Immunology Preparation (Pr. Kiet Vannseth)

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Which of the followings are TRUE regarding an Immune response :

a. The T4 secrete antibody

b. The T4 serves an auxiliary role with MHC class I in helper cell reactions

c. The function of the T3 complex is signal to the cell's interior after recognition the antigen

d. The T8 serves an auxiliary role with MHC class II in cytotoxic reactions

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2) Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis G virus

b. Hepatitis B virus

c. Hepatitis E virus

d. Hepatitis A virus

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3) Lymphocytes that develop immunocompetence in the thymus are?:

a. LGL's

b. NK cells

c. B cells

d. T cells

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4) The following viral hepatitis is enteric hepatitis?:

a. Heepatitis C

b. Hepatitis A

c. Hepatitis B

d. Hepatitis D

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5) The first antibody secreted by B cells during infection is?:

a. IgG

b. IgM

c. IgE IgA

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6) Molecule binding to their receptors at high affinity :

a. Cytokines

b. All answer

c. Antigen

d. Antibody

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7) Pepsin cleaves what region of immunoglobulin?:

a. Light chain

b. Hinge region

c. Heavy chain and Light chain

d. Heavy chain

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8) The T-cell receptor is:

a. Bivalent

b. Recognized antigen fragments

c. Secreted by the T-cell

d. Recognized antibody

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9) Which of the following is NOT a major feature (characteristic) of the adaptive immune
system?:

a. Memory

b. Diversity

c. Improvement

d. Specificity

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10) The following hepatitis can be prevented by vaccination :

a. Hepatitis B and C

b. Hepatitis C and E

c. Hepatitis D and C

d. Hepatitis A and B

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11) The pathway of the complement that can lyse bacteria is:

a. Alternative pathway

b. Lectin pathway

c. Lytic pathway

d. Classical pathway

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12)

Class II MHC are :

a. Used to kill by cytotoxic T-cells

b. Used to participate in cytotoxic function

c. Recognized by the CD4 protein

d. Not able to carry an antigen fragment

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13) The function of cytokines are :

a. Bind to MHC class I

b. Production of complement

c. Specifically recognize antigens

d. Regulation the immune cells

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14)

Which of the following immunoglobulin can across placenta with the highest concentration?:

a. IgG4

b. IgG3

c. IgG2

d. IgG1

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15) The following answer is the function of IgG, EXCEPT :

a. Activate complement

b. Cross placenta

c. Opsonize bacteries

d. Primary response to antigen

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16) The following statements are true for Class III MHC molecules, EXCEPT :

a. Tc cells kill an infected cells

b. Recognized by the CD8

c. Transport protein

d. On the APC cells membrane

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17) Biological effect of Complement C3a is:

a. Opsonisation

b. Edema

c. Anaphylaxis

d. Phagocytosis

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18)

Organ transplantation of human from one place to another is called:

a. Autograft

b. ISO-graft

c. Xeno-graft

d. Allo-graft

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19)

IgE produce by :

a. T-cells

b. Plasma cells

c. B-cells

d. Mast cells

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20)

T-cell receptors or antibodies react with antigens:

a. Because both 'have light chain and heavy chain polypeptides

b. Cause histamine release

c. Because they have specific receptors for antigen

d. Because both are made by lymphocytes

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21) The CD marker of B cells are?:

a. CD3 and CD54

b. CD19 and CD21

c. CD3 and CD8

d. CD16 and CD56

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22) Which of these factors can cause hepatitis?:

a. All of the above

b. Malfunctioning immune system

c. Drugs and alcohol

d. Viruses

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23)

All of the following are true, EXCEPT:

a. An epitope is a portion of an antigen

b. IgG antibody is bivalent

c. The variable contain the antigen recognition site

d. IgM antibody is pentavalent

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24) In a chronic infection of Hepatitis B, the typical serologic course are :

a. HBsAg

b. HBsAb

c. HBsAg and HBcAb

d. HBcAb

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25) Antigen-antibody reactions can result in the following:

a. All answers

b. Virus neutralization

c. Killed antigen

d. Complement fixation

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26) Biological properties of C5a are:

a. All answers

b. Anaphylactic much potent

c. Attract and activate PMN

d. Chimotactic activity

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27) The following answers are true for IgM antibodies, EXCEPT:

a. Pentametric form

b. Fix complement

c. Cause of allergy

d. Anti infectious

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28) All of the following are function of IgG, EXCEPT :

a. Activate complement

b. Cross placenta

c. Opsonize bacteries

d. Primary response to antigen

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29) T- independent antigen presented to the following lymphocyte?:

a. TH1 cell

b. TH cells

c. Tc cells

d. B cells

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30) The following statement is the basic monomeric immunoglobulin unit, EXCEPT:

a. Composed of glycoproptein chains

b. Able to associate with J- chain to form multimers

c. The receptor is TCR

d. Same protein type for all antibody classes

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31) Which cell is T helper:

a. CD8

b. CD14

c. CD15

d. CD4

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32)

The following statements are not true for Immunoglobins

a. All have receptors for complement

b. Possess both variable and constant regions

c. They have Fab

d. Five major classes of immunoglobulin

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33) The percentage of lymphocytes leave the thymus to become mature immunocompetent T
cells is?:

a. 90%

b. 98%

c. 2%

d. 10%

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34) Which of the following require the Thymus?:

a. B cellsmaturation

b. B cel apoptosis

c. T cells rogenitor

d. T cells maturation

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35)

The function of Natural Killer cell is:

a. Response to bacteria infection

b. Kill pathogen

c. Damaged the target cell membrane

d. Response to antibody

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36) Which of the following is NOT a structural chain in class II MHC?:

a. α3

b. α1

c. β 1

d. α2

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37) Which part of antibody lack of constant domain:

a. CL and CH

b. CL

c. VL

d. CH

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38) The function of major histocompatibility complex for antigen in the cytosol is:

a. Presentation antigen to Tc-cells

b. Presentation antigen to Th-cells

c. Transport protein

d. Bind complement for cell lysis

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39) Clinical abnormalities of the Immune system can result from the activities below:

a. Plasma cells secrete antibody

b. Abnormal lymphocyte proliferation

c. Neutrophils kill bacteria

d. T cell secrete cytokine

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40) B and T cells are produced by stem cells located in:?:

a. Bone marrow

b. Liver

c. Circulatery system

d. Spleen

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41) The class of an immunoglobulin is determined by:

a. The heavy chain

b. The light chain

c. Class I and II MHC

d. The antigen

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42)

One principal function of complement is not true:

a. Activate perforins

b. Lyse target cells

c. Mediate the release of histamine

d. Phagocytize antigens

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43)

