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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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2)

All are important characteristics of innate immunity but except:

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3)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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4)

All are examples of names of monoclonal antibodies but except one?

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5)

The effectiveness is:

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6)

The antigen-antibody interactions occur in:

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7)

The class II MHC molecule appeared to bind with receptor of:

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8)

Graft and tumor rejection are mediated primarily by:

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9)

In the application Antigen- Antibody reaction, which one is correct?

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10)

Successful immunization can be impaired by:

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11)

What is the mode of administration for PCV-13 vaccine?

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12)

All are mechanism of action of complement but except:

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13)

All are functions of immunoglobulins but except:

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14)

The immunoglobulins transport across epithelium:

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15)

Infectious material from what illness was used to develop the first vaccine?

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16)

The main advantage of passive immunization over active immunization is that:

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17)

Which of the following is not an ideal property of a vaccine?

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18)

Natural humoral immune response against a pathogen leads to the production of:

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19)

The immune cells that is linked between innate and adaptive immunity are:

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20)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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21)

The complement system involved in the inflammation are:

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22)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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23)

An antigen is:

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24)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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25)

Immunogen is:

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26)

All are the measure for post rabies exposure prophylaxis, but except one?

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27)

All are immune cells in innate immune system but except:

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28)

The class I MHC molecule appeared to bind with receptor of:

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29)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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30)

The antibody-binding site is formed primarily by:

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31)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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32)

The impact is:

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33)

The following statements are the use of passive immunization included but except one?

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34)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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35)

The technology used for the production of monoclonal antibodies is:

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36)

The circulation of a two month old breast-fed baby will contain maternal:

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37)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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38)

The naive T cells are:

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39)

The bonds involved in antigen-antibody interactions are

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40)

An epitope:

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41)

The classical pathway of complement activation is:

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42)

In the application Antigen- Antibody reaction, which one is correct?

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43)

Vaccination is an example of?

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44)

The complement system involved in phagocytic function are:

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45)

Small chemical groups on the antigen molecule that can react with antibody

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46)

The immunoglobulins participated in complement system formation are:

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47)

The immune cells that is linked between innate and adaptive immunity are:

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48)

Which of the following antibody types forms a pentamer?

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49)

Which of the following statement is true

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50)

Adjuvant used in HPV vaccine is:

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51)

Which of the following is a polysaccharide vaccine:

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52)

All are therapeutic applications of polyclonal antibodies but except one?

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53)

The Follicular Dendritic Cells (FDCs) is located in:

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54)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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55)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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56)

Which of the following is not the function of antibody?

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57)

The characteristic of antigen-antibody interactions occur in primary stage:

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58)

Which of the following antibodies have a positive effect on babies through breast feeding?

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59)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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60)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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61)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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62)

What is a live attenuated vaccine?

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63)

In order to elicit an immune response, a carbohydrate must be which of the following?

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64)

Injection of immunoglobulin is:

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65)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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66)

Several of the complement components are:

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67)

In an immune response the type of cell which gets activated earliest is:

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68)

The complement system are synthesized by:

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69)

Which of the following statement is true regarding vaccination:

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70)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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71)

The cytotoxic T-cells is involved in:

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72)

Antigen presenting cells for vaccine are:

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73)

The immunoglobulins transport across placenta mostly:

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74)

The adverse effects of vaccines are linked to:

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75)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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76)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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77)

What vaccine should be avoided for the pregnant woman?

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78)

The type of T-cells that destroy host cells bearing foreign antigen:

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79)

In the application Antigen- Antibody reaction, which one is not correct?

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80)

The complement system involved in chemotaxis are:

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81)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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82)

All are factors influencing in immunogenicity but except:

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83)

The following statements are criteria for a good vaccine but which is incorrect statement?

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84)

The first recombinant antigen vaccine approved for human use is:

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85)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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86)

In the application Antigen- Antibody reaction, which one is correct?

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87)

The classical pathway of complement activation is:

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88)

Adjuvant used in HBV vaccine is:

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89)

All the given vaccines are attenuated or inactivated whole pathogen except:

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90)

Newborns get their antibodies from mother’s milk. This is an example of?

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91)

The general principle of vaccination was established by:

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92)

The herd immunity is:

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93)

All the following comes under non-specific defence mechanism except

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94)

Which of the following is the site of T cell maturation?

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95)

Tetanus toxoid is usually given to humans:

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96)

The first line of defense against invading pathogens:

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97)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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98)

Serum which contains antibodies is called:

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99)

All are 3 main effects of complement but except:

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100)

What is the mode of administration for anti-measles vaccine?

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101)

The role of the macrophage during an antibody response is to:

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102)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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103)

What vaccine can be used for pregnant women?

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104)

What is the mode of administration for BCG vaccine?

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105)

An epitope is:

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106)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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107)

All are Antigen-Presenting Cells (APCs) but except:

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108)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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109)

The Adverse events following immunization (AEFI) are divided into:

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110)

The process of weakening a pathogen is called:

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111)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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112)

The efficacy is:

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113)

Mode of IPV vaccine administration is:

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114)

Which antibody is the first to be released into the blood following an infection?

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115)

The purpose of clinical trial of a vaccine is:

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116)

What vaccine should not be frozen:

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117)

Primary lymphoid organs include

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118)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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119)

An immunoglobulin is a:

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120)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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121)

The complement system consists of about:

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122)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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123)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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124)

The characteristic of antigen-antibody interactions occur in second stage:

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125)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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126)

Which of the following statements are true regarding polio vaccines:

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127)

Injection of anti-venom to a patient for snake bite is example of?

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128)

What is the immune cell in adaptive immunity?

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129)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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130)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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