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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

The type of T-cells that destroy host cells bearing foreign antigen:

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2)

The classical pathway of complement activation is:

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3)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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4)

The antigen-antibody interactions occur in:

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5)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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6)

The circulation of a two month old breast-fed baby will contain maternal:

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7)

All are mechanism of action of complement but except:

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8)

An antigen is:

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9)

All are the measure for post rabies exposure prophylaxis, but except one?

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10)

What is the mode of administration for PCV-13 vaccine?

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11)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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12)

Which of the following statements are true regarding polio vaccines:

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13)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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14)

Newborns get their antibodies from mother’s milk. This is an example of?

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15)

Infectious material from what illness was used to develop the first vaccine?

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16)

The bonds involved in antigen-antibody interactions are

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17)

What vaccine can be used for pregnant women?

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18)

Serum which contains antibodies is called:

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19)

All are immune cells in innate immune system but except:

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20)

Which of the following antibody types forms a pentamer?

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21)

Graft and tumor rejection are mediated primarily by:

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22)

Injection of immunoglobulin is:

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23)

The technology used for the production of monoclonal antibodies is:

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24)

The impact is:

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25)

The immunoglobulins transport across placenta mostly:

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26)

All are important characteristics of innate immunity but except:

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27)

The herd immunity is:

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28)

The complement system involved in the inflammation are:

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29)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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30)

Small chemical groups on the antigen molecule that can react with antibody

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31)

Which antibody is the first to be released into the blood following an infection?

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32)

In order to elicit an immune response, a carbohydrate must be which of the following?

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33)

The Adverse events following immunization (AEFI) are divided into:

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34)

What is the mode of administration for anti-measles vaccine?

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35)

The immunoglobulins participated in complement system formation are:

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36)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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37)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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38)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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39)

In the application Antigen- Antibody reaction, which one is correct?

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40)

All are functions of immunoglobulins but except:

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41)

The immune cells that is linked between innate and adaptive immunity are:

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42)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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43)

The class II MHC molecule appeared to bind with receptor of:

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44)

The complement system consists of about:

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45)

Which of the following statement is true regarding vaccination:

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46)

The immune cells that is linked between innate and adaptive immunity are:

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47)

The cytotoxic T-cells is involved in:

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48)

The following statements are criteria for a good vaccine but which is incorrect statement?

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49)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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50)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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51)

An immunoglobulin is a:

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52)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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53)

Adjuvant used in HPV vaccine is:

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54)

The classical pathway of complement activation is:

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55)

What is the immune cell in adaptive immunity?

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56)

Which of the following is not the function of antibody?

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57)

The following statements are the use of passive immunization included but except one?

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58)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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59)

All the following comes under non-specific defence mechanism except

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60)

In the application Antigen- Antibody reaction, which one is correct?

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61)

All the given vaccines are attenuated or inactivated whole pathogen except:

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62)

What is the mode of administration for BCG vaccine?

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63)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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64)

An epitope is:

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65)

The first line of defense against invading pathogens:

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66)

Vaccination is an example of?

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67)

Natural humoral immune response against a pathogen leads to the production of:

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68)

The class I MHC molecule appeared to bind with receptor of:

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69)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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70)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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71)

The adverse effects of vaccines are linked to:

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72)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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73)

All are examples of names of monoclonal antibodies but except one?

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74)

Which of the following antibodies have a positive effect on babies through breast feeding?

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75)

Several of the complement components are:

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76)

All are therapeutic applications of polyclonal antibodies but except one?

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77)

All are factors influencing in immunogenicity but except:

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78)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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79)

The naive T cells are:

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80)

The general principle of vaccination was established by:

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81)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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82)

The effectiveness is:

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83)

The immunoglobulins transport across epithelium:

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84)

Injection of anti-venom to a patient for snake bite is example of?

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85)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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86)

In the application Antigen- Antibody reaction, which one is correct?

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87)

In the application Antigen- Antibody reaction, which one is not correct?

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88)

Adjuvant used in HBV vaccine is:

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89)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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90)

Mode of IPV vaccine administration is:

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91)

The role of the macrophage during an antibody response is to:

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92)

Antigen presenting cells for vaccine are:

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93)

Which of the following statement is true

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94)

An epitope:

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95)

All are Antigen-Presenting Cells (APCs) but except:

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96)

The efficacy is:

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97)

The first recombinant antigen vaccine approved for human use is:

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98)

In an immune response the type of cell which gets activated earliest is:

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99)

The characteristic of antigen-antibody interactions occur in primary stage:

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100)

The complement system involved in chemotaxis are:

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101)

The Follicular Dendritic Cells (FDCs) is located in:

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102)

All are 3 main effects of complement but except:

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103)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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104)

Primary lymphoid organs include

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105)

The main advantage of passive immunization over active immunization is that:

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106)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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107)

The characteristic of antigen-antibody interactions occur in second stage:

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108)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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109)

The antibody-binding site is formed primarily by:

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110)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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111)

The process of weakening a pathogen is called:

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112)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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113)

What vaccine should be avoided for the pregnant woman?

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114)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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115)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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116)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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117)

Which of the following is not an ideal property of a vaccine?

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118)

What vaccine should not be frozen:

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119)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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120)

What is a live attenuated vaccine?

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121)

The purpose of clinical trial of a vaccine is:

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122)

Immunogen is:

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123)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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124)

Which of the following is the site of T cell maturation?

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125)

The complement system are synthesized by:

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126)

The complement system involved in phagocytic function are:

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127)

Which of the following is a polysaccharide vaccine:

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128)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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129)

Successful immunization can be impaired by:

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130)

Tetanus toxoid is usually given to humans:

Your score is

The average score is 58%

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