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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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2)

The characteristic of antigen-antibody interactions occur in primary stage:

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3)

The complement system involved in the inflammation are:

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4)

The following statements are criteria for a good vaccine but which is incorrect statement?

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5)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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6)

Injection of immunoglobulin is:

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7)

The classical pathway of complement activation is:

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8)

Which of the following is a polysaccharide vaccine:

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9)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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10)

Which of the following is not an ideal property of a vaccine?

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11)

All are functions of immunoglobulins but except:

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12)

Tetanus toxoid is usually given to humans:

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13)

Which of the following statements are true regarding polio vaccines:

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14)

The main advantage of passive immunization over active immunization is that:

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15)

All are examples of names of monoclonal antibodies but except one?

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16)

The Follicular Dendritic Cells (FDCs) is located in:

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17)

In order to elicit an immune response, a carbohydrate must be which of the following?

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18)

Infectious material from what illness was used to develop the first vaccine?

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19)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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20)

The adverse effects of vaccines are linked to:

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21)

The following statements are the use of passive immunization included but except one?

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22)

An antigen is:

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23)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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24)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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25)

All the given vaccines are attenuated or inactivated whole pathogen except:

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26)

Successful immunization can be impaired by:

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27)

The complement system consists of about:

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28)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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29)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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30)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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31)

Graft and tumor rejection are mediated primarily by:

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32)

The complement system involved in phagocytic function are:

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33)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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34)

Which of the following is not the function of antibody?

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35)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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36)

The purpose of clinical trial of a vaccine is:

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37)

In an immune response the type of cell which gets activated earliest is:

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38)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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39)

The immune cells that is linked between innate and adaptive immunity are:

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40)

What is the mode of administration for anti-measles vaccine?

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41)

Which of the following statement is true regarding vaccination:

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42)

The complement system involved in chemotaxis are:

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43)

What vaccine should be avoided for the pregnant woman?

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44)

Primary lymphoid organs include

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45)

An epitope is:

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46)

The naive T cells are:

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47)

The Adverse events following immunization (AEFI) are divided into:

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48)

The role of the macrophage during an antibody response is to:

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49)

All are therapeutic applications of polyclonal antibodies but except one?

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50)

The class II MHC molecule appeared to bind with receptor of:

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51)

The first recombinant antigen vaccine approved for human use is:

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52)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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53)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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54)

All are important characteristics of innate immunity but except:

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55)

The class I MHC molecule appeared to bind with receptor of:

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56)

All are the measure for post rabies exposure prophylaxis, but except one?

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57)

Which antibody is the first to be released into the blood following an infection?

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58)

Adjuvant used in HPV vaccine is:

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59)

Newborns get their antibodies from mother’s milk. This is an example of?

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60)

The immunoglobulins participated in complement system formation are:

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61)

The immunoglobulins transport across placenta mostly:

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The immunoglobulins transport across epithelium:

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63)

Serum which contains antibodies is called:

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64)

Several of the complement components are:

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65)

All the following comes under non-specific defence mechanism except

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66)

Small chemical groups on the antigen molecule that can react with antibody

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67)

The impact is:

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68)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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69)

What is the mode of administration for PCV-13 vaccine?

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70)

The immune cells that is linked between innate and adaptive immunity are:

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71)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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72)

All are immune cells in innate immune system but except:

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73)

The general principle of vaccination was established by:

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74)

What is a live attenuated vaccine?

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75)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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76)

In the application Antigen- Antibody reaction, which one is correct?

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77)

The complement system are synthesized by:

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78)

In the application Antigen- Antibody reaction, which one is correct?

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79)

Injection of anti-venom to a patient for snake bite is example of?

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80)

All are factors influencing in immunogenicity but except:

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81)

The bonds involved in antigen-antibody interactions are

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82)

Which of the following statement is true

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83)

The process of weakening a pathogen is called:

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84)

Which of the following antibodies have a positive effect on babies through breast feeding?

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85)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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86)

The type of T-cells that destroy host cells bearing foreign antigen:

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87)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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88)

All are 3 main effects of complement but except:

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89)

What is the mode of administration for BCG vaccine?

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90)

The circulation of a two month old breast-fed baby will contain maternal:

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91)

What vaccine should not be frozen:

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92)

The cytotoxic T-cells is involved in:

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93)

The herd immunity is:

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94)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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95)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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96)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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97)

What is the immune cell in adaptive immunity?

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98)

The antibody-binding site is formed primarily by:

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99)

The technology used for the production of monoclonal antibodies is:

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100)

In the application Antigen- Antibody reaction, which one is correct?

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101)

Which of the following is the site of T cell maturation?

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102)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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103)

Adjuvant used in HBV vaccine is:

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104)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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105)

Antigen presenting cells for vaccine are:

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106)

The classical pathway of complement activation is:

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107)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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108)

The effectiveness is:

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109)

In the application Antigen- Antibody reaction, which one is not correct?

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110)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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111)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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112)

An epitope:

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113)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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114)

Vaccination is an example of?

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115)

What vaccine can be used for pregnant women?

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116)

An immunoglobulin is a:

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117)

All are mechanism of action of complement but except:

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118)

All are Antigen-Presenting Cells (APCs) but except:

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119)

The first line of defense against invading pathogens:

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120)

Natural humoral immune response against a pathogen leads to the production of:

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121)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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122)

The efficacy is:

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123)

Mode of IPV vaccine administration is:

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124)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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125)

The antigen-antibody interactions occur in:

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126)

The characteristic of antigen-antibody interactions occur in second stage:

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127)

Immunogen is:

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128)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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129)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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130)

Which of the following antibody types forms a pentamer?

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