Immunologie Test 0% 26 votes, 4.8 avg 0 You will have 60 minutes to complete all the questions. After the timer reaches 60 minutes, the exam will end and be saved automatically. Good luck! *Fingers crossed* The timer has been reached. The exam has now been terminated and saved. Immunologie Test 1 / 60 What type of immune response involves HLA molecules? a. ) Innate immunity b. ) Both innate and adaptive immunity c. ) Passive immunity d. ) Adaptive immunity 2 / 60 The function of C3 convertase is to: a. ) Directly lyse pathogens b. ) Inhibit complement activation c. ) Initiate cytokine release d. ) Activate CD8+ T cells e. ) Convert C3 into C3a and C3b 3 / 60 What is the final stage of an immune response? a. ) Activation of B cells b. ) Complement activation c. ) Recognition of antigens d. ) Resolution and memory formation e. ) Cytotoxic attack 4 / 60 In a competitive ELISA, how is antigen concentration determined? a. ) Based on light scattering b. ) By antigen migration on a strip c. ) Directly proportional to signal d. ) Inversely proportional to signal e. ) Through radioactivity measurement 5 / 60 Which test is used for next-generation sequencing (NGS) of viruses? a. ) Hemagglutination b. ) PCR c. ) Nanopore sequencing d. ) ELISA e. ) Plaque assay 6 / 60 What does TCIDβ β measure? a. ) Virus protein expression b. ) Viral genome sequencing c. ) Number of antibodies d. ) Virus concentration that infects 50% of cultured cells e. ) Viral RNA copies 7 / 60 What type of immunity is transferred from mother to child via breast milk? a. ) Passive natural b. ) Cell-mediated immunity c. ) Active artificial d. ) Passive artificial e. ) Active natural 8 / 60 Which of the following diseases is most closely associated with C3 deficiency? a. ) Hereditary angioedema b. ) Systemic lupus erythematosus (SLE) c. ) Recurrent bacterial infections d. ) Macular degeneration e. ) Atypical hemolytic uremic syndrome (aHUS) 9 / 60 Which HLA class is involved in organ transplant compatibility? a. ) Class II b. ) Both Class I and Class II c. ) None of the above d. ) Class III e. ) Class I 10 / 60 Which part of the immune system produces antibodies? a. ) B cells b. ) T cells c. ) Neutrophils d. ) Macrophages e. ) Natural killer cells 11 / 60 Which of the following is true about haptens a. ) They activate T cells directly without requiring a larger carrier molecule b. ) They are small molecules that can induce an immune response only when bound to larger molecules c. ) They are always part of bacteria d. ) They are large proteins that can act as antigens without a carrier e. ) They can only bind to IgE antibodies 12 / 60 Which organ is responsible for the production of all blood cells? a. ) Spleen b. ) Bone marrow c. ) Lymph nodes d. ) Liver e. ) Thymus 13 / 60 Which molecules do APCs use to present antigens to T cells? a. ) Cytokines b. ) Chemokines c. ) Major Histocompatibility Complex (MHC) d. ) Toll-like receptors e. ) Antibodies 14 / 60 What is the key advantage of immunochromatographic assays? a. ) Use of radioisotopes b. ) High specificity c. ) Requirement of advanced laboratory equipment d. ) Rapid results e. ) Long processing time 15 / 60 Which of the following is a characteristic of innate immunity? a. ) Specific response b. ) Memory formation c. ) Fast response d. ) Recognition of specific antigens e. ) Activation of T cells 16 / 60 What triggers inflammation? a. ) Release of histamines and cytokines b. ) Memory cell formation c. ) T cell activation d. ) Complement activation e. ) Phagocytosis 17 / 60 Which of the following is NOT a feature of AIDS? a. ) Development of certain cancers b. ) Severe immunosuppression c. ) High CD4+ T cell count d. ) Progressive depletion of CD4+ T cells e. ) Increased susceptibility to opportunistic infections 18 / 60 What is the role of Helper T cells (CD4βΊ)? a. ) Suppress immune response b. ) Destroy infected cells c. ) Activate other immune cells d. ) Produce antibodies e. ) Engulf pathogens 19 / 60 Which of the following is NOT a form of passive immunotherapy? a. ) mRNA vaccines b. ) Administration of antitoxins c. ) Convalescent plasma therapy d. ) Intravenous immunoglobulin (IVIG) e. ) Monoclonal antibody therapy 20 / 60 Which of these molecules does NOT belong to the HLA system? a. ) HLA-C b. ) HLA-DR c. ) HLA-B d. ) HLA-A e. ) HLA-M 21 / 60 Which of the following is a feature of HIV-2 compared to HIV-1? a. ) HIV-2 is resistant to all treatments. b. ) HIV-2 has a longer asymptomatic phase. c. ) HIV-2 is more easily transmitted. d. ) HIV-2 infects a broader range of cells. e. ) HIV-2 causes AIDS more rapidly than HIV-1. 