The type of an immunoglobulin is determined by:

a. The variable region

b. The heavy chain

c. The light chain

d. The carbohydrate

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44) The family of hepatitis C virus is?:

a. Ribovirus

b. Rotavirus

c. Flavivirus

d. Hepanavirus

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45) The classical pathway of the complement is initiated by:

a. MBL

b. C1qrs

c. Factor B

d. C3

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46) All of these tests show that patient has been infected with HBV, EXCEPT?:

a. HBsAb positive

b. HBcAb positive

c. HBsAg negative

d. HBcAg positive

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47) Which of the following DOES NOT play a role in antigen presentation:

a. MHC class III molecules

b. MHC class II molecules

c. Complement

d. MHC class I molecules

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48) The answer below is/are artificial active immunization?:

a. Exposure to the infections

b. Attenuated organisms

c. Killed organisms and Attenuated organisms

d. Killed organisms

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49)

Complement Deficiencies of C5, C6, C7, C8 and C9 can causes :

a. Lack of opsonisation

b. Inability to attack the Gram-negative bacteria

c. Anaphylaxia

d. Susceptibility to pyogenic bacterial infections

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50)

Which of the followings are NOT TRUE regarding an immune response:

a. Lymphokines are produced by T-cells in response to antigen presentation by antibody

b. The principal function of the T3 complex is signal transduction to the cell's interior

c. The T8 serves an auxiliary role with MHC class I proteins in cytotoxic reactions

d. The T4 serves an auxiliary role with MHC class II proteins in helper cell reactions

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51) The first immunoglobulin response to the viral hepatitis A infection is?:

a. IgA

b. IgE IgM

c. IgG

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52) The following statement are function of immune system, EXCEPT:

a. Can be facilitated by antibodies

b. Allow pathogen to infect the bod

c. Mediated the humoral and cellular response

d. Facilitated by T-cells

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53) Cell mediated immunity in adaptive immune is carried out by?:

a. B cells

b. T cells

c. Antigen

d. Antibody

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54) How many receptors for antigen on the surface of T lymphocyte:

a. 4

b. 1

c. 2

d. 10

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55) The C5 convertase of Classic and Lectin pathway is:

a. C4b2a4b

b. C4b2a3b

c. C3bBb3b

d. C4b2b3a

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56)

Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:

a. Chemotaxis

b. Halitosis

c. Phagocytosis

d. Botulism

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57) The following vaccines are Live Attenuated Vaccines, EXCEPT?:

a. Tetanus

b. Varicella

c. Hepatitis A

d. Polio

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58) The screening test for HBV infection is?:

a. HBsAb

b. HBsAg

c. HBcAb

d. HBcAg

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59) Which immunoglobulin is used to produce vaccine:

a. IgM

b. IgE

c. IgA

d. IgG

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60) The Complement that gives Anaphylotoxin much potent is:

a. C2b

b. C3a

c. C4a

d. C5a

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61) Identity the phagocytic cells from the following combinations:

a. Lymphocyte and eosinophil

b. Eosinophil and neutrophil

c. Macrophage and neutrophil

d. Macrophage and eosinophil

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62) B cells recognised antigen presented by APC?:

a. Nonself – antigen

b. T-dependent antigen

c. Self – antigen

d. T-independent antigen

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63) The following cells of immune system cam make inflammation:

a. Mast cells and Basophils

b. Monocytes

c. Mast cells

d. Basophils

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64)

Light chains are:

a. Specific for each class of antibody

b. Not specific for each class of antibody

c. Have only a constant region

d. Reactive with antigen

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65)

Which of the following statements about leukocyte function is false?:

a. Macrophages are phagocytic cells that are involved in the adaptive response.

b. Eosinophils deliver toxic granules to kill parasites. They are also involved in allergic reactions.

c. Neutrophils engulf damaged cells and pathogens by phagocytosis.

d. Leukocytes are involved in the immune response.

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66) The receptor BCR for an antigen on the membrane of B cell is?:

a. Bivalent

b. None about

c. Monovalent

d. Trivalent

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67) The following statements are true for Class II MHC molecules, EXCEPT :

a. Recognized by the CD4

b. Presented antigen to Tc cells

c. Used to participate in Th function

d. Able to carry an antigen fragment

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68)

The following statements are true for Antibodies

a. Are carbohydrates

b. Are made from alpha and beta chains

c. Have variable region

d. Contain cytoplasmic region

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69) The region of immunoglobulin(s) can be flexible:

a. Hinge region

b. Heavy chain

c. Fab region

d. Fc region

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70) The tests below show that patient is susceptible to an HBV infection?:

a. HBcAb negative

b. All answers

c. HBsAb negative

d. HBsAg negative

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71)

The immunoglobulin class which is the second abundant in the normal adult is:

a. IgE

b. IgG

c. IgA

d. IgD

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72) Biological effect of Complement C4a is regulated by:

a. C4-BP

b. Factors H & I

c. Factor I

d. C3-INA

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73)

All of the following are true about antibodies, EXCEPT:

a. They occur on the surface of B-lymphocyte

b. They are glycoproteins.

c. They fix complement.

d. They are polypeptide

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74) Which of the following virus is NOT transmitted through the parenteral route?:

a. Hepatitis D

b. Hepatitis A

c. Hepatitis C

d. Hepatitis B

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75) Which nonspecific defense cells specialize in attacking cancer cells and virus-infected cells?:

a. B cells

b. Macrophages

c. TH cells

d. NK cells

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76)

Variable domains are:

a. Needed to bind complement

b. Located at the N-terminal of heavy chains

c. Specific recognition of antigen

d. Transported IgG across the placenta

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77) The Immunoglobulins are secreted by:

a. Macrophages

b. Plasma cells

c. B-cells

d. T-cells

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78) Which of the following organ is primarily infected by Hepatitis viruses?:

a. Lung

b. Liver

c. Spleen

d. Intestines

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79) The region of immunoglobulin term: Binds to various cellular receptors and to complement:

a. Fc region

b. Fab region

c. Heavy chain

d. Light chain

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80) In chronic infection of hepatitis B, the antigen persists in the whole life are?:

a. HBcAg

b. All answers

c. HBeAg

d. HBsAg

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81) The Cytotoxic T cells kill the cells/molecules below:

a. Bacteria

b. Extracellular antigen

c. Infected cells

d. Intracellular antigen

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82)

Hyper variability regions are present in:

a. Heavy and light

b. Light chain only

c. Dark chain

d. Heavy chain only

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83) The hapten carrier conjugate can activate B cells to secrete antibody :

a. Immunoglobulin-Epitope

b. Antigenic determinant

c. Immunoglobulin

d. Antigen

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84)

The light chains of antibodies are distinguished by:

a. Their constant specific region

b. Their variable region domains

c. Kappa or lambda types

d. The J-chains that bind to them

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85)

Which of the following is NOT true of interleukins?:

a. Relation between cells of immune system

b. They bind antigen with a high specificity

c. Produced by cells of the immune system.

d. They have receptors on the target cell.

