Immunology Preparation (Pr. Kiet Vannseth)

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1) The following statement are MOST closely related to each, EXCEPT:

a. Antibody

b. Antigen

c. Allergen

d. Epitope

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2) The Complement that gives Anaphylotoxin much potent is:

a. C2b

b. C4a

c. C5a

d. C3a

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3) T cells secreted cytokine to activate cells in blood vessel, This phenomen is called:

a. Endocrine

b. Paracrine

c. Autocine

d. All answers

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4) The most infection chronic and acute HBV is in?:

a. Female

b. Male

c. Children

d. Adult

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5) The following viral hepatitis are chronic hepatitis, EXCEPT?:

a. Hepatitis A

b. Hepatitis B

c. Heepatitis C

d. Hepatitis D

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6) The two types of lymphocytes are ?:

a. Platelet and Erythrocyte

b. Platelet and B cells

c. Erythrocyte and T cells

d. T and B cells

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7) The following answer is the best marker for Tc cells?:

a. CD4

b. CD21

c. CD3

d. CD8

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8) Identity the phagocytic cells that have Toll like Receptor on their membrane:

a. Neutrophil

b. Basophil

c. Macrophage

d. Eosinophil

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9) Variable regions of immunoglobulin are:

a. Specific recognition of antigen

b. Able to fix complement

c. N-terminal of heavy chains

d. C-terminal of heavy chains

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10) Which cell is T helper:

a. CD4

b. CD15

c. CD14

d. CD8

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11) The Live Attenuated Vaccines are used for the diseases below?:

a. All answers

b. Hepatitis A

c. Varicella zoster

d. Measles

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12) Which of the following immune cells are effective to destroying intracellular pathogens:

a. T helper cells

b. B cells

c. T cytolytic cells

d. Antibodies

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13) Which of the following bacteriocidal mechanisms is oxygen dependant?:

a. NADPH oxidation

b. Lactoferrin

c. Hydrolytic enzymes

d. Defensins

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14)

T-cell receptors or antibodies react with antigens:

a. Because they have specific receptors for antigen

b. Because both 'have light chain and heavy chain polypeptides

c. Because both are made by lymphocytes

d. Cause histamine release

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15) Which of the following immune cells/molecules are most effective to destroying intracellular
pthogens ?:

a. B cells

b. T helper cells

c. T cytotoxic cells

d. Plasma cells

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16) Which organ does hepatitis affect?:

a. Brain

b. Heart

c. Kidneys

d. Liver

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17)

The following statements are true for Antibodies

a. Contain cytoplasmic region

b. Are made from alpha and beta chains

c. Are carbohydrates

d. Have variable region

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18)

Which cells are proliferated from myeloid progenitor:

a. TH1

b. Dendritic cells

c. Lymphocytes

d. B cells

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19) Where is the variable region of Immunoglobulin?:

a. CL

b. VL

c. CH2

d. CH3

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20) The primairy response of antibody to the HBV is?:

a. IgM

b. IgE

c. IgA

d. IgG

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21) The following statement is true for helper T-cells :

a. Helper cells recognize antigen with MHC class II

b. Helper cells recognize antigen with MHC class I

c. Helper cells recognize antigen with MHC class I and II

d. Cytotoxic cells recognize antigen with MHC class II

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22) The following activities are belong to the B-cells :

a. Act as antigen-processing cells

b. Receptor antigen monovalent

c. Antibodies response to antigens

d. Differentiate into plasma cells

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23)

Which immunoglobulin is the principal one that is unkown function:

a. IgM

b. IgA

c. IgG

d. IgD

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24)

The followings statement are TRUE for Target cell lysis and destruction,EXCEPT :

a. Complement binding to IgG and IgM which have bound to epitopes on the target cell

b. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

c. Complement binding to IgE antibodies which have bound to epitopes on the cell surface

d. Perforin released from antigen-specific cytotoxic T-cells

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25)

The component of immune system that can cause inflammation is :

a. Macrophage

b. Immunoglobulin

c. Complement

d. T lymphocytes

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26) B cells that produce large amounts of antibody are called?:

a. Memory B cells

b. Neutrophils

c. Plasma cells

d. T cells

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27) The percentage of TH cell among lymphocytes is?:

a. 7%

b. 19%

c. 46%

d. 23%

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28)

All of the following are true with respect to IgG antibodies, EXCEPT:

a. They mediate allergic reaction

b. They are glycoproteins

c. They fix complement

d. They occur on the surface of B lymphocytes

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29)

The major histocompatibility complex proteins function to:

a. Bind antigen for presentation to T-cells

b. Degrade T4 and T8 polypeptides

c. Bind complement for cell lysis

d. Bind antibody for lymphokine production

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30) The following viral hepatitis is enteric hepatitis?:

a. Hepatitis A

b. Hepatitis D

c. Heepatitis C

d. Hepatitis B

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31) The following answers are true for phagocytosis, EXCEPT:

a. Ingest pathogen

b. Supported by complement

c. NK cell

d. Opsonisation

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32) The following vaccines are Live Attenuated Vaccines, EXCEPT?:

a. Tetanus

b. Varicella

c. Hepatitis A

d. Polio

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33)

Immediate hypersensitivity reactions are below, EXCEPT:

a. If the antigen is an allergen

b. Result from histamine release

c. Phagocytosis

d. The consequence of antigen-antibody reactions

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34)

What distinguishes helper T-cells from cytotoxic T-cells:

a. Tc recognize antigen with MHC I

b. Tc recognize antigen with MHC I and Th recognize antigen with MHC II

c. Th recognize antigen with MHC I

d. Th recognize antigen with MHC II

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35) These cells can be infected by Mycobacterium tuberculosis:

a. Neutrophil

b. Lymphocyte

c. Macrophage

d. Eosinophil

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36)

The following statements are true for Immunoglobins, EXCEPT:

a. Are antibodies

b. Possess both variable and constant regions

c. All have receptors for complement

d. Five major classes IgM, IgG, IgA, IgD, IgE

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37) The Natural Killer Cells work in the immune system :

a. Innate immunity

b. Adaptive immunity

c. Kill extracellular antigen

d. Adaptive immunity and Innate immunity

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38) The much potent anaphylotoxin of the complement is:

a. C2b

b. C4a

c. C3a

d. C5a

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39)

Which of the following causes AIDS ?:

a. Bacteria

b. Retrovirus

c. TMV

d. Fungus

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40)

The following statements are not true for Immunoglobins

a. Five major classes of immunoglobulin

b. They have Fab

c. Possess both variable and constant regions

d. All have receptors for complement

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41)

