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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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2)

The impact is:

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3)

An immunoglobulin is a:

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4)

The antibody-binding site is formed primarily by:

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5)

Adjuvant used in HPV vaccine is:

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6)

The class I MHC molecule appeared to bind with receptor of:

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7)

The immune cells that is linked between innate and adaptive immunity are:

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8)

The classical pathway of complement activation is:

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9)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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10)

Successful immunization can be impaired by:

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11)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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12)

Which of the following statements are true regarding polio vaccines:

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13)

In the application Antigen- Antibody reaction, which one is correct?

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14)

The circulation of a two month old breast-fed baby will contain maternal:

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15)

The following statements are criteria for a good vaccine but which is incorrect statement?

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16)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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17)

The efficacy is:

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18)

Which of the following is a polysaccharide vaccine:

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19)

The antigen-antibody interactions occur in:

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20)

Injection of immunoglobulin is:

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21)

An epitope:

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22)

What vaccine should not be frozen:

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23)

The type of T-cells that destroy host cells bearing foreign antigen:

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24)

All the given vaccines are attenuated or inactivated whole pathogen except:

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25)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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26)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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27)

The classical pathway of complement activation is:

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28)

Immunogen is:

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29)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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30)

The bonds involved in antigen-antibody interactions are

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31)

What is the mode of administration for BCG vaccine?

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32)

All are important characteristics of innate immunity but except:

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33)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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34)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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35)

Which of the following is the site of T cell maturation?

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36)

The role of the macrophage during an antibody response is to:

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37)

Tetanus toxoid is usually given to humans:

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38)

The complement system involved in the inflammation are:

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39)

All are examples of names of monoclonal antibodies but except one?

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40)

The complement system involved in phagocytic function are:

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41)

What is the immune cell in adaptive immunity?

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42)

The class II MHC molecule appeared to bind with receptor of:

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43)

The technology used for the production of monoclonal antibodies is:

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44)

Serum which contains antibodies is called:

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45)

The herd immunity is:

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46)

The naive T cells are:

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47)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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48)

Small chemical groups on the antigen molecule that can react with antibody

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49)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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50)

Infectious material from what illness was used to develop the first vaccine?

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51)

Several of the complement components are:

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52)

The process of weakening a pathogen is called:

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53)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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54)

Adjuvant used in HBV vaccine is:

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55)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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56)

The immune cells that is linked between innate and adaptive immunity are:

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57)

In order to elicit an immune response, a carbohydrate must be which of the following?

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58)

All are factors influencing in immunogenicity but except:

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59)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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60)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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61)

The Adverse events following immunization (AEFI) are divided into:

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62)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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63)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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64)

Newborns get their antibodies from mother’s milk. This is an example of?

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65)

What vaccine can be used for pregnant women?

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66)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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67)

Graft and tumor rejection are mediated primarily by:

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68)

Antigen presenting cells for vaccine are:

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69)

Which of the following antibodies have a positive effect on babies through breast feeding?

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70)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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71)

Vaccination is an example of?

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72)

All are the measure for post rabies exposure prophylaxis, but except one?

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73)

The general principle of vaccination was established by:

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74)

In the application Antigen- Antibody reaction, which one is correct?

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75)

The following statements are the use of passive immunization included but except one?

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76)

What vaccine should be avoided for the pregnant woman?

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77)

All the following comes under non-specific defence mechanism except

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78)

The effectiveness is:

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79)

Which of the following antibody types forms a pentamer?

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80)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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81)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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82)

The complement system are synthesized by:

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83)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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84)

What is the mode of administration for PCV-13 vaccine?

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85)

Primary lymphoid organs include

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86)

The cytotoxic T-cells is involved in:

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87)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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88)

The main advantage of passive immunization over active immunization is that:

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89)

Injection of anti-venom to a patient for snake bite is example of?

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90)

Mode of IPV vaccine administration is:

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91)

The immunoglobulins transport across placenta mostly:

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92)

All are therapeutic applications of polyclonal antibodies but except one?

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93)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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94)

What is a live attenuated vaccine?

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95)

Which of the following is not an ideal property of a vaccine?

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96)

Which of the following statement is true regarding vaccination:

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97)

An antigen is:

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98)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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99)

Which of the following statement is true

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100)

The Follicular Dendritic Cells (FDCs) is located in:

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101)

The complement system consists of about:

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102)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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103)

The characteristic of antigen-antibody interactions occur in second stage:

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104)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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105)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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106)

The adverse effects of vaccines are linked to:

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107)

The complement system involved in chemotaxis are:

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108)

The immunoglobulins participated in complement system formation are:

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109)

In the application Antigen- Antibody reaction, which one is not correct?

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110)

The first recombinant antigen vaccine approved for human use is:

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111)

All are functions of immunoglobulins but except:

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112)

Which of the following is not the function of antibody?

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113)

Which antibody is the first to be released into the blood following an infection?

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114)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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115)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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116)

In the application Antigen- Antibody reaction, which one is correct?

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117)

The immunoglobulins transport across epithelium:

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118)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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119)

In an immune response the type of cell which gets activated earliest is:

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120)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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121)

An epitope is:

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122)

All are 3 main effects of complement but except:

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123)

All are Antigen-Presenting Cells (APCs) but except:

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124)

The first line of defense against invading pathogens:

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125)

What is the mode of administration for anti-measles vaccine?

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126)

The purpose of clinical trial of a vaccine is:

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127)

Natural humoral immune response against a pathogen leads to the production of:

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128)

All are immune cells in innate immune system but except:

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129)

The characteristic of antigen-antibody interactions occur in primary stage:

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130)

All are mechanism of action of complement but except:

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The average score is 84%

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