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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

All the given vaccines are attenuated or inactivated whole pathogen except:

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2)

Infectious material from what illness was used to develop the first vaccine?

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3)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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4)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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5)

An immunoglobulin is a:

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6)

Which of the following is a polysaccharide vaccine:

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7)

The main advantage of passive immunization over active immunization is that:

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8)

Which of the following is not an ideal property of a vaccine?

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9)

The following statements are criteria for a good vaccine but which is incorrect statement?

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10)

The cytotoxic T-cells is involved in:

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11)

All the following comes under non-specific defence mechanism except

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12)

Which of the following statement is true regarding vaccination:

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13)

The complement system are synthesized by:

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14)

An epitope is:

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15)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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16)

The process of weakening a pathogen is called:

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17)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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18)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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19)

The classical pathway of complement activation is:

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20)

Mode of IPV vaccine administration is:

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21)

The effectiveness is:

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22)

The Adverse events following immunization (AEFI) are divided into:

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23)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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24)

In the application Antigen- Antibody reaction, which one is correct?

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25)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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26)

The class II MHC molecule appeared to bind with receptor of:

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27)

In the application Antigen- Antibody reaction, which one is correct?

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28)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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29)

The immunoglobulins transport across placenta mostly:

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30)

Newborns get their antibodies from mother’s milk. This is an example of?

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31)

Tetanus toxoid is usually given to humans:

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32)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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33)

Natural humoral immune response against a pathogen leads to the production of:

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34)

Primary lymphoid organs include

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35)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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36)

What vaccine should not be frozen:

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37)

All are Antigen-Presenting Cells (APCs) but except:

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38)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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39)

What is a live attenuated vaccine?

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40)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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41)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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42)

All are the measure for post rabies exposure prophylaxis, but except one?

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43)

Successful immunization can be impaired by:

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44)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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45)

What vaccine can be used for pregnant women?

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46)

The technology used for the production of monoclonal antibodies is:

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47)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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48)

Immunogen is:

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49)

Graft and tumor rejection are mediated primarily by:

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50)

Which antibody is the first to be released into the blood following an infection?

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51)

All are important characteristics of innate immunity but except:

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52)

Vaccination is an example of?

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53)

All are 3 main effects of complement but except:

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54)

The immune cells that is linked between innate and adaptive immunity are:

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55)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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56)

Adjuvant used in HPV vaccine is:

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57)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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58)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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59)

Which of the following antibody types forms a pentamer?

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60)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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61)

All are immune cells in innate immune system but except:

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62)

The antigen-antibody interactions occur in:

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63)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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64)

Small chemical groups on the antigen molecule that can react with antibody

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65)

The purpose of clinical trial of a vaccine is:

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66)

Which of the following statement is true

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67)

Several of the complement components are:

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68)

An antigen is:

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69)

All are functions of immunoglobulins but except:

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The impact is:

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71)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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72)

The Follicular Dendritic Cells (FDCs) is located in:

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73)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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74)

The complement system involved in chemotaxis are:

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75)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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76)

What is the immune cell in adaptive immunity?

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77)

The complement system involved in the inflammation are:

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78)

Injection of anti-venom to a patient for snake bite is example of?

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79)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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80)

What is the mode of administration for PCV-13 vaccine?

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81)

The complement system consists of about:

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82)

Which of the following statements are true regarding polio vaccines:

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83)

Adjuvant used in HBV vaccine is:

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84)

The efficacy is:

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85)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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86)

The circulation of a two month old breast-fed baby will contain maternal:

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87)

The first recombinant antigen vaccine approved for human use is:

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88)

The following statements are the use of passive immunization included but except one?

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89)

In an immune response the type of cell which gets activated earliest is:

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90)

All are examples of names of monoclonal antibodies but except one?

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91)

The herd immunity is:

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92)

The adverse effects of vaccines are linked to:

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93)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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94)

The bonds involved in antigen-antibody interactions are

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95)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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96)

The type of T-cells that destroy host cells bearing foreign antigen:

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97)

All are therapeutic applications of polyclonal antibodies but except one?

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98)

The immunoglobulins participated in complement system formation are:

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99)

The immunoglobulins transport across epithelium:

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100)

Serum which contains antibodies is called:

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101)

The first line of defense against invading pathogens:

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102)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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103)

An epitope:

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104)

The classical pathway of complement activation is:

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105)

All are mechanism of action of complement but except:

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106)

The naive T cells are:

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107)

Which of the following antibodies have a positive effect on babies through breast feeding?

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108)

The characteristic of antigen-antibody interactions occur in primary stage:

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109)

In the application Antigen- Antibody reaction, which one is correct?

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110)

The class I MHC molecule appeared to bind with receptor of:

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111)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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112)

What is the mode of administration for anti-measles vaccine?

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113)

Which of the following is the site of T cell maturation?

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114)

Which of the following is not the function of antibody?

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115)

Injection of immunoglobulin is:

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116)

Antigen presenting cells for vaccine are:

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117)

The role of the macrophage during an antibody response is to:

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118)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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119)

The general principle of vaccination was established by:

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120)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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121)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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122)

In order to elicit an immune response, a carbohydrate must be which of the following?

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123)

What is the mode of administration for BCG vaccine?

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124)

In the application Antigen- Antibody reaction, which one is not correct?

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125)

The characteristic of antigen-antibody interactions occur in second stage:

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126)

All are factors influencing in immunogenicity but except:

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127)

The immune cells that is linked between innate and adaptive immunity are:

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128)

The antibody-binding site is formed primarily by:

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129)

The complement system involved in phagocytic function are:

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130)

What vaccine should be avoided for the pregnant woman?

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