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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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2)

All are factors influencing in immunogenicity but except:

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3)

The immune cells that is linked between innate and adaptive immunity are:

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4)

Mode of IPV vaccine administration is:

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5)

The first line of defense against invading pathogens:

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6)

An antigen is:

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7)

The immunoglobulins transport across placenta mostly:

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8)

The bonds involved in antigen-antibody interactions are

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9)

Successful immunization can be impaired by:

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10)

Natural humoral immune response against a pathogen leads to the production of:

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11)

All are therapeutic applications of polyclonal antibodies but except one?

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12)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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13)

All are examples of names of monoclonal antibodies but except one?

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14)

Which of the following is the site of T cell maturation?

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15)

What is the mode of administration for PCV-13 vaccine?

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16)

The complement system are synthesized by:

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17)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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18)

Vaccination is an example of?

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19)

An immunoglobulin is a:

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20)

Serum which contains antibodies is called:

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21)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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22)

Primary lymphoid organs include

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23)

The technology used for the production of monoclonal antibodies is:

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24)

The process of weakening a pathogen is called:

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25)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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26)

Which of the following statements are true regarding polio vaccines:

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27)

Several of the complement components are:

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28)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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29)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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30)

All are important characteristics of innate immunity but except:

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31)

What vaccine should not be frozen:

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32)

Immunogen is:

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33)

The purpose of clinical trial of a vaccine is:

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34)

All are mechanism of action of complement but except:

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35)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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36)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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37)

Newborns get their antibodies from mother’s milk. This is an example of?

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38)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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39)

The herd immunity is:

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40)

The immunoglobulins transport across epithelium:

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41)

The characteristic of antigen-antibody interactions occur in primary stage:

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42)

An epitope:

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43)

Infectious material from what illness was used to develop the first vaccine?

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44)

Tetanus toxoid is usually given to humans:

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45)

What is the immune cell in adaptive immunity?

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46)

The characteristic of antigen-antibody interactions occur in second stage:

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47)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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48)

In the application Antigen- Antibody reaction, which one is correct?

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49)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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50)

The circulation of a two month old breast-fed baby will contain maternal:

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51)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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52)

Injection of immunoglobulin is:

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53)

The main advantage of passive immunization over active immunization is that:

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54)

The classical pathway of complement activation is:

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55)

All the following comes under non-specific defence mechanism except

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56)

Adjuvant used in HBV vaccine is:

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57)

The complement system involved in chemotaxis are:

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58)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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59)

All the given vaccines are attenuated or inactivated whole pathogen except:

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60)

The efficacy is:

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61)

The first recombinant antigen vaccine approved for human use is:

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62)

The class II MHC molecule appeared to bind with receptor of:

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63)

Which of the following antibodies have a positive effect on babies through breast feeding?

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64)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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65)

The classical pathway of complement activation is:

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66)

The Adverse events following immunization (AEFI) are divided into:

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67)

The antigen-antibody interactions occur in:

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68)

All are immune cells in innate immune system but except:

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69)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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70)

What is the mode of administration for anti-measles vaccine?

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71)

All are functions of immunoglobulins but except:

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72)

The type of T-cells that destroy host cells bearing foreign antigen:

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73)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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74)

Which of the following is a polysaccharide vaccine:

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75)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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76)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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77)

What vaccine can be used for pregnant women?

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78)

In the application Antigen- Antibody reaction, which one is not correct?

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79)

Which of the following antibody types forms a pentamer?

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80)

The complement system involved in phagocytic function are:

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81)

In order to elicit an immune response, a carbohydrate must be which of the following?

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82)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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83)

Antigen presenting cells for vaccine are:

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84)

Graft and tumor rejection are mediated primarily by:

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85)

The immunoglobulins participated in complement system formation are:

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86)

The following statements are criteria for a good vaccine but which is incorrect statement?

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87)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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The adverse effects of vaccines are linked to:

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89)

The class I MHC molecule appeared to bind with receptor of:

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90)

The general principle of vaccination was established by:

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91)

Which of the following statement is true

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92)

What is a live attenuated vaccine?

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93)

Injection of anti-venom to a patient for snake bite is example of?

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94)

Adjuvant used in HPV vaccine is:

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95)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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96)

All are 3 main effects of complement but except:

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97)

The complement system involved in the inflammation are:

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98)

The role of the macrophage during an antibody response is to:

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99)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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100)

The Follicular Dendritic Cells (FDCs) is located in:

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101)

The naive T cells are:

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102)

The antibody-binding site is formed primarily by:

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103)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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104)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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105)

Which of the following statement is true regarding vaccination:

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106)

Which of the following is not the function of antibody?

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107)

All are the measure for post rabies exposure prophylaxis, but except one?

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108)

In an immune response the type of cell which gets activated earliest is:

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109)

The cytotoxic T-cells is involved in:

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110)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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111)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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112)

What vaccine should be avoided for the pregnant woman?

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113)

Which antibody is the first to be released into the blood following an infection?

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114)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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115)

The following statements are the use of passive immunization included but except one?

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116)

The complement system consists of about:

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117)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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118)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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119)

Which of the following is not an ideal property of a vaccine?

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120)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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121)

The effectiveness is:

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122)

What is the mode of administration for BCG vaccine?

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123)

The impact is:

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124)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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125)

All are Antigen-Presenting Cells (APCs) but except:

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126)

The immune cells that is linked between innate and adaptive immunity are:

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127)

In the application Antigen- Antibody reaction, which one is correct?

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128)

In the application Antigen- Antibody reaction, which one is correct?

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An epitope is:

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Small chemical groups on the antigen molecule that can react with antibody

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