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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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2)

The class II MHC molecule appeared to bind with receptor of:

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3)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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4)

What is the mode of administration for BCG vaccine?

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5)

What is a live attenuated vaccine?

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6)

In the application Antigen- Antibody reaction, which one is not correct?

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7)

All are Antigen-Presenting Cells (APCs) but except:

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8)

The complement system are synthesized by:

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9)

Vaccination is an example of?

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10)

The immunoglobulins participated in complement system formation are:

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11)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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12)

The following statements are the use of passive immunization included but except one?

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13)

Which of the following statement is true

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14)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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15)

The characteristic of antigen-antibody interactions occur in second stage:

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16)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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17)

The circulation of a two month old breast-fed baby will contain maternal:

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18)

Natural humoral immune response against a pathogen leads to the production of:

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19)

Tetanus toxoid is usually given to humans:

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20)

Adjuvant used in HBV vaccine is:

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21)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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22)

The main advantage of passive immunization over active immunization is that:

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23)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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24)

In order to elicit an immune response, a carbohydrate must be which of the following?

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25)

The role of the macrophage during an antibody response is to:

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26)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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27)

An epitope is:

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28)

What is the mode of administration for anti-measles vaccine?

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29)

Which of the following antibodies have a positive effect on babies through breast feeding?

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30)

In an immune response the type of cell which gets activated earliest is:

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31)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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32)

The complement system involved in chemotaxis are:

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33)

What vaccine should be avoided for the pregnant woman?

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34)

All are therapeutic applications of polyclonal antibodies but except one?

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35)

The cytotoxic T-cells is involved in:

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36)

Which of the following is not the function of antibody?

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37)

All the following comes under non-specific defence mechanism except

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38)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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39)

Immunogen is:

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40)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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41)

Which of the following is not an ideal property of a vaccine?

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42)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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43)

What vaccine can be used for pregnant women?

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44)

What vaccine should not be frozen:

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45)

All are the measure for post rabies exposure prophylaxis, but except one?

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46)

Small chemical groups on the antigen molecule that can react with antibody

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47)

The naive T cells are:

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48)

The type of T-cells that destroy host cells bearing foreign antigen:

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49)

Which of the following statements are true regarding polio vaccines:

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50)

Several of the complement components are:

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51)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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52)

Which of the following statement is true regarding vaccination:

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53)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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54)

The antibody-binding site is formed primarily by:

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55)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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56)

Adjuvant used in HPV vaccine is:

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57)

All are functions of immunoglobulins but except:

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58)

Injection of immunoglobulin is:

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59)

The technology used for the production of monoclonal antibodies is:

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60)

Graft and tumor rejection are mediated primarily by:

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61)

An epitope:

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62)

An antigen is:

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63)

Which of the following is a polysaccharide vaccine:

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64)

The complement system consists of about:

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65)

Antigen presenting cells for vaccine are:

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66)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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67)

The class I MHC molecule appeared to bind with receptor of:

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68)

What is the mode of administration for PCV-13 vaccine?

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69)

The adverse effects of vaccines are linked to:

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70)

The effectiveness is:

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71)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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72)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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73)

Primary lymphoid organs include

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74)

The general principle of vaccination was established by:

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75)

The complement system involved in phagocytic function are:

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76)

The first line of defense against invading pathogens:

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77)

Infectious material from what illness was used to develop the first vaccine?

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78)

The immune cells that is linked between innate and adaptive immunity are:

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79)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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80)

The efficacy is:

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81)

What is the immune cell in adaptive immunity?

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82)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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83)

All are factors influencing in immunogenicity but except:

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84)

In the application Antigen- Antibody reaction, which one is correct?

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85)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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86)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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87)

The complement system involved in the inflammation are:

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88)

The first recombinant antigen vaccine approved for human use is:

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89)

All are mechanism of action of complement but except:

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90)

The classical pathway of complement activation is:

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91)

Serum which contains antibodies is called:

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92)

All are important characteristics of innate immunity but except:

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93)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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94)

Mode of IPV vaccine administration is:

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95)

An immunoglobulin is a:

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96)

In the application Antigen- Antibody reaction, which one is correct?

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97)

All are examples of names of monoclonal antibodies but except one?

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98)

All the given vaccines are attenuated or inactivated whole pathogen except:

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99)

The Adverse events following immunization (AEFI) are divided into:

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100)

All are immune cells in innate immune system but except:

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101)

Which of the following antibody types forms a pentamer?

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102)

The process of weakening a pathogen is called:

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103)

The impact is:

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104)

The immunoglobulins transport across placenta mostly:

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105)

The antigen-antibody interactions occur in:

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106)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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107)

The purpose of clinical trial of a vaccine is:

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108)

Which of the following is the site of T cell maturation?

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109)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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110)

Newborns get their antibodies from mother’s milk. This is an example of?

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111)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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112)

In the application Antigen- Antibody reaction, which one is correct?

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113)

The bonds involved in antigen-antibody interactions are

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114)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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115)

The following statements are criteria for a good vaccine but which is incorrect statement?

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116)

The classical pathway of complement activation is:

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117)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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118)

The Follicular Dendritic Cells (FDCs) is located in:

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119)

All are 3 main effects of complement but except:

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120)

The herd immunity is:

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121)

The immunoglobulins transport across epithelium:

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122)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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123)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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124)

Injection of anti-venom to a patient for snake bite is example of?

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125)

Which antibody is the first to be released into the blood following an infection?

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126)

The immune cells that is linked between innate and adaptive immunity are:

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127)

Successful immunization can be impaired by:

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128)

The characteristic of antigen-antibody interactions occur in primary stage:

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129)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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130)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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