Immunology Test

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Immunology Test

1 / 60

Which of these cell types can play a primary role in attacking and killing cancer cells?:

a. T cell

b. Platelet

c. Cytotoxic

d. Mast cell

2 / 60

Which of the following organ is primarily infected by Hepatitis viruses?:

a. Spleen

b. Liver

c. Intestines

d. Lung

3 / 60

These cytokines secreted by T helper cell?:

a. Chimokine

b. TNF-α

c. IL-2

d. Interferon

4 / 60

Regulatory T cells (Treg cells), formerly known as ?:

a. Natural T reg

b. CD4+ T reg

c. Suppressor T cells

d. Adaptive T reg

5 / 60

The Complement that produce anaphylactic much more potent is:

a. C2b

b. C5a

c. C3a

d. C4a

6 / 60

Which of the following components of the adaptive immune system secretes immunoglobulin
(Ig)?:

a. Activated B cell (plasma cell)

b. CD8+ cytotoxic T cell (CTL)

c. CD4+ activated T cell

d. Resting lymphocytes (B cell, T cell)

7 / 60

The immunoglobulin Joining chain (J-chain) is:

a. Produced by T-Cells

b. Associated with IgM and IgG

c. Associated with IgM and IgA

d. Produced by mast cells

8 / 60

What distinguishes helper T-cells from cytotoxic T-cells:

a. Th recognize antigen with MHC I

b. Tc recognize antigen with MHC I and Th recognize antigen with MHC II

c. Th recognize antigen with MHC II

d. Tc recognize antigen with MHC I

9 / 60

The tests below show that patient is susceptible to an HBV infection?:

a. HBsAg negative

b. HBcAb negative

c. HBsAb negative

d. All answers

10 / 60

The following answer is the function of IgM, EXCEPT :

a. Opsonize bacteries

b. Cross placenta

c. Primary response to antigen

d. Activate complement

11 / 60

The basic monomeric Immunoglobulin unit is:

a. One of five major classes

b. Four polypeptide chains and One of five major classes

c. Four polypeptide chains

d. Synthesized by a T-cell

12 / 60

The following vaccines are Live Attenuated Vaccines, EXCEPT?:

a. Hepatitis A

b. Tetanus

c. Varicella

d. Polio

13 / 60

The hapten carrier conjugate can activate B cells to secrete antibody :

a. Immunoglobulin

b. Immunoglobulin-Epitope

c. Antigenic determinant

d. Antigen

14 / 60

B cells recognised antigen presented by APC?:

a. T-independent antigen

b. Self – antigen

c. T-dependent antigen

d. Nonself – antigen

15 / 60

The factor that dissociated the initiation of C1qrs in the classical pathway is:

a. Factor P

b. Factor F

c. C1-INH

d. C3-BP

16 / 60

T- independent antigen presented to the following lymphocyte?:

a. TH1 cell

b. TH cells

c. B cells

d. Tc cells

17 / 60

The functional activity of the T-cell:

a. All answers

b. Is related with CD4 or CD8 associated polypeptides

c. Can be mediated through cytokines

d. Occurs after recognition of an epitope

18 / 60

The much potent anaphylotoxin of the complement is:

a. C5a

b. C2b

c. C3a

d. C4a

19 / 60

Individuals make up over C4a would be expected to have:

a. Anaphylaxia

b. Bacteria

c. Diabetis

d. Liver disease

20 / 60

The following answer is the function of IgG, EXCEPT :

a. Activate complement

b. Opsonize bacteries

c. Primary response to antigen

d. Cross placenta

21 / 60

Which of the immune cells/molecules are effective to neutralise and opsonse extracellular
pathogens?:

a. B cells

b. Complement

c. Antibodies

d. T cells

22 / 60

Which of the following statements about leukocyte function is false?:

a. Leukocytes are cells of the immune response.

b. Neutrophils phagocytose pathogens .

c. Eosinophils release histamine .

d. Eosinophils kill parasites

23 / 60

Which of the following statements about leukocyte function is false?:

a. Neutrophils engulf damaged cells and pathogens by phagocytosis.

b. Macrophages are phagocytic cells that are involved in the adaptive response.

c. Eosinophils deliver toxic granules to kill parasites. They are also involved in allergic reactions.

d. Leukocytes are involved in the immune response.

24 / 60

The cells that have azerophilic granule to facilitate phagocytosis is:

a. Neutrophils

b. Basophils

c. Mast cells

d. Monocytes

25 / 60

The followings statement are TRUE for Target cell lysis and destruction,EXCEPT :

a. Complement binding to IgE antibodies which have bound to epitopes on the cell surface

b. Perforin released from antigen-specific cytotoxic T-cells

c. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

d. Complement binding to IgG and IgM which have bound to epitopes on the target cell