Which of the following represent immune system dysfunctions:

a. Severe immunodeficiency

b. T cells proliferation

c. Facilitated by antibodies

d. Mast cells release histamine

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42) The lectin pathway of the complement is initiated by:

a. C3

b. C1qrs

c. MBL

d. Factor B

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43) The chronic HCV infection develop hepatocellular carcinoma in the rate of?:

a. 10%

b. 20%

c. 5%

d. 50%

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44)

One principal function of complement is not true:

a. Activate perforins

b. Phagocytize antigens

c. Mediate the release of histamine

d. Lyse target cells

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45) The pathway of the complement that can lyse bacteria is:

a. Lytic pathway

b. Classical pathway

c. Alternative pathway

d. Lectin pathway

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46) These blood cells have memory after pathogens infection, EXCEPT? TH cells?:

a. Macrophages

b. Tc cells

c. B cells

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47) An antigenic determinant is:

a. Recognized by a epitope

b. Molecule of antigen

c. Recognized by macrophage

d. A fragment of Antigen

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48) Myeloid cells below lived in tissue:

a. Basophil

b. Neutrophil

c. Lymphocyte

d. Macrophage

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49) Pepsin cleaves what region of immunoglobulin?:

a. Heavy chain and Light chain

b. Hinge region

c. Light chain

d. Heavy chain

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50) Biological effect of Complement C2b is:

a. Anaphylaxis

b. Edema

c. Opsonisation

d. Phagocytosis

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51) The class of an immunoglobulin is determined by:

a. The light chain

b. The heavy chain

c. The antigen

d. Class I and II MHC

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52) Which type of antibody is not effective in activating complement?:

a. IgG1

b. IgG3

c. IgG4

d. IgG2

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53) Which of the following antibody fragments consists of a dimer of the heavy-chain constant
region but lacks the CH1 domains?:

a. Fc

b. Fab

c. F(ab)’2

d. F(ab)

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54) Which immunoglobulin is used to test for blood group:

a. IgA

b. IgG

c. IgM

d. IgE

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55)

The disease below can cause allergic reaction:

a. Cancer

b. Hepatitis

c. Thalassemia

d. Asthma

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56) The region of immunoglobulin term: Binds to various cellular receptors and to complement:

a. Light chain

b. Heavy chain

c. Fab region

d. Fc region

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57) Which of the following DOES NOT play a role in antigen presentation:

a. MHC class III molecules

b. Complement

c. MHC class I molecules

d. MHC class II molecules

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58) HBV infection is characterized by the present of ?:

a. All answers

b. HBcAg

c. HBeAg

d. HBsAg

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59) The answers below are characteristic of antigen, EXCEPT:

a. Contain epitopes

b. Contain paratopes

c. Are toxin

d. React with antibody

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60) The Immunoglobulins are secreted by:

a. T-cells

b. Macrophages

c. B-cells

d. Plasma cells

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61)

Which of the following immunoglobulins is present normally in plasma at the highest concentration?:

a. IgE

b. IgM

c. IgG

d. IgA

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62) All of the following are a part of innate immune respond, EXCEPT :

a. Natural Killer cells

b. Macrophage secrete cytokines

c. T cells secrete antibody

d. Pathways of complement activation

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63) The family of hepatitis C virus is?:

a. Hepanavirus

b. Rotavirus

c. Ribovirus

d. Flavivirus

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64) The following hepatitis can be prevented by vaccination :

a. Hepatitis B and C

b. Hepatitis A and B

c. Hepatitis D and C

d. Hepatitis C and E

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65) All of the following are the type RNA virus, EXCEPT?:

a. Hepatitis B

b. Hepatitis C

c. Hepatitis E

d. Hepatitis A

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66) Which cell is Monocyte:

a. CD14

b. CD8

c. CD4

d. CD15

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67) The following answers are true for IgM antibodies, EXCEPT:

a. Fix complement

b. Anti infectious

c. Cause of allergy

d. Pentametric form

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68) These organ is primary lymphoid organ of human?:

a. Lymph node

b. Thymus

c. Spleen

d. Tonsil

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69)

The following statement are for adaptive immune response, EXCEPT :

a. Is mediated by the humoral and cellular of the immune

b. Can be facilitated by antibodies

c. Can be facilitated through T-cells

d. Can be facilitated through macrophage cells

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70) The following answer is specific for antigen:

a. Hinge region

b. Fab region

c. Heavy chain

d. Fc region

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71)

The T3 complex of the T-cell receptor :

a. Mediates Immunoglobulin class switching

b. Causes the histamine

c. To transduce a signal to the cell's interior binding to antigen

d. Binds complement

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72)

Which of the following immunoglobulin can across placenta with the highest concentration?:

a. IgG2

b. IgG1

c. IgG3

d. IgG4

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73)

The function of MHC class II is:

a. Recognized by the CD8

b. Unable to carry antigen fragment

c. Participated in the presentation of Ag

d. Recognized by CD4

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74) The Complement that produce anaphylactic much more potent is:

a. C5a

b. C2b

c. C4a

d. C3a

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75) Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:

a. Hepatitis B virus

b. Polio

c. Haemophilus influenzae B

d. Neisseria meningitides

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76) The following disease is the cancer of lymphocyte?:

a. Mycobacterium

b. Listeria

c. Lymphocytopenia

d. Non-Hodgkin lymphoma

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77)

The following statements are true for Antibodies, EXCEPT:

a. Non immunogen

b. Made of heavy and light chains

c. Composed of variable and constant regions

d. They have hypervariable region

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78) The first sign of infection is the characteristic appearance of ?:

a. HBeAg

b. HBsAb

c. HBsAg

d. HBcAb

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79)

Which among the following is anti-bacterial ?:

a. Protein

b. Lysozyme

c. Interferon

d. Hormone

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80) The function of major histocompatibility complex for antigen in the cytosol is:

a. Presentation antigen to Tc-cells

b. Bind complement for cell lysis

c. Presentation antigen to Th-cells

d. Transport protein

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81) The following immunoglobulin(s) become monomer when they attaché antigen :

a. IgM

b. IgE

c. IgG

d. IgA

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82) Which of the following components of the adaptive immune system secretes immunoglobulin
(Ig)?:

a. Activated B cell (plasma cell)

b. CD8+ cytotoxic T cell (CTL)

c. CD4+ activated T cell

d. Resting lymphocytes (B cell, T cell)

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83)

The following statements are true for IgE, EXCEPT:

a. They bind to mast cells

b. They produce allergic reaction

c. Can cross the placental barrier

d. The least immunoglobulin in the plasma

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84) How many serotypes of HCV in the world?:

a. 6

b. 2

c. Many

d. 4

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85) Immunoglobulins do which of the following?:

a. Antigen binding

b. Complement fixation

c. All of the above

d. Opsonisation

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86) Which of the following is NOT a major feature (characteristic) of the adaptive immune
system?:

a. Diversity

b. Specificity

c. Improvement

d. Memory

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87) The azerophilic granule used to facilitate phagocytosis:

a. Parasite

b. Mycose

c. Bacteria

d. Virus

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88) Which immunoglobulin is used to produce vaccine:

a. IgA

b. IgM

c. IgE

d. IgG

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89)

