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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Several of the complement components are:

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2)

Newborns get their antibodies from mother’s milk. This is an example of?

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3)

What vaccine should be avoided for the pregnant woman?

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4)

What is the mode of administration for PCV-13 vaccine?

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5)

All are immune cells in innate immune system but except:

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6)

Graft and tumor rejection are mediated primarily by:

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7)

What vaccine should not be frozen:

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8)

The circulation of a two month old breast-fed baby will contain maternal:

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9)

Which of the following statement is true

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10)

An immunoglobulin is a:

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11)

All are factors influencing in immunogenicity but except:

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12)

The type of T-cells that destroy host cells bearing foreign antigen:

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13)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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14)

What is a live attenuated vaccine?

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15)

What is the immune cell in adaptive immunity?

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16)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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17)

The immunoglobulins transport across placenta mostly:

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18)

Vaccination is an example of?

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19)

The complement system involved in chemotaxis are:

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20)

The first line of defense against invading pathogens:

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21)

Which of the following is not the function of antibody?

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22)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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23)

Serum which contains antibodies is called:

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24)

The immune cells that is linked between innate and adaptive immunity are:

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25)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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26)

The following statements are criteria for a good vaccine but which is incorrect statement?

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27)

The class II MHC molecule appeared to bind with receptor of:

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28)

Injection of immunoglobulin is:

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29)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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30)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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31)

Antigen presenting cells for vaccine are:

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32)

An epitope is:

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33)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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34)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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35)

All are functions of immunoglobulins but except:

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36)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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37)

Small chemical groups on the antigen molecule that can react with antibody

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38)

The antibody-binding site is formed primarily by:

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39)

Primary lymphoid organs include

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40)

The classical pathway of complement activation is:

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41)

An epitope:

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42)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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43)

The characteristic of antigen-antibody interactions occur in second stage:

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44)

The complement system involved in the inflammation are:

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45)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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46)

Which of the following is the site of T cell maturation?

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47)

All are mechanism of action of complement but except:

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48)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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49)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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50)

The complement system consists of about:

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51)

In the application Antigen- Antibody reaction, which one is correct?

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52)

All are the measure for post rabies exposure prophylaxis, but except one?

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53)

What vaccine can be used for pregnant women?

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54)

The bonds involved in antigen-antibody interactions are

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55)

Mode of IPV vaccine administration is:

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56)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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57)

Tetanus toxoid is usually given to humans:

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58)

All are examples of names of monoclonal antibodies but except one?

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59)

The characteristic of antigen-antibody interactions occur in primary stage:

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60)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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61)

The technology used for the production of monoclonal antibodies is:

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62)

All the given vaccines are attenuated or inactivated whole pathogen except:

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63)

Successful immunization can be impaired by:

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64)

What is the mode of administration for anti-measles vaccine?

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65)

The immune cells that is linked between innate and adaptive immunity are:

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66)

The complement system are synthesized by:

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67)

In the application Antigen- Antibody reaction, which one is correct?

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68)

The complement system involved in phagocytic function are:

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69)

The first recombinant antigen vaccine approved for human use is:

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70)

Adjuvant used in HPV vaccine is:

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71)

Which of the following is not an ideal property of a vaccine?

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72)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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73)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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74)

The role of the macrophage during an antibody response is to:

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75)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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76)

What is the mode of administration for BCG vaccine?

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77)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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78)

Which of the following statement is true regarding vaccination:

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79)

The classical pathway of complement activation is:

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80)

Injection of anti-venom to a patient for snake bite is example of?

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81)

Natural humoral immune response against a pathogen leads to the production of:

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82)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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83)

All are important characteristics of innate immunity but except:

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84)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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85)

The antigen-antibody interactions occur in:

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86)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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87)

The cytotoxic T-cells is involved in:

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88)

All are therapeutic applications of polyclonal antibodies but except one?

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89)

Which antibody is the first to be released into the blood following an infection?

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90)

The herd immunity is:

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91)

In the application Antigen- Antibody reaction, which one is not correct?

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92)

Immunogen is:

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93)

Infectious material from what illness was used to develop the first vaccine?

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94)

An antigen is:

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95)

The impact is:

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96)

The general principle of vaccination was established by:

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97)

All are 3 main effects of complement but except:

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98)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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99)

Adjuvant used in HBV vaccine is:

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100)

The class I MHC molecule appeared to bind with receptor of:

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101)

All the following comes under non-specific defence mechanism except

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102)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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103)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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104)

The immunoglobulins participated in complement system formation are:

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105)

In order to elicit an immune response, a carbohydrate must be which of the following?

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106)

Which of the following antibodies have a positive effect on babies through breast feeding?

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107)

The purpose of clinical trial of a vaccine is:

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108)

Which of the following statements are true regarding polio vaccines:

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109)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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110)

All are Antigen-Presenting Cells (APCs) but except:

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111)

Which of the following is a polysaccharide vaccine:

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112)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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113)

In an immune response the type of cell which gets activated earliest is:

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114)

The Adverse events following immunization (AEFI) are divided into:

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115)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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116)

The immunoglobulins transport across epithelium:

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117)

The Follicular Dendritic Cells (FDCs) is located in:

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118)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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119)

The main advantage of passive immunization over active immunization is that:

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120)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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121)

The adverse effects of vaccines are linked to:

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122)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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123)

The naive T cells are:

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124)

Which of the following antibody types forms a pentamer?

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125)

The following statements are the use of passive immunization included but except one?

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126)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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127)

The process of weakening a pathogen is called:

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128)

The efficacy is:

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129)

In the application Antigen- Antibody reaction, which one is correct?

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The effectiveness is:

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