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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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2)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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3)

The circulation of a two month old breast-fed baby will contain maternal:

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4)

The antigen-antibody interactions occur in:

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5)

Which of the following is not the function of antibody?

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6)

Small chemical groups on the antigen molecule that can react with antibody

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7)

The role of the macrophage during an antibody response is to:

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8)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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9)

What is the mode of administration for PCV-13 vaccine?

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10)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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11)

All are Antigen-Presenting Cells (APCs) but except:

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12)

All the following comes under non-specific defence mechanism except

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13)

The antibody-binding site is formed primarily by:

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14)

The cytotoxic T-cells is involved in:

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15)

Primary lymphoid organs include

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16)

The first recombinant antigen vaccine approved for human use is:

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17)

The Adverse events following immunization (AEFI) are divided into:

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18)

The immune cells that is linked between innate and adaptive immunity are:

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19)

Serum which contains antibodies is called:

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20)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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21)

The immunoglobulins participated in complement system formation are:

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22)

Which of the following is the site of T cell maturation?

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23)

Injection of anti-venom to a patient for snake bite is example of?

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24)

Vaccination is an example of?

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25)

An epitope is:

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26)

All are immune cells in innate immune system but except:

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27)

What is the mode of administration for BCG vaccine?

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28)

The following statements are criteria for a good vaccine but which is incorrect statement?

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29)

The immunoglobulins transport across epithelium:

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30)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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31)

The complement system consists of about:

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32)

Newborns get their antibodies from mother’s milk. This is an example of?

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33)

The process of weakening a pathogen is called:

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34)

All the given vaccines are attenuated or inactivated whole pathogen except:

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35)

Which of the following antibodies have a positive effect on babies through breast feeding?

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36)

Injection of immunoglobulin is:

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37)

The characteristic of antigen-antibody interactions occur in second stage:

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38)

The efficacy is:

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39)

Which of the following is not an ideal property of a vaccine?

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40)

The complement system involved in chemotaxis are:

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41)

In the application Antigen- Antibody reaction, which one is not correct?

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42)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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43)

What vaccine can be used for pregnant women?

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44)

Tetanus toxoid is usually given to humans:

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45)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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46)

What vaccine should not be frozen:

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47)

The herd immunity is:

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48)

All are examples of names of monoclonal antibodies but except one?

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49)

The class II MHC molecule appeared to bind with receptor of:

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50)

The adverse effects of vaccines are linked to:

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51)

All are mechanism of action of complement but except:

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52)

The following statements are the use of passive immunization included but except one?

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53)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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54)

The class I MHC molecule appeared to bind with receptor of:

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55)

Infectious material from what illness was used to develop the first vaccine?

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56)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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57)

The impact is:

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58)

Adjuvant used in HBV vaccine is:

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59)

The immune cells that is linked between innate and adaptive immunity are:

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60)

Immunogen is:

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61)

All are therapeutic applications of polyclonal antibodies but except one?

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62)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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63)

Several of the complement components are:

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64)

In the application Antigen- Antibody reaction, which one is correct?

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65)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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66)

The technology used for the production of monoclonal antibodies is:

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67)

Successful immunization can be impaired by:

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68)

Graft and tumor rejection are mediated primarily by:

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69)

What is the immune cell in adaptive immunity?

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70)

Which of the following is a polysaccharide vaccine:

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71)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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72)

All are the measure for post rabies exposure prophylaxis, but except one?

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73)

All are functions of immunoglobulins but except:

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74)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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75)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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76)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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77)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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78)

In order to elicit an immune response, a carbohydrate must be which of the following?

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79)

The complement system are synthesized by:

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80)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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81)

In the application Antigen- Antibody reaction, which one is correct?

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82)

The naive T cells are:

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83)

The type of T-cells that destroy host cells bearing foreign antigen:

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84)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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85)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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86)

The general principle of vaccination was established by:

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87)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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88)

The complement system involved in phagocytic function are:

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89)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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90)

The effectiveness is:

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91)

The immunoglobulins transport across placenta mostly:

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92)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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93)

The complement system involved in the inflammation are:

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94)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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95)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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96)

Adjuvant used in HPV vaccine is:

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97)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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98)

What vaccine should be avoided for the pregnant woman?

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99)

Antigen presenting cells for vaccine are:

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100)

The Follicular Dendritic Cells (FDCs) is located in:

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101)

The classical pathway of complement activation is:

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102)

An immunoglobulin is a:

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103)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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104)

All are important characteristics of innate immunity but except:

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105)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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106)

An epitope:

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107)

All are factors influencing in immunogenicity but except:

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108)

Which of the following statement is true

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109)

What is a live attenuated vaccine?

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110)

Which of the following statements are true regarding polio vaccines:

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111)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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112)

What is the mode of administration for anti-measles vaccine?

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113)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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114)

In the application Antigen- Antibody reaction, which one is correct?

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115)

Which of the following statement is true regarding vaccination:

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116)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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117)

The bonds involved in antigen-antibody interactions are

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118)

In an immune response the type of cell which gets activated earliest is:

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119)

The classical pathway of complement activation is:

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120)

Which of the following antibody types forms a pentamer?

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121)

Which antibody is the first to be released into the blood following an infection?

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122)

The first line of defense against invading pathogens:

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123)

The purpose of clinical trial of a vaccine is:

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124)

All are 3 main effects of complement but except:

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125)

An antigen is:

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126)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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127)

The main advantage of passive immunization over active immunization is that:

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128)

Natural humoral immune response against a pathogen leads to the production of:

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129)

Mode of IPV vaccine administration is:

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130)

The characteristic of antigen-antibody interactions occur in primary stage:

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