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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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2)

The class II MHC molecule appeared to bind with receptor of:

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3)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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4)

Mode of IPV vaccine administration is:

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5)

An epitope:

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6)

The Follicular Dendritic Cells (FDCs) is located in:

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7)

In the application Antigen- Antibody reaction, which one is correct?

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8)

The immunoglobulins transport across epithelium:

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9)

Which of the following is not an ideal property of a vaccine?

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10)

Adjuvant used in HBV vaccine is:

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11)

The circulation of a two month old breast-fed baby will contain maternal:

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12)

Which antibody is the first to be released into the blood following an infection?

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13)

All are examples of names of monoclonal antibodies but except one?

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14)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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15)

The following statements are the use of passive immunization included but except one?

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16)

Which of the following is not the function of antibody?

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17)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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18)

The class I MHC molecule appeared to bind with receptor of:

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19)

The adverse effects of vaccines are linked to:

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20)

In the application Antigen- Antibody reaction, which one is correct?

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21)

Small chemical groups on the antigen molecule that can react with antibody

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22)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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23)

Immunogen is:

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24)

The first line of defense against invading pathogens:

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25)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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26)

Which of the following antibodies have a positive effect on babies through breast feeding?

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27)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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28)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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29)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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30)

Which of the following statement is true

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31)

Serum which contains antibodies is called:

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32)

What is a live attenuated vaccine?

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33)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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34)

The characteristic of antigen-antibody interactions occur in primary stage:

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35)

Newborns get their antibodies from mother’s milk. This is an example of?

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36)

Injection of immunoglobulin is:

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37)

The impact is:

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38)

Adjuvant used in HPV vaccine is:

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39)

All are mechanism of action of complement but except:

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40)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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41)

What is the mode of administration for BCG vaccine?

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42)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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43)

What vaccine can be used for pregnant women?

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44)

Which of the following antibody types forms a pentamer?

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45)

The classical pathway of complement activation is:

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46)

What vaccine should be avoided for the pregnant woman?

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47)

The main advantage of passive immunization over active immunization is that:

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48)

An epitope is:

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49)

Which of the following is a polysaccharide vaccine:

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50)

The immune cells that is linked between innate and adaptive immunity are:

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51)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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52)

In order to elicit an immune response, a carbohydrate must be which of the following?

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53)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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54)

The type of T-cells that destroy host cells bearing foreign antigen:

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55)

The complement system involved in the inflammation are:

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56)

In the application Antigen- Antibody reaction, which one is not correct?

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57)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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58)

What is the immune cell in adaptive immunity?

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59)

The characteristic of antigen-antibody interactions occur in second stage:

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60)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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61)

Successful immunization can be impaired by:

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62)

Antigen presenting cells for vaccine are:

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63)

Tetanus toxoid is usually given to humans:

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64)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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65)

The process of weakening a pathogen is called:

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66)

The classical pathway of complement activation is:

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67)

The first recombinant antigen vaccine approved for human use is:

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68)

All are important characteristics of innate immunity but except:

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69)

The Adverse events following immunization (AEFI) are divided into:

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70)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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71)

An immunoglobulin is a:

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72)

What is the mode of administration for anti-measles vaccine?

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73)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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74)

Which of the following statement is true regarding vaccination:

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75)

Natural humoral immune response against a pathogen leads to the production of:

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76)

The herd immunity is:

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77)

Which of the following statements are true regarding polio vaccines:

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78)

The effectiveness is:

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79)

Graft and tumor rejection are mediated primarily by:

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80)

The cytotoxic T-cells is involved in:

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81)

The following statements are criteria for a good vaccine but which is incorrect statement?

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82)

The efficacy is:

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83)

The bonds involved in antigen-antibody interactions are

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84)

All the following comes under non-specific defence mechanism except

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85)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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86)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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87)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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88)

The antigen-antibody interactions occur in:

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89)

All are the measure for post rabies exposure prophylaxis, but except one?

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90)

Vaccination is an example of?

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91)

The general principle of vaccination was established by:

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92)

All are factors influencing in immunogenicity but except:

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93)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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94)

In the application Antigen- Antibody reaction, which one is correct?

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95)

Primary lymphoid organs include

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96)

All are Antigen-Presenting Cells (APCs) but except:

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97)

The complement system are synthesized by:

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98)

The technology used for the production of monoclonal antibodies is:

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99)

The immunoglobulins transport across placenta mostly:

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100)

All are functions of immunoglobulins but except:

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101)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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102)

The antibody-binding site is formed primarily by:

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103)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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104)

The complement system involved in phagocytic function are:

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105)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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106)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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107)

Injection of anti-venom to a patient for snake bite is example of?

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108)

The purpose of clinical trial of a vaccine is:

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109)

What vaccine should not be frozen:

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110)

What is the mode of administration for PCV-13 vaccine?

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111)

Several of the complement components are:

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112)

The role of the macrophage during an antibody response is to:

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113)

In an immune response the type of cell which gets activated earliest is:

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114)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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115)

The immunoglobulins participated in complement system formation are:

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116)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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117)

All are 3 main effects of complement but except:

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118)

An antigen is:

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119)

The naive T cells are:

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120)

The immune cells that is linked between innate and adaptive immunity are:

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121)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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122)

All are therapeutic applications of polyclonal antibodies but except one?

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123)

Which of the following is the site of T cell maturation?

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124)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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125)

The complement system consists of about:

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126)

All the given vaccines are attenuated or inactivated whole pathogen except:

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127)

Infectious material from what illness was used to develop the first vaccine?

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128)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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129)

The complement system involved in chemotaxis are:

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130)

All are immune cells in innate immune system but except:

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