Immunology Preparation (Pr. Kiet Vannseth)

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1) Which type of cell destroys body cells that cause by infection?:

a. Cytotoxic T cells

b. Memory B cells

c. Plasma B cells

d. Memory T cells

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2) All of these tests show that patient has been infected with HBV, EXCEPT?:

a. HBsAb positive

b. HBsAg negative

c. HBcAb positive

d. HBcAg positive

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3) The following disease is the cancer of lymphocyte?:

a. Non-Hodgkin lymphoma

b. Lymphocytopenia

c. Listeria

d. Mycobacterium

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The followings statement are TRUE, EXCEPT :

a. MHC Class II carrying antigen presented to cytotoxic T cells

b. MHC Class I generally occur on all cells of the immune system

c. MHC Class 1 bind antigen fragments and are recognized by the Tc-cell receptor

d. MHC Class II bind antigen and are recognized by the T-cell receptor and the CD4

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5) B and T cells are produced by stem cells located in:?:

a. Bone marrow

b. Spleen

c. Circulatery system

d. Liver

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6) The following receptor is for T cells?:

a. TCR

b. Scavenger receptor

c. BCR

d. Toll like receptor

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7) The C5 convertase of Alternative pathway is:

a. C4b2a3b

b. C3bBb3b

c. C4b2a4b

d. C4b2b3a

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Which of the following immunoglobulins is present normally in plasma at the highest concentration?:

a. IgE

b. IgM

c. IgA

d. IgG

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9) The following vaccines is Microbial Fragment Vaccines?:

a. Polio

b. Varicella

c. Clostridium tetani

d. Hepatitis A

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10) The function of MHC class II is:

a. Recognized by the CD8

b. Unable to carry antigen fragment

c. Recognized by CD4

d. Presentation Ag to Th cell

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11) The most infection chronic and acute HBV is in?:

a. Adult

b. Male

c. Female

d. Children

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12)

The following statements are true, EXCEPT:

a. IgE mediates hypersensitivity

b. IgD provides passive immunity

c. IgA is a secretory immunoglobulin

d. IgM and IgG can fix complement

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13)

Thymus growth occurs up to:

a. 5 years

b. 17 years

c. 12 years

d. 30 years

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14) The disease below can cause by autoimmune:

a. SLE

b. Cancer

c. Thalassemia

d. Hepatitis

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15) The natural passive immunity are characterized by?:

a. Placental transfert

b. Kill vaccin Immune cell

c. Immunoglobulins

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16) The function of LGL cell is:

a. Respose to tumor cells

b. Response to bacteria infection

c. Response to antibody

d. Kill pathogen

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17) The tests below show that patient is susceptible to an HBV infection?:

a. HBsAb negative

b. HBcAb negative

c. All answers

d. HBsAg negative

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18) The function of Class III MHC proteins are :

a. Recognized antigen by CD4

b. Lyse antigen

c. Recognized antigen by CD8

d. Transport complement protein

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19) All of the following are the type RNA virus, EXCEPT?:

a. Hepatitis A

b. Hepatitis B

c. Hepatitis C

d. Hepatitis E

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20)

The function of MHC class II is:

a. Participated in the presentation of Ag

b. Unable to carry antigen fragment

c. Recognized by CD4

d. Recognized by the CD8

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21)

The following statements are not true for Immunoglobins

a. All have receptors for complement

b. Five major classes of immunoglobulin

c. Possess both variable and constant regions

d. They have Fab

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22) The function of antibody produced by B cells are?:

a. Complement fixation

b. Opsonisation

c. All answers

d. Neutralisation

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23) An antigenic determinant is:

a. Recognized by macrophage

b. Recognized by a epitope

c. A fragment of Antigen

d. Molecule of antigen

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24) The following vaccines are Live Attenuated Vaccines, EXCEPT?:

a. Tetanus

b. Varicella

c. Hepatitis A

d. Polio

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25) The function of major histocompatibility complex for antigen in the cytosol is:

a. Presentation antigen to Th-cells

b. Transport protein

c. Presentation antigen to Tc-cells

d. Bind complement for cell lysis

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26)

Humoral immunity consists of:

a. Cytotoxic cells

b. Normal cells

c. Immunoglobulins

d. Pathological cells

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27) The following statement are function of immune system, EXCEPT:

a. Mediated the humoral and cellular response

b. Allow pathogen to infect the bod

c. Can be facilitated by antibodies

d. Facilitated by T-cells

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28) Class II MHC proteins are :

a. Recognized by CD8

b. Recognized by CD4 and Used to participate in helper function

c. Used to participate in helper function

d. Recognized by CD4

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29) The following antigen activate 25% of T cells:

a. Virus

b. Staphylococus toxin

c. HIV

d. Mycose

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30) How many serotypes of HCV in the world?:

a. 4

b. 2

c. Many

d. 6

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31) The CD marker of B cells are?:

a. CD19 and CD21

b. CD16 and CD56

c. CD3 and CD54

d. CD3 and CD8

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32)

The major histocompatibility complex proteins function to:

a. Bind antibody for lymphokine production

b. Bind antigen for presentation to T-cells

c. Bind complement for cell lysis

d. Degrade T4 and T8 polypeptides

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33) The rabic vaccin is used to?:

a. Prevent rabie infection

b. Cure tetanus infection

c. Prevent tetanus infection

d. Cure rabie infection

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34) The following statements are true for Antibodies, EXCEPT :

a. Extra domain for IgM

b. Fc receptor for complement

c. Receptors for antigens are monovalent

d. Made of heavy and light chains

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35) The following vaccines is not used in United State?:

a. Polio

b. Tuberculsis

c. Varicella

d. Hepatitis A

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36)

Which immunoglobulin is the principal one found in secretions such as mucus :

a. IgD

b. IgA

c. IgM

d. IgG

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37)

All of the following are true with respect to IgG antibodies, EXCEPT:

a. They occur on the surface of B lymphocytes

b. They are glycoproteins

c. They mediate allergic reaction

d. They fix complement

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38)

The T3 complex of the T-cell receptor:

a. Causes the histamine

b. Mediates Immunoglobulin class switching

c. To transduce a signal to the cell's interior

d. Binds complement

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39) B Cells are activated by?:

a. Antigen

b. Memory cells

c. Antibody

d. Interferon

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40) Which antigen is direct presented to B cell?:

a. Non self- antigen

b. Self- antigen

c. T- dependent antigen

d. T- Independent antigen

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41)

All of the following are true about antibodies, EXCEPT:

a. They are glycoproteins.

b. They are a single amino acid sequence

c. They occur on the surface of B-lymphocyte

d. They fix complement.

