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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

All are mechanism of action of complement but except:

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2)

Primary lymphoid organs include

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3)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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4)

The complement system involved in chemotaxis are:

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5)

What is the mode of administration for PCV-13 vaccine?

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6)

The impact is:

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7)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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8)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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9)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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10)

Which of the following is a polysaccharide vaccine:

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11)

The technology used for the production of monoclonal antibodies is:

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12)

The cytotoxic T-cells is involved in:

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13)

An epitope is:

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14)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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15)

The naive T cells are:

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16)

All the following comes under non-specific defence mechanism except

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17)

What is the immune cell in adaptive immunity?

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18)

All are functions of immunoglobulins but except:

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19)

The herd immunity is:

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20)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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21)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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22)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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23)

All are Antigen-Presenting Cells (APCs) but except:

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24)

All are therapeutic applications of polyclonal antibodies but except one?

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25)

Adjuvant used in HBV vaccine is:

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26)

All are immune cells in innate immune system but except:

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27)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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28)

Which of the following statements are true regarding polio vaccines:

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29)

The immune cells that is linked between innate and adaptive immunity are:

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30)

The immunoglobulins transport across epithelium:

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31)

The complement system involved in phagocytic function are:

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32)

The antibody-binding site is formed primarily by:

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33)

Vaccination is an example of?

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34)

Which of the following is not an ideal property of a vaccine?

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35)

Which antibody is the first to be released into the blood following an infection?

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36)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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37)

The characteristic of antigen-antibody interactions occur in primary stage:

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38)

The immune cells that is linked between innate and adaptive immunity are:

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39)

Antigen presenting cells for vaccine are:

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40)

The adverse effects of vaccines are linked to:

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41)

The Adverse events following immunization (AEFI) are divided into:

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42)

What is the mode of administration for BCG vaccine?

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43)

What vaccine can be used for pregnant women?

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44)

An epitope:

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45)

The following statements are the use of passive immunization included but except one?

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46)

Tetanus toxoid is usually given to humans:

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47)

The complement system involved in the inflammation are:

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48)

The class II MHC molecule appeared to bind with receptor of:

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49)

In an immune response the type of cell which gets activated earliest is:

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50)

Graft and tumor rejection are mediated primarily by:

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51)

The class I MHC molecule appeared to bind with receptor of:

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52)

All are factors influencing in immunogenicity but except:

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53)

The bonds involved in antigen-antibody interactions are

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54)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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55)

Serum which contains antibodies is called:

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56)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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57)

The type of T-cells that destroy host cells bearing foreign antigen:

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58)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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59)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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60)

Adjuvant used in HPV vaccine is:

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61)

The role of the macrophage during an antibody response is to:

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62)

The general principle of vaccination was established by:

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63)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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64)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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65)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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66)

Several of the complement components are:

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67)

The first line of defense against invading pathogens:

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68)

The following statements are criteria for a good vaccine but which is incorrect statement?

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69)

The antigen-antibody interactions occur in:

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70)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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71)

All the given vaccines are attenuated or inactivated whole pathogen except:

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72)

The complement system consists of about:

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73)

Which of the following is not the function of antibody?

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74)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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75)

Newborns get their antibodies from mother’s milk. This is an example of?

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76)

What vaccine should not be frozen:

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77)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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78)

Which of the following is the site of T cell maturation?

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79)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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80)

All are 3 main effects of complement but except:

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81)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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82)

The efficacy is:

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83)

All are important characteristics of innate immunity but except:

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84)

The circulation of a two month old breast-fed baby will contain maternal:

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85)

The purpose of clinical trial of a vaccine is:

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86)

The process of weakening a pathogen is called:

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87)

In order to elicit an immune response, a carbohydrate must be which of the following?

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88)

The Follicular Dendritic Cells (FDCs) is located in:

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89)

The effectiveness is:

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90)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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91)

All are the measure for post rabies exposure prophylaxis, but except one?

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92)

Injection of anti-venom to a patient for snake bite is example of?

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93)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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94)

The complement system are synthesized by:

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95)

What is a live attenuated vaccine?

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96)

The main advantage of passive immunization over active immunization is that:

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97)

An antigen is:

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98)

In the application Antigen- Antibody reaction, which one is not correct?

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99)

Natural humoral immune response against a pathogen leads to the production of:

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100)

What is the mode of administration for anti-measles vaccine?

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101)

In the application Antigen- Antibody reaction, which one is correct?

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102)

In the application Antigen- Antibody reaction, which one is correct?

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103)

The immunoglobulins transport across placenta mostly:

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104)

The immunoglobulins participated in complement system formation are:

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105)

The characteristic of antigen-antibody interactions occur in second stage:

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106)

Immunogen is:

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107)

The first recombinant antigen vaccine approved for human use is:

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108)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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109)

All are examples of names of monoclonal antibodies but except one?

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110)

Infectious material from what illness was used to develop the first vaccine?

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111)

Mode of IPV vaccine administration is:

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112)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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113)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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114)

The classical pathway of complement activation is:

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115)

Which of the following antibody types forms a pentamer?

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116)

An immunoglobulin is a:

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117)

Which of the following statement is true regarding vaccination:

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118)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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119)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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120)

Which of the following antibodies have a positive effect on babies through breast feeding?

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121)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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122)

Injection of immunoglobulin is:

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123)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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124)

Small chemical groups on the antigen molecule that can react with antibody

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125)

Successful immunization can be impaired by:

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126)

What vaccine should be avoided for the pregnant woman?

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127)

Which of the following statement is true

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128)

The classical pathway of complement activation is:

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129)

In the application Antigen- Antibody reaction, which one is correct?

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130)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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