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Immunologie Générale Et Appliquée Preparation (Dr. Khor Hok Sunn)

 

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1)

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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2)

Which of the following is not an ideal property of a vaccine?

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3)

Which of the following is a polysaccharide vaccine:

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4)

The complement system involved in the inflammation are:

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5)

The technology used for the production of monoclonal antibodies is:

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6)

Vaccination is an example of?

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7)

What is the mode of administration for PCV-13 vaccine?

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8)

Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?

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9)

In the application Antigen- Antibody reaction, which one is not correct?

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10)

Infectious material from what illness was used to develop the first vaccine?

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11)

In the application Antigen- Antibody reaction, which one is correct?

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12)

Which of the following immune cells/ molecules are most effective at destroying intracellular pathogens?

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13)

The immunoglobulins transport across epithelium:

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14)

Skin is the largest organ in the body and protects us by preventing pathogen entry. This is an example of?

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15)

The role of the macrophage during an antibody response is to:

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16)

Adjuvant used in HBV vaccine is:

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17)

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

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18)

The immunoglobulins participated in complement system formation are:

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19)

The characteristic of antigen-antibody interactions occur in tertiary stage:

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20)

The first recombinant antigen vaccine approved for human use is:

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21)

The complement system are synthesized by:

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22)

The cytotoxic T-cells is involved in:

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23)

The impact is:

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24)

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?

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25)

Successful immunization can be impaired by:

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26)

All are the measure for post rabies exposure prophylaxis, but except one?

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27)

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

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28)

All the following comes under non-specific defence mechanism except

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29)

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

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30)

An antigen is:

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31)

In the application Antigen- Antibody reaction, which one is correct?

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32)

All are immune cells in innate immune system but except:

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33)

The immune cells that is linked between innate and adaptive immunity are:

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34)

Graft and tumor rejection are mediated primarily by:

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35)

The classical pathway of complement activation is:

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36)

The immunoglobulins transport across placenta mostly:

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37)

The naive T cells are:

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38)

An epitope:

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39)

The inability of very young children to respond to the measles vaccine due to the persistence of maternal antibody is similar in principle to and exploited in which of the following?

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40)

The adverse effects of vaccines are linked to:

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41)

Which of the following is not the function of antibody?

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42)

Immunogen is:

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43)

What vaccine should be avoided for the pregnant woman?

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44)

The class I MHC molecule appeared to bind with receptor of:

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45)

What is the immune cell in adaptive immunity?

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46)

What is the mode of administration for BCG vaccine?

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47)

Injection of anti-venom to a patient for snake bite is example of?

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48)

Often patients are immune to diseases like chicken pox once infecte. This immunity is an example of?

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49)

Small chemical groups on the antigen molecule that can react with antibody

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50)

Antigen presenting cells for vaccine are:

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51)

To drive antigen for proliferating and differentiating into armed effector T cells, The activated T cells produce :

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52)

Adjuvant used in HPV vaccine is:

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53)

All are examples of names of monoclonal antibodies but except one?

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54)

The type of T-cells that destroy host cells bearing foreign antigen:

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55)

The complement system consists of about:

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56)

In the immune response to a hapten–protein conjugate, in order to get anti-hapten antibodies, it is essential that:

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57)

The first line of defense against invading pathogens:

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58)

The antigen-antibody interactions occur in:

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59)

The following statements are related to hepatitis B and pregnancy which statement is incorrect?

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60)

Which of the following antibodies would most likely be found in body secretions such as tears, milk, saliva and mucus?

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61)

Tetanus toxoid is usually given to humans:

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62)

The immune cells that is linked between innate and adaptive immunity are:

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63)

Primary lymphoid organs include

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64)

Which of the following statement is true

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65)

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

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66)

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

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67)

For vaccination against mycobacterial diseases such as tuberculosis, the most important facet of the immune response to be stimulated is:

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68)

The class II MHC molecule appeared to bind with receptor of:

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69)

The Follicular Dendritic Cells (FDCs) is located in:

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70)

The class of immunoglobulin present in highest concentration in blood of a human newborn is

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71)

To which one of the following groups would it be acceptable to give a live attenuated viral vaccine?

