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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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2)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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3)

In an immune response the type of cell which gets activated earliest is:

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4)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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5)

In the application Antigen- Antibody reaction, which one is correct?

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6)

Vaccination is an example of?

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7)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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8)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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9)

The antibody-binding site is formed primarily by:

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10)

The antigen-antibody interactions occur in:

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11)

What is the immune cell in adaptive immunity?

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12)

The Adverse events following immunization (AEFI) are divided into:

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13)

Primary lymphoid organs include

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14)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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15)

In order to elicit an immune response, a carbohydrate must be which of the following?

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16)

The general principle of vaccination was established by:

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17)

What is the mode of administration for BCG vaccine?

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18)

All are functions of immunoglobulins but except:

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19)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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20)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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21)

Mode of IPV vaccine administration is:

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22)

The complement system are synthesized by:

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23)

Graft and tumor rejection are mediated primarily by:

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24)

Which of the following statements are true regarding polio vaccines:

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25)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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26)

Newborns get their antibodies from mother’s milk. This is an example of?

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27)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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28)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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29)

Small chemical groups on the antigen molecule that can react with antibody

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30)

The first recombinant antigen vaccine approved for human use is:

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31)

The class II MHC molecule appeared to bind with receptor of:

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32)

Adjuvant used in HPV vaccine is:

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33)

All are factors influencing in immunogenicity but except:

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34)

What vaccine should be avoided for the pregnant woman?

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35)

The bonds involved in antigen-antibody interactions are

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36)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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37)

Which antibody is the first to be released into the blood following an infection?

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38)

The complement system involved in phagocytic function are:

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39)

Which of the following is a polysaccharide vaccine:

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40)

Natural humoral immune response against a pathogen leads to the production of:

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41)

Injection of anti-venom to a patient for snake bite is example of?

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42)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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43)

The main advantage of passive immunization over active immunization is that:

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44)

In the application Antigen- Antibody reaction, which one is not correct?

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45)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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46)

What is the mode of administration for PCV-13 vaccine?

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47)

Serum which contains antibodies is called:

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48)

What vaccine should not be frozen:

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49)

All are the measure for post rabies exposure prophylaxis, but except one?

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50)

Which of the following is the site of T cell maturation?

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51)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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52)

The complement system involved in the inflammation are:

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53)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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54)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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55)

The following statements are the use of passive immunization included but except one?

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56)

The immunoglobulins transport across placenta mostly:

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57)

What is the mode of administration for anti-measles vaccine?

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58)

The immunoglobulins transport across epithelium:

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59)

Which of the following is not an ideal property of a vaccine?

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60)

Which of the following is not the function of antibody?

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61)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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62)

The effectiveness is:

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63)

The Follicular Dendritic Cells (FDCs) is located in:

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64)

Antigen presenting cells for vaccine are:

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65)

All are immune cells in innate immune system but except:

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66)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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67)

An epitope is:

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68)

All are Antigen-Presenting Cells (APCs) but except:

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69)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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70)

Tetanus toxoid is usually given to humans:

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71)

All are mechanism of action of complement but except:

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72)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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73)

Adjuvant used in HBV vaccine is:

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74)

Which of the following statement is true

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75)

The circulation of a two month old breast-fed baby will contain maternal:

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76)

All are 3 main effects of complement but except:

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77)

Infectious material from what illness was used to develop the first vaccine?

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78)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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79)

An immunoglobulin is a:

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80)

What is a live attenuated vaccine?

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81)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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82)

The technology used for the production of monoclonal antibodies is:

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83)

The herd immunity is:

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84)

An antigen is:

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85)

Immunogen is:

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86)

An epitope:

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87)

The classical pathway of complement activation is:

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88)

The immune cells that is linked between innate and adaptive immunity are:

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89)

The following statements are criteria for a good vaccine but which is incorrect statement?

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90)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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91)

The purpose of clinical trial of a vaccine is:

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92)

The type of T-cells that destroy host cells bearing foreign antigen:

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93)

Injection of immunoglobulin is:

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94)

The efficacy is:

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95)

The process of weakening a pathogen is called:

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96)

What vaccine can be used for pregnant women?

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97)

The cytotoxic T-cells is involved in:

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98)

Which of the following antibody types forms a pentamer?

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99)

All are examples of names of monoclonal antibodies but except one?

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100)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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101)

Several of the complement components are:

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102)

Which of the following antibodies have a positive effect on babies through breast feeding?

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103)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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104)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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105)

The naive T cells are:

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106)

The role of the macrophage during an antibody response is to:

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107)

Successful immunization can be impaired by:

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108)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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109)

The characteristic of antigen-antibody interactions occur in second stage:

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110)

The characteristic of antigen-antibody interactions occur in primary stage:

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111)

The immune cells that is linked between innate and adaptive immunity are:

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112)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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113)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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114)

All are therapeutic applications of polyclonal antibodies but except one?

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115)

All the given vaccines are attenuated or inactivated whole pathogen except:

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116)

The first line of defense against invading pathogens:

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117)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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118)

The adverse effects of vaccines are linked to:

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119)

All the following comes under non-specific defence mechanism except

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120)

The impact is:

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121)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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122)

The immunoglobulins participated in complement system formation are:

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123)

In the application Antigen- Antibody reaction, which one is correct?

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124)

All are important characteristics of innate immunity but except:

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125)

The classical pathway of complement activation is:

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126)

In the application Antigen- Antibody reaction, which one is correct?

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127)

The complement system consists of about:

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128)

The class I MHC molecule appeared to bind with receptor of:

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129)

Which of the following statement is true regarding vaccination:

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130)

The complement system involved in chemotaxis are:

Your score is

The average score is 58%

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