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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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2)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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3)

What vaccine should not be frozen:

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4)

The Adverse events following immunization (AEFI) are divided into:

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5)

The complement system involved in phagocytic function are:

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6)

An immunoglobulin is a:

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7)

The first line of defense against invading pathogens:

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8)

What is a live attenuated vaccine?

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9)

The antigen-antibody interactions occur in:

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10)

All are mechanism of action of complement but except:

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11)

In the application Antigen- Antibody reaction, which one is not correct?

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12)

What vaccine can be used for pregnant women?

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13)

All are 3 main effects of complement but except:

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14)

Injection of anti-venom to a patient for snake bite is example of?

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15)

The following statements are criteria for a good vaccine but which is incorrect statement?

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16)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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17)

The purpose of clinical trial of a vaccine is:

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18)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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19)

Newborns get their antibodies from mother’s milk. This is an example of?

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20)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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21)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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22)

All are examples of names of monoclonal antibodies but except one?

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23)

Serum which contains antibodies is called:

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24)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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25)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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26)

The cytotoxic T-cells is involved in:

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27)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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28)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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29)

The role of the macrophage during an antibody response is to:

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30)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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31)

The bonds involved in antigen-antibody interactions are

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32)

The first recombinant antigen vaccine approved for human use is:

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33)

All are functions of immunoglobulins but except:

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34)

The impact is:

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35)

Natural humoral immune response against a pathogen leads to the production of:

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36)

In the application Antigen- Antibody reaction, which one is correct?

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37)

The main advantage of passive immunization over active immunization is that:

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38)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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39)

The herd immunity is:

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40)

The classical pathway of complement activation is:

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41)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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42)

Which of the following antibodies have a positive effect on babies through breast feeding?

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43)

The complement system involved in chemotaxis are:

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44)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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45)

Adjuvant used in HBV vaccine is:

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46)

The general principle of vaccination was established by:

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47)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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48)

The effectiveness is:

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49)

What is the mode of administration for anti-measles vaccine?

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50)

Adjuvant used in HPV vaccine is:

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51)

All are therapeutic applications of polyclonal antibodies but except one?

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52)

Which of the following is a polysaccharide vaccine:

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53)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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54)

Small chemical groups on the antigen molecule that can react with antibody

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55)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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56)

In the application Antigen- Antibody reaction, which one is correct?

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57)

In the application Antigen- Antibody reaction, which one is correct?

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58)

The complement system involved in the inflammation are:

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59)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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60)

Antigen presenting cells for vaccine are:

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61)

The complement system are synthesized by:

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62)

Which of the following antibody types forms a pentamer?

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63)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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64)

Several of the complement components are:

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65)

An antigen is:

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66)

The class I MHC molecule appeared to bind with receptor of:

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67)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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68)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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69)

An epitope is:

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70)

All are Antigen-Presenting Cells (APCs) but except:

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71)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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72)

All are immune cells in innate immune system but except:

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73)

The efficacy is:

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74)

The following statements are the use of passive immunization included but except one?

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75)

Primary lymphoid organs include

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76)

The type of T-cells that destroy host cells bearing foreign antigen:

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77)

The immunoglobulins transport across epithelium:

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78)

Which of the following statement is true

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79)

In order to elicit an immune response, a carbohydrate must be which of the following?

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80)

What is the mode of administration for PCV-13 vaccine?

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81)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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82)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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83)

The naive T cells are:

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84)

Mode of IPV vaccine administration is:

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85)

The adverse effects of vaccines are linked to:

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86)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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87)

The class II MHC molecule appeared to bind with receptor of:

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88)

The technology used for the production of monoclonal antibodies is:

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89)

The Follicular Dendritic Cells (FDCs) is located in:

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90)

The immune cells that is linked between innate and adaptive immunity are:

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91)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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92)

The process of weakening a pathogen is called:

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93)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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94)

The characteristic of antigen-antibody interactions occur in second stage:

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95)

Infectious material from what illness was used to develop the first vaccine?

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96)

All are the measure for post rabies exposure prophylaxis, but except one?

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97)

In an immune response the type of cell which gets activated earliest is:

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98)

All are important characteristics of innate immunity but except:

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99)

An epitope:

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100)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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101)

Which of the following statement is true regarding vaccination:

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102)

All are factors influencing in immunogenicity but except:

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103)

The complement system consists of about:

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104)

Which of the following is not the function of antibody?

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105)

What vaccine should be avoided for the pregnant woman?

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106)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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107)

The characteristic of antigen-antibody interactions occur in primary stage:

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108)

The immunoglobulins participated in complement system formation are:

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109)

Vaccination is an example of?

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110)

What is the immune cell in adaptive immunity?

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111)

The circulation of a two month old breast-fed baby will contain maternal:

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112)

Successful immunization can be impaired by:

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113)

What is the mode of administration for BCG vaccine?

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114)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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115)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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116)

The antibody-binding site is formed primarily by:

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117)

All the given vaccines are attenuated or inactivated whole pathogen except:

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118)

Which antibody is the first to be released into the blood following an infection?

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119)

The immune cells that is linked between innate and adaptive immunity are:

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120)

Graft and tumor rejection are mediated primarily by:

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121)

Tetanus toxoid is usually given to humans:

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122)

Injection of immunoglobulin is:

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123)

Which of the following is not an ideal property of a vaccine?

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124)

All the following comes under non-specific defence mechanism except

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125)

Immunogen is:

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126)

The classical pathway of complement activation is:

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127)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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128)

Which of the following is the site of T cell maturation?

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129)

Which of the following statements are true regarding polio vaccines:

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130)

The immunoglobulins transport across placenta mostly:

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