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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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2)

In an immune response the type of cell which gets activated earliest is:

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3)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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4)

Serum which contains antibodies is called:

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5)

Successful immunization can be impaired by:

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6)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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7)

Adjuvant used in HBV vaccine is:

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8)

The immunoglobulins transport across epithelium:

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9)

The role of the macrophage during an antibody response is to:

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10)

The immune cells that is linked between innate and adaptive immunity are:

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11)

Immunogen is:

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12)

The cytotoxic T-cells is involved in:

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13)

All are mechanism of action of complement but except:

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14)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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15)

The antibody-binding site is formed primarily by:

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16)

The technology used for the production of monoclonal antibodies is:

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17)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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18)

Which of the following is not the function of antibody?

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19)

Small chemical groups on the antigen molecule that can react with antibody

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20)

All are examples of names of monoclonal antibodies but except one?

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21)

An antigen is:

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22)

The type of T-cells that destroy host cells bearing foreign antigen:

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23)

The complement system involved in the inflammation are:

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24)

Which antibody is the first to be released into the blood following an infection?

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25)

An epitope is:

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26)

The complement system involved in phagocytic function are:

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27)

The characteristic of antigen-antibody interactions occur in primary stage:

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28)

The immune cells that is linked between innate and adaptive immunity are:

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29)

The characteristic of antigen-antibody interactions occur in second stage:

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30)

Which of the following antibody types forms a pentamer?

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31)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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32)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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33)

The first recombinant antigen vaccine approved for human use is:

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34)

The herd immunity is:

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35)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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36)

The circulation of a two month old breast-fed baby will contain maternal:

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37)

The efficacy is:

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38)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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39)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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40)

The impact is:

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41)

All the given vaccines are attenuated or inactivated whole pathogen except:

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42)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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43)

Primary lymphoid organs include

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44)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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45)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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46)

The purpose of clinical trial of a vaccine is:

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47)

The following statements are the use of passive immunization included but except one?

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48)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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49)

The Follicular Dendritic Cells (FDCs) is located in:

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50)

The naive T cells are:

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51)

Several of the complement components are:

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52)

Adjuvant used in HPV vaccine is:

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53)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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54)

The bonds involved in antigen-antibody interactions are

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55)

The effectiveness is:

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56)

The complement system consists of about:

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57)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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58)

The general principle of vaccination was established by:

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59)

Natural humoral immune response against a pathogen leads to the production of:

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60)

Graft and tumor rejection are mediated primarily by:

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61)

All are functions of immunoglobulins but except:

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62)

In the application Antigen- Antibody reaction, which one is correct?

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63)

What is the immune cell in adaptive immunity?

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64)

All are immune cells in innate immune system but except:

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65)

The immunoglobulins transport across placenta mostly:

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66)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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67)

All are important characteristics of innate immunity but except:

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68)

The process of weakening a pathogen is called:

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69)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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70)

Injection of anti-venom to a patient for snake bite is example of?

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71)

All are factors influencing in immunogenicity but except:

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72)

The first line of defense against invading pathogens:

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73)

In order to elicit an immune response, a carbohydrate must be which of the following?

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74)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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75)

All the following comes under non-specific defence mechanism except

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76)

Antigen presenting cells for vaccine are:

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77)

What is the mode of administration for PCV-13 vaccine?

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78)

Newborns get their antibodies from mother’s milk. This is an example of?

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79)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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80)

All are Antigen-Presenting Cells (APCs) but except:

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81)

What vaccine should not be frozen:

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82)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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83)

Tetanus toxoid is usually given to humans:

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84)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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85)

The following statements are criteria for a good vaccine but which is incorrect statement?

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86)

Which of the following is the site of T cell maturation?

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87)

All are the measure for post rabies exposure prophylaxis, but except one?

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88)

An immunoglobulin is a:

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89)

What vaccine should be avoided for the pregnant woman?

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90)

Which of the following statement is true

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91)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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92)

What is the mode of administration for anti-measles vaccine?

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93)

What is the mode of administration for BCG vaccine?

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94)

Which of the following antibodies have a positive effect on babies through breast feeding?

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95)

What vaccine can be used for pregnant women?

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96)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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97)

In the application Antigen- Antibody reaction, which one is correct?

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98)

The class I MHC molecule appeared to bind with receptor of:

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99)

Which of the following is not an ideal property of a vaccine?

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100)

The classical pathway of complement activation is:

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101)

Vaccination is an example of?

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102)

An epitope:

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103)

Infectious material from what illness was used to develop the first vaccine?

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104)

All are therapeutic applications of polyclonal antibodies but except one?

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105)

Mode of IPV vaccine administration is:

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106)

The class II MHC molecule appeared to bind with receptor of:

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107)

The complement system are synthesized by:

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108)

The main advantage of passive immunization over active immunization is that:

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109)

The Adverse events following immunization (AEFI) are divided into:

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110)

What is a live attenuated vaccine?

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111)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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112)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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113)

Which of the following is a polysaccharide vaccine:

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114)

In the application Antigen- Antibody reaction, which one is not correct?

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115)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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116)

The adverse effects of vaccines are linked to:

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117)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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118)

The classical pathway of complement activation is:

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119)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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120)

Injection of immunoglobulin is:

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121)

In the application Antigen- Antibody reaction, which one is correct?

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122)

The immunoglobulins participated in complement system formation are:

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123)

Which of the following statement is true regarding vaccination:

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124)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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125)

The complement system involved in chemotaxis are:

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126)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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127)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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128)

All are 3 main effects of complement but except:

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129)

The antigen-antibody interactions occur in:

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130)

Which of the following statements are true regarding polio vaccines:

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