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42)

All of the following are true for IgE molecules, EXCEPT:

a. They can cause the release of histamine.

b. They anti-parasitic immune responses.

c. They involved in allergic reactions.

d. They can fix complement.

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43)

All of the following are true, EXCEPT:

a. IgG antibody is bivalent

b. The variable contain the antigen recognition site

c. An epitope is a portion of an antigen

d. IgM antibody is pentavalent

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44) The following answers is receptor for complement on immunoglobulins:

a. Fab region

b. Hinge region

c. Heavy chain

d. Fc region

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45) Which of the following immune cells/molecules are most effective to destroying intracellular
pthogens ?:

a. Plasma cells

b. B cells

c. T helper cells

d. T cytotoxic cells

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46) The class of an immunoglobulin is determined by:

a. Class I and II MHC

b. The light chain

c. The antigen

d. The heavy chain

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47)

The J-chain is :

a. Made only by epithelial cells

b. Facilitates secretion of pentameric lgM

c. For immunoglobulin multimer formation

d. For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

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48)

Individuals make up over C4a would be expected to have:

a. Anaphylaxia

b. Bacteria

c. Diabetis

d. Liver disease

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49) The percentage of TH cell among lymphocytes is?:

a. 7%

b. 46%

c. 23%

d. 19%

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50)

Skin is a________ barrier:

a. Inflammatory

b. Phagocytic

c. Physiological

d. Anatomical

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51) The classical pathway of the complement is initiated by:

a. C3

b. MBL

c. C1qrs

d. Factor B

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52) All of the following are a part of innate immune respond, EXCEPT :

a. Pathways of complement activation

b. Macrophage secrete cytokines

c. Natural Killer cells

d. T cells secrete antibody

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53) Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis G virus

b. Hepatitis A virus

c. Hepatitis E virus

d. Hepatitis B virus

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54) The following statement is the basic monomeric immunoglobulin unit, EXCEPT:

a. Same protein type for all antibody classes

b. Composed of glycoproptein chains

c. The receptor is TCR

d. Able to associate with J- chain to form multimers

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55) Where is the variable region of Immunoglobulin?:

a. CH2

b. CL

c. VL

d. CH3

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56) The following immunoglobulin is used to produe vaccine?:

a. IgA

b. IgG4

c. IgG

d. IgM

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57) Lymphocytes that develop immunocompetence in the thymus are?:

a. B cells

b. T cells

c. LGL's

d. NK cells

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58) The specific type of functional activity of a T-cell following antigen recognition is determined
by:

a. carbohydrate side chains

b. Antigen receptor

c. CD4 or CD8 can bind antigens

d. MHC class II presenting the antigen fragment

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59) The following bonds is responsible for linking of antibody to its chains:

a. Disulfide bonds

b. Van der Waals forces

c. Hydrophobic forces

d. Hydrogen bonds

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60) How many percentage of chronic HBV infection can lead to Cirrhosis?:

a. 25%

b. 50%

c. 15%

d. 10%

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61) The factor that stabilize C3 convertase of alternative pathway is :

a. Factor P

b. Factor I

c. Factor H

d. DAF

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62) The cancer of T cells are called?:

a. Hodgkin lymphoma

b. All answers

c. Non-Hodgkin lymphoma

d. Extranodal T cell lymphoma

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63) The fragment of Antigen is called:

a. Hapten

b. Antigenic determinant

c. Immunoglbulin

d. Immunogen

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64)

Which among the following is anti-bacterial ?:

a. Hormone

b. Protein

c. Interferon

d. Lysozyme

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65) How many receptors for antigen on the surface of B lymphocyte:

a. 10

b. 4

c. 1

d. 2

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66) The following answer is Super antigen:

a. Staphylococus toxin

b. Virus

c. HIV

d. Mycose

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67)

The following statements are true for Antibodies:

a. Contain no carbohydrate

b. Contain heavy and light chains

c. Are carbohydrates

d. Are made from alpha and beta chains

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68)

Histamine is secreted by:

a. Red blood cells

b. White blood cells

c. Mast cells

d. Epithelial cell

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69) The J-chain of immunoglobulin is :

a. Present in IgG

b. Made by T cells

c. Present in IgM

d. Made only by epithelial cells

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70) The first antibody secreted by B cells during infection is?:

a. IgM

b. IgE IgA

c. IgG

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71) The following molecules can activate B cells to secrete antibody, EXCEPT:

a. Hapten

b. Antigenic determinant

c. Allergen

d. Antigen

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72) The screening test for HBV infection is?:

a. HBcAg

b. HBsAb

c. HBcAb

d. HBsAg

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73)

The T3 complex of the T-cell receptor :

a. Causes the histamine

b. Binds complement

c. To transduce a signal to the cell's interior binding to antigen

d. Mediates Immunoglobulin class switching

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74)

What’s a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:

a. MHC II molecule

b. Peptide

c. Antigen

d. Complement

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75) Myeloid cells below lived in tissue:

a. Lymphocyte

b. Macrophage

c. Neutrophil

d. Basophil

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76)

The followings statement are TRUE for Target cell lysis and destruction,EXCEPT :

a. Complement binding to IgG and IgM which have bound to epitopes on the target cell

b. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

c. Perforin released from antigen-specific cytotoxic T-cells

d. Complement binding to IgE antibodies which have bound to epitopes on the cell surface

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77) Which of the following components of the innate immune system involves the release of
histamine?:

a. Tissue mast cell

b. Neutrophil

c. Macrophage

d. Eosinophil

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78) The immunoglobulin(s) that have long hinge region are/is:

a. IgG1

b. IgG2

c. IgG3

d. IgG4

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79) All of the following are true, EXCEPT :

a. An epitope is a fragment of a macromolecule

b. The variable regions contain the antigen recognition site

c. The class of an immunoglobulin is determined by its heavy chain

d. An antigenic determinant is a paratope

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80) Cell mediated immunity in adaptive immune is carried out by?:

a. B cells

b. Antibody

c. T cells

d. Antigen

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81)