Histamine is secreted by:

a. Epithelial cell

b. Mast cells

c. Red blood cells

d. White blood cells

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90) B and T cells are produced by stem cells located in:?:

a. Spleen

b. Bone marrow

c. Circulatery system

d. Liver

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91)

Class of immunoglobulins occurs :

a. Causes the histamine release

b. Binds complement

c. Immunizations, going from IgM to IgG

d. Mediates immunoglobulin class switching

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92) The function of major histocompatibility complex is:

a. Bind antibody for cytokine secretion

b. Bind epitope for presentation to T-cells

c. Degrade T4 and T8 polypeptides

d. Bind complement for cell lysis

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93)

Which immunoglobulin is the principal one found in secretions such as mucus :

a. IgA

b. IgG

c. IgM

d. IgD

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94) The following vaccines is used after exposure?:

a. Hypogammaglobulinemia

b. Varicella

c. Tetanus

d. TB

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95) B Cells are activated by?:

a. Antibody

b. Interferon

c. Memory cells

d. Antigen

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96) The first immunoglobulin secreted by B cells to make up memory cells is?:

a. IgG

b. IgA

c. IgD

d. IgM

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97) The natural passive immunity are characterized by?:

a. Kill vaccin Immune cell

b. Immunoglobulins

c. Placental transfert

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98) The function of cytokines are :

a. Production of complement

b. Bind to MHC class I

c. Regulation the immune cells

d. Specifically recognize antigens

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99) The following organs do not affect by hepatitis virus, EXCEPT:

a. Kidneys

b. Heart

c. Brain

d. Liver

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100) The average incubation period of Hepatitis A is?:

a. 15 days

b. 7 days

c. 30 days

d. 60 days

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101) The specific type of functional activity of a T-cell following antigen recognition is determined
by:

a. CD4 or CD8 can bind antigens

b. carbohydrate side chains

c. MHC class II presenting the antigen fragment

d. Antigen receptor

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102) The following statements are true for Class II MHC molecules, EXCEPT :

a. Presented antigen to Tc cells

b. Used to participate in Th function

c. Recognized by the CD4

d. Able to carry an antigen fragment

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103) The following answers are function of B cell, EXCEPT?:

a. Complement cascade

b. APC

c. Antibody secretion

d. Memory B cells

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104) Cytokines are produced by cells of the immune system in response to various antigen,
EXCEPT:

a. Opsonization antigen

b. Activate cell function

c. Facilitate cell lysis

d. Cause histamine release

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105)

The followings statement are TRUE, EXCEPT :

a. MHC Class I generally occur on all cells of the immune system

b. MHC Class 1 bind antigen fragments and are recognized by the Tc-cell receptor

c. MHC Class II bind antigen and are recognized by the T-cell receptor and the CD4

d. MHC Class II carrying antigen presented to cytotoxic T cells

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106)

The functional activity of the T-cell:

a. Occurs after recognition of an epitope

b. All answers

c. Is related with CD4 or CD8 associated polypeptides

d. Can be mediated through cytokines

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107) Which of the following technic is the best method to detect early infection of hepatitis?:

a. ELISA

b. RIA

c. Agglutination

d. PCR

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108) The tests below show that patient is already vaccinated against HBV?:

a. HBsAg negative

b. HBsAb positive

c. HBcAb negative

d. All answers

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109) Which of the following statements about leukocyte function is false?:

a. Eosinophils kill parasites

b. Eosinophils release histamine .

c. Leukocytes are cells of the immune response.

d. Neutrophils phagocytose pathogens .

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110) The following molecules can activate B cells to secrete antibody, EXCEPT:

a. Antigenic determinant

b. Antigen

c. Allergen

d. Hapten

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111) The J-chain of immunoglobulin is :

a. Made by T cells

b. Made only by epithelial cells

c. Present in IgM

d. Present in IgG

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112) The first antibody secreted by B cells during infection is?:

a. IgE IgA

b. IgM

c. IgG

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113) Molecule binding to their receptors at high affinity :

a. Cytokines

b. Antibody

c. All answer

d. Antigen

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114)

The following statements are true, EXCEPT:

a. IgA is a secretory immunoglobulin

b. IgE mediates hypersensitivity

c. IgM and IgG can fix complement

d. IgD provides passive immunity

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115) The following bonds is responsible for linking of antibody to its chains:

a. Disulfide bonds

b. Van der Waals forces

c. Hydrophobic forces

d. Hydrogen bonds

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116) Regulatory T cells (Treg cells), formerly known as ?:

a. Suppressor T cells

b. Natural T reg

c. Adaptive T reg

d. CD4+ T reg

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117)

The factor that dissociated the initiation of C1qrs in the classical pathway is:

a. Factor P

b. Factor F

c. C3-BP

d. C1-INH

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118) The following immunoglobulin has extra domain and long tail :

a. IgM

b. IgE

c. IgG

d. IgA

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119) The following receptor is for T cells?:

a. BCR

b. TCR

c. Scavenger receptor

d. Toll like receptor

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120)

The immunoglobulin Joining chain (J-chain) is:

a. Associated with IgM and IgA

b. Produced by mast cells

c. Produced by T-Cells

d. Associated with IgM and IgG

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121) Which lymphocyte are Large Granular Lymphocytes?:

a. Macropages

b. T cells

c. NK cells

d. B cells

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122)

All of the following are true for IgE molecules, EXCEPT:

a. They can fix complement.

b. They involved in allergic reactions.

c. They anti-parasitic immune responses.

d. They can cause the release of histamine.

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123) The C5 convertase of Alternative pathway is:

a. C4b2b3a

b. C4b2a4b

c. C3bBb3b

d. C4b2a3b

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124) The receptor BCR for an antigen on the membrane of B cell is?:

a. Bivalent

b. None about

c. Trivalent

d. Monovalent

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125) Biological properties of C5a are:

a. Attract and activate PMN

b. Anaphylactic much potent

c. All answers

d. Chimotactic activity

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126) The basic monomeric Immunoglobulin unit is:

a. Synthesized by a T-cell

b. Four polypeptide chains

c. One of five major classes

d. Four polypeptide chains and One of five major classes

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127) Which of the following statements about HBV is NOT correct?:

a. Hepato carcinoma

b. Can replicate

c. Parenteral route

d. RNA virus

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128) The drug to cure post exposure of HBV is?:

a. IgG

b. IgA

c. IgE

d. IgM

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129)

All of the following are true about antibodies, EXCEPT:

a. They fix complement.

b. They occur on the surface of B-lymphocyte

c. They are a single amino acid sequence

d. They are glycoproteins.

