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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

In order to elicit an immune response, a carbohydrate must be which of the following?

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2)

An epitope is:

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3)

The Follicular Dendritic Cells (FDCs) is located in:

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4)

The cytotoxic T-cells is involved in:

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5)

The following statements are criteria for a good vaccine but which is incorrect statement?

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6)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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7)

In the application Antigen- Antibody reaction, which one is not correct?

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8)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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9)

Antigen presenting cells for vaccine are:

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10)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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11)

Injection of immunoglobulin is:

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12)

What is the immune cell in adaptive immunity?

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13)

Which of the following statement is true

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14)

Which of the following is the site of T cell maturation?

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15)

The class I MHC molecule appeared to bind with receptor of:

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16)

What is the mode of administration for PCV-13 vaccine?

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17)

Which of the following is not the function of antibody?

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18)

The efficacy is:

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19)

What is a live attenuated vaccine?

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20)

The complement system consists of about:

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21)

Primary lymphoid organs include

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22)

Tetanus toxoid is usually given to humans:

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23)

The characteristic of antigen-antibody interactions occur in second stage:

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24)

The type of T-cells that destroy host cells bearing foreign antigen:

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25)

Vaccination is an example of?

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26)

The Adverse events following immunization (AEFI) are divided into:

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27)

Newborns get their antibodies from mother’s milk. This is an example of?

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28)

What is the mode of administration for BCG vaccine?

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29)

All are mechanism of action of complement but except:

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30)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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31)

The antigen-antibody interactions occur in:

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32)

All the given vaccines are attenuated or inactivated whole pathogen except:

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33)

Adjuvant used in HBV vaccine is:

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34)

Serum which contains antibodies is called:

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35)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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36)

What vaccine should not be frozen:

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37)

The effectiveness is:

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38)

All are therapeutic applications of polyclonal antibodies but except one?

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39)

What vaccine can be used for pregnant women?

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40)

The circulation of a two month old breast-fed baby will contain maternal:

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41)

The class II MHC molecule appeared to bind with receptor of:

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42)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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43)

An antigen is:

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44)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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45)

Small chemical groups on the antigen molecule that can react with antibody

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46)

All are examples of names of monoclonal antibodies but except one?

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47)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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48)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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49)

The process of weakening a pathogen is called:

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50)

The immune cells that is linked between innate and adaptive immunity are:

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51)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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52)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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53)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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54)

Several of the complement components are:

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55)

What is the mode of administration for anti-measles vaccine?

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56)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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57)

The first recombinant antigen vaccine approved for human use is:

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58)

The following statements are the use of passive immunization included but except one?

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59)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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60)

The immunoglobulins transport across placenta mostly:

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61)

The antibody-binding site is formed primarily by:

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62)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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63)

The role of the macrophage during an antibody response is to:

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64)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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65)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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66)

The complement system are synthesized by:

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67)

The characteristic of antigen-antibody interactions occur in primary stage:

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68)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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69)

The technology used for the production of monoclonal antibodies is:

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70)

In the application Antigen- Antibody reaction, which one is correct?

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71)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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72)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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73)

The main advantage of passive immunization over active immunization is that:

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74)

The bonds involved in antigen-antibody interactions are

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75)

An epitope:

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76)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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77)

Adjuvant used in HPV vaccine is:

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78)

Which antibody is the first to be released into the blood following an infection?

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79)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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80)

The classical pathway of complement activation is:

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81)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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82)

In an immune response the type of cell which gets activated earliest is:

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83)

The first line of defense against invading pathogens:

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84)

Which of the following statements are true regarding polio vaccines:

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85)

Which of the following is a polysaccharide vaccine:

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86)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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87)

The impact is:

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88)

What vaccine should be avoided for the pregnant woman?

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89)

Graft and tumor rejection are mediated primarily by:

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90)

All are factors influencing in immunogenicity but except:

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91)

All are immune cells in innate immune system but except:

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92)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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93)

The immune cells that is linked between innate and adaptive immunity are:

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94)

All are Antigen-Presenting Cells (APCs) but except:

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95)

All are functions of immunoglobulins but except:

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96)

The herd immunity is:

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97)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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98)

The adverse effects of vaccines are linked to:

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99)

All are important characteristics of innate immunity but except:

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100)

An immunoglobulin is a:

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101)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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102)

Mode of IPV vaccine administration is:

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103)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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104)

The classical pathway of complement activation is:

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105)

The naive T cells are:

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106)

All the following comes under non-specific defence mechanism except

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107)

The complement system involved in the inflammation are:

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108)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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109)

The complement system involved in chemotaxis are:

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110)

Infectious material from what illness was used to develop the first vaccine?

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111)

Which of the following statement is true regarding vaccination:

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112)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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113)

In the application Antigen- Antibody reaction, which one is correct?

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114)

The general principle of vaccination was established by:

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115)

The immunoglobulins transport across epithelium:

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116)

Successful immunization can be impaired by:

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117)

In the application Antigen- Antibody reaction, which one is correct?

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118)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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119)

All are the measure for post rabies exposure prophylaxis, but except one?

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120)

The immunoglobulins participated in complement system formation are:

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121)

Natural humoral immune response against a pathogen leads to the production of:

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122)

The purpose of clinical trial of a vaccine is:

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123)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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124)

Which of the following antibodies have a positive effect on babies through breast feeding?

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125)

The complement system involved in phagocytic function are:

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126)

Which of the following antibody types forms a pentamer?

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127)

Injection of anti-venom to a patient for snake bite is example of?

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128)

Which of the following is not an ideal property of a vaccine?

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129)

All are 3 main effects of complement but except:

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130)

Immunogen is:

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