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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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2)

Several of the complement components are:

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3)

Graft and tumor rejection are mediated primarily by:

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4)

In an immune response the type of cell which gets activated earliest is:

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5)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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6)

Natural humoral immune response against a pathogen leads to the production of:

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7)

Which of the following is not an ideal property of a vaccine?

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8)

Which of the following is not the function of antibody?

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9)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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10)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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11)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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12)

In the application Antigen- Antibody reaction, which one is correct?

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13)

What vaccine can be used for pregnant women?

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14)

All are examples of names of monoclonal antibodies but except one?

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15)

The classical pathway of complement activation is:

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16)

Vaccination is an example of?

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17)

Antigen presenting cells for vaccine are:

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18)

All are functions of immunoglobulins but except:

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19)

All are the measure for post rabies exposure prophylaxis, but except one?

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20)

The complement system consists of about:

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21)

Which of the following statement is true regarding vaccination:

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22)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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23)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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24)

The naive T cells are:

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25)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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26)

All are therapeutic applications of polyclonal antibodies but except one?

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27)

The efficacy is:

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28)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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29)

An immunoglobulin is a:

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30)

The complement system involved in the inflammation are:

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31)

In order to elicit an immune response, a carbohydrate must be which of the following?

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32)

The technology used for the production of monoclonal antibodies is:

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33)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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34)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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35)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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36)

An antigen is:

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37)

Which of the following statement is true

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38)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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39)

Injection of anti-venom to a patient for snake bite is example of?

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40)

The purpose of clinical trial of a vaccine is:

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41)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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42)

Infectious material from what illness was used to develop the first vaccine?

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43)

The Follicular Dendritic Cells (FDCs) is located in:

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44)

The type of T-cells that destroy host cells bearing foreign antigen:

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45)

The first recombinant antigen vaccine approved for human use is:

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46)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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47)

Mode of IPV vaccine administration is:

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48)

Successful immunization can be impaired by:

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49)

What vaccine should not be frozen:

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50)

What is the immune cell in adaptive immunity?

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51)

All the given vaccines are attenuated or inactivated whole pathogen except:

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52)

The circulation of a two month old breast-fed baby will contain maternal:

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53)

All are 3 main effects of complement but except:

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54)

An epitope is:

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55)

The antibody-binding site is formed primarily by:

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56)

What is the mode of administration for BCG vaccine?

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57)

All are Antigen-Presenting Cells (APCs) but except:

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58)

What is the mode of administration for anti-measles vaccine?

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59)

The immune cells that is linked between innate and adaptive immunity are:

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60)

The characteristic of antigen-antibody interactions occur in second stage:

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61)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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62)

The general principle of vaccination was established by:

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63)

The bonds involved in antigen-antibody interactions are

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64)

Immunogen is:

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65)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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66)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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67)

Adjuvant used in HPV vaccine is:

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68)

All are important characteristics of innate immunity but except:

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69)

In the application Antigen- Antibody reaction, which one is correct?

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70)

The immune cells that is linked between innate and adaptive immunity are:

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71)

The characteristic of antigen-antibody interactions occur in primary stage:

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72)

Which antibody is the first to be released into the blood following an infection?

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73)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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74)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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75)

Primary lymphoid organs include

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76)

The antigen-antibody interactions occur in:

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77)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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78)

Adjuvant used in HBV vaccine is:

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79)

The complement system involved in phagocytic function are:

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80)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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81)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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82)

The role of the macrophage during an antibody response is to:

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83)

What is the mode of administration for PCV-13 vaccine?

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84)

In the application Antigen- Antibody reaction, which one is not correct?

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85)

The Adverse events following immunization (AEFI) are divided into:

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86)

The immunoglobulins transport across placenta mostly:

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87)

The herd immunity is:

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88)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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89)

Injection of immunoglobulin is:

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90)

Serum which contains antibodies is called:

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91)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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92)

Small chemical groups on the antigen molecule that can react with antibody

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93)

The effectiveness is:

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94)

The immunoglobulins participated in complement system formation are:

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95)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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96)

The main advantage of passive immunization over active immunization is that:

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97)

Which of the following antibody types forms a pentamer?

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98)

Which of the following is the site of T cell maturation?

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99)

The cytotoxic T-cells is involved in:

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100)

The class I MHC molecule appeared to bind with receptor of:

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101)

In the application Antigen- Antibody reaction, which one is correct?

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102)

The following statements are criteria for a good vaccine but which is incorrect statement?

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103)

All are factors influencing in immunogenicity but except:

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104)

All are immune cells in innate immune system but except:

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105)

The following statements are the use of passive immunization included but except one?

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106)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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107)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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108)

What vaccine should be avoided for the pregnant woman?

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109)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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110)

Tetanus toxoid is usually given to humans:

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111)

The first line of defense against invading pathogens:

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112)

The adverse effects of vaccines are linked to:

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113)

An epitope:

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114)

The complement system are synthesized by:

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115)

The impact is:

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116)

Which of the following statements are true regarding polio vaccines:

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117)

The class II MHC molecule appeared to bind with receptor of:

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118)

The immunoglobulins transport across epithelium:

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119)

Which of the following antibodies have a positive effect on babies through breast feeding?

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120)

All are mechanism of action of complement but except:

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121)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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122)

What is a live attenuated vaccine?

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123)

Which of the following is a polysaccharide vaccine:

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124)

The process of weakening a pathogen is called:

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125)

All the following comes under non-specific defence mechanism except

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126)

Newborns get their antibodies from mother’s milk. This is an example of?

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127)

The complement system involved in chemotaxis are:

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128)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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129)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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130)

The classical pathway of complement activation is:

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