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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Small chemical groups on the antigen molecule that can react with antibody

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2)

All are functions of immunoglobulins but except:

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3)

The immunoglobulins participated in complement system formation are:

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4)

What is the mode of administration for BCG vaccine?

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5)

The efficacy is:

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6)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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7)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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8)

Infectious material from what illness was used to develop the first vaccine?

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9)

What is the mode of administration for PCV-13 vaccine?

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10)

Injection of immunoglobulin is:

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11)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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12)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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13)

Which of the following statement is true

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14)

Which of the following is not the function of antibody?

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15)

The adverse effects of vaccines are linked to:

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16)

All are 3 main effects of complement but except:

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17)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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18)

The classical pathway of complement activation is:

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19)

The Follicular Dendritic Cells (FDCs) is located in:

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20)

The bonds involved in antigen-antibody interactions are

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21)

The complement system involved in the inflammation are:

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22)

The purpose of clinical trial of a vaccine is:

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23)

The main advantage of passive immunization over active immunization is that:

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24)

All are examples of names of monoclonal antibodies but except one?

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25)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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26)

Injection of anti-venom to a patient for snake bite is example of?

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27)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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28)

What is the immune cell in adaptive immunity?

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29)

All are mechanism of action of complement but except:

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30)

Tetanus toxoid is usually given to humans:

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31)

All are important characteristics of innate immunity but except:

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32)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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33)

Newborns get their antibodies from mother’s milk. This is an example of?

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34)

Antigen presenting cells for vaccine are:

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35)

All are Antigen-Presenting Cells (APCs) but except:

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36)

Several of the complement components are:

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37)

Successful immunization can be impaired by:

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38)

Vaccination is an example of?

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39)

The immune cells that is linked between innate and adaptive immunity are:

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40)

Adjuvant used in HPV vaccine is:

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41)

Which of the following is the site of T cell maturation?

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42)

In the application Antigen- Antibody reaction, which one is correct?

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43)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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44)

The class II MHC molecule appeared to bind with receptor of:

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45)

Which antibody is the first to be released into the blood following an infection?

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46)

The complement system involved in phagocytic function are:

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47)

The technology used for the production of monoclonal antibodies is:

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48)

In order to elicit an immune response, a carbohydrate must be which of the following?

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49)

The first recombinant antigen vaccine approved for human use is:

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50)

The following statements are the use of passive immunization included but except one?

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51)

An immunoglobulin is a:

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52)

All are the measure for post rabies exposure prophylaxis, but except one?

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53)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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54)

The antigen-antibody interactions occur in:

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55)

The first line of defense against invading pathogens:

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56)

The characteristic of antigen-antibody interactions occur in second stage:

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57)

An epitope is:

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58)

The effectiveness is:

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59)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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60)

What vaccine should be avoided for the pregnant woman?

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61)

The impact is:

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62)

Which of the following statement is true regarding vaccination:

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63)

The naive T cells are:

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64)

The complement system consists of about:

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65)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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66)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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67)

All the following comes under non-specific defence mechanism except

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68)

The characteristic of antigen-antibody interactions occur in primary stage:

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69)

In the application Antigen- Antibody reaction, which one is correct?

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70)

Which of the following is a polysaccharide vaccine:

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71)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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72)

In the application Antigen- Antibody reaction, which one is correct?

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73)

The class I MHC molecule appeared to bind with receptor of:

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74)

The antibody-binding site is formed primarily by:

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75)

All the given vaccines are attenuated or inactivated whole pathogen except:

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76)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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77)

The type of T-cells that destroy host cells bearing foreign antigen:

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78)

What vaccine can be used for pregnant women?

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79)

Which of the following is not an ideal property of a vaccine?

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80)

The immune cells that is linked between innate and adaptive immunity are:

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81)

Natural humoral immune response against a pathogen leads to the production of:

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82)

An epitope:

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83)

The complement system involved in chemotaxis are:

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84)

Which of the following statements are true regarding polio vaccines:

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85)

What is a live attenuated vaccine?

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86)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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87)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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88)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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89)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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90)

The circulation of a two month old breast-fed baby will contain maternal:

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91)

The immunoglobulins transport across epithelium:

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92)

Which of the following antibody types forms a pentamer?

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93)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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94)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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95)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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96)

The general principle of vaccination was established by:

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97)

The classical pathway of complement activation is:

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98)

The complement system are synthesized by:

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99)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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100)

Graft and tumor rejection are mediated primarily by:

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101)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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102)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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103)

All are therapeutic applications of polyclonal antibodies but except one?

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104)

The immunoglobulins transport across placenta mostly:

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105)

The following statements are criteria for a good vaccine but which is incorrect statement?

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106)

Adjuvant used in HBV vaccine is:

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107)

Serum which contains antibodies is called:

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108)

In an immune response the type of cell which gets activated earliest is:

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109)

Immunogen is:

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110)

What vaccine should not be frozen:

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111)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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112)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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113)

Mode of IPV vaccine administration is:

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114)

Which of the following antibodies have a positive effect on babies through breast feeding?

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115)

The role of the macrophage during an antibody response is to:

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116)

The process of weakening a pathogen is called:

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117)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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118)

All are immune cells in innate immune system but except:

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119)

The Adverse events following immunization (AEFI) are divided into:

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120)

What is the mode of administration for anti-measles vaccine?

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121)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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122)

All are factors influencing in immunogenicity but except:

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123)

In the application Antigen- Antibody reaction, which one is not correct?

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124)

An antigen is:

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125)

The cytotoxic T-cells is involved in:

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126)

Primary lymphoid organs include

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127)

The herd immunity is:

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128)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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129)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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130)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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