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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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2)

Infectious material from what illness was used to develop the first vaccine?

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3)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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4)

All are important characteristics of innate immunity but except:

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5)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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6)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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7)

The antibody-binding site is formed primarily by:

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8)

The complement system involved in the inflammation are:

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9)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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10)

The first line of defense against invading pathogens:

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11)

The complement system involved in chemotaxis are:

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12)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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13)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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14)

Which of the following statements are true regarding polio vaccines:

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15)

Immunogen is:

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16)

The role of the macrophage during an antibody response is to:

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17)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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18)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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19)

The following statements are criteria for a good vaccine but which is incorrect statement?

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20)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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21)

All are Antigen-Presenting Cells (APCs) but except:

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22)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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23)

In an immune response the type of cell which gets activated earliest is:

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24)

Vaccination is an example of?

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25)

An epitope:

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26)

The complement system involved in phagocytic function are:

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27)

All are immune cells in innate immune system but except:

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28)

In the application Antigen- Antibody reaction, which one is correct?

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29)

The effectiveness is:

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30)

An immunoglobulin is a:

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31)

Graft and tumor rejection are mediated primarily by:

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32)

Antigen presenting cells for vaccine are:

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33)

In order to elicit an immune response, a carbohydrate must be which of the following?

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34)

The characteristic of antigen-antibody interactions occur in primary stage:

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35)

The immunoglobulins transport across placenta mostly:

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36)

The Follicular Dendritic Cells (FDCs) is located in:

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37)

Natural humoral immune response against a pathogen leads to the production of:

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38)

In the application Antigen- Antibody reaction, which one is not correct?

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39)

The cytotoxic T-cells is involved in:

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40)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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41)

Small chemical groups on the antigen molecule that can react with antibody

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42)

What is the mode of administration for PCV-13 vaccine?

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43)

The immune cells that is linked between innate and adaptive immunity are:

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44)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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45)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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46)

The Adverse events following immunization (AEFI) are divided into:

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47)

Injection of immunoglobulin is:

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48)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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49)

What vaccine should not be frozen:

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50)

Which of the following is not the function of antibody?

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51)

What is the immune cell in adaptive immunity?

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52)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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53)

Which of the following antibody types forms a pentamer?

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54)

An antigen is:

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55)

Primary lymphoid organs include

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56)

Serum which contains antibodies is called:

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57)

Several of the complement components are:

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58)

All the following comes under non-specific defence mechanism except

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59)

Mode of IPV vaccine administration is:

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60)

The class I MHC molecule appeared to bind with receptor of:

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61)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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62)

The process of weakening a pathogen is called:

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63)

The bonds involved in antigen-antibody interactions are

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64)

All the given vaccines are attenuated or inactivated whole pathogen except:

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65)

Which of the following is a polysaccharide vaccine:

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66)

The classical pathway of complement activation is:

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67)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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68)

The purpose of clinical trial of a vaccine is:

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69)

The immunoglobulins participated in complement system formation are:

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70)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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71)

All are therapeutic applications of polyclonal antibodies but except one?

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72)

Adjuvant used in HBV vaccine is:

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73)

Which of the following is not an ideal property of a vaccine?

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74)

All are examples of names of monoclonal antibodies but except one?

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75)

All are the measure for post rabies exposure prophylaxis, but except one?

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76)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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77)

An epitope is:

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78)

What vaccine can be used for pregnant women?

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79)

The general principle of vaccination was established by:

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80)

What is a live attenuated vaccine?

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81)

In the application Antigen- Antibody reaction, which one is correct?

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82)

Which of the following antibodies have a positive effect on babies through breast feeding?

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83)

The technology used for the production of monoclonal antibodies is:

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84)

The complement system consists of about:

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85)

The first recombinant antigen vaccine approved for human use is:

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86)

Which of the following statement is true

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87)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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88)

The adverse effects of vaccines are linked to:

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89)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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90)

In the application Antigen- Antibody reaction, which one is correct?

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91)

Which of the following is the site of T cell maturation?

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92)

The complement system are synthesized by:

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93)

The type of T-cells that destroy host cells bearing foreign antigen:

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94)

All are factors influencing in immunogenicity but except:

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95)

The herd immunity is:

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96)

The characteristic of antigen-antibody interactions occur in second stage:

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97)

Injection of anti-venom to a patient for snake bite is example of?

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98)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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99)

The impact is:

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100)

Newborns get their antibodies from mother’s milk. This is an example of?

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101)

Adjuvant used in HPV vaccine is:

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102)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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103)

The antigen-antibody interactions occur in:

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104)

The classical pathway of complement activation is:

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105)

The efficacy is:

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106)

The main advantage of passive immunization over active immunization is that:

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107)

All are functions of immunoglobulins but except:

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108)

The following statements are the use of passive immunization included but except one?

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109)

Which antibody is the first to be released into the blood following an infection?

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110)

Successful immunization can be impaired by:

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111)

What is the mode of administration for anti-measles vaccine?

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112)

The immunoglobulins transport across epithelium:

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113)

The immune cells that is linked between innate and adaptive immunity are:

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114)

The circulation of a two month old breast-fed baby will contain maternal:

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115)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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116)

Tetanus toxoid is usually given to humans:

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117)

What vaccine should be avoided for the pregnant woman?

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118)

The naive T cells are:

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119)

What is the mode of administration for BCG vaccine?

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120)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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121)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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122)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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123)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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124)

Which of the following statement is true regarding vaccination:

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125)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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126)

All are mechanism of action of complement but except:

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127)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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128)

All are 3 main effects of complement but except:

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129)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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130)

The class II MHC molecule appeared to bind with receptor of:

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