen presented to Tc

18 / 60

The C5 convertase of Classic and Lectin pathway is:

a. C4b2a4b

b. C4b2a3b

c. C4b2b3a

d. C3bBb3b

19 / 60

The following answers are function of B cell, EXCEPT?:

a. Complement cascade

b. APC

c. Memory B cells

d. Antibody secretion

20 / 60

The function of Natural Killer cell is:

a. Response to bacteria infection

b. Damaged the target cell membrane

c. Response to antibody

d. Kill pathogen

21 / 60

The following bonds is responsible for linking of antibody to its chains:

a. Disulfide bonds

b. Van der Waals forces

c. Hydrogen bonds

d. Hydrophobic forces

22 / 60

The following viral hepatitis are chronic hepatitis, EXCEPT?:

a. Heepatitis C

b. Hepatitis B

c. Hepatitis A

d. Hepatitis D

23 / 60

The Natural Killer T Cells work in the immune system :

a. Innate immunity

b. Adaptive immunity

c. Adaptive immunity and Innate immunity

d. Link between Adaptive and Innate immune

24 / 60

The following cells of immune system cam make inflammation:

a. Basophils

b. Mast cells and Basophils

c. Monocytes

d. Mast cells

25 / 60

Which type of cell destroys body cells that cause by infection?:

a. Plasma B cells

b. Memory B cells

c. Cytotoxic T cells

d. Memory T cells

26 / 60

The following answer is the best marker for Tc cells?:

a. CD3

b. CD8

c. CD21

d. CD4

27 / 60

The disease below can cause allergic reaction:

a. Asthma

b. Cancer

c. Thalassemia

d. Hepatitis

28 / 60

Immediate hypersensitivity reactions are below, EXCEPT:

a. Phagocytosis

b. If the antigen is an allergen

c. The consequence of antigen-antibody reactions

d. Result from histamine release

29 / 60

The receptor BCR for an antigen on the membrane of B cell is?:

a. Bivalent

b. Trivalent

c. Monovalent

d. None about

30 / 60

In the alternative pathway of the complement system, the factors below are useful to prevent the generation of C3 convertase :

a. C1-INH

b. Factor P

c. C3-BP

d. Factor F

31 / 60

What distinguishes helper T-cells from cytotoxic T-cells :

a. Cytotoxic cells recognize antigen complexed with MHC class I molecules and. Helper cells recognize antigen complexed with MHC class II molecules

b. Cytotoxic cells recognize antigen complexed with MHC class I molecules

c. Helper cells recognize antigen complexed with MHC class II molecules

d. Helper cells recognize antigen complexed with MHC class I molecules

32 / 60

These cells can be infected by Mycobacterium tuberculosis:

a. Eosinophil

b. Macrophage

c. Lymphocyte

d. Neutrophil

33 / 60

How many receptors for antigen on the surface of B lymphocyte:

a. 10

b. 1

c. 4

d. 2

34 / 60

The following viral hepatitis is enteric hepatitis?:

a. Heepatitis C

b. Hepatitis B

c. Hepatitis D

d. Hepatitis A

35 / 60

How many receptors for antigen on the surface of T lymphocyte:

a. 10

b. 1

c. 4

d. 2

36 / 60

The Complement that gives Anaphylotoxin much potent is:

a. C3a

b. C4a

c. C5a

d. C2b

37 / 60

The function of major histocompatibility complex is:

a. Bind epitope for presentation to T-cells

b. Bind antibody for cytokine secretion

c. Degrade T4 and T8 polypeptides

d. Bind complement for cell lysis

38 / 60

Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Rabies

b. Pertussis

c. Hepatitis B

d. Polio

39 / 60

The variable regions in the light chains participate in:

a. Fc receptor binding.

b. Affinity of the complement receptors.

c. Epitope binding.

d. Interaction of the Fab with cytokines.