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86) The function of antibody produced by B cells are?:

a. Neutralisation

b. All answers

c. Complement fixation

d. Opsonisation

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87) The following cells are cells mediated immunity in adaptive immune response?:

a. All answers

b. B cells

c. T cells

d. Tc cells

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88) Each of the following statement is a characteristic of antibodies, EXCEPT:

a. They have specific receptor for antigen

b. They are phagocytes

c. They have four glycoprotein chains

d. They contain variable region

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89)

To stabilise the C3 convertase of the alternative pathway, the factors below are useful :

a. Factor F

b. C1-INH

c. Factor P

d. C3-BP

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90) Cytokines are produced by cells of the immune system in response to various antigen,
EXCEPT:

a. Activate cell function

b. Cause histamine release

c. Opsonization antigen

d. Facilitate cell lysis

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91) The following immunoglobulin has extra domain and long tail :

a. IgM

b. IgG

c. IgE

d. IgA

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92)

The functional activity of the T-cell:

a. Occurs after recognition of an epitope

b. All answers

c. Is related with CD4 or CD8 associated polypeptides

d. Can be mediated through cytokines

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93)

Immunoglobulins are chemically:

a. Glycolipids

b. D. Lipo-proteins

c. Glycogens

d. Glycoproteins

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94) The following answer is NOT true for interleukins?:

a. They are not in stock

b. Regulation between cells

c. Produced by antigen

d. Produced by T cells

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95) The drug to cure post exposure of HBV is?:

a. IgE

b. IgA

c. IgM

d. IgG

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96) All of the following statements are true for the diagnosis of HBV infection, EXCEPT?:

a. Bilirubin

b. Serological HBV

c. Liver enzyme

d. Glucose test

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97)

Thymus growth occurs up to:

a. 17 years

b. 12 years

c. 30 years

d. 5 years

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98)

Complements are chemically:

a. Glycogens

b. Proteins

c. Lipoproteins

d. Glycoproteins

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99)

Which of the following represent immune system dysfunctions:

a. T cells proliferation

b. Facilitated by antibodies

c. Mast cells release histamine

d. Severe immunodeficiency

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100) All of the following are the type RNA virus, EXCEPT?:

a. Hepatitis B

b. Hepatitis E

c. Hepatitis A

d. Hepatitis C

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101) All of the following are a part of innate immune respond, EXCEPT :

a. Pathways of complement activation

b. Macrophage secrete cytokines

c. T cells secrete antibody

d. Natural Killer cells

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102) T cells secreted cytokine to activate T cells neighbering, This phenomen is called?:

a. Autocrine

b. Paracrine

c. None about

d. Endocrine

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103)

Which immunoglobulin is the principal one found in secretions such as mucus :

a. IgA

b. IgD

c. IgG

d. IgM

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104)

The factor that dissociated the initiation of C1qrs in the classical pathway is:

a. Factor P

b. C3-BP

c. Factor F

d. C1-INH

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105) The following immunoglobulin can opsonize antigen during acute phase infection?:

a. IgE IgA

b. IgM

c. IgG

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106) Which organ does hepatitis affect?:

a. Heart

b. Liver

c. Brain

d. Kidneys

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107) Platelets can produce by those organs:

a. Liver

b. Thymus

c. Spleen

d. Bone marrow

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108) B cells that produce large amounts of antibody are called?:

a. Memory B cells

b. Neutrophils

c. T cells

d. Plasma cells

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109) Identity the phagocytic cells that have Toll like Receptor on their membrane:

a. Macrophage

b. Eosinophil

c. Basophil

d. Neutrophil

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110) The following receptor is for T cells?:

a. TCR

b. Scavenger receptor

c. BCR

d. Toll like receptor

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111)

In the complement system, the lytic pathway initiated by the complement :

a. C1qrs

b. MBL

c. C4

d. C5

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112) The following answer is Super antigen:

a. Staphylococus toxin

b. Virus

c. Mycose

d. HIV

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113) The initial complement component that is bound by complement-fixing antibodies is:

a. C5a

b. C1s

c. C3b

d. C1q

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114)

Each of the following is a characteristic of antibodies, EXCEPT :

a. They combine specifically with antigen

b. They are proteins with variable and constant regions

c. They contain carbohydrates

d. They are only secreted by T-cells

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115) The Natural Killer Cells work in the immune system :

a. Kill extracellular antigen

b. Innate immunity

c. Adaptive immunity

d. Adaptive immunity and Innate immunity

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116) The family of Hepatitis B virus is named:

a. Flavivirus

b. Retrovirus

c. Hepadnavirus

d. CMV

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117) The percentage of TH cell among lymphocytes is?:

a. 23%

b. 19%

c. 46%

d. 7%

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118)

The T3 complex of the T-cell receptor:

a. Mediates Immunoglobulin class switching

b. Causes the histamine

c. To transduce a signal to the cell's interior

d. Binds complement

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119) The C5 convertase of Alternative pathway is:

a. C4b2a3b

b. C4b2a4b

c. C4b2b3a

d. C3bBb3b

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120) Which of the following immune cells are effective to destroying intracellular pathogens:

a. T helper cells

b. Antibodies

c. B cells

d. T cytolytic cells

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121) The first immunoglobulin secreted by B cells to make up memory cells is?:

a. IgA

b. IgM

c. IgD

d. IgG

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122)

The following statements are true for Immunoglobins, EXCEPT:

a. All have receptors for complement

b. Possess both variable and constant regions

c. Are antibodies

d. Five major classes IgM, IgG, IgA, IgD, IgE

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123) The function of LGL cell is:

a. Response to bacteria infection

b. Response to antibody

c. Kill pathogen

d. Respose to tumor cells

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124) The following vaccines is not used in United State?:

a. Polio

b. Tuberculsis

c. Varicella

d. Hepatitis A

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125) The natural passive immunity are characterized by?:

a. Placental transfert

b. Kill vaccin Immune cell

c. Immunoglobulins

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126) The following answer is the best marker for Tc cells?:

a. CD4

b. CD8

c. CD21

d. CD3

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127)

All of the following are true with respect to IgG antibodies, EXCEPT:

a. They mediate allergic reaction

b. They are glycoproteins

c. They fix complement

d. They occur on the surface of B lymphocytes

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128)

Superantigens presented to T cells by :

a. Monocyte

b. APC

c. B cell

d. Mast cell

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129)

Which of the following immunoglobulins is present normally in plasma at the highest concentration?:

a. IgE

b. IgG

c. IgA

d. IgM

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130) Which lymphocyte response to HBV infectin?:

a. Th

b. Tc

c. B cells

d. Macrophage

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131) The following activities are belong to the B-cells :

a. Differentiate into plasma cells

b. Antibodies response to antigens

c. Act as antigen-processing cells

d. Receptor antigen monovalent

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132)