22 / 60 What type of ELISA is best for detecting cytokines in a biological sample? a. ) Competitive b. ) Direct c. ) Indirect d. ) Sandwich 23 / 60 Which immune cells are responsible for killing virus-infected cells? a. ) B cells b. ) Helper T cells c. ) Basophils d. ) Macrophages e. ) Cytotoxic T cells (CD8βΊ) 24 / 60 What is the primary structure that defines the antigen-binding site of an antibody? a. ) Heavy chain b. ) Constant region c. ) Fc region d. ) Variable region e. ) Light chain 25 / 60 Which immunoglobulin is the most abundant in the blood and extracellular fluid? a. ) IgE b. ) IgG c. ) IgA d. ) IgM e. ) IgD 26 / 60 Patients with terminal complement component deficiency should receive which vaccination? a. ) Hepatitis B vaccine b. ) Meningococcal vaccine c. ) MMR vaccine d. ) Influenza vaccine e. ) Diphtheria vaccine 27 / 60 What does the “MHC” in MHC molecules stand for? a. ) Major Hemoglobin Complex b. ) Molecular Histone Complex c. ) Major Histocompatibility Complex d. ) Membrane Hemoglobin Complex e. ) Membrane Heterogeneity Complex 28 / 60 How are HLA genes inherited? a. ) Randomly, without parental influence b. ) Only from the mother c. ) Through epigenetic modification d. ) Through both parents e. ) Through mitochondrial DNA 29 / 60 Which of the following antibodies is most commonly found in breast milk, helping protect infants? a. ) IgG b. ) IgM c. ) IgD d. ) IgE e. ) IgA 30 / 60 Which type of cell is involved in killing virus-infected cells directly? a. ) Macrophages b. ) Helper T cells c. ) Neutrophils d. ) Cytotoxic T cells e. ) B cells 31 / 60 What is the function of Class II HLA molecules? a. ) Bind to insulin b. ) Form red blood cells c. ) Regulate blood sugar levels d. ) Present antigens to cytotoxic T cells e. ) Present antigens to helper T cells 32 / 60 What is the primary function of antibodies in adaptive immunity? a. ) Neutralizing toxins and pathogens b. ) Inducing inflammation c. ) Destroying infected cells directly d. ) Activating phagocytes e. ) Generating memory cells 33 / 60 Which of the following is NOT a function of the complement system? a. ) Lysis of pathogens b. ) T cell activation c. ) Opsonization d. ) Inflammation e. ) Phagocytosis of pathogens 34 / 60 What happens if C3 is completely deficient? a. ) Enhanced T-cell activity b. ) Deficient phagocytosis and increased bacterial infections c. ) No effect on immunity d. ) Increased susceptibility to viral infections e. ) Increased cytokine production 35 / 60 Which class of HLA molecules presents antigens to cytotoxic T cells? a. ) Class I b. ) Class IV c. ) Class III d. ) Class II e. ) Class V 36 / 60 What is the characteristic feature of the secondary immune response? a. ) It is stronger and faster than the primary response b. ) It involves only IgM antibodies c. ) It is slower than the primary response d. ) It involves a higher number of neutrophils e. ) It does not involve memory cells 37 / 60 How is the classical complement pathway activated? a. ) Direct recognition of bacteria b. ) Antigen-antibody complex formation c. ) Mannose-binding lectin (MBL) binding d. ) Interaction with T cells e. ) Spontaneous activation on pathogen surfaces 38 / 60 Which of the following is a primary function of macrophages in innate immunity? a. ) Produce cytokines to regulate the immune response b. ) Activate B cells c. ) Produce antibodies d. ) Present antigens and phagocytose pathogens e. ) Present antigens and phagocytose pathogens and Produce cytokines to regulate the immune response 39 / 60 Helper T cells (CD4+) primarily function to: a. ) Help activate other immune cells