40 / 60

The function of Class III MHC proteins are :

a. Transport complement protein

b. Lyse antigen

c. Recognized antigen by CD4

d. Recognized antigen by CD8

41 / 60

The followings statement are TRUE, EXCEPT :

a. MHC Class 1 bind antigen fragments and are recognized by the Tc-cell receptor

b. MHC Class I generally occur on all cells of the immune system

c. MHC Class II carrying antigen presented to cytotoxic T cells

d. MHC Class II bind antigen and are recognized by the T-cell receptor and the CD4

42 / 60

The immunoglobulin class which is the second abundant in the normal adult is:

a. IgA

b. IgE

c. IgD

d. IgG

43 / 60

One principal function of the Class I and Class II major histocompatibility complex is to:

a. Transduce the signal to the T-cell interior

b. Stimulate production of interleukins

c. Mediate immunoglobulin class

d. Help T cell for the recognition Antigen

44 / 60

The followings statement are TRUE for Target cell lysis and destruction,EXCEPT :

a. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

b. Perforin released from antigen-specific cytotoxic T-cells

c. Complement binding to IgE antibodies which have bound to epitopes on the cell surface

d. Complement binding to IgG and IgM which have bound to epitopes on the target cell

45 / 60

The following statement are for Class I MHC proteins, EXCEPT:

a. Able to carry an antigen fragment

b. Participate in T helper function

c. Recognized by the CD8 protein

d. Killed target cells by Tc cells

46 / 60

The following statements are true for Immunoglobins, EXCEPT:

a. Are antibodies

b. Possess both variable and constant regions

c. All have receptors for complement

d. Five major classes IgM, IgG, IgA, IgD, IgE

47 / 60

One principal function of complement is to:

a. Mediate the release of histamine

b. Bind antibodies attached to cell surfaces and to lyse these cells

c. Inactivate perforins

d. Phagocytize antigens

48 / 60

Class II MHC proteins are :

a. Recognized by CD4

b. Recognized by CD4 and Used to participate in helper function

c. Recognized by CD8

d. Used to participate in helper function

49 / 60

Immunoglobulins do which of the following?:

a. Antigen binding

b. All of the above

c. Opsonisation

d. Complement fixation

50 / 60

The component of immune system that can cause fever is :

a. Immunoglobulin

b. Complement

c. Macrophage

d. T lymphocytes

51 / 60

Immunoglobulins are chemically:

a. D. Lipo-proteins

b. Glycogens

c. Glycolipids

d. Glycoproteins

52 / 60

The following statement are for Target cell lysis and destruction, EXCEPT:

a. Complement binding to IgE which have bound to epitopes on the cell surface

b. Perforin released from antigen-specific cytotoxic T-cells

c. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

d. Complement binding to IgG and IgM which have bound to epitopes on the target cell

53 / 60

Which of the following statements about leukocyte function is false?:

a. Eosinophils kill parasites

b. Neutrophils phagocytose pathogens .

c. Leukocytes are cells of the immune response.

d. Eosinophils release histamine .

54 / 60

T-cell receptors or antibodies react with antigens:

a. Because both 'have light chain and heavy chain polypeptides

b. Because they have specific receptors for antigen

c. Because both are made by lymphocytes

d. Cause histamine release

55 / 60

Light chains are:

a. Have only a constant region

b. Not specific for each class of antibody

c. Specific for each class of antibody

d. Reactive with antigen

56 / 60

Antigen-antibody reactions can result in the following:

a. Complement fixation

b. Killed antigen

c. All answers

d. Virus neutralization

57 / 60

The major histocompatibility complex proteins function to:

a. Bind antigen for presentation to T-cells

b. Bind complement for cell lysis

c. Bind antibody for lymphokine production

d. Degrade T4 and T8 polypeptides

58 / 60

In chronic infection of hepatitis B, the antigen persists in the whole life are?:

a. HBeAg

b. HBsAg

c. All answers

d. HBcAg

59 / 60

The function of major histocompatibility complex for antigen in the cytosol is:

a. Presentation antigen to Tc-cells

b. Presentation antigen to Th-cells

c. Transport protein

d. Bind complement for cell lysis

60 / 60

Which type of antibody is not effective in activating complement?:

a. IgG4

b. IgG1

c. IgG2

d. IgG3

Your score is

The average score is 74%

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