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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Which of the following antibodies have a positive effect on babies through breast feeding?

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2)

The Adverse events following immunization (AEFI) are divided into:

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3)

The antigen-antibody interactions occur in:

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4)

Adjuvant used in HPV vaccine is:

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5)

All are Antigen-Presenting Cells (APCs) but except:

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6)

The complement system involved in phagocytic function are:

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7)

The bonds involved in antigen-antibody interactions are

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8)

The following statements are criteria for a good vaccine but which is incorrect statement?

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9)

The immunoglobulins transport across epithelium:

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10)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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11)

What is the mode of administration for anti-measles vaccine?

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12)

All are examples of names of monoclonal antibodies but except one?

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13)

The efficacy is:

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14)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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15)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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16)

The following statements are the use of passive immunization included but except one?

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17)

Mode of IPV vaccine administration is:

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18)

The Follicular Dendritic Cells (FDCs) is located in:

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19)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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20)

The technology used for the production of monoclonal antibodies is:

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21)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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22)

All are the measure for post rabies exposure prophylaxis, but except one?

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23)

In an immune response the type of cell which gets activated earliest is:

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24)

In the application Antigen- Antibody reaction, which one is correct?

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25)

The complement system involved in chemotaxis are:

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26)

Several of the complement components are:

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27)

What is the mode of administration for BCG vaccine?

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28)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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29)

The classical pathway of complement activation is:

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30)

Successful immunization can be impaired by:

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31)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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32)

What vaccine should be avoided for the pregnant woman?

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33)

The first recombinant antigen vaccine approved for human use is:

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34)

All are 3 main effects of complement but except:

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35)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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36)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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37)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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38)

Immunogen is:

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39)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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40)

Adjuvant used in HBV vaccine is:

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41)

The main advantage of passive immunization over active immunization is that:

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42)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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43)

What is a live attenuated vaccine?

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44)

In order to elicit an immune response, a carbohydrate must be which of the following?

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45)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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46)

Antigen presenting cells for vaccine are:

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47)

Small chemical groups on the antigen molecule that can react with antibody

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48)

Vaccination is an example of?

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49)

Serum which contains antibodies is called:

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50)

The first line of defense against invading pathogens:

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51)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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52)

An epitope is:

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53)

The immune cells that is linked between innate and adaptive immunity are:

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54)

Which of the following statement is true regarding vaccination:

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55)

The immune cells that is linked between innate and adaptive immunity are:

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56)

In the application Antigen- Antibody reaction, which one is correct?

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57)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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58)

The antibody-binding site is formed primarily by:

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59)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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60)

The process of weakening a pathogen is called:

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61)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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62)

All are therapeutic applications of polyclonal antibodies but except one?

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63)

The herd immunity is:

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64)

The immunoglobulins transport across placenta mostly:

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65)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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66)

The class I MHC molecule appeared to bind with receptor of:

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67)

The complement system are synthesized by:

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68)

What vaccine should not be frozen:

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69)

The type of T-cells that destroy host cells bearing foreign antigen:

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70)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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71)

Infectious material from what illness was used to develop the first vaccine?

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72)

All the given vaccines are attenuated or inactivated whole pathogen except:

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73)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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74)

All are immune cells in innate immune system but except:

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75)

All are important characteristics of innate immunity but except:

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76)

The classical pathway of complement activation is:

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77)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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78)

All are mechanism of action of complement but except:

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79)

Tetanus toxoid is usually given to humans:

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80)

An immunoglobulin is a:

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81)

The adverse effects of vaccines are linked to:

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82)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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83)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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84)

The naive T cells are:

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85)

Which of the following antibody types forms a pentamer?

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86)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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87)

The characteristic of antigen-antibody interactions occur in primary stage:

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88)

Which of the following is a polysaccharide vaccine:

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89)

In the application Antigen- Antibody reaction, which one is not correct?

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90)

What vaccine can be used for pregnant women?

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91)

Injection of immunoglobulin is:

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92)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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93)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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94)

Which of the following is the site of T cell maturation?

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95)

An epitope:

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96)

All are functions of immunoglobulins but except:

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97)

The impact is:

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98)

The effectiveness is:

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99)

Which antibody is the first to be released into the blood following an infection?

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100)

What is the mode of administration for PCV-13 vaccine?

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101)

An antigen is:

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102)

Graft and tumor rejection are mediated primarily by:

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103)

The complement system involved in the inflammation are:

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104)

The characteristic of antigen-antibody interactions occur in second stage:

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105)

The complement system consists of about:

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106)

The purpose of clinical trial of a vaccine is:

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107)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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108)

What is the immune cell in adaptive immunity?

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109)

In the application Antigen- Antibody reaction, which one is correct?

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110)

The immunoglobulins participated in complement system formation are:

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111)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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112)

Primary lymphoid organs include

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113)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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114)

The general principle of vaccination was established by:

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115)

Natural humoral immune response against a pathogen leads to the production of:

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116)

Which of the following is not an ideal property of a vaccine?

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117)

The role of the macrophage during an antibody response is to:

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118)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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119)

All the following comes under non-specific defence mechanism except

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120)

The cytotoxic T-cells is involved in:

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121)

Which of the following is not the function of antibody?

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122)

Which of the following statements are true regarding polio vaccines:

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123)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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124)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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125)

All are factors influencing in immunogenicity but except:

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126)

Newborns get their antibodies from mother’s milk. This is an example of?

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127)

Injection of anti-venom to a patient for snake bite is example of?

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128)

The class II MHC molecule appeared to bind with receptor of:

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129)

Which of the following statement is true

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130)

The circulation of a two month old breast-fed baby will contain maternal:

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