26 / 60

The function of major histocompatibility complex is:

a. Bind complement for cell lysis

b. Bind epitope for presentation to T-cells

c. Bind antibody for cytokine secretion

d. Degrade T4 and T8 polypeptides

27 / 60

The C5 convertase of Alternative pathway is:

a. C4b2a4b

b. C4b2a3b

c. C3bBb3b

d. C4b2b3a

28 / 60

In the complement system, the classic pathway initiates by the complement :

a. C5

b. MBL

c. C4

d. C1qrs

29 / 60

The drug to cure post exposure of HBV is?:

a. IgE

b. IgG

c. IgM

d. IgA

30 / 60

Immunity acquired after an infection is?:

a. Passive immunity

b. Response immunity

c. Innate immunity

d. Active immunity

31 / 60

T-cell receptors or antibodies react with antigens:

a. Because both 'have light chain and heavy chain polypeptides

b. Because both are made by lymphocytes

c. Because they have specific receptors for antigen

d. Cause histamine release

32 / 60

The vaccine prepared from living and inactivated microbe is considered as?:

a. Denatured

b. Atenuated vaccin

c. Antibody

d. A toxoid

33 / 60

All of the following are true about antibodies, EXCEPT:

a. They fix complement.

b. They are polypeptide

c. They are glycoproteins.

d. They occur on the surface of B-lymphocyte

34 / 60

The class of an immunoglobulin is determined by:

a. The light chain

b. The heavy chain

c. The antigen

d. Class I and II MHC

35 / 60

When hepatitis vaccin start to use since year?:

a. 199000%

b. 2002

c. 1985

d. 1960

36 / 60

Each of the following statement is a characteristic of antibodies, EXCEPT:

a. They are phagocytes

b. They contain variable region

c. They have specific receptor for antigen

d. They have four glycoprotein chains

37 / 60

The following immunoglobulin is used to produe vaccine?:

a. IgA

b. IgG4

c. IgM

d. IgG

38 / 60

Which of the following components of the innate immune system involves the release of
histamine?:

a. Eosinophil

b. Macrophage

c. Neutrophil

d. Tissue mast cell

39 / 60

The function of LGL cell is:

a. Respose to tumor cells

b. Response to bacteria infection

c. Response to antibody

d. Kill pathogen

40 / 60

The fragment of Antigen is called:

a. Antigenic determinant

b. Immunogen

c. Immunoglbulin

d. Hapten

41 / 60

The function of T cytotoxic lymphocyte is?:

a. Lyse pathogen

b. Lyse target cell

c. Lyse paasite

d. Lyse bacterie

42 / 60

The first immunoglobulin secreted by B cells to make up memory cells is?:

a. IgA

b. IgD

c. IgM

d. IgG

43 / 60

B and T cells are produced by stem cells located in:?:

a. Liver

b. Circulatery system

c. Bone marrow

d. Spleen

44 / 60

The type of an immunoglobulin is determined by:

a. The variable region

b. The heavy chain

c. The light chain

d. The carbohydrate

45 / 60

Pepsin cleaves what region of immunoglobulin?:

a. Heavy chain

b. Light chain

c. Hinge region

d. Heavy chain and Light chain

46 / 60

The following hepatitis can be prevented by vaccination :

a. Hepatitis A and B

b. Hepatitis B and C

c. Hepatitis D and C

d. Hepatitis C and E

47 / 60

Which of the following immune cells/molecules are most effective to destroying intracellular
pthogens ?:

a. B cells

b. T cytotoxic cells

c. T helper cells

d. Plasma cells

48 / 60

The family of hepatitis C virus is?:

a. Flavivirus

b. Rotavirus

c. Hepanavirus

d. Ribovirus

49 / 60

The following cells of immune system cam make IgE:

a. Mast cells and Eosinophils

b. Mast cells

c. Monocytes

d. Eosinophils

50 / 60

The following receptor is for T cells?:

a. Toll like receptor

b. BCR

c. Scavenger receptor

d. TCR

51 / 60

The following statement are for Class I MHC proteins, EXCEPT:

a. Participate in T helper function

b. Recognized by the CD8 protein

c. Able to carry an antigen fragment

d. Killed target cells by Tc cells

52 / 60

Biological effect of Complement C2b is:

a. Edema

b. Opsonisation

c. Phagocytosis

d. Anaphylaxis

53 / 60

The disease below can cause allergic reaction:

a. Thalassemia

b. Cancer

c. Hepatitis

d. Asthma

54 / 60

IgE produce by :

a. Mast cells

b. B-cells

c. Plasma cells

d. T-cells

55 / 60

Which kind of cells worked in innate immune system and response to the tumor cells?:

a. T cells

b. NK cells

c. Macropages

d. B cells

56 / 60

The following statement are MOST closely related to each, EXCEPT:

a. Epitope

b. Antibody

c. Allergen

d. Antigen

57 / 60

The component of immune system that can cause fever is :

a. Macrophage

b. Complement

c. Immunoglobulin

d. T lymphocytes

58 / 60

All of the following are true with respect to IgG antibodies, EXCEPT:

a. They occur on the surface of B lymphocytes

b. They mediate allergic reaction

c. They are glycoproteins

d. They fix complement

59 / 60

Complements are chemically:

a. Proteins

b. Glycoproteins

c. Glycogens

d. Lipoproteins

60 / 60

The following statements are true for Class I MHC molecules, EXCEPT :

a. Participated in Th function

b. Tc cells kill an infected cells

c. On the APC cells membrane

d. Recognized by the CD8

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