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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Which of the following antibodies have a positive effect on babies through breast feeding?

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2)

All are functions of immunoglobulins but except:

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3)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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4)

The complement system consists of about:

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5)

The general principle of vaccination was established by:

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6)

The first recombinant antigen vaccine approved for human use is:

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7)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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8)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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9)

The characteristic of antigen-antibody interactions occur in second stage:

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10)

Adjuvant used in HBV vaccine is:

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11)

The adverse effects of vaccines are linked to:

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12)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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13)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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14)

The Follicular Dendritic Cells (FDCs) is located in:

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15)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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16)

What is a live attenuated vaccine?

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17)

What is the mode of administration for PCV-13 vaccine?

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18)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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19)

The efficacy is:

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20)

The bonds involved in antigen-antibody interactions are

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21)

Which of the following is not the function of antibody?

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22)

The impact is:

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23)

Injection of anti-venom to a patient for snake bite is example of?

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24)

The class II MHC molecule appeared to bind with receptor of:

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25)

Adjuvant used in HPV vaccine is:

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26)

An epitope:

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27)

What is the mode of administration for BCG vaccine?

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28)

In an immune response the type of cell which gets activated earliest is:

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29)

Mode of IPV vaccine administration is:

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30)

Which of the following is not an ideal property of a vaccine?

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31)

Which of the following is a polysaccharide vaccine:

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32)

The main advantage of passive immunization over active immunization is that:

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33)

Successful immunization can be impaired by:

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34)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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35)

The herd immunity is:

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36)

Newborns get their antibodies from mother’s milk. This is an example of?

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37)

All are the measure for post rabies exposure prophylaxis, but except one?

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38)

The complement system involved in the inflammation are:

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39)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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40)

Which antibody is the first to be released into the blood following an infection?

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41)

The characteristic of antigen-antibody interactions occur in primary stage:

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42)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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43)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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44)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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45)

Which of the following statement is true regarding vaccination:

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46)

All are therapeutic applications of polyclonal antibodies but except one?

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47)

Tetanus toxoid is usually given to humans:

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48)

The immunoglobulins transport across epithelium:

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49)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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50)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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51)

All are important characteristics of innate immunity but except:

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52)

Several of the complement components are:

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53)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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54)

Primary lymphoid organs include

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55)

What vaccine should be avoided for the pregnant woman?

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56)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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57)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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58)

The immune cells that is linked between innate and adaptive immunity are:

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59)

Which of the following is the site of T cell maturation?

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60)

The effectiveness is:

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61)

The following statements are criteria for a good vaccine but which is incorrect statement?

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62)

In the application Antigen- Antibody reaction, which one is correct?

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63)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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64)

The type of T-cells that destroy host cells bearing foreign antigen:

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65)

All are Antigen-Presenting Cells (APCs) but except:

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66)

All are examples of names of monoclonal antibodies but except one?

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67)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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68)

Injection of immunoglobulin is:

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69)

The technology used for the production of monoclonal antibodies is:

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70)

Which of the following statements are true regarding polio vaccines:

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71)

The classical pathway of complement activation is:

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72)

What vaccine can be used for pregnant women?

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73)

An immunoglobulin is a:

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74)

What is the immune cell in adaptive immunity?

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75)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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76)

The Adverse events following immunization (AEFI) are divided into:

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77)

All are factors influencing in immunogenicity but except:

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78)

The naive T cells are:

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79)

The immunoglobulins transport across placenta mostly:

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80)

All are mechanism of action of complement but except:

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81)

The following statements are the use of passive immunization included but except one?

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82)

The antigen-antibody interactions occur in:

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83)

The role of the macrophage during an antibody response is to:

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84)

What vaccine should not be frozen:

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85)

An antigen is:

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86)

In order to elicit an immune response, a carbohydrate must be which of the following?

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87)

The antibody-binding site is formed primarily by:

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88)

All are 3 main effects of complement but except:

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89)

The classical pathway of complement activation is:

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90)

Immunogen is:

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91)

The process of weakening a pathogen is called:

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92)

The complement system involved in chemotaxis are:

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93)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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94)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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95)

What is the mode of administration for anti-measles vaccine?

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96)

Which of the following antibody types forms a pentamer?

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97)

Graft and tumor rejection are mediated primarily by:

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98)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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99)

All are immune cells in innate immune system but except:

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100)

The class I MHC molecule appeared to bind with receptor of:

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101)

The complement system are synthesized by:

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102)

Antigen presenting cells for vaccine are:

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103)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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104)

The complement system involved in phagocytic function are:

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105)

In the application Antigen- Antibody reaction, which one is correct?

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106)

Vaccination is an example of?

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107)

In the application Antigen- Antibody reaction, which one is correct?

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108)

Which of the following statement is true

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109)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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110)

The cytotoxic T-cells is involved in:

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111)

The first line of defense against invading pathogens:

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112)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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113)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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114)

Serum which contains antibodies is called:

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115)

The purpose of clinical trial of a vaccine is:

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116)

All the given vaccines are attenuated or inactivated whole pathogen except:

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117)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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118)

The immunoglobulins participated in complement system formation are:

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119)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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120)

Small chemical groups on the antigen molecule that can react with antibody

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121)

In the application Antigen- Antibody reaction, which one is not correct?

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122)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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123)

Infectious material from what illness was used to develop the first vaccine?

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124)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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125)

An epitope is:

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126)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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127)

The circulation of a two month old breast-fed baby will contain maternal:

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128)

All the following comes under non-specific defence mechanism except

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129)

The immune cells that is linked between innate and adaptive immunity are:

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130)

Natural humoral immune response against a pathogen leads to the production of:

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