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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

The characteristic of antigen-antibody interactions occur in primary stage:

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2)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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3)

The immunoglobulins transport across epithelium:

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4)

The characteristic of antigen-antibody interactions occur in second stage:

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5)

Vaccination is an example of?

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6)

The immunoglobulins transport across placenta mostly:

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7)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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8)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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9)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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10)

The complement system involved in chemotaxis are:

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11)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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12)

In the application Antigen- Antibody reaction, which one is correct?

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13)

The antibody-binding site is formed primarily by:

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14)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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15)

An epitope is:

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16)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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17)

In the application Antigen- Antibody reaction, which one is correct?

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18)

The Follicular Dendritic Cells (FDCs) is located in:

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19)

The complement system involved in phagocytic function are:

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20)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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21)

What is the mode of administration for anti-measles vaccine?

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22)

All are factors influencing in immunogenicity but except:

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23)

In order to elicit an immune response, a carbohydrate must be which of the following?

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24)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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25)

The classical pathway of complement activation is:

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26)

In the application Antigen- Antibody reaction, which one is correct?

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27)

The class II MHC molecule appeared to bind with receptor of:

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28)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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29)

The impact is:

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30)

All are 3 main effects of complement but except:

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31)

Which of the following is not an ideal property of a vaccine?

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32)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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33)

Immunogen is:

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34)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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35)

Which of the following is not the function of antibody?

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36)

The immunoglobulins participated in complement system formation are:

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37)

What is a live attenuated vaccine?

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38)

The classical pathway of complement activation is:

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39)

The first line of defense against invading pathogens:

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40)

The efficacy is:

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41)

All are mechanism of action of complement but except:

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42)

All are the measure for post rabies exposure prophylaxis, but except one?

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43)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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44)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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45)

The circulation of a two month old breast-fed baby will contain maternal:

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46)

Successful immunization can be impaired by:

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47)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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48)

Injection of anti-venom to a patient for snake bite is example of?

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49)

Natural humoral immune response against a pathogen leads to the production of:

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50)

The complement system consists of about:

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51)

All the given vaccines are attenuated or inactivated whole pathogen except:

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52)

The general principle of vaccination was established by:

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53)

What is the mode of administration for BCG vaccine?

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54)

Tetanus toxoid is usually given to humans:

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55)

The type of T-cells that destroy host cells bearing foreign antigen:

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56)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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57)

Injection of immunoglobulin is:

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58)

Which of the following antibody types forms a pentamer?

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59)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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60)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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61)

Serum which contains antibodies is called:

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62)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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63)

All are immune cells in innate immune system but except:

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64)

The first recombinant antigen vaccine approved for human use is:

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65)

The antigen-antibody interactions occur in:

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66)

Mode of IPV vaccine administration is:

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67)

The bonds involved in antigen-antibody interactions are

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68)

The main advantage of passive immunization over active immunization is that:

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69)

All are important characteristics of innate immunity but except:

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70)

All the following comes under non-specific defence mechanism except

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71)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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72)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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73)

Which of the following antibodies have a positive effect on babies through breast feeding?

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74)

The following statements are criteria for a good vaccine but which is incorrect statement?

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75)

The complement system are synthesized by:

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76)

The cytotoxic T-cells is involved in:

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77)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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78)

Infectious material from what illness was used to develop the first vaccine?

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79)

Adjuvant used in HPV vaccine is:

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80)

Which of the following statement is true

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81)

The role of the macrophage during an antibody response is to:

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82)

Small chemical groups on the antigen molecule that can react with antibody

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83)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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84)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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85)

In the application Antigen- Antibody reaction, which one is not correct?

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86)

An immunoglobulin is a:

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87)

What vaccine should not be frozen:

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88)

Which of the following statements are true regarding polio vaccines:

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89)

Newborns get their antibodies from mother’s milk. This is an example of?

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90)

Which of the following is a polysaccharide vaccine:

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91)

In an immune response the type of cell which gets activated earliest is:

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92)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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93)

An antigen is:

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94)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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95)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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96)

The complement system involved in the inflammation are:

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97)

Which of the following is the site of T cell maturation?

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98)

All are therapeutic applications of polyclonal antibodies but except one?

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99)

The purpose of clinical trial of a vaccine is:

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100)

The adverse effects of vaccines are linked to:

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101)

The naive T cells are:

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102)

Which of the following statement is true regarding vaccination:

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103)

The process of weakening a pathogen is called:

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104)

The Adverse events following immunization (AEFI) are divided into:

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105)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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106)

The effectiveness is:

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107)

An epitope:

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108)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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109)

The immune cells that is linked between innate and adaptive immunity are:

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110)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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111)

Adjuvant used in HBV vaccine is:

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112)

The following statements are the use of passive immunization included but except one?

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113)

What is the mode of administration for PCV-13 vaccine?

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114)

All are functions of immunoglobulins but except:

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115)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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116)

What is the immune cell in adaptive immunity?

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117)

What vaccine can be used for pregnant women?

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118)

What vaccine should be avoided for the pregnant woman?

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119)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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120)

The technology used for the production of monoclonal antibodies is:

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121)

The immune cells that is linked between innate and adaptive immunity are:

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122)

The class I MHC molecule appeared to bind with receptor of:

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123)

Graft and tumor rejection are mediated primarily by:

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124)

The herd immunity is:

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125)

Several of the complement components are:

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126)

Which antibody is the first to be released into the blood following an infection?

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127)

All are examples of names of monoclonal antibodies but except one?

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128)

Primary lymphoid organs include

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All are Antigen-Presenting Cells (APCs) but except:

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Antigen presenting cells for vaccine are:

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