The function of immune system is to response:

a. Mediated the humoral and cellular immune system

b. Facilitated by T-cells

c. Can be facilitated by antibodies

d. All answers

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82) In a chronic infection of Hepatitis B, the typical serologic course are :

a. HBsAb

b. HBsAg and HBcAb

c. HBcAb

d. HBsAg

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83) Biological effect of Complement C3a is:

a. Edema

b. Opsonisation

c. Anaphylaxis

d. Phagocytosis

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84)

Hyper variability regions are present in:

a. Dark chain

b. Heavy and light

c. Light chain only

d. Heavy chain only

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85)

Complements are chemically:

a. Proteins

b. Glycogens

c. Glycoproteins

d. Lipoproteins

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86) Which type of antibody is not effective in activating complement?:

a. IgG3

b. IgG2

c. IgG4

d. IgG1

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87) Which of the following is NOT a major feature (characteristic) of the adaptive immune
system?:

a. Diversity

b. Specificity

c. Improvement

d. Memory

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88) The following activity is indicated T cell cytotoxic:

a. B cell activation

b. Epitope presented to CD4

c. MHC-II restricted

d. MHC-I restricted

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89)

The immunoglobulin class which is the least abundant in the normal adult is :

a. IgG

b. IgA

c. IgD

d. IgE

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90) HBV infection is characterized by the present of ?:

a. HBeAg

b. HBcAg

c. HBsAg

d. All answers

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91) The region of immunoglobulin term: Binds to various cellular receptors and to complement:

a. Light chain

b. Heavy chain

c. Fab region

d. Fc region

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92) Intracellular pathogen is presented to the Tc by:

a. MHC II

b. MHC I

c. TH

d. Lymphocytes

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93) Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:

a. Neisseria meningitides

b. Haemophilus influenzae B

c. Hepatitis B virus

d. Polio

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94) The following diseases can be prevented by vaccination?:

a. Hepatitis C and E

b. Hepatitis A and B

c. Hepatitis D and C

d. Hepatitis B and C

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95)

What distinguishes helper T-cells from cytotoxic T-cells:

a. Tc recognize antigen with MHC I

b. Tc recognize antigen with MHC I and Th recognize antigen with MHC II

c. Th recognize antigen with MHC I

d. Th recognize antigen with MHC II

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96) Which of the following organ is primarily infected by Hepatitis viruses?:

a. Spleen

b. Lung

c. Intestines

d. Liver

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97) Which properties do the T-cell receptor and the antibody share in common:

a. Both recognize antigen fragments

b. Both are polypeptide chains

c. Both are able to fix complement

d. Both have constant regions

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98)

All of the following are true with respect to IgE molecules, EXCEPT :

a. They will cross the placenta and fix complement)

b. They can effect the release of histamine.

c. They are the principal immunoglobulin class involved in allergic reactions.

d. They are involved in mediating anti-parasitic immune responses

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99) Which of the following are mechanisms for neutrophil phagocytosis:

a. defensins

b. Azerophilic granules and defensins

c. Azerophilic granules

d. Hydrolytic enzymes

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100) T cells secreted cytokine to activate T cells neighbering, This phenomen is called?:

a. None about

b. Autocrine

c. Paracrine

d. Endocrine

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101) These cells can be infected by Mycobacterium tuberculosis:

a. Macrophage

b. Lymphocyte

c. Neutrophil

d. Eosinophil

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102) The following activities are belong to the B-cells :

a. Act as antigen-processing cells

b. Receptor antigen monovalent

c. Differentiate into plasma cells

d. Antibodies response to antigens

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103) Tumor Necrose Factor (TNF) produce by:

a. Tc

b. Neutrophil

c. Macrophage

d. Macrophage and Tc

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104)

In the alternative pathway of the complement system, the factors below are useful to stabilise the generation of C3 convertase :

a. C1-INH

b. C3-BP

c. Factor F

d. Factor P

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105)

The type of an immunoglobulin is determined by:

a. The carbohydrate

b. The light chain

c. The variable region

d. The heavy chain

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106) The Immunoglobulins are secreted by:

a. Macrophages

b. Plasma cells

c. T-cells

d. B-cells

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107) The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBcAg

b. HBsAb

c. HBsAg

d. HBcAb

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108) Clinical abnormalities of the Immune system can result from the activities below:

a. Neutrophils kill bacteria

b. Abnormal lymphocyte proliferation

c. Plasma cells secrete antibody

d. T cell secrete cytokine

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109) Which immunoglobulin is used to produce vaccine:

a. IgA

b. IgE

c. IgG

d. IgM

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110) The chronic HCV infection develop hepatocellular carcinoma in the rate of?:

a. 10%

b. 5%

c. 20%

d. 50%

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111) The following statements are true for Class II MHC molecules, EXCEPT :

a. Presented antigen to Tc cells

b. Used to participate in Th function

c. Able to carry an antigen fragment

d. Recognized by the CD4

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112) Pepsin cleaves what region of immunoglobulin?:

a. Hinge region

b. Heavy chain

c. Heavy chain and Light chain

d. Light chain

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113) The receptor BCR for an antigen on the membrane of B cell is?:

a. Trivalent

b. Monovalent

c. Bivalent

d. None about

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114) The percentage of lymphocytes leave the thymus to become mature immunocompetent T
cells is?:

a. 98%

b. 10%

c. 90%

d. 2%

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115)

Complement deficiencies of C3b can cause:

a. Predisposition to SLE

b. Bacterial infection

c. Overproduction of C2b

d. Glucose oxidase deficiency

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116)

The component of immune system that can cause inflammation is :

a. Complement

b. Immunoglobulin

c. Macrophage

d. T lymphocytes

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117)

Which cells are proliferated from myeloid progenitor:

a. Lymphocytes

b. TH1

c. Dendritic cells

d. B cells

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118) Which of the following is a β structural chain in class I MHC?:

a. α1

b. α2

c. β1

d. β2 –microglobin

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119)

Class II MHC are :

a. Recognized by the CD4 protein

b. Used to kill by cytotoxic T-cells

c. Used to participate in cytotoxic function

d. Not able to carry an antigen fragment

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120) Biological properties of C5a are:

a. Attract and activate PMN

b. Anaphylactic much potent

c. All answers

d. Chimotactic activity

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121) Which lymphocyte are Large Granular Lymphocytes?:

a. Macropages

b. NK cells

c. B cells

d. T cells

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122) T- independent antigen presented to the following lymphocyte?:

a. Tc cells

b. B cells

c. TH cells

d. TH1 cell

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123)

