Immunologie GΓ©nΓ©rale Et AppliquΓ©e Test

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Immunologie GΓ©nΓ©rale Et AppliquΓ©e Test

 

1 / 60

Cytokines attract which of the following to the affected tissue?

2 / 60

A 52-year-old man who receives radiation therapy and cytotoxic drugs for treatment of cancer sustains significant damage to his bone marrow. Which of the following changes will most likely occur?

3 / 60

Which of the following is not a function of the innate immune system?

4 / 60

The germinal center reaction generates long lived plasma cells which secrete protective high affinity B cells for many years. Where do these cells reside?

5 / 60

Precursors of macrophages are called?

6 / 60

At the peak of a CD8+ T cell response to a new microbe, what is the fold increase in the number of microbe-specific T cells in an individual compared to the number of naïve CD8+ T cells specific for the microbe before infection?

7 / 60

Langerhans’ cells are found in?

8 / 60

In both B and T cell development, there is stage when a pre-antigen receptor (pre B cell receptor or pre T cell receptor) is expressed. Which of the following accurately describes an important function of these pre-antigen receptors?

9 / 60

A drug that blocks the function of the chemokine receptor CCR7 would result in which of the following abnormalities?

10 / 60

Which of the following statements regarding the functional properties of cytokines is false?

11 / 60

A vaccine administered in the autumn of one year may protect against the prevalent strain of influenza virus that originated in Hong Kong that same year, but it will not protect against another strain of influenza virus that originated in Russia. This phenomenon illustrates which property of the adaptive immune system?

12 / 60

Which of the following mechanisms contributes most to both Ig and TCR diversity?

13 / 60

When a B-lymphocyte encounters a foreign antigen with the appropriate specificity?

14 / 60

When antigens enter through the skin, in what organs are they concentrated?

15 / 60

Bactérie extracellulaire αžαŸ’αžšαžΌαžœαž”αžΆαž“ lysé αž™αŸ‰αžΆαž„αž”αŸ’αžšαžŸαžΎαžšαžŠαŸ„αž™αžŸαžΆαžš

16 / 60

Toxines αžαŸ’αžšαžΌαžœαž”αžΆαž“ neutralisé αžŠαŸ„αž™

17 / 60

Défensine αž‡αžΆ:

18 / 60

Cytokine αž…αŸ†αž”αž„ αžŠαŸ‚αž›αž•αž›αž·αžαžŠαŸ„αž™ lymphocyte Th1 αž‚αžΊ:

19 / 60

Cytokine αž…αŸ†αž”αž„ αžŠαŸ‚αž›αž•αž›αž·αžαžŠαŸ„αž™ lymphocyte Th2 αž‚αžΊ:

20 / 60

Immunoglobuline αž“αŸ…αž›αžΎαž•αŸ’αž‘αŸƒαžšαž”αžŸαŸ‹ lymphocyte B αž˜αžΆαž“αžαž½αž“αžΆαž‘αžΈ:

21 / 60

αž“αŸ…αž€αŸ’αž“αž»αž„αž€αžΆαžšαž†αŸ’αž›αžΎαž™αžαž”αžšαž”αžŸαŸ‹αž”αŸ’αžšαž–αŸαž“αŸ’αž’αž—αžΆαž–αžŸαž»αŸ†αžΆαž‘αŸ…αž“αžΉαž„αž’αž„αŸ‹αž‘αžΈαž αŸ’αžŸαŸ‚αž“ αž˜αž½αž™αŸˆ

22 / 60

αž˜αž»αžαž„αžΆαžš effecteur αžšαž”αžŸαŸ‹αž’αž„αŸ’αž‚αž”αžŠαž·αž”αž€αŸ’αž αž€αŸ’αž“αž»αž„αž€αžΆαžšαž”αŸ†αž•αŸ’αž›αžΆαž‰αž€αŸ„αžŸαž·αž€αžΆ cible αž”αŸ’αžšαž–αŸ’αžšαž·αžαŸ’αžαž‘αžΎαž„αžαžΆαž˜αžšαž™αŸˆ

23 / 60

αžαžΎαž˜αŸ‰αžΌαž›αŸαž‚αž»αž›αžŽαžΆαž˜αž½αž™αž‡αžΆαž˜αŸ‰αžΌαž›αŸαž‚αž»αž›αžšαž”αžŸαŸ‹ HLA classe II:

24 / 60

αžœαŸ‰αžΆαž€αŸ‹αžŸαžΆαŸ†αž„ αž€αžΆαžšαž–αžΆαžšαžšαž”αŸαž„αž‡αžΆ αžœαŸ‰αžΆαž€αŸ‹αžŸαžΆαŸ†αž„αžŠαŸ‚αž› αž—αŸ’αž‰αŸ„αž…αž‡αžΆαžŸαŸ†αžαžΆαž“αŸ‹

25 / 60

Which of the following is a polysaccharide vaccine:

26 / 60

The classical pathway of complement activation is:

27 / 60

Several of the complement components are:

28 / 60

The impact is:

29 / 60

The following statements are important mechanisms in which immunoglobulin molecules are essential included but except one?

30 / 60

The class I MHC molecule appeared to bind with receptor of:

31 / 60

An epitope:

32 / 60

Which category of hypersensitivity best describes hemolytic disease of the newborn caused by Rh incompatibility?

33 / 60

A patient presents with an increased number of lymphocytes in his peripheral blood. Which of the following is an appropriate technique to find out which type of lymphocytes these are?

34 / 60

The characteristic of antigen-antibody interactions occur in primary stage:

35 / 60

Adjuvant used in HPV vaccine is:

36 / 60

A potential disadvantage of immunological protection using passive transfer of horse globulins is:

37 / 60

In the vaccine response, INF gamma, TNF alpha and IL12 act on?

38 / 60

All are functions of immunoglobulins but except:

39 / 60

The herd immunity is:

40 / 60

Which of the following antibody types forms a pentamer?

41 / 60

In the application Antigen- Antibody reaction, which one is correct?

42 / 60

An antigen is:

43 / 60

The following statements are the use of passive immunization included but except one?

44 / 60

The efficacy is:

45 / 60

Newborns get their antibodies from mother’s milk. This is an example of?

46 / 60

The adverse effects of vaccines are linked to:

47 / 60

All are factors influencing in immunogenicity but except:

48 / 60

An immunoglobulin is a:

49 / 60

The technology used for the production of monoclonal antibodies is:

50 / 60

The first recombinant antigen vaccine approved for human use is:

51 / 60

The naive T cells are:

52 / 60

The type of T-cells that destroy host cells bearing foreign antigen:

53 / 60

The immunoglobulins transport across epithelium:

54 / 60

In order to elicit an immune response, a carbohydrate must be which of the following?

55 / 60

All the given vaccines are attenuated or inactivated whole pathogen except:

56 / 60

The bonds involved in antigen-antibody interactions are

57 / 60

The immunoglobulins transport across placenta mostly:

58 / 60

What is the minimum percentage of children which needs to be vaccinated successfully in order to achieve herd immunity to diphtheria:

59 / 60

What is a live attenuated vaccine?

60 / 60

The ideal storage conditions of adjuvanted vaccines in a refrigerator are between:

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