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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

The Adverse events following immunization (AEFI) are divided into:

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2)

The complement system involved in the inflammation are:

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3)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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4)

What is the mode of administration for BCG vaccine?

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5)

What vaccine should not be frozen:

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6)

All are therapeutic applications of polyclonal antibodies but except one?

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7)

Immunogen is:

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8)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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9)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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10)

In an immune response the type of cell which gets activated earliest is:

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11)

Vaccination is an example of?

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12)

The antibody-binding site is formed primarily by:

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13)

What is the immune cell in adaptive immunity?

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14)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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15)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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16)

The type of T-cells that destroy host cells bearing foreign antigen:

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17)

The cytotoxic T-cells is involved in:

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18)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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19)

An antigen is:

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20)

Infectious material from what illness was used to develop the first vaccine?

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21)

What is the mode of administration for PCV-13 vaccine?

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22)

The first line of defense against invading pathogens:

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23)

The herd immunity is:

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24)

Successful immunization can be impaired by:

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25)

The impact is:

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26)

Several of the complement components are:

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27)

Which of the following antibody types forms a pentamer?

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28)

Injection of anti-venom to a patient for snake bite is example of?

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29)

The immunoglobulins transport across epithelium:

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30)

All are Antigen-Presenting Cells (APCs) but except:

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31)

Adjuvant used in HPV vaccine is:

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32)

Primary lymphoid organs include

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33)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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34)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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35)

In the application Antigen- Antibody reaction, which one is correct?

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36)

All are examples of names of monoclonal antibodies but except one?

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37)

Which of the following statement is true

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38)

An epitope is:

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39)

The characteristic of antigen-antibody interactions occur in second stage:

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40)

Which antibody is the first to be released into the blood following an infection?

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41)

An immunoglobulin is a:

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42)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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43)

The Follicular Dendritic Cells (FDCs) is located in:

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44)

Mode of IPV vaccine administration is:

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45)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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46)

Antigen presenting cells for vaccine are:

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47)

The following statements are the use of passive immunization included but except one?

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48)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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49)

The immunoglobulins transport across placenta mostly:

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50)

In the application Antigen- Antibody reaction, which one is correct?

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51)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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52)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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53)

The general principle of vaccination was established by:

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54)

The bonds involved in antigen-antibody interactions are

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55)

The immunoglobulins participated in complement system formation are:

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56)

The immune cells that is linked between innate and adaptive immunity are:

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57)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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58)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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59)

The naive T cells are:

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60)

Newborns get their antibodies from mother’s milk. This is an example of?

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61)

Which of the following is a polysaccharide vaccine:

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62)

An epitope:

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63)

The purpose of clinical trial of a vaccine is:

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64)

The first recombinant antigen vaccine approved for human use is:

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65)

The adverse effects of vaccines are linked to:

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66)

All are factors influencing in immunogenicity but except:

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67)

The class II MHC molecule appeared to bind with receptor of:

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68)

What vaccine should be avoided for the pregnant woman?

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69)

All are mechanism of action of complement but except:

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70)

Adjuvant used in HBV vaccine is:

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71)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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72)

The circulation of a two month old breast-fed baby will contain maternal:

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73)

All are immune cells in innate immune system but except:

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74)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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75)

Which of the following is not the function of antibody?

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76)

The following statements are criteria for a good vaccine but which is incorrect statement?

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77)

Which of the following is not an ideal property of a vaccine?

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78)

What is a live attenuated vaccine?

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79)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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80)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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81)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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82)

All are 3 main effects of complement but except:

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83)

The effectiveness is:

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84)

Natural humoral immune response against a pathogen leads to the production of:

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85)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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86)

Small chemical groups on the antigen molecule that can react with antibody

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87)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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88)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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89)

Which of the following statement is true regarding vaccination:

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90)

The complement system are synthesized by:

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91)

The classical pathway of complement activation is:

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92)

What is the mode of administration for anti-measles vaccine?

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93)

The antigen-antibody interactions occur in:

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94)

Graft and tumor rejection are mediated primarily by:

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95)

All are functions of immunoglobulins but except:

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96)

The immune cells that is linked between innate and adaptive immunity are:

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97)

In the application Antigen- Antibody reaction, which one is correct?

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98)

In order to elicit an immune response, a carbohydrate must be which of the following?

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99)

All are important characteristics of innate immunity but except:

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100)

All the following comes under non-specific defence mechanism except

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101)

Injection of immunoglobulin is:

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102)

Which of the following statements are true regarding polio vaccines:

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103)

Serum which contains antibodies is called:

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104)

The complement system consists of about:

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105)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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106)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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107)

The characteristic of antigen-antibody interactions occur in primary stage:

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108)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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109)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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110)

All are the measure for post rabies exposure prophylaxis, but except one?

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111)

The process of weakening a pathogen is called:

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112)

The complement system involved in phagocytic function are:

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113)

The complement system involved in chemotaxis are:

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114)

The class I MHC molecule appeared to bind with receptor of:

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115)

The main advantage of passive immunization over active immunization is that:

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116)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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117)

Which of the following antibodies have a positive effect on babies through breast feeding?

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118)

What vaccine can be used for pregnant women?

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119)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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120)

Tetanus toxoid is usually given to humans:

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121)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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122)

The technology used for the production of monoclonal antibodies is:

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123)

The efficacy is:

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124)

Which of the following is the site of T cell maturation?

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125)

The role of the macrophage during an antibody response is to:

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126)

In the application Antigen- Antibody reaction, which one is not correct?

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127)

All the given vaccines are attenuated or inactivated whole pathogen except:

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128)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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129)

The classical pathway of complement activation is:

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130)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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