The following statement are for adaptive immune response, EXCEPT :

a. Can be facilitated by antibodies

b. Can be facilitated through macrophage cells

c. Can be facilitated through T-cells

d. Is mediated by the humoral and cellular of the immune

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124) Molecule binding to their receptors at high affinity :

a. All answer

b. Cytokines

c. Antigen

d. Antibody

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125) The primairy response of antibody to the HBV is?:

a. IgE

b. IgA

c. IgG

d. IgM

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126) The basic monomeric Immunoglobulin unit is:

a. Four polypeptide chains and One of five major classes

b. Four polypeptide chains

c. One of five major classes

d. Synthesized by a T-cell

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127)

The following statements are true for Antibodies

a. Are carbohydrates

b. Contain cytoplasmic region

c. Are made from alpha and beta chains

d. Have variable region

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128) The following vaccines is used after exposure?:

a. Varicella

b. Tetanus

c. Hypogammaglobulinemia

d. TB

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129) Class II MHC molecule works for?:

a. An antigen fragment

b. Tc function

c. T helper function

d. B cell activation

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130) In chronic infection of hepatitis B, the antigen persists in the whole life are?:

a. All answers

b. HBeAg

c. HBcAg

d. HBsAg

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131) The T-cell receptor is:

a. Recognized antibody

b. Secreted by the T-cell

c. Recognized antigen fragments

d. Bivalent

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132) The following answers are function of B cell, EXCEPT?:

a. APC

b. Memory B cells

c. Antibody secretion

d. Complement cascade

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133)

The following statement is for MHC Class I:

a. Used to kill by cytotoxic T-cells

b. Recognized by the CD8 protein

c. Participated in helper function

d. Not able to carry an antigen fragment

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134)

The major role of the complement system is to work in conjunction with:

a. Antibodies to opsonize cells

b. Antibodies to lyse cells via the C8 and C9 components

c. T-cell receptor for production of lymphokines

d. MHC for cell recognition

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135) The TH cells produced cytokines to response the viral infection?:

a. IL-2

b. Tumor necrose factor

c. Chimokine

d. Interferon

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136)

In the complement system, the lytic pathway initiated by the complement :

a. C5

b. C1qrs

c. MBL

d. C4

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137) Biological effect of Complement C5a is:

a. Phagocytosis

b. Neutrophil activation

c. Opsonisation

d. Inflammation

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138) Papain cleaves what region of immunoglobulin?:

a. Light chain

b. Heavy chain

c. Hinge region

d. Heavy chain and Light chain

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139) Which of the following DOES NOT play a role in antigen presentation:

a. MHC class III molecules

b. Complement

c. MHC class I molecules

d. MHC class II molecules

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140) Which cell is Granulocyte:

a. Monocyte

b. Lymphocyte

c. Basophil

d. Macrophage

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141) The following hepatitis can be prevented by vaccination :

a. Hepatitis B and C

b. Hepatitis D and C

c. Hepatitis C and E

d. Hepatitis A and B

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142) All of the following are function of IgG, EXCEPT :

a. Activate complement

b. Cross placenta

c. Opsonize bacteries

d. Primary response to antigen

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143)

Which of the following is NOT true of interleukins?:

a. Produced by cells of the immune system.

b. They have receptors on the target cell.

c. Relation between cells of immune system

d. They bind antigen with a high specificity

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144)

Which cell is directly secreted immunoglobulin:

a. Plasma cell

b. B lymphocyte

c. T lymphocyte

d. Macrophage

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145) T cells secreted cytokine to activate cells in blood vessel, This phenomen is called:

a. Endocrine

b. Autocine

c. Paracrine

d. All answers

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146) The following statement are for Target cell lysis and destruction, EXCEPT:

a. Complement binding to IgG and IgM which have bound to epitopes on the target cell

b. Perforin released from antigen-specific cytotoxic T-cells

c. Complement binding to IgE which have bound to epitopes on the cell surface

d. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

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147) Which cell is Monocyte:

a. CD14

b. CD8

c. CD4

d. CD15

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148) The following cells are cells mediated immunity in adaptive immune response?:

a. All answers

b. T cells

c. B cells

d. Tc cells

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149) Immunoglobulins do which of the following?:

a. All of the above

b. Complement fixation

c. Opsonisation

d. Antigen binding

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150) Which of the following are true statements:

a. IgD provides immunization

b. IgM and IgG can fix complement

c. IgE lyses allergen

d. IgA can fix complement

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151) The Natural Killer Cells work in the immune system :

a. Kill extracellular antigen

b. Adaptive immunity and Innate immunity

c. Innate immunity

d. Adaptive immunity

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152) The average incubation period of Hepatitis A is?:

a. 60 days

b. 15 days

c. 7 days

d. 30 days

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153) The function of major histocompatibility complex is:

a. Bind epitope for presentation to T-cells

b. Bind complement for cell lysis

c. Bind antibody for cytokine secretion

d. Degrade T4 and T8 polypeptides

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154)

All of the following are true of antigen, EXCEPT:

a. They contain epitopes.

b. They will react with antibodies.

c. They contain paratopes

d. They contain antigenic determinants.

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155) The incubation period of HBV in the body is?:

a. 45-180 days

b. 30-90 days

c. 30-60 days

d. 60-100 days

156 / 321

156) Which of the following statements about leukocyte function is false?:

a. Eosinophils release histamine .

b. Eosinophils kill parasites

c. Neutrophils phagocytose pathogens .

d. Leukocytes are cells of the immune response.

157 / 321

157) Biological effect of Complement C2b is:

a. Anaphylaxis

b. Opsonisation

c. Edema

d. Phagocytosis

158 / 321

158) The lectin pathway of the complement is initiated by:

a. Factor B

b. C3

c. MBL

d. C1qrs

159 / 321

159)

IgE produce by :

a. B-cells

b. Mast cells

c. Plasma cells

d. T-cells

160 / 321

160) The following answers are true for IgM antibodies, EXCEPT:

a. Pentametric form

b. Anti infectious

c. Cause of allergy

d. Fix complement

161 / 321

161) The initial complement component that is bound by complement-fixing antibodies is:

a. C3b

b. C1s

c. C1q

d. C5a

162 / 321

162) The variable regions in the light chains participate in:

a. Epitope binding.

b. Affinity of the complement receptors.

c. Interaction of the Fab with cytokines.

d. Fc receptor binding.

