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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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2)

Which of the following is a polysaccharide vaccine:

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3)

Immunogen is:

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4)

The immunoglobulins transport across placenta mostly:

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5)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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6)

Infectious material from what illness was used to develop the first vaccine?

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7)

The purpose of clinical trial of a vaccine is:

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8)

An epitope:

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9)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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10)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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11)

Natural humoral immune response against a pathogen leads to the production of:

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12)

Injection of anti-venom to a patient for snake bite is example of?

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13)

An antigen is:

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14)

The type of T-cells that destroy host cells bearing foreign antigen:

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15)

The process of weakening a pathogen is called:

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16)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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17)

Successful immunization can be impaired by:

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18)

The first line of defense against invading pathogens:

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19)

Small chemical groups on the antigen molecule that can react with antibody

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20)

Newborns get their antibodies from mother’s milk. This is an example of?

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21)

Injection of immunoglobulin is:

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22)

In the application Antigen- Antibody reaction, which one is correct?

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23)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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24)

Serum which contains antibodies is called:

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25)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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26)

The class II MHC molecule appeared to bind with receptor of:

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27)

The main advantage of passive immunization over active immunization is that:

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28)

The first recombinant antigen vaccine approved for human use is:

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29)

The immune cells that is linked between innate and adaptive immunity are:

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30)

All are 3 main effects of complement but except:

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31)

The complement system involved in the inflammation are:

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32)

The complement system involved in phagocytic function are:

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33)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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34)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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35)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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36)

What is the immune cell in adaptive immunity?

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37)

The general principle of vaccination was established by:

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38)

The bonds involved in antigen-antibody interactions are

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39)

The efficacy is:

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40)

Primary lymphoid organs include

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41)

The antibody-binding site is formed primarily by:

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42)

The complement system are synthesized by:

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43)

What vaccine can be used for pregnant women?

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44)

Graft and tumor rejection are mediated primarily by:

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45)

Which of the following statement is true

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46)

All are Antigen-Presenting Cells (APCs) but except:

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47)

All are examples of names of monoclonal antibodies but except one?

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48)

Which of the following is not the function of antibody?

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49)

Which of the following antibody types forms a pentamer?

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50)

All are therapeutic applications of polyclonal antibodies but except one?

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51)

The technology used for the production of monoclonal antibodies is:

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52)

In an immune response the type of cell which gets activated earliest is:

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53)

All are functions of immunoglobulins but except:

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54)

The class I MHC molecule appeared to bind with receptor of:

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55)

In the application Antigen- Antibody reaction, which one is correct?

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56)

What vaccine should be avoided for the pregnant woman?

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57)

The following statements are the use of passive immunization included but except one?

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58)

All are immune cells in innate immune system but except:

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59)

Adjuvant used in HPV vaccine is:

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60)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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61)

The immunoglobulins participated in complement system formation are:

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The impact is:

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63)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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64)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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65)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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66)

In order to elicit an immune response, a carbohydrate must be which of the following?

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67)

All are important characteristics of innate immunity but except:

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68)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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69)

The immunoglobulins transport across epithelium:

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70)

The characteristic of antigen-antibody interactions occur in primary stage:

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71)

All are factors influencing in immunogenicity but except:

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72)

The role of the macrophage during an antibody response is to:

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73)

Which of the following is the site of T cell maturation?

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74)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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75)

An epitope is:

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76)

What is the mode of administration for PCV-13 vaccine?

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77)

Vaccination is an example of?

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78)

Which of the following antibodies have a positive effect on babies through breast feeding?

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79)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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80)

Which of the following statements are true regarding polio vaccines:

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81)

In the application Antigen- Antibody reaction, which one is correct?

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82)

Adjuvant used in HBV vaccine is:

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83)

All are the measure for post rabies exposure prophylaxis, but except one?

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84)

The cytotoxic T-cells is involved in:

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85)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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86)

Which antibody is the first to be released into the blood following an infection?

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87)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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88)

What is the mode of administration for BCG vaccine?

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89)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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90)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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91)

Which of the following statement is true regarding vaccination:

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92)

The effectiveness is:

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93)

The complement system consists of about:

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94)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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95)

An immunoglobulin is a:

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96)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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97)

The classical pathway of complement activation is:

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98)

In the application Antigen- Antibody reaction, which one is not correct?

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99)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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100)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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101)

The circulation of a two month old breast-fed baby will contain maternal:

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102)

Tetanus toxoid is usually given to humans:

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103)

What vaccine should not be frozen:

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104)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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105)

What is the mode of administration for anti-measles vaccine?

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106)

The immune cells that is linked between innate and adaptive immunity are:

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107)

The following statements are criteria for a good vaccine but which is incorrect statement?

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108)

All are mechanism of action of complement but except:

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109)

The characteristic of antigen-antibody interactions occur in second stage:

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110)

The Follicular Dendritic Cells (FDCs) is located in:

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111)

Antigen presenting cells for vaccine are:

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112)

The naive T cells are:

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113)

All the given vaccines are attenuated or inactivated whole pathogen except:

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114)

The complement system involved in chemotaxis are:

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115)

The Adverse events following immunization (AEFI) are divided into:

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116)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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117)

The antigen-antibody interactions occur in:

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118)

All the following comes under non-specific defence mechanism except

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119)

The adverse effects of vaccines are linked to:

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120)

Several of the complement components are:

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121)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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122)

The classical pathway of complement activation is:

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123)

What is a live attenuated vaccine?

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124)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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125)

Which of the following is not an ideal property of a vaccine?

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126)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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Mode of IPV vaccine administration is:

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128)

The herd immunity is:

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129)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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