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130)

All of the following are true of antigen, EXCEPT:

a. They contain epitopes.

b. They will react with antibodies.

c. They contain antigenic determinants.

d. They contain paratopes

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131) The following statement is the basic monomeric immunoglobulin unit, EXCEPT:

a. Same protein type for all antibody classes

b. The receptor is TCR

c. Able to associate with J- chain to form multimers

d. Composed of glycoproptein chains

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132)

The type of an immunoglobulin is determined by:

a. The heavy chain

b. The light chain

c. The carbohydrate

d. The variable region

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133) The following cells of immune system cam make inflammation:

a. Mast cells and Basophils

b. Monocytes

c. Basophils

d. Mast cells

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134) The variable regions in the light chains participate in:

a. Epitope binding.

b. Fc receptor binding.

c. Interaction of the Fab with cytokines.

d. Affinity of the complement receptors.

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135) All of the following statements are true for the diagnosis of HBV infection, EXCEPT?:

a. Glucose test

b. Liver enzyme

c. Serological HBV

d. Bilirubin

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136) Which of the following virus is NOT transmitted through the parenteral route?:

a. Hepatitis A

b. Hepatitis C

c. Hepatitis B

d. Hepatitis D

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137) The following statement are for Target cell lysis and destruction, EXCEPT:

a. Complement binding to IgE which have bound to epitopes on the cell surface

b. Complement binding to IgG and IgM which have bound to epitopes on the target cell

c. Perforin released from antigen-specific cytotoxic T-cells

d. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

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138) The following characcteristic is common for T and b cells?:

a. have constant regions

b. Polypeptide chains

c. able to fix complement

d. Recognize antigen

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139)

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgE

b. IgA

c. IgM

d. IgG

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140)

One principal function of the Class I and Class II major histocompatibility complex is to:

a. Mediate immunoglobulin class

b. Stimulate production of interleukins

c. Help T cell for the recognition Antigen

d. Transduce the signal to the T-cell interior

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141) Which properties do the T-cell receptor and the antibody share in common:

a. Both are polypeptide chains

b. Both are able to fix complement

c. Both recognize antigen fragments

d. Both have constant regions

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142)

The major role of the complement C3b is to work in conjunction with:

a. Antibodies to opsonize cells

b. MHC for cell recognition

c. Antibodies to lyse cells antgen

d. T-cell for production of lymphokines

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143) The following answer is NOT true for interleukins?:

a. Regulation between cells

b. Produced by antigen

c. They are not in stock

d. Produced by T cells

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144)

The function of Natural Killer cell is:

a. Kill pathogen

b. Response to bacteria infection

c. Response to antibody

d. Damaged the target cell membrane

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145) The percentage of lymphocytes leave the thymus to become mature immunocompetent T
cells is?:

a. 10%

b. 2%

c. 90%

d. 98%

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146) The function of antibody produced by B cells are?:

a. Complement fixation

b. Opsonisation

c. Neutralisation

d. All answers

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147) Papain cleaves what region of immunoglobulin?:

a. Heavy chain

b. Hinge region

c. Heavy chain and Light chain

d. Light chain

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148) The tests below show that patient is susceptible to an HBV infection?:

a. HBsAb negative

b. HBcAb negative

c. All answers

d. HBsAg negative

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149) Intracellular pathogen is presented to the Tc by:

a. MHC I

b. MHC II

c. TH

d. Lymphocytes

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150) Which cell is Granulocyte:

a. Lymphocyte

b. Basophil

c. Monocyte

d. Macrophage

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151)

Which of the following is NOT a structural chain in class I MHC?:

a. β1

b. α1

c. β2 –microglobin

d. α2

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152)

All of the following are true with respect to IgE molecules, EXCEPT :

a. They can effect the release of histamine.

b. They will cross the placenta and fix complement)

c. They are the principal immunoglobulin class involved in allergic reactions.

d. They are involved in mediating anti-parasitic immune responses

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153) When hepatitis vaccin start to use since year?:

a. 1960

b. 1985

c. 2002

d. 199000%

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154)

All of the following are true, EXCEPT:

a. An epitope is a portion of an antigen

b. IgM antibody is pentamer

c. IgG antibody is pentavalent

d. The variable contain the antigen recognition site

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155) In chronic infection of hepatitis B, the antibody persists in the whole life is?:

a. HBsAg

b. HBcAb

c. HBcAg

d. HBsAb

156 / 321

156) The following answers is receptor for complement on immunoglobulins:

a. Hinge region

b. Heavy chain

c. Fc region

d. Fab region

157 / 321

157)

The followings statement are TRUE, EXCEPT:

a. MHC I presented on all cells of the immune

b. MHC I bind antigen and recognized by the Tc

c. MHC II carrying antigen presented to Tc

d. MHC II bind antigen and recognized by the Th

158 / 321

158)

Light chains are:

a. Have only a constant region

b. Reactive with antigen

c. Specific for each class of antibody

d. Not specific for each class of antibody

159 / 321

159) Which nonspecific defense cells specialize in attacking cancer cells and virus-infected cells?:

a. TH cells

b. B cells

c. NK cells

d. Macrophages

160 / 321

160) Which of the following require the Thymus?:

a. B cel apoptosis

b. T cells rogenitor

c. B cellsmaturation

d. T cells maturation

161 / 321

161) Which of the following organ is primarily infected by Hepatitis viruses?:

a. Lung

b. Intestines

c. Liver

d. Spleen

162 / 321

162)

Variable domains are:

a. Located at the N-terminal of heavy chains

b. Transported IgG across the placenta

c. Specific recognition of antigen

d. Needed to bind complement

163 / 321

163)

What is the term used to describe white blood cells migrating toward bacteria? :

a. Phagocytosis

b. Chemotaxis

c. Phototaxis

d. Zeiosis

164 / 321

164) Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Hepatitis B

b. Rabies

c. Polio

d. Pertussis

165 / 321

165) Lymphocytes that develop immunocompetence in the thymus are?:

a. T cells

b. LGL's

c. B cells

d. NK cells

166 / 321

166)

Which of the following is NOT true of interleukins:

a. They are able to bind antigen with a high level of specificity

b. They are cytokines which can be produced by various cells of the immune system.

c. They are hormones which allow one cell to communicate with another cell.

d. They are in need of receptors on the target cell in order to mediate their effects.