The major histocompatibility complex proteins function to:

a. Bind antibody for lymphokine production

b. Degrade T4 and T8 polypeptides

c. Bind antigen for presentation to T-cells

d. Bind complement for cell lysis

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133) These cells can be infected by Mycobacterium tuberculosis:

a. Neutrophil

b. Lymphocyte

c. Eosinophil

d. Macrophage

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134) An antigenic determinant is:

a. Recognized by a epitope

b. A fragment of Antigen

c. Recognized by macrophage

d. Molecule of antigen

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135) The following answers are function of B cell, EXCEPT?:

a. APC

b. Memory B cells

c. Antibody secretion

d. Complement cascade

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136) The following cells are proliferated from myloid progenitor :

a. TH1

b. Dendritic cells

c. Lymphocytes

d. B cells

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137) The following answers is receptor for complement on immunoglobulins:

a. Heavy chain

b. Fc region

c. Fab region

d. Hinge region

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138)

Class of immunoglobulins occurs :

a. Binds complement

b. Causes the histamine release

c. Immunizations, going from IgM to IgG

d. Mediates immunoglobulin class switching

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139) When hepatitis vaccin start to use since year?:

a. 2002

b. 199000%

c. 1960

d. 1985

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140)

Humoral immunity consists of:

a. Pathological cells

b. Cytotoxic cells

c. Normal cells

d. Immunoglobulins

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141) The following statements are true for Antibodies, EXCEPT :

a. Receptors for antigens are monovalent

b. Made of heavy and light chains

c. Fc receptor for complement

d. Extra domain for IgM

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142) Which of the immune cells/molecules are effective to neutralise and opsonse extracellular
pathogens?:

a. Antibodies

b. B cells

c. T cells

d. Complement

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143) Papain cleaves what region of immunoglobulin?:

a. Hinge region

b. Heavy chain and Light chain

c. Heavy chain

d. Light chain

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144) Myeloid cells below lived in tissue:

a. Neutrophil

b. Basophil

c. Lymphocyte

d. Macrophage

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145) Which of the followings are TRUE regarding an Immune response:

a. The T8 support MHC II in cytotoxic reactions

b. The T4 secrete antibody

c. The T4 support MHC class I in helper reactions

d. The T3 complex is signal to the cell's interior to recognize antigen

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146)

The immunoglobulin class which is the least abundant in the normal adult is :

a. IgE

b. IgG

c. IgA

d. IgD

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147)

Which of the following is NOT a structural chain in class I MHC?:

a. α1

b. α2

c. β1

d. β2 –microglobin

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148)

All of the following are true with respect to IgE molecules, EXCEPT :

a. They will cross the placenta and fix complement)

b. They can effect the release of histamine.

c. They are the principal immunoglobulin class involved in allergic reactions.

d. They are involved in mediating anti-parasitic immune responses

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149)

Which of the following is NOT true of interleukins:

a. They are cytokines which can be produced by various cells of the immune system.

b. They are hormones which allow one cell to communicate with another cell.

c. They are in need of receptors on the target cell in order to mediate their effects.

d. They are able to bind antigen with a high level of specificity

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150)

Graft between identical twins is called:

a. Xeno-graft

b. Iso graft

c. Auto graft

d. Allograft

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151) The fragment of Antigen is called:

a. Immunogen

b. Immunoglbulin

c. Hapten

d. Antigenic determinant

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152) The following diseases can be prevented by vaccination?:

a. Hepatitis A and B

b. Hepatitis C and E

c. Hepatitis D and C

d. Hepatitis B and C

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153) The following statement are for Class I MHC proteins, EXCEPT:

a. Participate in T helper function

b. Able to carry an antigen fragment

c. Recognized by the CD8 protein

d. Killed target cells by Tc cells

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154) Which of the following immune cells/molecules are most effective to destroying intracellular
pthogens ?:

a. Plasma cells

b. T cytotoxic cells

c. T helper cells

d. B cells

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155) The Live Attenuated Vaccines are used for the diseases below?:

a. All answers

b. Hepatitis A

c. Varicella zoster

d. Measles

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156)

The disease below can cause allergic reaction:

a. Hepatitis

b. Thalassemia

c. Cancer

d. Asthma

157 / 321

157)

The followings statement are TRUE, EXCEPT :

a. MHC Class II bind antigen and are recognized by the T-cell receptor and the CD4

b. MHC Class 1 bind antigen fragments and are recognized by the Tc-cell receptor

c. MHC Class II carrying antigen presented to cytotoxic T cells

d. MHC Class I generally occur on all cells of the immune system

158 / 321

158)

Individuals unable to make the C4b would be expected to have frequent infections of the :

a. Bacteria

b. Thalassemia

c. Liver disease

d. Diabetis

159 / 321

159)

Which of the following is antiviral:

a. Protein

b. Lysozyme

c. Interferon

d. Hormone

160 / 321

160)

The following statements are true for IgE, EXCEPT:

a. They produce allergic reaction

b. The least immunoglobulin in the plasma

c. Can cross the placental barrier

d. They bind to mast cells

161 / 321

161) The first screening test to detect HBV infection is?:

a. HBsAb

b. HBcAb

c. HBcAg

d. HBsAg

162 / 321

162)

The following statements are true for Antibodies:

a. Are carbohydrates

b. Are made from alpha and beta chains

c. Contain no carbohydrate

d. Contain heavy and light chains

163 / 321

163) Which of the following are mechanisms for neutrophil phagocytosis:

a. Azerophilic granules and defensins

b. defensins

c. Hydrolytic enzymes

d. Azerophilic granules

164 / 321

164)

One principal function of the Class I and Class II major histocompatibility complex is to :

a. Present antigen for recognition by the T-cell receptor

b. Transduce the signal to the T-cell interior

c. Mediate immunoglobulin class

d. Stimulate production of interleukins

165 / 321

165) The function of major histocompatibility complex is:

a. Bind antibody for cytokine secretion

b. Bind epitope for presentation to T-cells

c. Degrade T4 and T8 polypeptides

d. Bind complement for cell lysis

166 / 321

166) The immunoglobulin(s) that have long hinge region are/is:

a. IgG4

b. IgG2

c. IgG3

d. IgG1

167 / 321

167) Which of the following antibody fragments consists of a dimer of the heavy-chain constant
region but lacks the CH1 domains?:

a. Fc

b. F(ab)

c. F(ab)’2

d. Fab

168 / 321

168) The following bonds is responsible for linking of antibody to its chains:

a. Hydrogen bonds

b. Van der Waals forces

c. Hydrophobic forces

d. Disulfide bonds

169 / 321

169) The following organs do not affect by hepatitis virus, EXCEPT:

a. Brain

b. Kidneys

c. Liver

d. Heart

170 / 321

170) The J-chain of immunoglobulin is :

a. Made by T cells

b. Present in IgM

c. Present in IgG

d. Made only by epithelial cells

171 / 321

171) Variable regions of immunoglobulin are:

a. N-terminal of heavy chains

b. Specific recognition of antigen

c. C-terminal of heavy chains

d. Able to fix complement

172 / 321

172)

