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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

The general principle of vaccination was established by:

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2)

What vaccine can be used for pregnant women?

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3)

In an immune response the type of cell which gets activated earliest is:

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4)

In the application Antigen- Antibody reaction, which one is correct?

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5)

The characteristic of antigen-antibody interactions occur in primary stage:

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6)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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7)

What is a live attenuated vaccine?

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8)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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9)

The process of weakening a pathogen is called:

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10)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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11)

All are 3 main effects of complement but except:

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12)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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13)

The naive T cells are:

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14)

All are important characteristics of innate immunity but except:

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15)

Successful immunization can be impaired by:

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16)

The herd immunity is:

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17)

Several of the complement components are:

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18)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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19)

Antigen presenting cells for vaccine are:

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20)

The antigen-antibody interactions occur in:

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21)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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22)

What is the mode of administration for BCG vaccine?

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23)

The complement system involved in chemotaxis are:

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24)

The circulation of a two month old breast-fed baby will contain maternal:

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25)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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26)

Which of the following is the site of T cell maturation?

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27)

The classical pathway of complement activation is:

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28)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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29)

All are Antigen-Presenting Cells (APCs) but except:

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30)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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31)

What is the mode of administration for PCV-13 vaccine?

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32)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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33)

Which of the following statement is true

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34)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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35)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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36)

Which of the following statement is true regarding vaccination:

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37)

An epitope is:

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38)

In the application Antigen- Antibody reaction, which one is correct?

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39)

All are therapeutic applications of polyclonal antibodies but except one?

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40)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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41)

The complement system involved in phagocytic function are:

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42)

Which of the following statements are true regarding polio vaccines:

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43)

What is the mode of administration for anti-measles vaccine?

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44)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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45)

Which of the following is not the function of antibody?

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46)

The immunoglobulins participated in complement system formation are:

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47)

All the following comes under non-specific defence mechanism except

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48)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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49)

Which of the following antibodies have a positive effect on babies through breast feeding?

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50)

Natural humoral immune response against a pathogen leads to the production of:

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51)

Graft and tumor rejection are mediated primarily by:

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52)

The Adverse events following immunization (AEFI) are divided into:

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53)

Adjuvant used in HBV vaccine is:

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54)

All the given vaccines are attenuated or inactivated whole pathogen except:

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55)

Injection of immunoglobulin is:

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56)

Which of the following antibody types forms a pentamer?

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57)

In the application Antigen- Antibody reaction, which one is not correct?

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58)

The main advantage of passive immunization over active immunization is that:

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59)

What vaccine should not be frozen:

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60)

The technology used for the production of monoclonal antibodies is:

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61)

Vaccination is an example of?

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62)

All are immune cells in innate immune system but except:

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63)

An immunoglobulin is a:

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64)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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65)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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66)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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67)

An epitope:

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68)

The cytotoxic T-cells is involved in:

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69)

The efficacy is:

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70)

Mode of IPV vaccine administration is:

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71)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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72)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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73)

Injection of anti-venom to a patient for snake bite is example of?

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74)

The type of T-cells that destroy host cells bearing foreign antigen:

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75)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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76)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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77)

The role of the macrophage during an antibody response is to:

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78)

The characteristic of antigen-antibody interactions occur in second stage:

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79)

The purpose of clinical trial of a vaccine is:

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80)

What is the immune cell in adaptive immunity?

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81)

The effectiveness is:

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82)

The adverse effects of vaccines are linked to:

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83)

The Follicular Dendritic Cells (FDCs) is located in:

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84)

An antigen is:

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85)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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86)

The impact is:

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87)

Serum which contains antibodies is called:

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88)

Which of the following is not an ideal property of a vaccine?

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89)

The complement system consists of about:

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90)

Which of the following is a polysaccharide vaccine:

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91)

Immunogen is:

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92)

The complement system involved in the inflammation are:

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93)

Primary lymphoid organs include

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94)

All are factors influencing in immunogenicity but except:

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95)

The class I MHC molecule appeared to bind with receptor of:

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96)

All are the measure for post rabies exposure prophylaxis, but except one?

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97)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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98)

The first recombinant antigen vaccine approved for human use is:

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99)

All are mechanism of action of complement but except:

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100)

Infectious material from what illness was used to develop the first vaccine?

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101)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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102)

The complement system are synthesized by:

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103)

The classical pathway of complement activation is:

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104)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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105)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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106)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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107)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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108)

The immunoglobulins transport across epithelium:

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109)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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110)

The class II MHC molecule appeared to bind with receptor of:

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111)

Adjuvant used in HPV vaccine is:

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112)

The immune cells that is linked between innate and adaptive immunity are:

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113)

Newborns get their antibodies from mother’s milk. This is an example of?

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114)

All are examples of names of monoclonal antibodies but except one?

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115)

The following statements are criteria for a good vaccine but which is incorrect statement?

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116)

Small chemical groups on the antigen molecule that can react with antibody

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117)

The bonds involved in antigen-antibody interactions are

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118)

Which antibody is the first to be released into the blood following an infection?

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119)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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120)

All are functions of immunoglobulins but except:

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121)

Tetanus toxoid is usually given to humans:

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122)

In the application Antigen- Antibody reaction, which one is correct?

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123)

The first line of defense against invading pathogens:

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124)

The immunoglobulins transport across placenta mostly:

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125)

The following statements are the use of passive immunization included but except one?

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126)

The antibody-binding site is formed primarily by:

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127)

What vaccine should be avoided for the pregnant woman?

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128)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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129)

The immune cells that is linked between innate and adaptive immunity are:

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130)

In order to elicit an immune response, a carbohydrate must be which of the following?

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