167 / 321

167) The Cytotoxic T cells kill the cells/molecules below:

a. Infected cells

b. Intracellular antigen

c. Extracellular antigen

d. Bacteria

168 / 321

168) The region of immunoglobulin(s) can be flexible:

a. Fc region

b. Heavy chain

c. Fab region

d. Hinge region

169 / 321

169) The following cells are proliferated from myloid progenitor :

a. TH1

b. Lymphocytes

c. Dendritic cells

d. B cells

170 / 321

170) Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis A virus

b. Hepatitis B virus

c. Hepatitis G virus

d. Hepatitis E virus

171 / 321

171) Which of the following is a β structural chain in class I MHC?:

a. β2 –microglobin

b. α2

c. β1

d. α1

172 / 321

172) The C5 convertase of Classic and Lectin pathway is:

a. C4b2a3b

b. C4b2a4b

c. C4b2b3a

d. C3bBb3b

173 / 321

173) The following statements are true for Class I MHC molecules, EXCEPT :

a. Tc cells kill an infected cells

b. Recognized by the CD8

c. On the APC cells membrane

d. Participated in Th function

174 / 321

174)

The light chains of antibodies are distinguished by:

a. Their variable region domains

b. The J-chains that bind to them

c. Their constant specific region

d. Kappa or lambda types

175 / 321

175) Identity the phagocytic cells from the following combinations:

a. Macrophage and neutrophil

b. Lymphocyte and eosinophil

c. Eosinophil and neutrophil

d. Macrophage and eosinophil

176 / 321

176) The following immunoglobulin is used to produe vaccine?:

a. IgG

b. IgA

c. IgG4

d. IgM

177 / 321

177) Clinical abnormalities of the Immune system can result from the activities below:

a. Neutrophils kill bacteria

b. Plasma cells secrete antibody

c. T cell secrete cytokine

d. Abnormal lymphocyte proliferation

178 / 321

178) The tetanus vaccine is prepare from ?:

a. Virulence antigen

b. Killed antigen

c. Toxin antigen

d. Inactivated antigen

179 / 321

179) Class II MHC proteins are :

a. Recognized by CD4 and Used to participate in helper function

b. Used to participate in helper function

c. Recognized by CD4

d. Recognized by CD8

180 / 321

180) The following immunoglobulin can opsonize antigen during acute phase infection?:

a. IgM

b. IgE IgA

c. IgG

181 / 321

181)

In the complement system, the classic pathway initiates by the complement :

a. C1qrs

b. C4

c. MBL

d. C5

182 / 321

182) Which lymphocyte response to HBV infectin?:

a. Th

b. Macrophage

c. B cells

d. Tc

183 / 321

183)

Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:

a. Botulism

b. Halitosis

c. Chemotaxis

d. Phagocytosis

184 / 321

184)

All of the following are true, EXCEPT:

a. IgG antibody is bivalent

b. The variable contain the antigen recognition site

c. An epitope is a portion of an antigen

d. IgM antibody is pentavalent

185 / 321

185) The following vaccines is not used in United State?:

a. Polio

b. Hepatitis A

c. Tuberculsis

d. Varicella

186 / 321

186) Which cells secreted most cytokine in innate immune:

a. Plasma cell

b. B lymphocyte

c. T lymphocyte

d. Macrophage

187 / 321

187) All of the following are function of IgG, EXCEPT :

a. Primary response to antigen

b. Activate complement

c. Cross placenta

d. Opsonize bacteries

188 / 321

188)

Complement deficiencies of C3b can cause:

a. Predisposition to SLE

b. Glucose oxidase deficiency

c. Overproduction of C2b

d. Bacterial infection

189 / 321

189) B cells recognised antigen presented by APC?:

a. Nonself – antigen

b. T-independent antigen

c. T-dependent antigen

d. Self – antigen

190 / 321

190) The tests below show that patient has an chronic infection of HBV?:

a. HBcAb positive

b. All answers

c. HBsAg positive

d. HBsAb negative

191 / 321

191)

The functional activity of the T-cell:

a. Can be mediated through cytokines

b. Is related with CD4 or CD8 associated polypeptides

c. Occurs after recognition of an epitope

d. Is related with CD4 or CD8 associated polypeptides, Occurs after recognition of an epitope, Can be mediated through cytokines

192 / 321

192) The disease below can cause by autoimmune:

a. Cancer

b. Thalassemia

c. SLE

d. Hepatitis

193 / 321

193)

Hyper variability regions are present in:

a. Dark chain

b. Heavy chain only

c. Light chain only

d. Heavy and light

194 / 321

194) The T-cell receptor is:

a. Secreted by the T-cell

b. Recognized antibody

c. Bivalent

d. Recognized antigen fragments

195 / 321

195) The fragment of Antigen is called:

a. Hapten

b. Immunogen

c. Immunoglbulin

d. Antigenic determinant

196 / 321

196) The following statement are true for Cytokines, EXCEPT:

a. Secreted by specialized cells

b. Are complement

c. Control and regulate the immune response

d. Lymphokines are cytokines

197 / 321

197)

All of the following are true with respect to IgM antibodies, EXCEPT :

a. They fix complement

b. They are glycoproteins

c. They mediate allergic reaction

d. They occur on the surface of lymphocytes

198 / 321

198) In chronic infection of hepatitis B, the antigen persists in the whole life are?:

a. HBeAg

b. All answers

c. HBsAg

d. HBcAg

199 / 321

199) The function of LGL cell is:

a. Response to bacteria infection

b. Kill pathogen

c. Response to antibody

d. Respose to tumor cells

200 / 321

200) The Natural Killer T Cells work in the immune system :

a. Adaptive immunity and Innate immunity

b. Innate immunity

c. Adaptive immunity

d. Link between Adaptive and Innate immune

201 / 321

201) All of these tests show that patient has been vaccinationated against HBV, EXCEPT?:

a. HBcAb Negative

b. HBsAg negative

c. IgM positive

d. HBsAb positive

202 / 321

202)

To stabilise the C3 convertase of the alternative pathway, the factors below are useful :

a. C1-INH

b. Factor P

c. C3-BP

d. Factor F

203 / 321

203) The following statement are function of immune system, EXCEPT:

a. Mediated the humoral and cellular response

b. Allow pathogen to infect the bod

c. Facilitated by T-cells

d. Can be facilitated by antibodies

204 / 321

204)

The followings statement are FALSE for Target cell lysis and destruction :

a. Perforin released from Tc

b. C3b fix to IgE which have epitopes

c. Tc recognizing specific epitopes

d. C3b fix to IgG and IgM which have epitopes

205 / 321

205) The vaccine prepared from living and inactivated microbe is considered as?:

a. Antibody

b. A toxoid

c. Atenuated vaccin

d. Denatured

206 / 321

206)

