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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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2)

All are Antigen-Presenting Cells (APCs) but except:

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3)

The characteristic of antigen-antibody interactions occur in primary stage:

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4)

What is the mode of administration for BCG vaccine?

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5)

Which of the following antibodies have a positive effect on babies through breast feeding?

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6)

The complement system are synthesized by:

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7)

Infectious material from what illness was used to develop the first vaccine?

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8)

The process of weakening a pathogen is called:

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9)

The classical pathway of complement activation is:

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10)

Which of the following is not an ideal property of a vaccine?

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11)

The bonds involved in antigen-antibody interactions are

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12)

The first line of defense against invading pathogens:

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13)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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14)

Serum which contains antibodies is called:

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15)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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16)

The Follicular Dendritic Cells (FDCs) is located in:

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17)

An epitope:

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18)

Adjuvant used in HBV vaccine is:

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19)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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20)

The immunoglobulins transport across epithelium:

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21)

Which of the following is not the function of antibody?

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22)

All the following comes under non-specific defence mechanism except

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23)

The impact is:

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24)

Tetanus toxoid is usually given to humans:

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25)

Injection of anti-venom to a patient for snake bite is example of?

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26)

In the application Antigen- Antibody reaction, which one is not correct?

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27)

The class II MHC molecule appeared to bind with receptor of:

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28)

The naive T cells are:

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29)

What is the mode of administration for anti-measles vaccine?

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30)

The first recombinant antigen vaccine approved for human use is:

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31)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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32)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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33)

All are important characteristics of innate immunity but except:

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34)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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35)

The complement system consists of about:

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36)

What vaccine can be used for pregnant women?

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37)

Several of the complement components are:

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38)

An epitope is:

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39)

Which of the following statement is true regarding vaccination:

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40)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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41)

Newborns get their antibodies from mother’s milk. This is an example of?

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42)

An immunoglobulin is a:

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43)

What vaccine should be avoided for the pregnant woman?

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44)

Primary lymphoid organs include

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45)

All are factors influencing in immunogenicity but except:

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46)

Which of the following is a polysaccharide vaccine:

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47)

The circulation of a two month old breast-fed baby will contain maternal:

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48)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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49)

All are examples of names of monoclonal antibodies but except one?

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50)

The classical pathway of complement activation is:

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51)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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52)

The adverse effects of vaccines are linked to:

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53)

What vaccine should not be frozen:

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54)

The Adverse events following immunization (AEFI) are divided into:

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55)

The complement system involved in phagocytic function are:

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56)

The immune cells that is linked between innate and adaptive immunity are:

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57)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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58)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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59)

All are mechanism of action of complement but except:

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60)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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61)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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62)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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63)

The immune cells that is linked between innate and adaptive immunity are:

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64)

Which antibody is the first to be released into the blood following an infection?

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65)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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66)

Mode of IPV vaccine administration is:

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67)

The following statements are the use of passive immunization included but except one?

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68)

All are 3 main effects of complement but except:

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69)

Immunogen is:

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70)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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71)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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72)

All are therapeutic applications of polyclonal antibodies but except one?

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73)

Which of the following antibody types forms a pentamer?

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74)

What is a live attenuated vaccine?

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75)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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76)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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77)

The herd immunity is:

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78)

The immunoglobulins participated in complement system formation are:

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79)

Which of the following statement is true

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80)

What is the mode of administration for PCV-13 vaccine?

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81)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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82)

Small chemical groups on the antigen molecule that can react with antibody

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83)

Vaccination is an example of?

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84)

In an immune response the type of cell which gets activated earliest is:

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85)

Natural humoral immune response against a pathogen leads to the production of:

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86)

The main advantage of passive immunization over active immunization is that:

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87)

In the application Antigen- Antibody reaction, which one is correct?

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88)

Injection of immunoglobulin is:

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89)

The following statements are criteria for a good vaccine but which is incorrect statement?

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90)

The characteristic of antigen-antibody interactions occur in second stage:

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91)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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92)

The purpose of clinical trial of a vaccine is:

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93)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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94)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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95)

The effectiveness is:

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96)

Successful immunization can be impaired by:

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97)

All the given vaccines are attenuated or inactivated whole pathogen except:

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98)

What is the immune cell in adaptive immunity?

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99)

The type of T-cells that destroy host cells bearing foreign antigen:

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100)

An antigen is:

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101)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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102)

The role of the macrophage during an antibody response is to:

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103)

In the application Antigen- Antibody reaction, which one is correct?

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104)

The antigen-antibody interactions occur in:

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105)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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106)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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107)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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108)

Which of the following is the site of T cell maturation?

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109)

The class I MHC molecule appeared to bind with receptor of:

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110)

Adjuvant used in HPV vaccine is:

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111)

Which of the following statements are true regarding polio vaccines:

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112)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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113)

The efficacy is:

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114)

In the application Antigen- Antibody reaction, which one is correct?

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115)

All are the measure for post rabies exposure prophylaxis, but except one?

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116)

The general principle of vaccination was established by:

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117)

Graft and tumor rejection are mediated primarily by:

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118)

The technology used for the production of monoclonal antibodies is:

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119)

The complement system involved in the inflammation are:

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120)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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121)

The complement system involved in chemotaxis are:

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122)

All are immune cells in innate immune system but except:

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123)

The antibody-binding site is formed primarily by:

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124)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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125)

All are functions of immunoglobulins but except:

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126)

The cytotoxic T-cells is involved in:

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127)

Antigen presenting cells for vaccine are:

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128)

In order to elicit an immune response, a carbohydrate must be which of the following?

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129)

The immunoglobulins transport across placenta mostly:

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The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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