b. ) Produce insulin c. ) Form blood clots d. ) Secrete digestive enzymes e. ) Directly kill infected cells 40 / 60 Which of the following molecules is involved in the activation of cytotoxic T cells? a. ) IgG b. ) MHC Class I c. ) IgE d. ) Complement proteins e. ) IgM 41 / 60 What does the membrane attack complex (MAC) do? a. ) Leads to the destruction of pathogens b. ) Activates B cells c. ) Produces antibodies d. ) Recruits neutrophils e. ) Stimulates cytokine production 42 / 60 What process allows antibodies to mark pathogens for destruction? a. ) Phagocytosis b. ) Agglutination c. ) Neutralization d. ) Inflammation e. ) Opsonization 43 / 60 Il existe des variations de complΓ©ments, en augmentation ou en diminution selon diverses pathologies, citer une origine de diminution qui est fausse : a. – Inflammation b. – Diminution par consommation excessive de complΓ©ments c. -Diminution par dΓ©faut de synthΓ¨se d. – Diminution par dΓ©perdition 44 / 60 Au cours de la rΓ©ponse naturelle ou innΓ©e, il est apparu lors de la rΓ©action Γ lβinflammation quelques Γ©lΓ©ments, citer lβΓ©lΓ©ment qui est faux : a. -Douleur b. – Chaleur c. – Rougeur d. – ProtΓ©ine dβinflammation e. – PΓ’leur 45 / 60 Les immunoglobulines de surface du lymphocyte B ont un rΓ΄le spΓ©cifique, citer la phrase juste dans: a. -La reconnaissance de lβantigΓ¨ne b. -La dΓ©granulation du basophile c. -Lβactivation de lβhistamine d. -L`activation du polynuclΓ©aire basophile e. -Lβactivation des hΓ©maties 46 / 60 Citer un item qui est faux, pour les activitΓ©s de macrophage ? a. -SynthΓ©tise les chimiokines b. -Ne participe pas la coopΓ©ration cellulaire au cours dβune rΓ©ponse immunitaire c. – Est une cellule prΓ©sentatrice d'antigΓ¨ne d. – Est capable de tuer des bactΓ©ries e. – Est capable dβabsorber les pathogΓ¨nes 47 / 60 Le portages de certain micro-organisme habituellement est commensal chez les cas humains, ces micro-organisme sont devenus virulent chez les malades VIH sΓ©ropositives, citer un micro- organismes connus pour cette propriΓ©tΓ© retrouvΓ©e chez les Cambodgiens: a. Staphylococcus aureus b. Criptosporium spp c. Virus Covid 19 Delta d. Virus Covid 19 e. Virus respiratoire H1N1 48 / 60 Citer lβorgane et fluide biologique suivantes qui nβappartiennent pas Γ la premiΓ¨re ligne de dΓ©fense de lβorganisme : a. – Fluide biologique du systΓ¨me respiratoire b. – Fluide biologique du systΓ¨me digestif c. – Cheveux d. – Salive e. -SystΓ¨me lacrymal 49 / 60 Au cours de la rΓ©ponse immunitaire, citer une phrase qui est juste : a. -La coopΓ©ration cellulaire entre CD4 et CD8 peut aboutir Γ une rΓ©ponse immunitaire non efficace b. -La cellule dendritique est un Γ©lΓ©ment non rΓ©actif Γ lβinterface entre immunitΓ© innΓ©e et adaptative c. – Les hΓ©maties ne peuvent pas sΓ©crΓ©ter des quantitΓ©s importantes de cytokines d. -La rΓ©ponse cellulaire T et B sont deux mΓ©canismes totalement indΓ©pendants e. – Une interaction par coopΓ©ration cellulaire est apparue entre immunitΓ© naturelle et immunitΓ© adaptative 50 / 60 Citer la fonction immunologique de dΓ©fense adaptative qui est fausse: a. – Aide a la mise en place de rΓ©ponse naturelle ou innΓ©e b. – Les lymphocytes B et T assurent la dΓ©fense adaptative c. – RΓ©ponse spΓ©cifique dβantigΓ¨ne d. – Assurer une rΓ©ponse tardive lors dβune primo infection e. -DotΓ©e de mΓ©moire immunologique pour la 2eme agression 51 / 60 Citer la fonction immunologique des interfΓ©rons produits par lymphocytes macrophage et lymphoblastes, citer une phrase qui est fausse : a. – Par dΓ©gradation de lβARN viral b. – Activation des lymphocytes c. – Inhibe la rΓ©plication virale d. – Avoir la propriΓ©tΓ© de participer Γ‘ lβactivation de lβhistamine au cours dβune allergie ; e. -Activation des macrophages 52 / 60 Citer la phrase juste sur la localisation du systΓ¨me HLA ou le systΓ¨me du Complexe Majeur dβHistocompatibilitΓ© (CMH) chez lβhomme est : a. histocompatibilitΓ© CMHI, CMHII, et CMHIII sont localisΓ© dans le chromosome n o 6, sur le bras court du chromosome b. – Parmi les 23 paires de chromosomes humains, les systΓ¨mes de complexe majeur c. – Parmi les 23 paires de