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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Preparation (Dr. Khor Hok Sunn)

 

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1)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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2)

The first recombinant antigen vaccine approved for human use is:

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3)

In the application Antigen- Antibody reaction, which one is correct?

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4)

The technology used for the production of monoclonal antibodies is:

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5)

The main advantage of passive immunization over active immunization is that:

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6)

Vaccination is an example of?

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7)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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8)

The bonds involved in antigen-antibody interactions are

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9)

The naive T cells are:

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10)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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11)

Newborns get their antibodies from mother’s milk. This is an example of?

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12)

Which of the following is not an ideal property of a vaccine?

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13)

Which of the following antibody types forms a pentamer?

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14)

Graft and tumor rejection are mediated primarily by:

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15)

The purpose of clinical trial of a vaccine is:

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16)

Primary lymphoid organs include

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17)

Which of the following is the site of T cell maturation?

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18)

What is the mode of administration for PCV-13 vaccine?

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19)

An immunoglobulin is a:

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20)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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21)

The complement system involved in chemotaxis are:

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22)

The immune cells that is linked between innate and adaptive immunity are:

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23)

Injection of immunoglobulin is:

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24)

The complement system involved in phagocytic function are:

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25)

Mode of IPV vaccine administration is:

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26)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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27)

What vaccine should be avoided for the pregnant woman?

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28)

The complement system are synthesized by:

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29)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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30)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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31)

The Follicular Dendritic Cells (FDCs) is located in:

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32)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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33)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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34)

The general principle of vaccination was established by:

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35)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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36)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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37)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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38)

Which of the following is a polysaccharide vaccine:

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39)

Immunogen is:

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40)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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41)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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42)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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43)

All are examples of names of monoclonal antibodies but except one?

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44)

All are Antigen-Presenting Cells (APCs) but except:

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45)

Successful immunization can be impaired by:

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46)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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47)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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48)

The classical pathway of complement activation is:

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49)

The immunoglobulins transport across placenta mostly:

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50)

The Adverse events following immunization (AEFI) are divided into:

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51)

Which antibody is the first to be released into the blood following an infection?

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52)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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53)

All are important characteristics of innate immunity but except:

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54)

In the application Antigen- Antibody reaction, which one is correct?

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55)

The immunoglobulins transport across epithelium:

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56)

Which of the following statement is true regarding vaccination:

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57)

All the following comes under non-specific defence mechanism except

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58)

The efficacy is:

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59)

An antigen is:

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60)

The class II MHC molecule appeared to bind with receptor of:

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61)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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62)

In an immune response the type of cell which gets activated earliest is:

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63)

What is the mode of administration for BCG vaccine?

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64)

The antibody-binding site is formed primarily by:

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65)

The first line of defense against invading pathogens:

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66)

All the given vaccines are attenuated or inactivated whole pathogen except:

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67)

The following statements are criteria for a good vaccine but which is incorrect statement?

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68)

The herd immunity is:

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69)

Tetanus toxoid is usually given to humans:

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70)

The adverse effects of vaccines are linked to:

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71)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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72)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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73)

In order to elicit an immune response, a carbohydrate must be which of the following?

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74)

All are therapeutic applications of polyclonal antibodies but except one?

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75)

What is the immune cell in adaptive immunity?

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76)

The circulation of a two month old breast-fed baby will contain maternal:

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77)

Natural humoral immune response against a pathogen leads to the production of:

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78)

The process of weakening a pathogen is called:

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79)

What vaccine should not be frozen:

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80)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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81)

Adjuvant used in HPV vaccine is:

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82)

All are 3 main effects of complement but except:

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83)

The classical pathway of complement activation is:

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84)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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85)

The complement system consists of about:

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86)

All are factors influencing in immunogenicity but except:

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87)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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88)

The complement system involved in the inflammation are:

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89)

The effectiveness is:

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90)

The antigen-antibody interactions occur in:

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91)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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92)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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93)

Adjuvant used in HBV vaccine is:

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94)

An epitope:

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95)

Several of the complement components are:

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96)

Which of the following is not the function of antibody?

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97)

What is a live attenuated vaccine?

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98)

What vaccine can be used for pregnant women?

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99)

All are the measure for post rabies exposure prophylaxis, but except one?

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100)

Serum which contains antibodies is called:

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101)

All are mechanism of action of complement but except:

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102)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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103)

The characteristic of antigen-antibody interactions occur in primary stage:

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104)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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105)

The class I MHC molecule appeared to bind with receptor of:

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106)

All are immune cells in innate immune system but except:

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107)

Which of the following antibodies have a positive effect on babies through breast feeding?

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108)

The characteristic of antigen-antibody interactions occur in second stage:

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109)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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110)

Which of the following statement is true

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111)

Which of the following statements are true regarding polio vaccines:

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112)

The type of T-cells that destroy host cells bearing foreign antigen:

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113)

Injection of anti-venom to a patient for snake bite is example of?

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114)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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115)

Infectious material from what illness was used to develop the first vaccine?

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116)

The cytotoxic T-cells is involved in:

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117)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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118)

An epitope is:

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119)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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120)

The following statements are the use of passive immunization included but except one?

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121)

The immunoglobulins participated in complement system formation are:

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122)

The immune cells that is linked between innate and adaptive immunity are:

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123)

The impact is:

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124)

In the application Antigen- Antibody reaction, which one is not correct?

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125)

The role of the macrophage during an antibody response is to:

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126)

What is the mode of administration for anti-measles vaccine?

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127)

All are functions of immunoglobulins but except:

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128)

Antigen presenting cells for vaccine are:

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129)

In the application Antigen- Antibody reaction, which one is correct?

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130)

Small chemical groups on the antigen molecule that can react with antibody

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