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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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2)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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3)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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4)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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5)

Which of the following is not the function of antibody?

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6)

Tetanus toxoid is usually given to humans:

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7)

Which of the following is the site of T cell maturation?

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8)

In the application Antigen- Antibody reaction, which one is not correct?

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9)

The complement system consists of about:

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10)

The cytotoxic T-cells is involved in:

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11)

All are 3 main effects of complement but except:

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12)

In the application Antigen- Antibody reaction, which one is correct?

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13)

The complement system involved in the inflammation are:

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14)

The class I MHC molecule appeared to bind with receptor of:

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15)

What vaccine can be used for pregnant women?

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16)

The complement system involved in chemotaxis are:

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17)

The main advantage of passive immunization over active immunization is that:

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18)

The Follicular Dendritic Cells (FDCs) is located in:

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19)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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20)

The classical pathway of complement activation is:

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21)

The characteristic of antigen-antibody interactions occur in second stage:

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22)

Injection of anti-venom to a patient for snake bite is example of?

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23)

All the following comes under non-specific defence mechanism except

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24)

The process of weakening a pathogen is called:

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25)

Adjuvant used in HBV vaccine is:

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26)

The immunoglobulins transport across placenta mostly:

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27)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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28)

The purpose of clinical trial of a vaccine is:

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29)

Graft and tumor rejection are mediated primarily by:

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30)

All are mechanism of action of complement but except:

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31)

The first recombinant antigen vaccine approved for human use is:

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32)

The immunoglobulins participated in complement system formation are:

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33)

The bonds involved in antigen-antibody interactions are

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34)

What vaccine should not be frozen:

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35)

The herd immunity is:

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36)

The circulation of a two month old breast-fed baby will contain maternal:

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37)

Which of the following statement is true

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38)

All are the measure for post rabies exposure prophylaxis, but except one?

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39)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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40)

Which of the following is not an ideal property of a vaccine?

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41)

The role of the macrophage during an antibody response is to:

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42)

The following statements are the use of passive immunization included but except one?

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43)

All are factors influencing in immunogenicity but except:

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44)

Primary lymphoid organs include

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45)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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46)

Which of the following antibody types forms a pentamer?

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47)

Natural humoral immune response against a pathogen leads to the production of:

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48)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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49)

Which antibody is the first to be released into the blood following an infection?

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50)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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51)

The following statements are criteria for a good vaccine but which is incorrect statement?

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52)

Injection of immunoglobulin is:

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53)

Small chemical groups on the antigen molecule that can react with antibody

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54)

The general principle of vaccination was established by:

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55)

Which of the following is a polysaccharide vaccine:

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56)

Antigen presenting cells for vaccine are:

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57)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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58)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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59)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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60)

The effectiveness is:

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61)

All are functions of immunoglobulins but except:

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62)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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63)

The antigen-antibody interactions occur in:

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64)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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65)

Which of the following statement is true regarding vaccination:

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66)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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67)

The type of T-cells that destroy host cells bearing foreign antigen:

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68)

In the application Antigen- Antibody reaction, which one is correct?

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69)

All the given vaccines are attenuated or inactivated whole pathogen except:

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70)

Infectious material from what illness was used to develop the first vaccine?

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71)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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72)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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73)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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74)

Vaccination is an example of?

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75)

The efficacy is:

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76)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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77)

What vaccine should be avoided for the pregnant woman?

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78)

All are therapeutic applications of polyclonal antibodies but except one?

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79)

Newborns get their antibodies from mother’s milk. This is an example of?

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80)

An epitope:

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81)

The characteristic of antigen-antibody interactions occur in primary stage:

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82)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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83)

The immune cells that is linked between innate and adaptive immunity are:

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84)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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85)

An epitope is:

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86)

The technology used for the production of monoclonal antibodies is:

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87)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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88)

The class II MHC molecule appeared to bind with receptor of:

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89)

The Adverse events following immunization (AEFI) are divided into:

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90)

The adverse effects of vaccines are linked to:

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91)

The immune cells that is linked between innate and adaptive immunity are:

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92)

All are immune cells in innate immune system but except:

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93)

Serum which contains antibodies is called:

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94)

Mode of IPV vaccine administration is:

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95)

Several of the complement components are:

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96)

All are Antigen-Presenting Cells (APCs) but except:

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97)

The classical pathway of complement activation is:

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98)

The first line of defense against invading pathogens:

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99)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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100)

All are examples of names of monoclonal antibodies but except one?

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101)

An immunoglobulin is a:

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102)

Immunogen is:

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103)

In the application Antigen- Antibody reaction, which one is correct?

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104)

In order to elicit an immune response, a carbohydrate must be which of the following?

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105)

Successful immunization can be impaired by:

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106)

What is the mode of administration for PCV-13 vaccine?

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107)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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108)

The complement system are synthesized by:

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109)

In an immune response the type of cell which gets activated earliest is:

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110)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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111)

What is the immune cell in adaptive immunity?

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112)

Which of the following statements are true regarding polio vaccines:

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113)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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114)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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115)

The impact is:

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116)

The antibody-binding site is formed primarily by:

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117)

What is a live attenuated vaccine?

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118)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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119)

An antigen is:

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120)

All are important characteristics of innate immunity but except:

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121)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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122)

Adjuvant used in HPV vaccine is:

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123)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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124)

The immunoglobulins transport across epithelium:

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125)

The naive T cells are:

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126)

Which of the following antibodies have a positive effect on babies through breast feeding?

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127)

The complement system involved in phagocytic function are:

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128)

What is the mode of administration for anti-measles vaccine?

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129)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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130)

What is the mode of administration for BCG vaccine?

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