163 / 321

163) The pathway of the complement that can lyse bacteria is:

a. Classical pathway

b. Lytic pathway

c. Lectin pathway

d. Alternative pathway

164 / 321

164)

T-cell antigen receptors are distinguished from antibodies by which of the following :

a. T-Cell receptors are glycosylated

b. T-cell receptors must interact with antigen

c. T-Cell receptors bind various cytokines

d. T-Cell receptors bind complement to lyse cells

165 / 321

165) These blood cells have memory after pathogens infection, EXCEPT? TH cells?:

a. B cells

b. Tc cells

c. Macrophages

166 / 321

166) The following immunoglobulin can opsonize antigen during acute phase infection?:

a. IgM

b. IgE IgA

c. IgG

167 / 321

167) The following cells are proliferated from myloid progenitor :

a. Lymphocytes

b. Dendritic cells

c. TH1

d. B cells

168 / 321

168)

Which of the following causes AIDS ?:

a. TMV

b. Retrovirus

c. Fungus

d. Bacteria

169 / 321

169) Cytokines are produced by cells of the immune system in response to various antigen,
EXCEPT:

a. Opsonization antigen

b. Facilitate cell lysis

c. Cause histamine release

d. Activate cell function

170 / 321

170) The following organs do not affect by hepatitis virus, EXCEPT:

a. Brain

b. Kidneys

c. Heart

d. Liver

171 / 321

171)

The following statements are true for IgE, EXCEPT:

a. They bind to mast cells

b. Can cross the placental barrier

c. They produce allergic reaction

d. The least immunoglobulin in the plasma

172 / 321

172)

The Biological Effects of C3b is :

a. Phagocyte activation

b. Susceptibility to bacterial infections

c. Lack of opsonisation

d. Anaphylaxia

173 / 321

173) Which of the following require the Thymus?:

a. B cel apoptosis

b. B cellsmaturation

c. T cells maturation

d. T cells rogenitor

174 / 321

174)

Which of the following is NOT a structural chain in class I MHC?:

a. β2 –microglobin

b. β1

c. α1

d. α2

175 / 321

175) The first sign of infection is the characteristic appearance of ?:

a. HBsAb

b. HBcAb

c. HBsAg

d. HBeAg

176 / 321

176) Which of the following statements about HBV is NOT correct?:

a. Can replicate

b. RNA virus

c. Parenteral route

d. Hepato carcinoma

177 / 321

177) Antigen-antibody reactions can result in the following:

a. Complement fixation

b. Virus neutralization

c. All answers

d. Killed antigen

178 / 321

178)

Complement Deficiencies of C5, C6, C7, C8 and C9 can causes :

a. Anaphylaxia

b. Susceptibility to pyogenic bacterial infections

c. Inability to attack the Gram-negative bacteria

d. Lack of opsonisation

179 / 321

179) The tests below show that patient has an chronic infection of HBV?:

a. HBsAb negative

b. HBcAb positive

c. All answers

d. HBsAg positive

180 / 321

180)

To stabilise the C3 convertase of the alternative pathway, the factors below are useful :

a. Factor F

b. C1-INH

c. Factor P

d. C3-BP

181 / 321

181) The following answer is the best marker for Tc cells?:

a. CD4

b. CD21

c. CD3

d. CD8

182 / 321

182) These organ is primary lymphoid organ of human?:

a. Lymph node

b. Spleen

c. Thymus

d. Tonsil

183 / 321

183) The first immunoglobulin secreted by B cells to make up memory cells is?:

a. IgM

b. IgD

c. IgG

d. IgA

184 / 321

184) Which of the immune cells/molecules are effective to neutralise and opsonse extracellular
pathogens?:

a. T cells

b. Antibodies

c. B cells

d. Complement

185 / 321

185) Which of the following components of the adaptive immune system secretes immunoglobulin
(Ig)?:

a. CD4+ activated T cell

b. Resting lymphocytes (B cell, T cell)

c. Activated B cell (plasma cell)

d. CD8+ cytotoxic T cell (CTL)

186 / 321

186) Each of the following statement is a characteristic of antibodies, EXCEPT:

a. They have four glycoprotein chains

b. They are phagocytes

c. They have specific receptor for antigen

d. They contain variable region

187 / 321

187) Which of the following immunoglobulin is first synthesized in an immune system to response
an pathogen?:

a. IgA

b. IgG

c. IgM

d. IgE

188 / 321

188) The hapten carrier conjugate can activate B cells to secrete antibody :

a. Immunoglobulin

b. Antigen

c. Immunoglobulin-Epitope

d. Antigenic determinant

189 / 321

189) The following answer is the function of IgM, EXCEPT :

a. Activate complement

b. Opsonize bacteries

c. Cross placenta

d. Primary response to antigen

190 / 321

190)

The immunoglobulin Joining chain (J-chain) is:

a. Produced by T-Cells

b. Associated with IgM and IgA

c. Produced by mast cells

d. Associated with IgM and IgG

191 / 321

191)

One principal function of complement is to:

a. Bind antibodies attached to cell surfaces and to lyse these cells

b. Mediate the release of histamine

c. Phagocytize antigens

d. Inactivate perforins

192 / 321

192) B cells that produce large amounts of antibody are called?:

a. Memory B cells

b. T cells

c. Neutrophils

d. Plasma cells

193 / 321

193) Which of the following is NOT a structural chain in class II MHC?:

a. α2

b. α1

c. β 1

d. α3

194 / 321

194)