In acute infection of Hepatitis B, the typical serologic course are:

a. HBcAb

b. HBcAg

c. HBsAg

d. HBsAb

173 / 321

173) Which cells secreted most cytokine in innate immune:

a. T lymphocyte

b. B lymphocyte

c. Plasma cell

d. Macrophage

174 / 321

174) Biological effect of Complement C5a is:

a. Opsonisation

b. Neutrophil activation

c. Inflammation

d. Phagocytosis

175 / 321

175) The much potent anaphylotoxin of the complement is:

a. C3a

b. C5a

c. C2b

d. C4a

176 / 321

176) Which of the following statements about leukocyte function is false?:

a. Neutrophils phagocytose pathogens .

b. Eosinophils release histamine .

c. Leukocytes are cells of the immune response.

d. Eosinophils kill parasites

177 / 321

177) Class II MHC molecule works for?:

a. B cell activation

b. Tc function

c. T helper function

d. An antigen fragment

178 / 321

178) The major function of major histocompatibility complex for antigen intracellular is:

a. Degrade Th and Tc

b. Bind complement for cell lysis

c. Presentation antigen to Th-cells

d. Presentation antigen to Tc-cells

179 / 321

179) The following statements are true for Class I MHC molecules, EXCEPT :

a. Participated in Th function

b. Recognized by the CD8

c. On the APC cells membrane

d. Tc cells kill an infected cells

180 / 321

180)

All of the following are true for IgE molecules, EXCEPT:

a. They involved in allergic reactions.

b. They can cause the release of histamine.

c. They anti-parasitic immune responses.

d. They can fix complement.

181 / 321

181) The variable regions in the heavy chains participate in:

a. Complement receptor

b. Cellular receptor

c. Antigen receptor

d. Cytokine receptor

182 / 321

182) Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Hepatitis B

b. Pertussis

c. Polio

d. Rabies

183 / 321

183) How many percentage of chronic HBV infection can lead to Cirrhosis?:

a. 25%

b. 10%

c. 15%

d. 50%

184 / 321

184) Which lymphocyte are Large Granular Lymphocytes?:

a. T cells

b. B cells

c. NK cells

d. Macropages

185 / 321

185)

The J-chain is :

a. Made only by epithelial cells

b. For immunoglobulin multimer formation

c. Facilitates secretion of pentameric lgM

d. For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

186 / 321

186) Which of the following technic is the best method to detect early infection of hepatitis?:

a. Agglutination

b. RIA

c. ELISA

d. PCR

187 / 321

187)

The function of immune system is to response:

a. Facilitated by T-cells

b. All answers

c. Mediated the humoral and cellular immune system

d. Can be facilitated by antibodies

188 / 321

188)

The following statements are true for Antibodies, EXCEPT:

a. Composed of variable and constant regions

b. They have hypervariable region

c. Non immunogen

d. Made of heavy and light chains

189 / 321

189) These organ is primary lymphoid organ of human?:

a. Tonsil

b. Spleen

c. Thymus

d. Lymph node

190 / 321

190) How many receptors for antigen on the surface of B lymphocyte:

a. 2

b. 1

c. 4

d. 10

191 / 321

191) The incubation period of HBV in the body is?:

a. 30-90 days

b. 45-180 days

c. 30-60 days

d. 60-100 days

192 / 321

192) The chronic HCV infection develop hepatocellular carcinoma in the rate of?:

a. 5%

b. 20%

c. 50%

d. 10%

193 / 321

193) Immunoglobulins do which of the following?:

a. Complement fixation

b. Opsonisation

c. Antigen binding

d. All of the above

194 / 321

194)

The following statement are for adaptive immune response, EXCEPT :

a. Can be facilitated through macrophage cells

b. Can be facilitated by antibodies

c. Is mediated by the humoral and cellular of the immune

d. Can be facilitated through T-cells

195 / 321

195) The basic monomeric Immunoglobulin unit is:

a. Synthesized by a T-cell

b. Four polypeptide chains

c. Four polypeptide chains and One of five major classes

d. One of five major classes

196 / 321

196) Where is the variable region of Immunoglobulin?:

a. CL

b. CH2

c. VL

d. CH3

197 / 321

197) Tumor Necrose Factor (TNF) produce by:

a. Macrophage

b. Macrophage and Tc

c. Neutrophil

d. Tc

198 / 321

198) Which of the following statement is related to IgG physiology in humans?:

a. It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.

b. Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.

c. It is confined to the bloodstream, giving the host protection against blood-borne pathogens.

d. IgG crosses the placental barrier, and thereby provides passive immunity to the fetus.

199 / 321

199) All of the following are true, EXCEPT :

a. An epitope is a fragment of a macromolecule

b. An antigenic determinant is a paratope

c. The variable regions contain the antigen recognition site

d. The class of an immunoglobulin is determined by its heavy chain

200 / 321

200) The factor that stabilize C3 convertase of alternative pathway is :

a. DAF

b. Factor P

c. Factor I

d. Factor H

201 / 321

201)

Histamine is secreted by:

a. Red blood cells

b. White blood cells

c. Epithelial cell

d. Mast cells

202 / 321

202)

T-cell antigen receptors are distinguished from antibodies by which of the following :

a. T-Cell receptors bind various cytokines

b. T-Cell receptors are glycosylated

c. T-Cell receptors bind complement to lyse cells

d. T-cell receptors must interact with antigen

203 / 321

203) The following answers are true for phagocytosis, EXCEPT:

a. Ingest pathogen

b. NK cell

c. Opsonisation

d. Supported by complement

204 / 321

204)

What’s a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:

a. Complement

b. Peptide

c. Antigen

d. MHC II molecule

205 / 321

205)

The function of MHC class II is:

a. Unable to carry antigen fragment

b. Participated in the presentation of Ag

c. Recognized by CD4

d. Recognized by the CD8

206 / 321

206)

All of the following are true about antibodies, EXCEPT:

a. They are a single amino acid sequence

b. They are glycoproteins.

c. They fix complement.

d. They occur on the surface of B-lymphocyte

207 / 321

207)

