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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

In order to elicit an immune response, a carbohydrate must be which of the following?

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2)

Which of the following statement is true

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3)

The immunoglobulins transport across placenta mostly:

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4)

The antigen-antibody interactions occur in:

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5)

Which of the following antibody types forms a pentamer?

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6)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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7)

All are 3 main effects of complement but except:

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8)

In the application Antigen- Antibody reaction, which one is correct?

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9)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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10)

Antigen presenting cells for vaccine are:

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11)

What is the mode of administration for PCV-13 vaccine?

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12)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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13)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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14)

Small chemical groups on the antigen molecule that can react with antibody

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15)

The following statements are the use of passive immunization included but except one?

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16)

The complement system consists of about:

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17)

The first line of defense against invading pathogens:

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18)

Which of the following is the site of T cell maturation?

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19)

An immunoglobulin is a:

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20)

Which antibody is the first to be released into the blood following an infection?

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21)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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22)

The naive T cells are:

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23)

The efficacy is:

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24)

The bonds involved in antigen-antibody interactions are

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25)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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26)

The herd immunity is:

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27)

All are Antigen-Presenting Cells (APCs) but except:

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28)

All are immune cells in innate immune system but except:

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29)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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30)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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31)

The characteristic of antigen-antibody interactions occur in primary stage:

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32)

Newborns get their antibodies from mother’s milk. This is an example of?

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33)

The classical pathway of complement activation is:

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34)

Serum which contains antibodies is called:

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35)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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36)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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37)

What vaccine should not be frozen:

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38)

The process of weakening a pathogen is called:

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39)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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40)

All the given vaccines are attenuated or inactivated whole pathogen except:

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41)

The cytotoxic T-cells is involved in:

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42)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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43)

Which of the following statements are true regarding polio vaccines:

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44)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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45)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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46)

In the application Antigen- Antibody reaction, which one is correct?

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47)

Infectious material from what illness was used to develop the first vaccine?

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48)

The complement system involved in chemotaxis are:

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49)

Which of the following is not an ideal property of a vaccine?

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50)

What is a live attenuated vaccine?

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51)

Injection of anti-venom to a patient for snake bite is example of?

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52)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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53)

What is the mode of administration for anti-measles vaccine?

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54)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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55)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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56)

The following statements are criteria for a good vaccine but which is incorrect statement?

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57)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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58)

Natural humoral immune response against a pathogen leads to the production of:

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59)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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60)

Which of the following is not the function of antibody?

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61)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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62)

What vaccine should be avoided for the pregnant woman?

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63)

What vaccine can be used for pregnant women?

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64)

All are examples of names of monoclonal antibodies but except one?

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65)

The class II MHC molecule appeared to bind with receptor of:

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66)

All are important characteristics of innate immunity but except:

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67)

In an immune response the type of cell which gets activated earliest is:

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68)

All are the measure for post rabies exposure prophylaxis, but except one?

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69)

All are factors influencing in immunogenicity but except:

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70)

The general principle of vaccination was established by:

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71)

The immunoglobulins transport across epithelium:

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72)

The first recombinant antigen vaccine approved for human use is:

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73)

Which of the following is a polysaccharide vaccine:

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74)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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75)

Graft and tumor rejection are mediated primarily by:

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76)

Adjuvant used in HPV vaccine is:

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77)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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78)

Mode of IPV vaccine administration is:

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79)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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80)

The immune cells that is linked between innate and adaptive immunity are:

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81)

The role of the macrophage during an antibody response is to:

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82)

The type of T-cells that destroy host cells bearing foreign antigen:

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83)

The Follicular Dendritic Cells (FDCs) is located in:

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84)

The classical pathway of complement activation is:

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85)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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86)

What is the mode of administration for BCG vaccine?

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87)

Tetanus toxoid is usually given to humans:

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88)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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89)

The characteristic of antigen-antibody interactions occur in second stage:

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90)

The technology used for the production of monoclonal antibodies is:

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91)

What is the immune cell in adaptive immunity?

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92)

The purpose of clinical trial of a vaccine is:

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93)

The complement system are synthesized by:

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94)

Injection of immunoglobulin is:

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95)

All are functions of immunoglobulins but except:

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96)

Vaccination is an example of?

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97)

Primary lymphoid organs include

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98)

An epitope is:

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99)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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100)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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101)

The impact is:

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102)

The immune cells that is linked between innate and adaptive immunity are:

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103)

The main advantage of passive immunization over active immunization is that:

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104)

The class I MHC molecule appeared to bind with receptor of:

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105)

The antibody-binding site is formed primarily by:

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106)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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107)

Immunogen is:

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108)

The circulation of a two month old breast-fed baby will contain maternal:

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109)

The complement system involved in phagocytic function are:

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110)

The adverse effects of vaccines are linked to:

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111)

In the application Antigen- Antibody reaction, which one is not correct?

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112)

In the application Antigen- Antibody reaction, which one is correct?

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113)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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114)

Several of the complement components are:

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115)

The Adverse events following immunization (AEFI) are divided into:

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116)

All are therapeutic applications of polyclonal antibodies but except one?

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117)

An epitope:

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118)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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119)

The effectiveness is:

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120)

An antigen is:

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121)

Adjuvant used in HBV vaccine is:

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122)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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123)

All the following comes under non-specific defence mechanism except

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124)

The complement system involved in the inflammation are:

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125)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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126)

All are mechanism of action of complement but except:

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127)

Successful immunization can be impaired by:

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128)

Which of the following statement is true regarding vaccination:

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129)

Which of the following antibodies have a positive effect on babies through breast feeding?

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130)

The immunoglobulins participated in complement system formation are:

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