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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Which of the following is not an ideal property of a vaccine?

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2)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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3)

What is the mode of administration for anti-measles vaccine?

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4)

Which of the following is a polysaccharide vaccine:

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5)

An epitope is:

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6)

Injection of immunoglobulin is:

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7)

Several of the complement components are:

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8)

What is a live attenuated vaccine?

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9)

All are 3 main effects of complement but except:

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10)

Which of the following statement is true

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11)

The technology used for the production of monoclonal antibodies is:

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12)

All are immune cells in innate immune system but except:

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13)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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14)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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15)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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16)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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17)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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18)

The complement system involved in the inflammation are:

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19)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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20)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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21)

Which of the following antibody types forms a pentamer?

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22)

Graft and tumor rejection are mediated primarily by:

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23)

The main advantage of passive immunization over active immunization is that:

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24)

The first line of defense against invading pathogens:

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25)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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26)

Infectious material from what illness was used to develop the first vaccine?

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27)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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28)

The characteristic of antigen-antibody interactions occur in primary stage:

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29)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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30)

The complement system involved in phagocytic function are:

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31)

Tetanus toxoid is usually given to humans:

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32)

The adverse effects of vaccines are linked to:

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33)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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34)

The complement system involved in chemotaxis are:

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35)

All are important characteristics of innate immunity but except:

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36)

All are Antigen-Presenting Cells (APCs) but except:

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37)

The role of the macrophage during an antibody response is to:

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38)

In an immune response the type of cell which gets activated earliest is:

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39)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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40)

In the application Antigen- Antibody reaction, which one is correct?

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41)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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42)

The effectiveness is:

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43)

Which of the following statement is true regarding vaccination:

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44)

In the application Antigen- Antibody reaction, which one is correct?

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45)

All are the measure for post rabies exposure prophylaxis, but except one?

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46)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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47)

All the given vaccines are attenuated or inactivated whole pathogen except:

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48)

Small chemical groups on the antigen molecule that can react with antibody

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49)

What vaccine should not be frozen:

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50)

The immunoglobulins participated in complement system formation are:

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51)

The classical pathway of complement activation is:

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52)

The purpose of clinical trial of a vaccine is:

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53)

What vaccine should be avoided for the pregnant woman?

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54)

In the application Antigen- Antibody reaction, which one is not correct?

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55)

The general principle of vaccination was established by:

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56)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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57)

Which of the following is the site of T cell maturation?

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58)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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59)

All are factors influencing in immunogenicity but except:

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60)

Adjuvant used in HBV vaccine is:

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61)

The class II MHC molecule appeared to bind with receptor of:

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62)

Successful immunization can be impaired by:

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63)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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64)

The efficacy is:

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65)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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66)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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67)

In order to elicit an immune response, a carbohydrate must be which of the following?

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68)

The class I MHC molecule appeared to bind with receptor of:

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69)

The process of weakening a pathogen is called:

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70)

The immune cells that is linked between innate and adaptive immunity are:

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71)

The classical pathway of complement activation is:

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72)

In the application Antigen- Antibody reaction, which one is correct?

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73)

All are therapeutic applications of polyclonal antibodies but except one?

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74)

Mode of IPV vaccine administration is:

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75)

The type of T-cells that destroy host cells bearing foreign antigen:

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76)

The following statements are criteria for a good vaccine but which is incorrect statement?

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77)

Which of the following is not the function of antibody?

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78)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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79)

All are functions of immunoglobulins but except:

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80)

An epitope:

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81)

The impact is:

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82)

Newborns get their antibodies from mother’s milk. This is an example of?

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83)

The immunoglobulins transport across epithelium:

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84)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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85)

The naive T cells are:

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86)

An immunoglobulin is a:

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87)

The herd immunity is:

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88)

The antibody-binding site is formed primarily by:

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89)

Natural humoral immune response against a pathogen leads to the production of:

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90)

Adjuvant used in HPV vaccine is:

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91)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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92)

The immune cells that is linked between innate and adaptive immunity are:

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93)

Antigen presenting cells for vaccine are:

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94)

The characteristic of antigen-antibody interactions occur in second stage:

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95)

Serum which contains antibodies is called:

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96)

The antigen-antibody interactions occur in:

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97)

The circulation of a two month old breast-fed baby will contain maternal:

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98)

The complement system are synthesized by:

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99)

The first recombinant antigen vaccine approved for human use is:

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100)

The following statements are the use of passive immunization included but except one?

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101)

The Adverse events following immunization (AEFI) are divided into:

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102)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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103)

What is the mode of administration for PCV-13 vaccine?

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104)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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105)

The immunoglobulins transport across placenta mostly:

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106)

All the following comes under non-specific defence mechanism except

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107)

All are examples of names of monoclonal antibodies but except one?

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108)

The bonds involved in antigen-antibody interactions are

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109)

Which of the following antibodies have a positive effect on babies through breast feeding?

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110)

All are mechanism of action of complement but except:

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111)

The Follicular Dendritic Cells (FDCs) is located in:

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112)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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113)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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114)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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115)

Which antibody is the first to be released into the blood following an infection?

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116)

Vaccination is an example of?

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117)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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118)

What is the mode of administration for BCG vaccine?

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119)

Immunogen is:

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120)

The cytotoxic T-cells is involved in:

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121)

Injection of anti-venom to a patient for snake bite is example of?

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122)

An antigen is:

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123)

The complement system consists of about:

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124)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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125)

What is the immune cell in adaptive immunity?

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126)

What vaccine can be used for pregnant women?

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127)

Which of the following statements are true regarding polio vaccines:

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128)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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129)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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130)

Primary lymphoid organs include

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