Which of the following represent immune system dysfunctions:

a. Severe immunodeficiency

b. Facilitated by antibodies

c. Mast cells release histamine

d. T cells proliferation

195 / 321

195) Which cells secreted most cytokine in innate immune:

a. Macrophage

b. T lymphocyte

c. Plasma cell

d. B lymphocyte

196 / 321

196) The following immunoglobulin has extra domain and long tail :

a. IgE

b. IgA

c. IgM

d. IgG

197 / 321

197) The Complement that produce anaphylactic much more potent is:

a. C2b

b. C4a

c. C3a

d. C5a

198 / 321

198) Which of the following bacteriocidal mechanisms is oxygen dependant?:

a. Lactoferrin

b. Defensins

c. NADPH oxidation

d. Hydrolytic enzymes

199 / 321

199) The answers below are characteristic of antigen, EXCEPT:

a. Contain paratopes

b. React with antibody

c. Are toxin

d. Contain epitopes

200 / 321

200) Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Polio

b. Hepatitis B

c. Pertussis

d. Rabies

201 / 321

201)

Immediate hypersensitivity reactions are below, EXCEPT:

a. The consequence of antigen-antibody reactions

b. Phagocytosis

c. If the antigen is an allergen

d. Result from histamine release

202 / 321

202) Which type of antibody is MOST effective in activating complement?:

a. IgG1

b. IgG3

c. IgG2

d. IgM

203 / 321

203) Identity the phagocytic cells from the following combinations:

a. Lymphocyte and eosinophil

b. Macrophage and neutrophil

c. Macrophage and eosinophil

d. Eosinophil and neutrophil

204 / 321

204) Light chains are :

a. Have only a constant region

b. Specific for each class of antibody

c. Reactive with antigen

d. Complement fixation

205 / 321

205) Which of these factors can cause hepatitis?:

a. All of the above

b. Viruses

c. Malfunctioning immune system

d. Drugs and alcohol

206 / 321

206) The following answer is NOT true for interleukins?:

a. Produced by T cells

b. Produced by antigen

c. Regulation between cells

d. They are not in stock

207 / 321

207) Which cell is T helper:

a. CD4

b. CD15

c. CD14

d. CD8

208 / 321

208)

The function of Natural Killer cell is:

a. Response to antibody

b. Damaged the target cell membrane

c. Response to bacteria infection

d. Kill pathogen

209 / 321

209) Which immunoglobulin is used to test for blood group:

a. IgE

b. IgM

c. IgG

d. IgA

210 / 321

210) Which of the following technic is the best method to detect early infection of hepatitis?:

a. ELISA

b. Agglutination

c. RIA

d. PCR

211 / 321

211)

Which of the following is NOT true of interleukins:

a. They are cytokines which can be produced by various cells of the immune system.

b. They are hormones which allow one cell to communicate with another cell.

c. They are in need of receptors on the target cell in order to mediate their effects.

d. They are able to bind antigen with a high level of specificity

212 / 321

212)

Individuals unable to make the C4b would be expected to have frequent infections of the :

a. Bacteria

b. Thalassemia

c. Liver disease

d. Diabetis

213 / 321

213)

Clinical abnormalities of the Immune system can result from the activities below, EXCEPT:

a. Bacterial infection

b. Abnormal lymphocyte proliferation

c. T cell secrete cytokine

d. HIV Infection

214 / 321

214) The Complement that gives Anaphylotoxin much potent is:

a. C3a

b. C5a

c. C2b

d. C4a

215 / 321

215) The following cells of immune system cam make IgE:

a. Mast cells

b. Eosinophils

c. Mast cells and Eosinophils

d. Monocytes

216 / 321

216) The answer below is/are artificial active immunization?:

a. Killed organisms and Attenuated organisms

b. Attenuated organisms

c. Killed organisms

d. Exposure to the infections

217 / 321

217) The following immunoglobulin(s) become monomer when they attaché antigen :

a. IgG

b. IgM

c. IgA

d. IgE

218 / 321

218)

Which of the following is antiviral:

a. Lysozyme

b. Hormone

c. Interferon

d. Protein

219 / 321

219) Class II MHC proteins are:

a. Used to kill cytotoxic T-cells

b. Participate in T helper function

c. Not able to carry an epitope

d. Recognized by the CD8 protein

220 / 321

220) The much potent anaphylotoxin of the complement is:

a. C5a

b. C2b

c. C4a

d. C3a

221 / 321

221) The C5 convertase of Classic and Lectin pathway is:

a. C4b2a3b

b. C3bBb3b

c. C4b2b3a

d. C4b2a4b

222 / 321

222) The tetanus vaccine is prepare from ?:

a. Killed antigen

b. Toxin antigen

c. Virulence antigen

d. Inactivated antigen

223 / 321

223) Which part of antibody lack of constant domain:

a. VL

b. CL and CH

c. CH

d. CL

224 / 321

224) The following statements are true for Class I MHC molecules, EXCEPT :

a. Tc cells kill an infected cells

b. On the APC cells membrane

c. Participated in Th function

d. Recognized by the CD8

225 / 321

225) The component of immune system that can cause fever is :

a. Immunoglobulin

b. Complement

c. T lymphocytes

d. Macrophage

226 / 321

226) Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgM

b. IgA

c. IgE:

d. IgG

227 / 321

227) The following characcteristic is common for T and b cells?:

a. Polypeptide chains

b. have constant regions

c. able to fix complement

d. Recognize antigen

228 / 321

228) The first screening test to detect HBV infection is?:

a. HBcAg

b. HBcAb

c. HBsAb

d. HBsAg

229 / 321

229) B cells recognised antigen presented by APC?:

a. Nonself – antigen

b. T-independent antigen

c. T-dependent antigen

d. Self – antigen

230 / 321

230)

Immunoglobulins are chemically:

a. Glycogens

b. Glycoproteins

c. Glycolipids

d. D. Lipo-proteins

231 / 321

231) The following tests show that patient got chronic infection of HCV?:

a. Anti-HCV positive

b. ALT elevated and Anti-HCV positive

c. IgM positive

d. ALT elevated

232 / 321

232) Which of the following virus is NOT transmitted through the parenteral route?:

a. Hepatitis B

b. Hepatitis C

c. Hepatitis D

d. Hepatitis A

233 / 321

233) The following answers are true for phagocytosis, EXCEPT:

a. NK cell

b. Opsonisation

c. Ingest pathogen

d. Supported by complement

234 / 321

234) Immunity acquired after an infection is?:

a. Active immunity

b. Passive immunity

c. Innate immunity

d. Response immunity

235 / 321

235)

Which of these cell types can play a primary role in attacking and killing cancer cells?:

a. Mast cell

b. T cell

c. Cytotoxic

d. Platelet

236 / 321

236)