The immunoglobulin class which is the least abundant in the normal adult is :

a. IgE

b. IgG

c. IgA

d. IgD

207 / 321

207) The function of MHC class II is:

a. Recognized by the CD8

b. Presentation Ag to Th cell

c. Recognized by CD4

d. Unable to carry antigen fragment

208 / 321

208) Which of the following are true statements:

a. IgA can fix complement

b. IgD provides immunization

c. IgE lyses allergen

d. IgM and IgG can fix complement

209 / 321

209)

Skin is a________ barrier:

a. Anatomical

b. Phagocytic

c. Inflammatory

d. Physiological

210 / 321

210) The following tests show that patient got chronic infection of HCV?:

a. ALT elevated

b. IgM positive

c. ALT elevated and Anti-HCV positive

d. Anti-HCV positive

211 / 321

211) The component of immune system that can cause fever is :

a. Complement

b. Macrophage

c. Immunoglobulin

d. T lymphocytes

212 / 321

212) Light chains are :

a. Specific for each class of antibody

b. Reactive with antigen

c. Complement fixation

d. Have only a constant region

213 / 321

213) The first immunoglobulin response to the viral hepatitis A infection is?:

a. IgG

b. IgA

c. IgE IgM

214 / 321

214) The cells that have azerophilic granule to facilitate phagocytosis is:

a. Monocytes

b. Basophils

c. Neutrophils

d. Mast cells

215 / 321

215)

One principal function of complement is to:

a. Inactivate perforins

b. Bind antibodies attached to cell surfaces and to lyse these cells

c. Phagocytize antigens

d. Mediate the release of histamine

216 / 321

216)

Clinical abnormalities of the Immune system can result from the activities below, EXCEPT:

a. T cell secrete cytokine

b. Abnormal lymphocyte proliferation

c. Bacterial infection

d. HIV Infection

217 / 321

217)

Individuals unable to make the C4b would be expected to have frequent infections of the :

a. Diabetis

b. Liver disease

c. Thalassemia

d. Bacteria

218 / 321

218)

Thymus growth occurs up to:

a. 17 years

b. 5 years

c. 30 years

d. 12 years

219 / 321

219)

Clinical abnormalities of the Immune system can result from the following statement, EXCEPT:

a. T cells proliferation

b. Abnormal lymphocyte proliferation

c. Deficiency diseases

d. HIV Infection

220 / 321

220) Platelets can produce by those organs:

a. Thymus

b. Spleen

c. Liver

d. Bone marrow

221 / 321

221)

Individuals make up over C4a would be expected to have:

a. Diabetis

b. Anaphylaxia

c. Bacteria

d. Liver disease

222 / 321

222)

In the complement system, the lytic pathway initiated by the complement :

a. C4

b. MBL

c. C1qrs

d. C5

223 / 321

223) Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgM

b. IgE:

c. IgG

d. IgA

224 / 321

224) Which of the following is NOT a structural chain in class II MHC?:

a. β 1

b. α2

c. α1

d. α3

225 / 321

225)

Which of these cell types can play a primary role in attacking and killing cancer cells?:

a. T cell

b. Mast cell

c. Platelet

d. Cytotoxic

226 / 321

226)

Which of the following is NOT true of interleukins?:

a. Produced by cells of the immune system.

b. Relation between cells of immune system

c. They bind antigen with a high specificity

d. They have receptors on the target cell.

227 / 321

227) Class II MHC proteins are:

a. Used to kill cytotoxic T-cells

b. Not able to carry an epitope

c. Participate in T helper function

d. Recognized by the CD8 protein

228 / 321

228) How many receptors for antigen on the surface of B lymphocyte:

a. 1

b. 4

c. 10

d. 2

229 / 321

229)

In the alternative pathway of the complement system, the factors below are useful to prevent the generation of C3 convertase :

a. C3-BP

b. Factor P

c. C1-INH

d. Factor F

230 / 321

230)

Superantigens presented to T cells by :

a. Mast cell

b. Monocyte

c. B cell

d. APC

231 / 321

231) T- independent antigen presented to the following lymphocyte?:

a. TH cells

b. TH1 cell

c. B cells

d. Tc cells

232 / 321

232)

Humoral immunity consists of:

a. Immunoglobulins

b. Normal cells

c. Cytotoxic cells

d. Pathological cells

233 / 321

233) The family of Hepatitis B virus is named:

a. CMV

b. Retrovirus

c. Hepadnavirus

d. Flavivirus

234 / 321

234) Class II MHC molecule works for?:

a. An antigen fragment

b. B cell activation

c. T helper function

d. Tc function

235 / 321

235) The following statements are true for the antigenic determinant :

a. Is paratope

b. Is paratope and Small part of the antigen

c. Small part of the antigen

d. Is the combining site of an antibody

236 / 321

236)

Complements are chemically:

a. Glycoproteins

b. Glycogens

c. Proteins

d. Lipoproteins

237 / 321

237)

IgE produce by :

a. T-cells

b. Plasma cells

c. B-cells

d. Mast cells

238 / 321

238) The screening test for HBV infection is?:

a. HBsAb

b. HBcAg

c. HBcAb

d. HBsAg

239 / 321

239) In a chronic infection of Hepatitis B, the typical serologic course are :

a. HBsAg and HBcAb

b. HBcAb

c. HBsAg

d. HBsAb

240 / 321

240)

The following statements are true for Antibodies:

a. Contain heavy and light chains

b. Are carbohydrates

c. Are made from alpha and beta chains

d. Contain no carbohydrate

241 / 321

241)

Which cell is directly secreted immunoglobulin:

a. T lymphocyte

b. B lymphocyte

c. Macrophage

d. Plasma cell

242 / 321

242)

Which of the following statements about leukocyte function is false?:

a. Leukocytes are involved in the immune response.

b. Neutrophils engulf damaged cells and pathogens by phagocytosis.

c. Eosinophils deliver toxic granules to kill parasites. They are also involved in allergic reactions.

d. Macrophages are phagocytic cells that are involved in the adaptive response.

