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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Which of the following antibody types forms a pentamer?

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2)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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3)

Mode of IPV vaccine administration is:

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4)

The cytotoxic T-cells is involved in:

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5)

Tetanus toxoid is usually given to humans:

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6)

The antigen-antibody interactions occur in:

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7)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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8)

Small chemical groups on the antigen molecule that can react with antibody

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9)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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10)

What is the mode of administration for BCG vaccine?

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11)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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12)

The immunoglobulins participated in complement system formation are:

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13)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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14)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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15)

The effectiveness is:

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16)

The characteristic of antigen-antibody interactions occur in primary stage:

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17)

The class I MHC molecule appeared to bind with receptor of:

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18)

The classical pathway of complement activation is:

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19)

In an immune response the type of cell which gets activated earliest is:

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20)

All are mechanism of action of complement but except:

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21)

In order to elicit an immune response, a carbohydrate must be which of the following?

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22)

Vaccination is an example of?

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23)

The following statements are the use of passive immunization included but except one?

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24)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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25)

All are therapeutic applications of polyclonal antibodies but except one?

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26)

Antigen presenting cells for vaccine are:

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27)

In the application Antigen- Antibody reaction, which one is correct?

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28)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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29)

In the application Antigen- Antibody reaction, which one is correct?

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30)

What is the immune cell in adaptive immunity?

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31)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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32)

Which of the following statement is true regarding vaccination:

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33)

Which antibody is the first to be released into the blood following an infection?

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34)

Which of the following is not an ideal property of a vaccine?

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35)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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36)

The immune cells that is linked between innate and adaptive immunity are:

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37)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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38)

The immunoglobulins transport across epithelium:

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39)

The antibody-binding site is formed primarily by:

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40)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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41)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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42)

What is the mode of administration for PCV-13 vaccine?

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43)

The following statements are criteria for a good vaccine but which is incorrect statement?

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44)

The bonds involved in antigen-antibody interactions are

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45)

The technology used for the production of monoclonal antibodies is:

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46)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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47)

Which of the following is the site of T cell maturation?

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48)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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49)

All are examples of names of monoclonal antibodies but except one?

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50)

All are immune cells in innate immune system but except:

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51)

Primary lymphoid organs include

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52)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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53)

Infectious material from what illness was used to develop the first vaccine?

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54)

Graft and tumor rejection are mediated primarily by:

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55)

Which of the following is not the function of antibody?

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56)

The complement system involved in chemotaxis are:

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57)

The Adverse events following immunization (AEFI) are divided into:

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58)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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59)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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60)

What vaccine should not be frozen:

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61)

In the application Antigen- Antibody reaction, which one is not correct?

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62)

An antigen is:

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63)

The complement system consists of about:

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64)

The herd immunity is:

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65)

Immunogen is:

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66)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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67)

All are the measure for post rabies exposure prophylaxis, but except one?

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68)

The complement system involved in the inflammation are:

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69)

The first line of defense against invading pathogens:

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70)

What vaccine should be avoided for the pregnant woman?

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71)

The purpose of clinical trial of a vaccine is:

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72)

Injection of immunoglobulin is:

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73)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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74)

Which of the following statements are true regarding polio vaccines:

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75)

The immunoglobulins transport across placenta mostly:

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76)

The main advantage of passive immunization over active immunization is that:

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77)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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78)

The adverse effects of vaccines are linked to:

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79)

The characteristic of antigen-antibody interactions occur in second stage:

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80)

Which of the following antibodies have a positive effect on babies through breast feeding?

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81)

In the application Antigen- Antibody reaction, which one is correct?

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82)

What is the mode of administration for anti-measles vaccine?

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83)

The process of weakening a pathogen is called:

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84)

An epitope is:

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85)

Adjuvant used in HBV vaccine is:

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86)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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87)

The general principle of vaccination was established by:

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88)

All the given vaccines are attenuated or inactivated whole pathogen except:

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89)

Which of the following statement is true

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90)

All are functions of immunoglobulins but except:

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91)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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92)

Natural humoral immune response against a pathogen leads to the production of:

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93)

All are Antigen-Presenting Cells (APCs) but except:

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94)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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95)

The type of T-cells that destroy host cells bearing foreign antigen:

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96)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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97)

What is a live attenuated vaccine?

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98)

An immunoglobulin is a:

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99)

All are important characteristics of innate immunity but except:

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100)

Serum which contains antibodies is called:

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101)

The circulation of a two month old breast-fed baby will contain maternal:

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102)

The immune cells that is linked between innate and adaptive immunity are:

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103)

Adjuvant used in HPV vaccine is:

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104)

Successful immunization can be impaired by:

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105)

The impact is:

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106)

The naive T cells are:

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107)

Injection of anti-venom to a patient for snake bite is example of?

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108)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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109)

Several of the complement components are:

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110)

The Follicular Dendritic Cells (FDCs) is located in:

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111)

The role of the macrophage during an antibody response is to:

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112)

The efficacy is:

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113)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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114)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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115)

All the following comes under non-specific defence mechanism except

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116)

An epitope:

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117)

Which of the following is a polysaccharide vaccine:

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118)

The complement system are synthesized by:

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119)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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120)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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121)

The complement system involved in phagocytic function are:

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122)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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123)

The first recombinant antigen vaccine approved for human use is:

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124)

All are factors influencing in immunogenicity but except:

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125)

Newborns get their antibodies from mother’s milk. This is an example of?

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126)

What vaccine can be used for pregnant women?

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127)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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128)

The classical pathway of complement activation is:

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129)

All are 3 main effects of complement but except:

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130)

The class II MHC molecule appeared to bind with receptor of:

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