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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

All the following comes under non-specific defence mechanism except

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2)

The immune cells that is linked between innate and adaptive immunity are:

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3)

The first recombinant antigen vaccine approved for human use is:

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4)

The complement system involved in the inflammation are:

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5)

What vaccine should be avoided for the pregnant woman?

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6)

The antigen-antibody interactions occur in:

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7)

Which of the following is a polysaccharide vaccine:

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8)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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9)

All are mechanism of action of complement but except:

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10)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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11)

Which of the following statement is true

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12)

All are therapeutic applications of polyclonal antibodies but except one?

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13)

Which of the following antibody types forms a pentamer?

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14)

All are examples of names of monoclonal antibodies but except one?

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15)

All are immune cells in innate immune system but except:

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16)

What is the mode of administration for PCV-13 vaccine?

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17)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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18)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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19)

The main advantage of passive immunization over active immunization is that:

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20)

The Follicular Dendritic Cells (FDCs) is located in:

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21)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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22)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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23)

In the application Antigen- Antibody reaction, which one is not correct?

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24)

Mode of IPV vaccine administration is:

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25)

In an immune response the type of cell which gets activated earliest is:

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26)

What is the immune cell in adaptive immunity?

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27)

What is a live attenuated vaccine?

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28)

What vaccine can be used for pregnant women?

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29)

All are important characteristics of innate immunity but except:

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30)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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31)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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32)

Injection of immunoglobulin is:

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33)

Graft and tumor rejection are mediated primarily by:

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34)

The impact is:

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35)

What vaccine should not be frozen:

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36)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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37)

All the given vaccines are attenuated or inactivated whole pathogen except:

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38)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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39)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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40)

The type of T-cells that destroy host cells bearing foreign antigen:

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41)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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42)

Infectious material from what illness was used to develop the first vaccine?

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43)

All are functions of immunoglobulins but except:

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44)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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45)

Primary lymphoid organs include

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46)

The antibody-binding site is formed primarily by:

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47)

The classical pathway of complement activation is:

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48)

The complement system consists of about:

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49)

Which of the following antibodies have a positive effect on babies through breast feeding?

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50)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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51)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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52)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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53)

Immunogen is:

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54)

The following statements are criteria for a good vaccine but which is incorrect statement?

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55)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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56)

Small chemical groups on the antigen molecule that can react with antibody

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57)

In the application Antigen- Antibody reaction, which one is correct?

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58)

Which antibody is the first to be released into the blood following an infection?

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59)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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60)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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61)

The cytotoxic T-cells is involved in:

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62)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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63)

An epitope is:

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64)

The classical pathway of complement activation is:

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65)

Antigen presenting cells for vaccine are:

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66)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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67)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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68)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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69)

The effectiveness is:

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70)

The process of weakening a pathogen is called:

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71)

The first line of defense against invading pathogens:

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72)

What is the mode of administration for BCG vaccine?

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73)

In order to elicit an immune response, a carbohydrate must be which of the following?

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74)

What is the mode of administration for anti-measles vaccine?

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75)

Vaccination is an example of?

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76)

Adjuvant used in HBV vaccine is:

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77)

An epitope:

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78)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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79)

The technology used for the production of monoclonal antibodies is:

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80)

The adverse effects of vaccines are linked to:

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81)

The immunoglobulins participated in complement system formation are:

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82)

An immunoglobulin is a:

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83)

The purpose of clinical trial of a vaccine is:

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84)

The general principle of vaccination was established by:

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85)

An antigen is:

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86)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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87)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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88)

All are the measure for post rabies exposure prophylaxis, but except one?

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89)

The characteristic of antigen-antibody interactions occur in second stage:

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90)

The role of the macrophage during an antibody response is to:

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91)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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92)

Serum which contains antibodies is called:

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93)

Several of the complement components are:

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94)

The complement system are synthesized by:

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95)

Successful immunization can be impaired by:

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96)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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97)

In the application Antigen- Antibody reaction, which one is correct?

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98)

The complement system involved in phagocytic function are:

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99)

All are 3 main effects of complement but except:

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100)

Which of the following statement is true regarding vaccination:

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101)

The immunoglobulins transport across epithelium:

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102)

Injection of anti-venom to a patient for snake bite is example of?

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103)

The Adverse events following immunization (AEFI) are divided into:

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104)

The herd immunity is:

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105)

Adjuvant used in HPV vaccine is:

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106)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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107)

The characteristic of antigen-antibody interactions occur in primary stage:

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108)

The immunoglobulins transport across placenta mostly:

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109)

Which of the following statements are true regarding polio vaccines:

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110)

The complement system involved in chemotaxis are:

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111)

Which of the following is not the function of antibody?

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112)

Natural humoral immune response against a pathogen leads to the production of:

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113)

The circulation of a two month old breast-fed baby will contain maternal:

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114)

The bonds involved in antigen-antibody interactions are

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115)

Which of the following is the site of T cell maturation?

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116)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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117)

All are Antigen-Presenting Cells (APCs) but except:

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118)

All are factors influencing in immunogenicity but except:

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119)

The naive T cells are:

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120)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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121)

The following statements are the use of passive immunization included but except one?

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122)

The class II MHC molecule appeared to bind with receptor of:

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123)

The class I MHC molecule appeared to bind with receptor of:

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124)

Newborns get their antibodies from mother’s milk. This is an example of?

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125)

Tetanus toxoid is usually given to humans:

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126)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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127)

The efficacy is:

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128)

Which of the following is not an ideal property of a vaccine?

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129)

In the application Antigen- Antibody reaction, which one is correct?

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130)

The immune cells that is linked between innate and adaptive immunity are:

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