Which of these cell types can play a primary role in attacking and killing cancer cells?:

a. Platelet

b. Mast cell

c. T cell

d. Cytotoxic

208 / 321

208) The following statement are true for Cytokines, EXCEPT:

a. Control and regulate the immune response

b. Are complement

c. Lymphokines are cytokines

d. Secreted by specialized cells

209 / 321

209)

The following statement is for MHC Class I:

a. Recognized by the CD8 protein

b. Participated in helper function

c. Used to kill by cytotoxic T-cells

d. Not able to carry an antigen fragment

210 / 321

210)

The major role of the complement C3b is to work in conjunction with:

a. MHC for cell recognition

b. Antibodies to lyse cells antgen

c. Antibodies to opsonize cells

d. T-cell for production of lymphokines

211 / 321

211) The following vaccines is used after exposure?:

a. Tetanus

b. Varicella

c. Hypogammaglobulinemia

d. TB

212 / 321

212) The following statements are true for the antigenic determinant :

a. Is paratope

b. Is paratope and Small part of the antigen

c. Small part of the antigen

d. Is the combining site of an antibody

213 / 321

213)

All of the following are true with respect to IgM antibodies, EXCEPT :

a. They are glycoproteins

b. They fix complement

c. They occur on the surface of lymphocytes

d. They mediate allergic reaction

214 / 321

214) The following antigen activate 25% of T cells:

a. Virus

b. HIV

c. Staphylococus toxin

d. Mycose

215 / 321

215) Which cell is Granulocyte:

a. Macrophage

b. Basophil

c. Monocyte

d. Lymphocyte

216 / 321

216) Which kind of cells worked in innate immune system and response to the tumor cells?:

a. Macropages

b. B cells

c. NK cells

d. T cells

217 / 321

217) The following answer is specific for antigen:

a. Hinge region

b. Fc region

c. Heavy chain

d. Fab region

218 / 321

218)

The following statements are true, EXCEPT:

a. IgD provides passive immunity

b. IgA is a secretory immunoglobulin

c. IgM and IgG can fix complement

d. IgE mediates hypersensitivity

219 / 321

219)

All of the following are true of antigen, EXCEPT:

a. They will react with antibodies.

b. They contain epitopes.

c. They contain paratopes

d. They contain antigenic determinants.

220 / 321

220) The component of immune system that can cause fever is :

a. Macrophage

b. Complement

c. Immunoglobulin

d. T lymphocytes

221 / 321

221)

The immunoglobulin Joining chain (J-chain) is:

a. Associated with IgM and IgA

b. Associated with IgM and IgG

c. Produced by mast cells

d. Produced by T-Cells

222 / 321

222)

Complement deficiencies of C3b can cause:

a. Bacterial infection

b. Predisposition to SLE

c. Overproduction of C2b

d. Glucose oxidase deficiency

223 / 321

223) Which of the following components of the adaptive immune system secretes immunoglobulin
(Ig)?:

a. Activated B cell (plasma cell)

b. Resting lymphocytes (B cell, T cell)

c. CD4+ activated T cell

d. CD8+ cytotoxic T cell (CTL)

224 / 321

224) The average incubation period of Hepatitis A is?:

a. 15 days

b. 60 days

c. 30 days

d. 7 days

225 / 321

225) The following characcteristic is common for T and b cells?:

a. Polypeptide chains

b. Recognize antigen

c. able to fix complement

d. have constant regions

226 / 321

226)

The component of immune system that can cause inflammation is :

a. T lymphocytes

b. Immunoglobulin

c. Macrophage

d. Complement

227 / 321

227)

All of the following are true, EXCEPT:

a. IgG antibody is pentavalent

b. The variable contain the antigen recognition site

c. IgM antibody is pentamer

d. An epitope is a portion of an antigen

228 / 321

228) The following statement are MOST closely related to each, EXCEPT:

a. Epitope

b. Antigen

c. Allergen

d. Antibody

229 / 321

229) Intracellular pathogen is presented to the Tc by:

a. MHC II

b. MHC I

c. Lymphocytes

d. TH

230 / 321

230)

Individuals make up over C4a would be expected to have:

a. Bacteria

b. Liver disease

c. Diabetis

d. Anaphylaxia

231 / 321

231) The following answer is the function of IgM, EXCEPT :

a. Cross placenta

b. Activate complement

c. Primary response to antigen

d. Opsonize bacteries

232 / 321

232) HBV infection is characterized by the present of ?:

a. HBeAg

b. HBcAg

c. All answers

d. HBsAg

233 / 321

233)

The followings statement are TRUE, EXCEPT:

a. MHC II bind antigen and recognized by the Th

b. MHC II carrying antigen presented to Tc

c. MHC I presented on all cells of the immune

d. MHC I bind antigen and recognized by the Tc

234 / 321

234) The lectin pathway of the complement is initiated by:

a. Factor B

b. C1qrs

c. MBL

d. C3

235 / 321

235)

Immediate hypersensitivity reactions are below, EXCEPT:

a. The consequence of antigen-antibody reactions

b. If the antigen is an allergen

c. Result from histamine release

d. Phagocytosis

236 / 321

236) The following disease is the cancer of lymphocyte?:

a. Listeria

b. Lymphocytopenia

c. Mycobacterium

d. Non-Hodgkin lymphoma

237 / 321

237) In chronic infection of hepatitis B, the antibody persists in the whole life is?:

a. HBsAg

b. HBcAb

c. HBsAb

d. HBcAg

238 / 321

238)

In the alternative pathway of the complement system, the factors below are useful to prevent the generation of C3 convertase :

a. Factor P

b. Factor F

c. C1-INH

d. C3-BP

239 / 321

239)

The functional activity of the T-cell:

a. Is related with CD4 or CD8 associated polypeptides, Occurs after recognition of an epitope, Can be mediated through cytokines

b. Can be mediated through cytokines

c. Occurs after recognition of an epitope

d. Is related with CD4 or CD8 associated polypeptides

240 / 321

240) Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis D virus

b. Hepatitis B virus

c. Hepatitis C virus

d. Hepatitis A virus

241 / 321

241)

In the complement system, the classic pathway initiates by the complement :

a. C5

b. MBL

c. C4

d. C1qrs

242 / 321

242) The vaccine prepared from living and inactivated microbe is considered as?:

a. A toxoid

b. Antibody

c. Denatured

d. Atenuated vaccin

243 / 321

243)

What distinguishes helper T-cells from cytotoxic T-cells :

a. Cytotoxic cells recognize antigen complexed with MHC class I molecules

b. Helper cells recognize antigen complexed with MHC class I molecules

c. Cytotoxic cells recognize antigen complexed with MHC class I molecules and. Helper cells recognize antigen complexed with MHC class II molecules

d. Helper cells recognize antigen complexed with MHC class II molecules

244 / 321

244)

What distinguishes helper T-cells from cytotoxic T-cells:

a. Th recognize antigen with MHC II

b. Tc recognize antigen with MHC I and Th recognize antigen with MHC II

c. Th recognize antigen with MHC I

d. Tc recognize antigen with MHC I

245 / 321

245) The variable regions in the light chains participate in:

a. Affinity of the complement receptors.

b. Interaction of the Fab with cytokines.

c. Fc receptor binding.

d. Epitope binding.

