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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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2)

In an immune response the type of cell which gets activated earliest is:

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3)

Serum which contains antibodies is called:

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4)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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5)

The naive T cells are:

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6)

Tetanus toxoid is usually given to humans:

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7)

All are immune cells in innate immune system but except:

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8)

The classical pathway of complement activation is:

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9)

All the given vaccines are attenuated or inactivated whole pathogen except:

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10)

The herd immunity is:

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11)

Natural humoral immune response against a pathogen leads to the production of:

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12)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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13)

What vaccine should not be frozen:

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14)

All are therapeutic applications of polyclonal antibodies but except one?

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15)

An antigen is:

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16)

Adjuvant used in HBV vaccine is:

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17)

In order to elicit an immune response, a carbohydrate must be which of the following?

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18)

The complement system involved in chemotaxis are:

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19)

Which of the following antibody types forms a pentamer?

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20)

In the application Antigen- Antibody reaction, which one is correct?

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21)

All the following comes under non-specific defence mechanism except

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22)

What is the mode of administration for anti-measles vaccine?

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23)

Which of the following is a polysaccharide vaccine:

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24)

The antibody-binding site is formed primarily by:

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25)

Mode of IPV vaccine administration is:

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26)

Which of the following is not an ideal property of a vaccine?

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27)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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28)

Infectious material from what illness was used to develop the first vaccine?

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29)

The Adverse events following immunization (AEFI) are divided into:

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30)

Successful immunization can be impaired by:

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31)

An epitope is:

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32)

Which of the following is not the function of antibody?

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33)

The complement system are synthesized by:

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34)

Which of the following statements are true regarding polio vaccines:

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35)

All are the measure for post rabies exposure prophylaxis, but except one?

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36)

The Follicular Dendritic Cells (FDCs) is located in:

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37)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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38)

In the application Antigen- Antibody reaction, which one is not correct?

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39)

The class II MHC molecule appeared to bind with receptor of:

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40)

What is the mode of administration for PCV-13 vaccine?

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41)

The purpose of clinical trial of a vaccine is:

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42)

The circulation of a two month old breast-fed baby will contain maternal:

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43)

The main advantage of passive immunization over active immunization is that:

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44)

The first line of defense against invading pathogens:

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45)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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46)

Which of the following antibodies have a positive effect on babies through breast feeding?

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47)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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48)

The characteristic of antigen-antibody interactions occur in second stage:

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49)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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50)

Injection of anti-venom to a patient for snake bite is example of?

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51)

The general principle of vaccination was established by:

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52)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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53)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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54)

What vaccine should be avoided for the pregnant woman?

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55)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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56)

Small chemical groups on the antigen molecule that can react with antibody

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57)

An immunoglobulin is a:

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58)

The efficacy is:

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59)

The cytotoxic T-cells is involved in:

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60)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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61)

Newborns get their antibodies from mother’s milk. This is an example of?

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62)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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63)

The technology used for the production of monoclonal antibodies is:

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64)

The complement system involved in phagocytic function are:

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65)

Which of the following is the site of T cell maturation?

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66)

Immunogen is:

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67)

What is the immune cell in adaptive immunity?

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68)

An epitope:

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69)

The immunoglobulins participated in complement system formation are:

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70)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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71)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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72)

Several of the complement components are:

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73)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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74)

The immune cells that is linked between innate and adaptive immunity are:

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75)

All are mechanism of action of complement but except:

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76)

The first recombinant antigen vaccine approved for human use is:

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77)

Which antibody is the first to be released into the blood following an infection?

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78)

What is a live attenuated vaccine?

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79)

Vaccination is an example of?

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80)

Injection of immunoglobulin is:

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81)

The immune cells that is linked between innate and adaptive immunity are:

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82)

All are examples of names of monoclonal antibodies but except one?

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83)

The following statements are criteria for a good vaccine but which is incorrect statement?

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84)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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85)

Graft and tumor rejection are mediated primarily by:

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86)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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87)

The complement system consists of about:

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88)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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89)

The antigen-antibody interactions occur in:

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90)

The immunoglobulins transport across epithelium:

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91)

Adjuvant used in HPV vaccine is:

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92)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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93)

The type of T-cells that destroy host cells bearing foreign antigen:

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94)

All are important characteristics of innate immunity but except:

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95)

All are factors influencing in immunogenicity but except:

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96)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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97)

In the application Antigen- Antibody reaction, which one is correct?

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98)

The immunoglobulins transport across placenta mostly:

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99)

Primary lymphoid organs include

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100)

In the application Antigen- Antibody reaction, which one is correct?

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101)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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102)

The complement system involved in the inflammation are:

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103)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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104)

The bonds involved in antigen-antibody interactions are

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105)

The process of weakening a pathogen is called:

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106)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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107)

Which of the following statement is true regarding vaccination:

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108)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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109)

The effectiveness is:

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110)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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111)

Which of the following statement is true

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112)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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113)

Antigen presenting cells for vaccine are:

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114)

What is the mode of administration for BCG vaccine?

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115)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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116)

The impact is:

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117)

All are 3 main effects of complement but except:

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118)

The adverse effects of vaccines are linked to:

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119)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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120)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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121)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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122)

The characteristic of antigen-antibody interactions occur in primary stage:

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123)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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124)

All are Antigen-Presenting Cells (APCs) but except:

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125)

The role of the macrophage during an antibody response is to:

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126)

The classical pathway of complement activation is:

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127)

All are functions of immunoglobulins but except:

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128)

The class I MHC molecule appeared to bind with receptor of:

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129)

What vaccine can be used for pregnant women?

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130)

The following statements are the use of passive immunization included but except one?

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