Class of immunoglobulins occurs :

a. Immunizations, going from IgM to IgG

b. Causes the histamine release

c. Binds complement

d. Mediates immunoglobulin class switching

237 / 321

237) The following statement are for Class I MHC proteins, EXCEPT:

a. Recognized by the CD8 protein

b. Participate in T helper function

c. Killed target cells by Tc cells

d. Able to carry an antigen fragment

238 / 321

238) The azerophilic granule used to facilitate phagocytosis:

a. Parasite

b. Mycose

c. Bacteria

d. Virus

239 / 321

239) All of the following statements are true for the diagnosis of HBV infection, EXCEPT?:

a. Glucose test

b. Serological HBV

c. Bilirubin

d. Liver enzyme

240 / 321

240) Which of the following antibody fragments consists of a dimer of the heavy-chain constant
region but lacks the CH1 domains?:

a. F(ab)

b. Fab

c. Fc

d. F(ab)’2

241 / 321

241) Which lymphocyte response to HBV infectin?:

a. Tc

b. B cells

c. Macrophage

d. Th

242 / 321

242) Variable regions of immunoglobulin are:

a. Specific recognition of antigen

b. N-terminal of heavy chains

c. C-terminal of heavy chains

d. Able to fix complement

243 / 321

243)

Which of the followings are NOT TRUE regarding an immune response:

a. The T4 serves an auxiliary role with MHC class II proteins in helper cell reactions

b. Lymphokines are produced by T-cells in response to antigen presentation by antibody

c. The T8 serves an auxiliary role with MHC class I proteins in cytotoxic reactions

d. The principal function of the T3 complex is signal transduction to the cell's interior

244 / 321

244) When hepatitis vaccin start to use since year?:

a. 1960

b. 2002

c. 199000%

d. 1985

245 / 321

245) The function of T cytotoxic lymphocyte is?:

a. Lyse paasite

b. Lyse pathogen

c. Lyse bacterie

d. Lyse target cell

246 / 321

246)

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgM

b. IgE

c. IgG

d. IgA

247 / 321

247)

The followings statement are FALSE for Target cell lysis and destruction :

a. Tc recognizing specific epitopes

b. C3b fix to IgE which have epitopes

c. Perforin released from Tc

d. C3b fix to IgG and IgM which have epitopes

248 / 321

248)

The functional activity of the T-cell:

a. Is related with CD4 or CD8 associated polypeptides

b. Occurs after recognition of an epitope

c. Is related with CD4 or CD8 associated polypeptides, Occurs after recognition of an epitope, Can be mediated through cytokines

d. Can be mediated through cytokines

249 / 321

249) The first immunoglobulin response to the viral hepatitis A infection is?:

a. IgE IgM

b. IgG

c. IgA

250 / 321

250) The vaccine prepared from living and inactivated microbe is considered as?:

a. Denatured

b. Antibody

c. A toxoid

d. Atenuated vaccin

251 / 321

251)

One principal function of the Class I and Class II major histocompatibility complex is to :

a. Mediate immunoglobulin class

b. Stimulate production of interleukins

c. Transduce the signal to the T-cell interior

d. Present antigen for recognition by the T-cell receptor

252 / 321

252)

Which of the following immunoglobulin can across placenta with the highest concentration?:

a. IgG2

b. IgG3

c. IgG4

d. IgG1

253 / 321

253) The cells that have azerophilic granule to facilitate phagocytosis is:

a. Mast cells

b. Basophils

c. Neutrophils

d. Monocytes

254 / 321

254)

Which of the followings are TRUE regarding an Immune response :

a. The T8 serves an auxiliary role with MHC class II in cytotoxic reactions

b. The T4 serves an auxiliary role with MHC class I in helper cell reactions

c. The function of the T3 complex is signal to the cell's interior after recognition the antigen

d. The T4 secrete antibody

255 / 321

255)

The disease below can cause allergic reaction:

a. Thalassemia

b. Asthma

c. Cancer

d. Hepatitis

256 / 321

256) Which of the followings are TRUE regarding an Immune response:

a. The T4 support MHC class I in helper reactions

b. The T8 support MHC II in cytotoxic reactions

c. The T3 complex is signal to the cell's interior to recognize antigen

d. The T4 secrete antibody

257 / 321

257) The following answer is specific for antigen:

a. Heavy chain

b. Fab region

c. Hinge region

d. Fc region

258 / 321

258)

Superantigens presented to T cells by :

a. Mast cell

b. Monocyte

c. B cell

d. APC

259 / 321

259) Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis A virus

b. Hepatitis D virus

c. Hepatitis C virus

d. Hepatitis B virus

260 / 321

260)

Organ transplantation of human from one place to another is called:

a. Autograft

b. Xeno-graft

c. Allo-graft

d. ISO-graft

261 / 321

261)

The light chains of antibodies are distinguished by:

a. Their constant specific region

b. The J-chains that bind to them

c. Their variable region domains

d. Kappa or lambda types

262 / 321

262)

In acute infection of Hepatitis B, the typical serologic course are:

a. HBsAg

b. HBcAg

c. HBcAb

d. HBsAb

263 / 321

263) The following statement are true for Cytokines, EXCEPT:

a. Secreted by specialized cells

b. Control and regulate the immune response

c. Lymphokines are cytokines

d. Are complement

264 / 321

264)

The major role of the complement C3b is to work in conjunction with:

a. Antibodies to opsonize cells

b. MHC for cell recognition

c. Antibodies to lyse cells antgen

d. T-cell for production of lymphokines

265 / 321

265) How many receptors for antigen on the surface of T lymphocyte:

a. 4

b. 1

c. 2

d. 10

266 / 321

266) The Natural Killer T Cells work in the immune system :

a. Adaptive immunity

b. Link between Adaptive and Innate immune

c. Adaptive immunity and Innate immunity

d. Innate immunity

267 / 321

267)

The factor that dissociated the initiation of C1qrs in the classical pathway is:

a. Factor F

b. C3-BP

c. C1-INH

d. Factor P

268 / 321

268)

The followings statement are TRUE, EXCEPT:

a. MHC II carrying antigen presented to Tc

b. MHC II bind antigen and recognized by the Th

c. MHC I presented on all cells of the immune

d. MHC I bind antigen and recognized by the Tc

269 / 321

269)