246 / 321

246)

Skin is a________ barrier:

a. Phagocytic

b. Inflammatory

c. Physiological

d. Anatomical

247 / 321

247)

Which cell is directly secreted immunoglobulin:

a. Macrophage

b. Plasma cell

c. T lymphocyte

d. B lymphocyte

248 / 321

248) Which type of antibody is not effective in activating complement?:

a. IgG1

b. IgG4

c. IgG3

d. IgG2

249 / 321

249)

Clinical abnormalities of the Immune system can result from the following statement, EXCEPT:

a. Abnormal lymphocyte proliferation

b. T cells proliferation

c. HIV Infection

d. Deficiency diseases

250 / 321

250) B Cells are activated by?:

a. Antigen

b. Interferon

c. Memory cells

d. Antibody

251 / 321

251)

One principal function of the Class I and Class II major histocompatibility complex is to:

a. Mediate immunoglobulin class

b. Help T cell for the recognition Antigen

c. Transduce the signal to the T-cell interior

d. Stimulate production of interleukins

252 / 321

252) T cells secreted cytokine to activate cells in blood vessel, This phenomen is called:

a. All answers

b. Paracrine

c. Autocine

d. Endocrine

253 / 321

253) The following vaccines is Microbial Fragment Vaccines?:

a. Clostridium tetani

b. Varicella

c. Polio

d. Hepatitis A

254 / 321

254)

One principal function of complement is to:

a. Phagocytize antigens

b. Mediate the release of histamine

c. Bind antibodies attached to cell surfaces and to lyse these cells

d. Inactivate perforins

255 / 321

255) Which properties do the T-cell receptor and the antibody share in common:

a. Both are polypeptide chains

b. Both have constant regions

c. Both recognize antigen fragments

d. Both are able to fix complement

256 / 321

256) The following cells of immune system cam make IgE:

a. Monocytes

b. Mast cells

c. Eosinophils

d. Mast cells and Eosinophils

257 / 321

257)

What is the term used to describe white blood cells migrating toward bacteria? :

a. Phagocytosis

b. Phototaxis

c. Chemotaxis

d. Zeiosis

258 / 321

258)

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgE

b. IgG

c. IgM

d. IgA

259 / 321

259) The following activity is indicated T cell cytotoxic:

a. Epitope presented to CD4

b. MHC-II restricted

c. MHC-I restricted

d. B cell activation

260 / 321

260)

The Biological Effects of C3b is :

a. Susceptibility to bacterial infections

b. Lack of opsonisation

c. Phagocyte activation

d. Anaphylaxia

261 / 321

261) Which of the following are true statements:

a. IgD provides immunization

b. IgE lyses allergen

c. IgM and IgG can fix complement

d. IgA can fix complement

262 / 321

262) Which of the following statements about HBV is NOT correct?:

a. RNA virus

b. Hepato carcinoma

c. Parenteral route

d. Can replicate

263 / 321

263) The following viral hepatitis are chronic hepatitis, EXCEPT?:

a. Hepatitis A

b. Heepatitis C

c. Hepatitis B

d. Hepatitis D

264 / 321

264) All of these tests show that patient has been vaccinationated against HBV, EXCEPT?:

a. HBsAg negative

b. HBcAb Negative

c. IgM positive

d. HBsAb positive

265 / 321

265)

Which cells are proliferated from myeloid progenitor:

a. TH1

b. Lymphocytes

c. B cells

d. Dendritic cells

266 / 321

266) The function of T cytotoxic lymphocyte is?:

a. Lyse pathogen

b. Lyse target cell

c. Lyse paasite

d. Lyse bacterie

267 / 321

267) The rabic vaccin is used to?:

a. Cure tetanus infection

b. Cure rabie infection

c. Prevent tetanus infection

d. Prevent rabie infection

268 / 321

268) The first sign of infection is the characteristic appearance of ?:

a. HBcAb

b. HBsAg

c. HBeAg

d. HBsAb

269 / 321

269) The function of Class III MHC proteins are :

a. Transport complement protein

b. Recognized antigen by CD8

c. Recognized antigen by CD4

d. Lyse antigen

270 / 321

270) The cancer of T cells are called?:

a. Hodgkin lymphoma

b. Extranodal T cell lymphoma

c. All answers

d. Non-Hodgkin lymphoma

271 / 321

271) These blood cells have memory after pathogens infection, EXCEPT? TH cells?:

a. Macrophages

b. B cells

c. Tc cells

272 / 321

272) Immunity acquired after an infection is?:

a. Innate immunity

b. Passive immunity

c. Active immunity

d. Response immunity

273 / 321

273) The tetanus vaccine is prepare from ?:

a. Toxin antigen

b. Killed antigen

c. Inactivated antigen

d. Virulence antigen

274 / 321

274) The following immunoglobulin is used to produe vaccine?:

a. IgG4

b. IgM

c. IgA

d. IgG

275 / 321

275) How many serotypes of HCV in the world?:

a. Many

b. 2

c. 4

d. 6

276 / 321

276) The following immunoglobulin(s) become monomer when they attaché antigen :

a. IgA

b. IgG

c. IgM

d. IgE

277 / 321

277) The following molecules can activate B cells to secrete antibody, EXCEPT:

a. Allergen

b. Antigen

c. Hapten

d. Antigenic determinant

278 / 321

278) Class II MHC proteins are:

a. Participate in T helper function

b. Not able to carry an epitope

c. Used to kill cytotoxic T-cells

d. Recognized by the CD8 protein

279 / 321

279) Biological effect of Complement C2b is:

a. Anaphylaxis

b. Edema

c. Opsonisation

d. Phagocytosis

280 / 321

280) The following tests show that patient got chronic infection of HCV?:

a. Anti-HCV positive

b. IgM positive

c. ALT elevated

d. ALT elevated and Anti-HCV positive

281 / 321

281) The function of MHC class II is:

a. Unable to carry antigen fragment

b. Recognized by CD4

c. Presentation Ag to Th cell

d. Recognized by the CD8

282 / 321

282) Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgG

b. IgA

c. IgE:

d. IgM

283 / 321

283)

Which among the following is anti-bacterial ?:

a. Hormone

b. Lysozyme

c. Protein

d. Interferon

284 / 321

284)