chromosomes humains, les systΓ¨mes de complexe majeur d. – les systΓ¨mes de complexe majeur histocompatibilitΓ© CMH1, CMH2, et CMH3 sont localisΓ© e. histocompatibilitΓ© CMH1, CMH2, et CMH3 sont localisΓ© dans le chromosome n o 6 ; f. sur le chromosome n o 6, sur le bras long du chromosome ; g. dans le chromosome n o 6, sur le bras court et long du chromosome ; h. – Parmi les 23 paires de chromosomes humains, les systΓ¨mes de complexe majeur i. histocompatibilitΓ© CMH1, CMH2, et CMH3 sont localisΓ© dans le chromosome n o 5 ; j. -les systΓ¨mes de complexe majeur histocompatibilitΓ© CMH1, CMH2, et CMH3 sont localisΓ© 53 / 60 Citer les caractΓ©ristiques de la fonction immunitaire de lymphocytes CD4, qui est juste : a. -PrΓ©sentatrice de peptides. b. – RΓ©gulation de la rΓ©ponse immune Γ‘ la fois cellulaire et humorale . c. -Pas de mΓ©moire immunologique d. -Reconnaissance de lβantigΓ¨ne spΓ©cifique par le rΓ©cepteur BCR e. – Fonction effectrice. 54 / 60 Citer la dΓ©finition du test de lβELISA (Enzyme linked immuno sorbed assay)? Citer la phrase juste : a. Cβest le test de prΓ©cipitation en gel agarose b. Cβest un test immuno-enzymatique utilisant un appareil de lecture qui dΓ©tecte les antigΓ¨nes ou anticorps pour un antigΓ¨ne ou anticorps spΓ©cifiques c. – Cβest le test de sΓ©rologie Ag-Ac d. – Cβest le test de prΓ©cipitation en milieu agarose. e. – Cβest le test de prΓ©cipitation en milieu liquide. 55 / 60 Le rΓ΄le de lymphocyte CD4 au cours dβune rΓ©ponse immunitaire, citer lβitem qui est juste : a. – RΓ΄le de rΓ©gulation au cours dβune rΓ©ponse Γ la fois cellulaire et humorale ; b. – RΓ΄le dβΓ©liminer les corps Γ©trangers par sΓ©crΓ©tion des chimiokines c. – RΓ΄le cytotoxique (CTL) cΓ d il sΓ©crΓ¨te une substance capable de lyser les organismes Γ©trangers ; d. – RΓ΄le de rΓ©gulation au cours dβune rΓ©ponse naturelle e. – RΓ΄le de prΓ©sentatrice de lβantigΓ¨ne aux autres cellules du systΓ¨me immunitaire. 56 / 60 La dΓ©finition de lβimmunochimie ? Citer la phrase juste a. Cβest lβensemble des techniques qualitatives et quantitatives de dosage des molΓ©cules du systΓ¨me immunitaires b. – Cβest lβensemble des techniques qualitatives et quantitatives de dosage de molΓ©cules, cellules, antigΓ¨nes et des anticorps du systΓ¨me immunitaire c. – Cβest lβensemble des techniques de dosage des Γ©pitopes antigΓ©niques d. – Cβest lβensemble de techniques de dosage seulement des antigΓ¨nes viraux e. – Cβest lβensemble des techniques qualitatives de dΓ©pistage des gΓ¨nes viraux et bactΓ©riens ; 57 / 60 Nature chimique dβun antigΓ¨ne ? Citer une phrase qui est fausse ? a. – ProtΓ©ine. b. -Polypeptides c. – Acide lactique d. – Polysaccharides e. -Acide aminΓ© 58 / 60 Citer une phrase qui est fausse, les organes-et tissu composants du tissu lymphoΓ―des secondaire sont : a. – Tissu lymphoΓ―de pulmonaire diffus. b. -Thymus et moelle osseuse ; c. – Plaque de Peyer d. – Cellules Langherans de la peau e. – Ganglions lymphatiques 59 / 60 Au cours de cycles de rΓ©plication des virus VIH, quelques Γ©tapes se reproduits essentiellement, citer une Γ©tape qui est fausse : a. -Etape de production ADN proviral en ARN gΓ©nomique et ARN messager grΓ ce Γ lβenzyme lβintΓ©grase b. -Etapes de synthΓ¨se dβADN viral double brins Γ partir dβARN simple brin du virus, cet Γ©vΓ¨nement est possible grΓ’ce Γ lβactivitΓ© de polymΓ©rase et Rnase de lβenzymes de la transcriptase inverse c. -Etape de destruction de protΓ©ines de structure des virus. d. Etapes dβattachement se faisant a partir de glycoprotΓ©ine membranaire gp120 du virus avec les protΓ©ines membranaires CD4 de lymphocytes CD4 e. – Etapes de reconnaissances 60 / 60 Quel est le mode dβabsorbation de virus Covid 19 par les Γͺtres humains ? a. -Soigner les malades muni de prΓ©cautions ( port de gant, masque etcβ¦.) b. -Via lβaΓ©rosol par voie respiratoire c. -Tenir la main avec une personne non positives par Covid 19 d. -Fait le sport ensemble avec dβautres personnes non Covid e. -Manger ensemble avec dβautres personnes non positives par Covid 19 Your score isThe average score is 0% Facebook 0% Restart quiz Any comments? Send feedback