243 / 321

243) Each of the following statement is a characteristic of antibodies, EXCEPT:

a. They are phagocytes

b. They have specific receptor for antigen

c. They contain variable region

d. They have four glycoprotein chains

244 / 321

244) Biological effect of Complement C3a is:

a. Anaphylaxis

b. Opsonisation

c. Edema

d. Phagocytosis

245 / 321

245) Which of the following are mechanisms for neutrophil phagocytosis:

a. Azerophilic granules

b. Hydrolytic enzymes

c. defensins

d. Azerophilic granules and defensins

246 / 321

246)

In acute infection of Hepatitis B, the typical serologic course are:

a. HBcAb

b. HBsAg

c. HBcAg

d. HBsAb

247 / 321

247) The answer below is/are artificial active immunization?:

a. Exposure to the infections

b. Killed organisms

c. Killed organisms and Attenuated organisms

d. Attenuated organisms

248 / 321

248) The following cells are cells mediated immunity in adaptive immune response?:

a. All answers

b. B cells

c. T cells

d. Tc cells

249 / 321

249)

The J-chain is :

a. For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

b. Facilitates secretion of pentameric lgM

c. For immunoglobulin multimer formation

d. Made only by epithelial cells

250 / 321

250) All of these tests show that patient has been infected with HBV, EXCEPT?:

a. HBcAb positive

b. HBcAg positive

c. HBsAg negative

d. HBsAb positive

251 / 321

251)

Complement Deficiencies of C5, C6, C7, C8 and C9 can causes :

a. Anaphylaxia

b. Lack of opsonisation

c. Inability to attack the Gram-negative bacteria

d. Susceptibility to pyogenic bacterial infections

252 / 321

252) Which antigen is direct presented to B cell?:

a. T- Independent antigen

b. T- dependent antigen

c. Self- antigen

d. Non self- antigen

253 / 321

253)

What’s a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:

a. Complement

b. MHC II molecule

c. Peptide

d. Antigen

254 / 321

254)

T-cell antigen receptors are distinguished from antibodies by which of the following :

a. T-Cell receptors bind various cytokines

b. T-Cell receptors bind complement to lyse cells

c. T-cell receptors must interact with antigen

d. T-Cell receptors are glycosylated

255 / 321

255) The cancer of T cells are called?:

a. Hodgkin lymphoma

b. All answers

c. Non-Hodgkin lymphoma

d. Extranodal T cell lymphoma

256 / 321

256)

Which of the followings are TRUE regarding an Immune response :

a. The T4 secrete antibody

b. The function of the T3 complex is signal to the cell's interior after recognition the antigen

c. The T4 serves an auxiliary role with MHC class I in helper cell reactions

d. The T8 serves an auxiliary role with MHC class II in cytotoxic reactions

257 / 321

257) The variable regions in the heavy chains participate in:

a. Complement receptor

b. Cytokine receptor

c. Antigen receptor

d. Cellular receptor

258 / 321

258) The rabic vaccin is used to?:

a. Prevent rabie infection

b. Cure rabie infection

c. Cure tetanus infection

d. Prevent tetanus infection

259 / 321

259) Which of the followings are TRUE regarding an Immune response:

a. The T8 support MHC II in cytotoxic reactions

b. The T4 support MHC class I in helper reactions

c. The T3 complex is signal to the cell's interior to recognize antigen

d. The T4 secrete antibody

260 / 321

260) The factor that stabilize C3 convertase of alternative pathway is :

a. DAF

b. Factor I

c. Factor P

d. Factor H

261 / 321

261)

All of the following are true about antibodies, EXCEPT:

a. They fix complement.

b. They occur on the surface of B-lymphocyte

c. They are polypeptide

d. They are glycoproteins.

262 / 321

262) The following vaccines is Microbial Fragment Vaccines?:

a. Clostridium tetani

b. Hepatitis A

c. Varicella

d. Polio

263 / 321

263) The following statement are for Class I MHC proteins, EXCEPT:

a. Able to carry an antigen fragment

b. Killed target cells by Tc cells

c. Participate in T helper function

d. Recognized by the CD8 protein

264 / 321

264) The incubation period of HBV in the body is?:

a. 45-180 days

b. 30-90 days

c. 60-100 days

d. 30-60 days

265 / 321

265)

The following statement is for MHC Class I:

a. Used to kill by cytotoxic T-cells

b. Not able to carry an antigen fragment

c. Recognized by the CD8 protein

d. Participated in helper function

266 / 321

266)

The T3 complex of the T-cell receptor:

a. Causes the histamine

b. Mediates Immunoglobulin class switching

c. To transduce a signal to the cell's interior

d. Binds complement

267 / 321

267) The following cells of immune system cam make IgE:

a. Mast cells and Eosinophils

b. Eosinophils

c. Mast cells

d. Monocytes

268 / 321

268) The following activity is indicated T cell cytotoxic:

a. Epitope presented to CD4

b. MHC-I restricted

c. B cell activation

d. MHC-II restricted

269 / 321

269)

Which of the followings are NOT TRUE regarding an immune response:

a. The T4 serves an auxiliary role with MHC class II proteins in helper cell reactions

b. The T8 serves an auxiliary role with MHC class I proteins in cytotoxic reactions

c. Lymphokines are produced by T-cells in response to antigen presentation by antibody

d. The principal function of the T3 complex is signal transduction to the cell's interior

270 / 321

270)

The function of immune system is to response:

a. Can be facilitated by antibodies

b. Mediated the humoral and cellular immune system

c. Facilitated by T-cells

d. All answers

271 / 321

271) The following antigen activate 25% of T cells:

a. Virus

b. HIV

c. Mycose

d. Staphylococus toxin

272 / 321

272) The function of T cytotoxic lymphocyte is?:

a. Lyse bacterie

b. Lyse target cell

c. Lyse paasite

d. Lyse pathogen

273 / 321

273)

One principal function of the Class I and Class II major histocompatibility complex is to :

a. Present antigen for recognition by the T-cell receptor

b. Transduce the signal to the T-cell interior

c. Mediate immunoglobulin class

d. Stimulate production of interleukins

274 / 321

274) The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBcAg

b. HBcAb

c. HBsAb

d. HBsAg

275 / 321

275) Which of the following immunoglobulin is first synthesized in an immune system to response
an pathogen?:

a. IgG

b. IgA

c. IgE

d. IgM

276 / 321

276)

Class II MHC are :

a. Recognized by the CD4 protein

b. Used to kill by cytotoxic T-cells

c. Used to participate in cytotoxic function

d. Not able to carry an antigen fragment

277 / 321

277) The classical pathway of the complement is initiated by:

a. C3

b. MBL

c. C1qrs

d. Factor B

278 / 321

278) Which of the following statement is related to IgG physiology in humans?:

a. It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.

b. It is confined to the bloodstream, giving the host protection against blood-borne pathogens.

c. Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.

d. IgG crosses the placental barrier, and thereby provides passive immunity to the fetus.