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72)

In the vaccine response, interleukin (IL-4, IL-5, IL-13) acts to?

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73)

The class of immunoglobulin present in highest concentration in blood of a human newborn is:

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74)

Which of the following statement is true regarding vaccination:

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75)

An epitope is:

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76)

The classical pathway of complement activation is:

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77)

What is a live attenuated vaccine?

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78)

Several of the complement components are:

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79)

The complement system involved in phagocytic function are:

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80)

All are factors influencing in immunogenicity but except:

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81)

All are 3 main effects of complement but except:

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82)

The herd immunity is:

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83)

Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces?

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84)

Newborns get their antibodies from mother’s milk. This is an example of?

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85)

Serum which contains antibodies is called:

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86)

Mode of IPV vaccine administration is:

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87)

An immunoglobulin is a:

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88)

The effectiveness is:

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89)

Which of the following statements are true regarding polio vaccines:

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90)

All are mechanism of action of complement but except:

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91)

All are functions of immunoglobulins but except:

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92)

All are Antigen-Presenting Cells (APCs) but except:

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93)

The antibody-binding site is formed primarily by:

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94)

The Adverse events following immunization (AEFI) are divided into:

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95)

The circulation of a two month old breast-fed baby will contain maternal:

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96)

A vaccine that activates both cell- mediated and humoral immunity would most likely be :

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97)

The following statements are the use of passive immunization included but except one?

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98)

Which of the following antibody types forms a pentamer?

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99)

The efficacy is:

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100)

All the given vaccines are attenuated or inactivated whole pathogen except:

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101)

Which antibody is the first to be released into the blood following an infection?

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102)

Which of the following immune mechanism is responsible for protecting us from diseases of other species?

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103)

The following statements are criteria for a good vaccine but which is incorrect statement?

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104)

Which of the following is the site of T cell maturation?

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105)

Hemolytic disease of the newborn caused by Rh blood group incompatibility requires maternal antibody to enter the fetal bloodstream. Therefore, the mediator of this disease is:

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106)

In an immune response the type of cell which gets activated earliest is:

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107)

The bonds involved in antigen-antibody interactions are

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108)

What vaccine should not be frozen:

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109)

Name the cytokine produced by Th1 cells that are responsible for activating macrophages:

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110)

All are important characteristics of innate immunity but except:

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111)

Injection of immunoglobulin is:

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112)

What is the mode of administration for anti-measles vaccine?

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113)

The purpose of clinical trial of a vaccine is:

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114)

Which of the following antibodies have a positive effect on babies through breast feeding?

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115)

In the application Antigen- Antibody reaction, which one is correct?

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116)

The characteristic of antigen-antibody interactions occur in second stage:

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117)

The general principle of vaccination was established by:

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118)

Natural humoral immune response against a pathogen leads to the production of:

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119)

The complement system involved in chemotaxis are:

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120)

HBV vaccine and HBIG are given at same time at two different injection sites within:

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121)

The following statements are related to Rhesus D alloimmunization in pregnancy which statement is incorrect?

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122)

The characteristic of antigen-antibody interactions occur in primary stage:

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123)

The process of weakening a pathogen is called:

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124)

All are therapeutic applications of polyclonal antibodies but except one?

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125)

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

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126)

During the maturation of a B lymphocyte, the first immunoglobulin heavy chain synthesized is:

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127)

What vaccine can be used for pregnant women?

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128)

A primary immune response in an adult human requires approximately how much time to produce detectable antibody levels in the blood?

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129)

In order to elicit an immune response, a carbohydrate must be which of the following?

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130)

The main advantage of passive immunization over active immunization is that:

Your score is

The average score is 84%

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