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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

The class I MHC molecule appeared to bind with receptor of:

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2)

The bonds involved in antigen-antibody interactions are

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3)

All the given vaccines are attenuated or inactivated whole pathogen except:

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4)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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5)

The impact is:

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6)

Graft and tumor rejection are mediated primarily by:

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7)

The class II MHC molecule appeared to bind with receptor of:

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8)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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9)

In the application Antigen- Antibody reaction, which one is correct?

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10)

The main advantage of passive immunization over active immunization is that:

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11)

The antibody-binding site is formed primarily by:

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12)

All are mechanism of action of complement but except:

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13)

An immunoglobulin is a:

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14)

The Adverse events following immunization (AEFI) are divided into:

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15)

Which of the following is not the function of antibody?

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16)

Which of the following statements are true regarding polio vaccines:

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17)

What vaccine should be avoided for the pregnant woman?

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18)

In the application Antigen- Antibody reaction, which one is not correct?

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19)

What vaccine can be used for pregnant women?

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20)

What is the mode of administration for anti-measles vaccine?

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21)

The immunoglobulins transport across placenta mostly:

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22)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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23)

Which antibody is the first to be released into the blood following an infection?

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24)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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25)

The complement system are synthesized by:

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26)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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27)

The Follicular Dendritic Cells (FDCs) is located in:

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28)

Successful immunization can be impaired by:

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29)

What is a live attenuated vaccine?

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30)

Injection of immunoglobulin is:

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31)

What is the mode of administration for BCG vaccine?

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32)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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33)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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34)

All are functions of immunoglobulins but except:

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35)

The naive T cells are:

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36)

The efficacy is:

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37)

The herd immunity is:

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38)

Adjuvant used in HPV vaccine is:

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39)

Small chemical groups on the antigen molecule that can react with antibody

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40)

The antigen-antibody interactions occur in:

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41)

Which of the following statement is true regarding vaccination:

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42)

Adjuvant used in HBV vaccine is:

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43)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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44)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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45)

Vaccination is an example of?

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46)

All are immune cells in innate immune system but except:

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47)

Several of the complement components are:

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48)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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49)

The complement system consists of about:

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50)

In order to elicit an immune response, a carbohydrate must be which of the following?

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51)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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52)

The effectiveness is:

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53)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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54)

All are factors influencing in immunogenicity but except:

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55)

Serum which contains antibodies is called:

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56)

The complement system involved in phagocytic function are:

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57)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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58)

The purpose of clinical trial of a vaccine is:

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59)

The immune cells that is linked between innate and adaptive immunity are:

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60)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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61)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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62)

All are 3 main effects of complement but except:

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63)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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64)

The classical pathway of complement activation is:

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65)

All are important characteristics of innate immunity but except:

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66)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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67)

An antigen is:

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68)

What is the immune cell in adaptive immunity?

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69)

Mode of IPV vaccine administration is:

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70)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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71)

Which of the following is not an ideal property of a vaccine?

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72)

Primary lymphoid organs include

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73)

All are the measure for post rabies exposure prophylaxis, but except one?

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74)

Newborns get their antibodies from mother’s milk. This is an example of?

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75)

In the application Antigen- Antibody reaction, which one is correct?

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76)

All are examples of names of monoclonal antibodies but except one?

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77)

In the application Antigen- Antibody reaction, which one is correct?

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78)

Tetanus toxoid is usually given to humans:

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79)

In an immune response the type of cell which gets activated earliest is:

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80)

Antigen presenting cells for vaccine are:

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81)

What vaccine should not be frozen:

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82)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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83)

The characteristic of antigen-antibody interactions occur in primary stage:

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84)

The classical pathway of complement activation is:

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85)

The immunoglobulins transport across epithelium:

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86)

The technology used for the production of monoclonal antibodies is:

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87)

All are Antigen-Presenting Cells (APCs) but except:

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88)

All the following comes under non-specific defence mechanism except

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89)

Which of the following is a polysaccharide vaccine:

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90)

All are therapeutic applications of polyclonal antibodies but except one?

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91)

The following statements are the use of passive immunization included but except one?

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92)

The immune cells that is linked between innate and adaptive immunity are:

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93)

The general principle of vaccination was established by:

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94)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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95)

The process of weakening a pathogen is called:

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96)

The first recombinant antigen vaccine approved for human use is:

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97)

The characteristic of antigen-antibody interactions occur in second stage:

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98)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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99)

The complement system involved in chemotaxis are:

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100)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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101)

The type of T-cells that destroy host cells bearing foreign antigen:

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102)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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103)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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104)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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105)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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106)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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107)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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108)

Infectious material from what illness was used to develop the first vaccine?

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109)

An epitope:

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110)

Which of the following antibody types forms a pentamer?

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111)

Which of the following antibodies have a positive effect on babies through breast feeding?

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112)

The following statements are criteria for a good vaccine but which is incorrect statement?

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113)

The circulation of a two month old breast-fed baby will contain maternal:

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114)

What is the mode of administration for PCV-13 vaccine?

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115)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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116)

Immunogen is:

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117)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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118)

The role of the macrophage during an antibody response is to:

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119)

Which of the following is the site of T cell maturation?

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120)

Injection of anti-venom to a patient for snake bite is example of?

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121)

The adverse effects of vaccines are linked to:

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122)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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123)

Which of the following statement is true

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124)

The complement system involved in the inflammation are:

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125)

The immunoglobulins participated in complement system formation are:

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126)

The first line of defense against invading pathogens:

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127)

Natural humoral immune response against a pathogen leads to the production of:

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128)

An epitope is:

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129)

The cytotoxic T-cells is involved in:

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130)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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