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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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2)

What is the immune cell in adaptive immunity?

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3)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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4)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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5)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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6)

The complement system involved in chemotaxis are:

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7)

The complement system involved in phagocytic function are:

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8)

The immunoglobulins transport across epithelium:

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9)

Newborns get their antibodies from mother’s milk. This is an example of?

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10)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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11)

The classical pathway of complement activation is:

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12)

Graft and tumor rejection are mediated primarily by:

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13)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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14)

The Adverse events following immunization (AEFI) are divided into:

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15)

The immunoglobulins participated in complement system formation are:

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16)

Mode of IPV vaccine administration is:

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17)

The first line of defense against invading pathogens:

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18)

In the application Antigen- Antibody reaction, which one is correct?

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19)

An epitope is:

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20)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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21)

The process of weakening a pathogen is called:

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22)

All the following comes under non-specific defence mechanism except

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23)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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24)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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25)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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26)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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27)

In the application Antigen- Antibody reaction, which one is correct?

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28)

The technology used for the production of monoclonal antibodies is:

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29)

An antigen is:

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30)

The complement system are synthesized by:

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31)

What is a live attenuated vaccine?

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32)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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33)

Successful immunization can be impaired by:

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34)

The Follicular Dendritic Cells (FDCs) is located in:

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35)

Primary lymphoid organs include

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36)

All are mechanism of action of complement but except:

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37)

All are immune cells in innate immune system but except:

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38)

Several of the complement components are:

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39)

Natural humoral immune response against a pathogen leads to the production of:

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40)

All are the measure for post rabies exposure prophylaxis, but except one?

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41)

The immunoglobulins transport across placenta mostly:

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42)

The effectiveness is:

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43)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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44)

In the application Antigen- Antibody reaction, which one is not correct?

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45)

The naive T cells are:

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46)

All the given vaccines are attenuated or inactivated whole pathogen except:

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47)

What vaccine should be avoided for the pregnant woman?

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48)

The following statements are criteria for a good vaccine but which is incorrect statement?

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49)

Antigen presenting cells for vaccine are:

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50)

An immunoglobulin is a:

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51)

What is the mode of administration for BCG vaccine?

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52)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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53)

Small chemical groups on the antigen molecule that can react with antibody

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54)

The cytotoxic T-cells is involved in:

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55)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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56)

The characteristic of antigen-antibody interactions occur in second stage:

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57)

Vaccination is an example of?

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58)

The circulation of a two month old breast-fed baby will contain maternal:

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59)

All are functions of immunoglobulins but except:

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60)

Which of the following is a polysaccharide vaccine:

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61)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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62)

Adjuvant used in HBV vaccine is:

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63)

What vaccine should not be frozen:

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64)

All are 3 main effects of complement but except:

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65)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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66)

Serum which contains antibodies is called:

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67)

The antibody-binding site is formed primarily by:

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68)

The bonds involved in antigen-antibody interactions are

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69)

In order to elicit an immune response, a carbohydrate must be which of the following?

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70)

Which antibody is the first to be released into the blood following an infection?

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71)

Which of the following statement is true

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72)

Which of the following statements are true regarding polio vaccines:

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73)

The purpose of clinical trial of a vaccine is:

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74)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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75)

Which of the following is not an ideal property of a vaccine?

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76)

The class II MHC molecule appeared to bind with receptor of:

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77)

The classical pathway of complement activation is:

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78)

Which of the following statement is true regarding vaccination:

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79)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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80)

Adjuvant used in HPV vaccine is:

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81)

The type of T-cells that destroy host cells bearing foreign antigen:

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82)

The antigen-antibody interactions occur in:

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83)

Tetanus toxoid is usually given to humans:

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84)

Which of the following is not the function of antibody?

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85)

The following statements are the use of passive immunization included but except one?

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86)

In the application Antigen- Antibody reaction, which one is correct?

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87)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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88)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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89)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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90)

The herd immunity is:

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91)

The immune cells that is linked between innate and adaptive immunity are:

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92)

The complement system consists of about:

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93)

Injection of anti-venom to a patient for snake bite is example of?

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94)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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95)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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96)

What is the mode of administration for PCV-13 vaccine?

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97)

The impact is:

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98)

In an immune response the type of cell which gets activated earliest is:

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99)

An epitope:

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100)

The first recombinant antigen vaccine approved for human use is:

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101)

What is the mode of administration for anti-measles vaccine?

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102)

The immune cells that is linked between innate and adaptive immunity are:

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103)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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104)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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105)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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106)

Immunogen is:

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107)

The role of the macrophage during an antibody response is to:

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108)

All are Antigen-Presenting Cells (APCs) but except:

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109)

All are important characteristics of innate immunity but except:

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110)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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111)

The efficacy is:

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112)

Infectious material from what illness was used to develop the first vaccine?

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113)

All are examples of names of monoclonal antibodies but except one?

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114)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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115)

All are factors influencing in immunogenicity but except:

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116)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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117)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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118)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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119)

Injection of immunoglobulin is:

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120)

All are therapeutic applications of polyclonal antibodies but except one?

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121)

Which of the following is the site of T cell maturation?

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122)

The main advantage of passive immunization over active immunization is that:

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123)

The adverse effects of vaccines are linked to:

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124)

The class I MHC molecule appeared to bind with receptor of:

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125)

Which of the following antibodies have a positive effect on babies through breast feeding?

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126)

Which of the following antibody types forms a pentamer?

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127)

The general principle of vaccination was established by:

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128)

What vaccine can be used for pregnant women?

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129)

The characteristic of antigen-antibody interactions occur in primary stage:

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130)

The complement system involved in the inflammation are:

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