279 / 321

279) The hapten carrier conjugate can activate B cells to secrete antibody :

a. Antigenic determinant

b. Immunoglobulin-Epitope

c. Immunoglobulin

d. Antigen

280 / 321

280) Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis D virus

b. Hepatitis B virus

c. Hepatitis C virus

d. Hepatitis A virus

281 / 321

281) Which kind of cells worked in innate immune system and response to the tumor cells?:

a. Macropages

b. NK cells

c. T cells

d. B cells

282 / 321

282) Which of these factors can cause hepatitis?:

a. All of the above

b. Malfunctioning immune system

c. Viruses

d. Drugs and alcohol

283 / 321

283) The first screening test to detect HBV infection is?:

a. HBsAb

b. HBsAg

c. HBcAb

d. HBcAg

284 / 321

284)

Each of the following is a characteristic of antibodies, EXCEPT :

a. They are proteins with variable and constant regions

b. They are only secreted by T-cells

c. They combine specifically with antigen

d. They contain carbohydrates

285 / 321

285)

Organ transplantation of human from one place to another is called:

a. Xeno-graft

b. Allo-graft

c. Autograft

d. ISO-graft

286 / 321

286) The immunoglobulin(s) that have long hinge region are/is:

a. IgG1

b. IgG3

c. IgG2

d. IgG4

287 / 321

287)

The Biological Effects of C3b is :

a. Susceptibility to bacterial infections

b. Phagocyte activation

c. Anaphylaxia

d. Lack of opsonisation

288 / 321

288) T cells secreted cytokine to activate T cells neighbering, This phenomen is called?:

a. Endocrine

b. Paracrine

c. None about

d. Autocrine

289 / 321

289) Which of the following components of the innate immune system involves the release of
histamine?:

a. Neutrophil

b. Tissue mast cell

c. Eosinophil

d. Macrophage

290 / 321

290) The TH cells produced cytokines to response the viral infection?:

a. Interferon

b. Chimokine

c. IL-2

d. Tumor necrose factor

291 / 321

291) Which type of cell destroys body cells that cause by infection?:

a. Cytotoxic T cells

b. Memory T cells

c. Memory B cells

d. Plasma B cells

292 / 321

292)

The immunoglobulin class which is the second abundant in the normal adult is:

a. IgD

b. IgA

c. IgE

d. IgG

293 / 321

293) These cytokines secreted by T helper cell?:

a. IL-2

b. Chimokine

c. Interferon

d. TNF-α

294 / 321

294) The CD marker of B cells are?:

a. CD19 and CD21

b. CD3 and CD54

c. CD3 and CD8

d. CD16 and CD56

295 / 321

295) Biological effect of Complement C4a is regulated by:

a. Factor I

b. C4-BP

c. Factors H & I

d. C3-INA

296 / 321

296) The following statements are true for Antibodies, EXCEPT :

a. Fc receptor for complement

b. Extra domain for IgM

c. Made of heavy and light chains

d. Receptors for antigens are monovalent

297 / 321

297) The major function of major histocompatibility complex for antigen intracellular is:

a. Presentation antigen to Th-cells

b. Presentation antigen to Tc-cells

c. Degrade Th and Tc

d. Bind complement for cell lysis

298 / 321

298) The initial complement component that is bound by complement-fixing antibodies is:

a. C3b

b. C1s

c. C1q

d. C5a

299 / 321

299)

The major role of the complement system is to work in conjunction with:

a. MHC for cell recognition

b. Antibodies to opsonize cells

c. Antibodies to lyse cells via the C8 and C9 components

d. T-cell receptor for production of lymphokines

300 / 321

300) Immunity acquired after an infection is?:

a. Response immunity

b. Innate immunity

c. Passive immunity

d. Active immunity

301 / 321

301) Biological effect of Complement C5a is:

a. Opsonisation

b. Inflammation

c. Phagocytosis

d. Neutrophil activation

302 / 321

302) Cell mediated immunity in adaptive immune is carried out by?:

a. T cells

b. B cells

c. Antigen

d. Antibody

303 / 321

303) The following answer is the function of IgG, EXCEPT :

a. Cross placenta

b. Opsonize bacteries

c. Primary response to antigen

d. Activate complement

304 / 321

304) All of the following are true, EXCEPT :

a. An epitope is a fragment of a macromolecule

b. An antigenic determinant is a paratope

c. The variable regions contain the antigen recognition site

d. The class of an immunoglobulin is determined by its heavy chain

305 / 321

305)

Graft between identical twins is called:

a. Iso graft

b. Xeno-graft

c. Auto graft

d. Allograft

306 / 321

306)

In the alternative pathway of the complement system, the factors below are useful to stabilise the generation of C3 convertase :

a. Factor P

b. Factor F

c. C3-BP

d. C1-INH

307 / 321

307) Tumor Necrose Factor (TNF) produce by:

a. Macrophage and Tc

b. Neutrophil

c. Macrophage

d. Tc

308 / 321

308) Which part of antibody lack of constant domain:

a. CH

b. CL and CH

c. CL

d. VL

309 / 321

309) The following statements are true for Class III MHC molecules, EXCEPT :

a. On the APC cells membrane

b. Tc cells kill an infected cells

c. Recognized by the CD8

d. Transport protein

310 / 321

310) Antigen-antibody reactions can result in the following:

a. Killed antigen

b. All answers

c. Virus neutralization

d. Complement fixation

311 / 321

311) The function of Class III MHC proteins are :

a. Lyse antigen

b. Recognized antigen by CD8

c. Recognized antigen by CD4

d. Transport complement protein

312 / 321

312) Which of the immune cells/molecules are effective to neutralise and opsonse extracellular
pathogens?:

a. B cells

b. Antibodies

c. Complement

d. T cells

313 / 321

313)

Immunoglobulins are chemically:

a. Glycogens

b. D. Lipo-proteins

c. Glycoproteins

d. Glycolipids

314 / 321

314)

What distinguishes helper T-cells from cytotoxic T-cells :

a. Helper cells recognize antigen complexed with MHC class I molecules

b. Cytotoxic cells recognize antigen complexed with MHC class I molecules

c. Cytotoxic cells recognize antigen complexed with MHC class I molecules and. Helper cells recognize antigen complexed with MHC class II molecules

d. Helper cells recognize antigen complexed with MHC class II molecules

315 / 321

315)

Which of the following is antiviral:

a. Lysozyme

b. Hormone

c. Interferon

d. Protein

316 / 321

316) Which type of antibody is MOST effective in activating complement?:

a. IgG2

b. IgG1

c. IgM

d. IgG3

317 / 321

317) How many receptors for antigen on the surface of T lymphocyte:

a. 1

b. 4

c. 10

d. 2

318 / 321

318) The following answer is the function of IgM, EXCEPT :

a. Activate complement

b. Opsonize bacteries

c. Primary response to antigen

d. Cross placenta

319 / 321

319) How many percentage of chronic HBV infection can lead to Cirrhosis?:

a. 10%

b. 25%

c. 50%

d. 15%

320 / 321

320) The following answer is Super antigen:

a. Mycose

b. Virus

c. Staphylococus toxin

d. HIV

321 / 321

321) The following diseases can be prevented by vaccination?:

a. Hepatitis A and B

b. Hepatitis D and C

c. Hepatitis C and E

d. Hepatitis B and C

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