The followings statement are TRUE for Target cell lysis and destruction,EXCEPT :

a. Perforin released from antigen-specific cytotoxic T-cells

b. Complement binding to IgE antibodies which have bound to epitopes on the cell surface

c. Complement binding to IgG and IgM which have bound to epitopes on the target cell

d. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

285 / 321

285) The disease below can cause by autoimmune:

a. Hepatitis

b. Thalassemia

c. Cancer

d. SLE

286 / 321

286) Regulatory T cells (Treg cells), formerly known as ?:

a. Natural T reg

b. CD4+ T reg

c. Suppressor T cells

d. Adaptive T reg

287 / 321

287) Light chains are :

a. Specific for each class of antibody

b. Complement fixation

c. Have only a constant region

d. Reactive with antigen

288 / 321

288) The tests below show that patient has an chronic infection of HBV?:

a. All answers

b. HBsAg positive

c. HBcAb positive

d. HBsAb negative

289 / 321

289) The Complement that produce anaphylactic much more potent is:

a. C3a

b. C5a

c. C4a

d. C2b

290 / 321

290)

The major role of the complement system is to work in conjunction with:

a. T-cell receptor for production of lymphokines

b. MHC for cell recognition

c. Antibodies to lyse cells via the C8 and C9 components

d. Antibodies to opsonize cells

291 / 321

291) The Natural Killer T Cells work in the immune system :

a. Innate immunity

b. Adaptive immunity and Innate immunity

c. Adaptive immunity

d. Link between Adaptive and Innate immune

292 / 321

292) The following statement is true for helper T-cells :

a. Helper cells recognize antigen with MHC class II

b. Helper cells recognize antigen with MHC class I and II

c. Cytotoxic cells recognize antigen with MHC class II

d. Helper cells recognize antigen with MHC class I

293 / 321

293)

The T3 complex of the T-cell receptor :

a. Mediates Immunoglobulin class switching

b. Binds complement

c. Causes the histamine

d. To transduce a signal to the cell's interior binding to antigen

294 / 321

294) The following statement are for Target cell lysis and destruction, EXCEPT:

a. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

b. Complement binding to IgG and IgM which have bound to epitopes on the target cell

c. Perforin released from antigen-specific cytotoxic T-cells

d. Complement binding to IgE which have bound to epitopes on the cell surface

295 / 321

295)

Which immunoglobulin is the principal one that is unkown function:

a. IgD

b. IgM

c. IgG

d. IgA

296 / 321

296) The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBcAb

b. HBsAb

c. HBsAg

d. HBcAg

297 / 321

297) The tests below show that patient is already vaccinated against HBV?:

a. All answers

b. HBsAb positive

c. HBcAb negative

d. HBsAg negative

298 / 321

298) Which of the following components of the innate immune system involves the release of
histamine?:

a. Eosinophil

b. Tissue mast cell

c. Macrophage

d. Neutrophil

299 / 321

299) Which of the following is a β structural chain in class I MHC?:

a. β2 –microglobin

b. α1

c. α2

d. β1

300 / 321

300)

The followings statement are FALSE for Target cell lysis and destruction :

a. C3b fix to IgE which have epitopes

b. Perforin released from Tc

c. C3b fix to IgG and IgM which have epitopes

d. Tc recognizing specific epitopes

301 / 321

301) Which cell is Monocyte:

a. CD8

b. CD4

c. CD15

d. CD14

302 / 321

302) Which type of cell destroys body cells that cause by infection?:

a. Cytotoxic T cells

b. Memory B cells

c. Memory T cells

d. Plasma B cells

303 / 321

303)

Which of the following causes AIDS ?:

a. TMV

b. Fungus

c. Retrovirus

d. Bacteria

304 / 321

304)

Clinical abnormalities of the Immune system can result from the activities below, EXCEPT:

a. Abnormal lymphocyte proliferation

b. HIV Infection

c. T cell secrete cytokine

d. Bacterial infection

305 / 321

305) Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:

a. Neisseria meningitides

b. Haemophilus influenzae B

c. Hepatitis B virus

d. Polio

306 / 321

306) Which antigen is direct presented to B cell?:

a. Self- antigen

b. T- Independent antigen

c. T- dependent antigen

d. Non self- antigen

307 / 321

307) Which of the following immunoglobulin is first synthesized in an immune system to response
an pathogen?:

a. IgG

b. IgE

c. IgA

d. IgM

308 / 321

308) The most infection chronic and acute HBV is in?:

a. Adult

b. Female

c. Male

d. Children

309 / 321

309) Class II MHC proteins are :

a. Used to participate in helper function

b. Recognized by CD4

c. Recognized by CD8

d. Recognized by CD4 and Used to participate in helper function

310 / 321

310) The specific type of functional activity of a T-cell following antigen recognition is determined
by:

a. Antigen receptor

b. MHC class II presenting the antigen fragment

c. carbohydrate side chains

d. CD4 or CD8 can bind antigens

311 / 321

311) The answers below are characteristic of antigen, EXCEPT:

a. Contain epitopes

b. Contain paratopes

c. React with antibody

d. Are toxin

312 / 321

312) Which type of antibody is MOST effective in activating complement?:

a. IgM

b. IgG1

c. IgG3

d. IgG2

313 / 321

313)

In the alternative pathway of the complement system, the factors below are useful to stabilise the generation of C3 convertase :

a. C3-BP

b. C1-INH

c. Factor P

d. Factor F

314 / 321

314) The cells that have azerophilic granule to facilitate phagocytosis is:

a. Neutrophils

b. Basophils

c. Monocytes

d. Mast cells

315 / 321

315) Which of the following bacteriocidal mechanisms is oxygen dependant?:

a. NADPH oxidation

b. Lactoferrin

c. Hydrolytic enzymes

d. Defensins

316 / 321

316) The primairy response of antibody to the HBV is?:

a. IgG

b. IgE

c. IgM

d. IgA

317 / 321

317) The TH cells produced cytokines to response the viral infection?:

a. Tumor necrose factor

b. IL-2

c. Interferon

d. Chimokine

318 / 321

318) These cytokines secreted by T helper cell?:

a. TNF-α

b. IL-2

c. Chimokine

d. Interferon

319 / 321

319) The azerophilic granule used to facilitate phagocytosis:

a. Virus

b. Parasite

c. Mycose

d. Bacteria

320 / 321

320) Which immunoglobulin is used to test for blood group:

a. IgA

b. IgE

c. IgM

d. IgG

321 / 321

321) The two types of lymphocytes are ?:

a. T and B cells

b. Erythrocyte and T cells

c. Platelet and Erythrocyte

d. Platelet and B cells

Your score is

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និស្សិតអាចប្រាប់មកកាន់ពួកយើងបានដើម្បីកែកំហុស ឬអំពីបញ្ហាដោយអចេតនាណាមួយដែលកើតមានកំឡុងពេលធ្វើតេស្ត