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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Injection of immunoglobulin is:

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2)

Immunogen is:

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3)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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4)

Which antibody is the first to be released into the blood following an infection?

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5)

The technology used for the production of monoclonal antibodies is:

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6)

The herd immunity is:

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7)

All are important characteristics of innate immunity but except:

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8)

The naive T cells are:

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9)

Which of the following is the site of T cell maturation?

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10)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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11)

Which of the following is not the function of antibody?

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12)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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13)

The classical pathway of complement activation is:

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14)

Infectious material from what illness was used to develop the first vaccine?

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15)

All are 3 main effects of complement but except:

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16)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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17)

Which of the following statement is true regarding vaccination:

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18)

Which of the following antibodies have a positive effect on babies through breast feeding?

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19)

Serum which contains antibodies is called:

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20)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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21)

The cytotoxic T-cells is involved in:

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22)

The complement system consists of about:

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23)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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24)

The complement system involved in the inflammation are:

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25)

What is the mode of administration for BCG vaccine?

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26)

All are Antigen-Presenting Cells (APCs) but except:

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27)

The characteristic of antigen-antibody interactions occur in second stage:

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28)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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29)

All the following comes under non-specific defence mechanism except

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30)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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31)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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32)

Which of the following statement is true

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33)

All are the measure for post rabies exposure prophylaxis, but except one?

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34)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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35)

The immunoglobulins transport across placenta mostly:

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36)

Which of the following is a polysaccharide vaccine:

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37)

In the application Antigen- Antibody reaction, which one is correct?

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38)

What vaccine should not be frozen:

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39)

What is the mode of administration for anti-measles vaccine?

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40)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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41)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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42)

The impact is:

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43)

The first line of defense against invading pathogens:

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44)

Graft and tumor rejection are mediated primarily by:

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45)

All are examples of names of monoclonal antibodies but except one?

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46)

The complement system involved in chemotaxis are:

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47)

In an immune response the type of cell which gets activated earliest is:

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48)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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49)

The immune cells that is linked between innate and adaptive immunity are:

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50)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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51)

What is a live attenuated vaccine?

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52)

The bonds involved in antigen-antibody interactions are

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53)

The process of weakening a pathogen is called:

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54)

The complement system are synthesized by:

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55)

The immunoglobulins transport across epithelium:

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56)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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57)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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58)

What vaccine should be avoided for the pregnant woman?

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59)

In order to elicit an immune response, a carbohydrate must be which of the following?

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60)

Primary lymphoid organs include

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61)

In the application Antigen- Antibody reaction, which one is not correct?

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62)

An immunoglobulin is a:

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63)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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64)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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65)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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66)

All are functions of immunoglobulins but except:

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67)

Tetanus toxoid is usually given to humans:

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68)

The circulation of a two month old breast-fed baby will contain maternal:

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69)

In the application Antigen- Antibody reaction, which one is correct?

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70)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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71)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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72)

The Adverse events following immunization (AEFI) are divided into:

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73)

The efficacy is:

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74)

Antigen presenting cells for vaccine are:

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75)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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76)

The general principle of vaccination was established by:

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77)

All the given vaccines are attenuated or inactivated whole pathogen except:

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78)

Adjuvant used in HPV vaccine is:

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79)

What is the mode of administration for PCV-13 vaccine?

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80)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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81)

The purpose of clinical trial of a vaccine is:

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82)

All are immune cells in innate immune system but except:

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83)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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84)

The role of the macrophage during an antibody response is to:

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85)

Successful immunization can be impaired by:

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86)

Which of the following is not an ideal property of a vaccine?

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87)

Mode of IPV vaccine administration is:

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88)

The antigen-antibody interactions occur in:

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89)

The immunoglobulins participated in complement system formation are:

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90)

The characteristic of antigen-antibody interactions occur in primary stage:

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91)

Several of the complement components are:

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92)

The type of T-cells that destroy host cells bearing foreign antigen:

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93)

The antibody-binding site is formed primarily by:

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94)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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95)

The main advantage of passive immunization over active immunization is that:

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96)

In the application Antigen- Antibody reaction, which one is correct?

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97)

All are factors influencing in immunogenicity but except:

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98)

The effectiveness is:

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99)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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100)

What vaccine can be used for pregnant women?

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101)

The immune cells that is linked between innate and adaptive immunity are:

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102)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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103)

The classical pathway of complement activation is:

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104)

Newborns get their antibodies from mother’s milk. This is an example of?

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105)

An epitope:

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106)

The following statements are criteria for a good vaccine but which is incorrect statement?

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107)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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108)

Adjuvant used in HBV vaccine is:

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109)

The class I MHC molecule appeared to bind with receptor of:

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110)

Natural humoral immune response against a pathogen leads to the production of:

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111)

Vaccination is an example of?

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112)

The class II MHC molecule appeared to bind with receptor of:

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113)

The Follicular Dendritic Cells (FDCs) is located in:

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114)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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115)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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116)

What is the immune cell in adaptive immunity?

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117)

Which of the following antibody types forms a pentamer?

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118)

The complement system involved in phagocytic function are:

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119)

The following statements are the use of passive immunization included but except one?

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120)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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121)

Which of the following statements are true regarding polio vaccines:

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122)

An epitope is:

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123)

All are mechanism of action of complement but except:

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124)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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125)

An antigen is:

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126)

All are therapeutic applications of polyclonal antibodies but except one?

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127)

Small chemical groups on the antigen molecule that can react with antibody

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128)

The adverse effects of vaccines are linked to:

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129)

Injection of anti-venom to a patient for snake bite is example of?

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The first recombinant antigen vaccine approved for human use is:

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