Graft between identical twins is called:

a. Auto graft

b. Allograft

c. Xeno-graft

d. Iso graft

270 / 321

270) The following statements are true for the antigenic determinant :

a. Small part of the antigen

b. Is the combining site of an antibody

c. Is paratope and Small part of the antigen

d. Is paratope

271 / 321

271)

The following statements are true for Antibodies, EXCEPT:

a. Made of heavy and light chains

b. Composed of variable and constant regions

c. They have hypervariable region

d. Non immunogen

272 / 321

272)

The following statements are true for Immunoglobins, EXCEPT:

a. Possess both variable and constant regions

b. Are antibodies

c. All have receptors for complement

d. Five major classes IgM, IgG, IgA, IgD, IgE

273 / 321

273)

Clinical abnormalities of the Immune system can result from the following statement, EXCEPT:

a. T cells proliferation

b. Abnormal lymphocyte proliferation

c. HIV Infection

d. Deficiency diseases

274 / 321

274)

One principal function of complement is not true:

a. Lyse target cells

b. Activate perforins

c. Mediate the release of histamine

d. Phagocytize antigens

275 / 321

275)

All of the following are true with respect to IgM antibodies, EXCEPT :

a. They mediate allergic reaction

b. They are glycoproteins

c. They occur on the surface of lymphocytes

d. They fix complement

276 / 321

276)

Light chains are:

a. Not specific for each class of antibody

b. Have only a constant region

c. Reactive with antigen

d. Specific for each class of antibody

277 / 321

277) Which kind of cells worked in innate immune system and response to the tumor cells?:

a. B cells

b. T cells

c. NK cells

d. Macropages

278 / 321

278) The variable regions in the heavy chains participate in:

a. Cellular receptor

b. Cytokine receptor

c. Antigen receptor

d. Complement receptor

279 / 321

279) Which of the following immune cells are effective to destroying intracellular pathogens:

a. B cells

b. T helper cells

c. T cytolytic cells

d. Antibodies

280 / 321

280)

All of the following are true about antibodies, EXCEPT:

a. They are polypeptide

b. They occur on the surface of B-lymphocyte

c. They are glycoproteins.

d. They fix complement.

281 / 321

281) The following statement are MOST closely related to each, EXCEPT:

a. Antigen

b. Antibody

c. Allergen

d. Epitope

282 / 321

282)

Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:

a. Halitosis

b. Botulism

c. Phagocytosis

d. Chemotaxis

283 / 321

283) Which organ does hepatitis affect?:

a. Heart

b. Kidneys

c. Brain

d. Liver

284 / 321

284) The following answer is the function of IgG, EXCEPT :

a. Activate complement

b. Primary response to antigen

c. Opsonize bacteries

d. Cross placenta

285 / 321

285) Which nonspecific defense cells specialize in attacking cancer cells and virus-infected cells?:

a. B cells

b. Macrophages

c. TH cells

d. NK cells

286 / 321

286) The following statement is true for helper T-cells :

a. Helper cells recognize antigen with MHC class I

b. Cytotoxic cells recognize antigen with MHC class II

c. Helper cells recognize antigen with MHC class I and II

d. Helper cells recognize antigen with MHC class II

287 / 321

287) Which of the following statement is related to IgG physiology in humans?:

a. IgG crosses the placental barrier, and thereby provides passive immunity to the fetus.

b. It is confined to the bloodstream, giving the host protection against blood-borne pathogens.

c. Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.

d. It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.

288 / 321

288) In chronic infection of hepatitis B, the antibody persists in the whole life is?:

a. HBsAb

b. HBsAg

c. HBcAb

d. HBcAg

289 / 321

289)

Which immunoglobulin is the principal one that is unkown function:

a. IgG

b. IgA

c. IgD

d. IgM

290 / 321

290) Biological effect of Complement C4a is regulated by:

a. Factors H & I

b. C4-BP

c. Factor I

d. C3-INA

291 / 321

291) The following cells of immune system cam make inflammation:

a. Mast cells

b. Mast cells and Basophils

c. Basophils

d. Monocytes

292 / 321

292)

In the alternative pathway of the complement system, the factors below are useful to prevent the generation of C3 convertase :

a. C3-BP

b. Factor F

c. Factor P

d. C1-INH

293 / 321

293)

Each of the following is a characteristic of antibodies, EXCEPT :

a. They contain carbohydrates

b. They are only secreted by T-cells

c. They combine specifically with antigen

d. They are proteins with variable and constant regions

294 / 321

294) The major function of major histocompatibility complex for antigen intracellular is:

a. Presentation antigen to Th-cells

b. Bind complement for cell lysis

c. Presentation antigen to Tc-cells

d. Degrade Th and Tc

295 / 321

295)

The functional activity of the T-cell:

a. All answers

b. Occurs after recognition of an epitope

c. Can be mediated through cytokines

d. Is related with CD4 or CD8 associated polypeptides

296 / 321

296)

The immunoglobulin class which is the second abundant in the normal adult is:

a. IgG

b. IgD

c. IgE

d. IgA

297 / 321

297)

T-cell receptors or antibodies react with antigens:

a. Because both 'have light chain and heavy chain polypeptides

b. Because both are made by lymphocytes

c. Because they have specific receptors for antigen

d. Cause histamine release

298 / 321

298)

One principal function of the Class I and Class II major histocompatibility complex is to:

a. Stimulate production of interleukins

b. Transduce the signal to the T-cell interior

c. Help T cell for the recognition Antigen

d. Mediate immunoglobulin class

299 / 321

299) The two types of lymphocytes are ?:

a. T and B cells

b. Erythrocyte and T cells

c. Platelet and Erythrocyte

d. Platelet and B cells

300 / 321

300) The following viral hepatitis are chronic hepatitis, EXCEPT?:

a. Hepatitis A

b. Heepatitis C

c. Hepatitis B

d. Hepatitis D

301 / 321

301) Identity the phagocytic cells that have Toll like Receptor on their membrane:

a. Neutrophil

b. Macrophage

c. Basophil

d. Eosinophil

302 / 321

302) The Cytotoxic T cells kill the cells/molecules below:

a. Bacteria

b. Infected cells

c. Intracellular antigen

d. Extracellular antigen

303 / 321

303) The region of immunoglobulin(s) can be flexible:

a. Hinge region

b. Fc region

c. Heavy chain

d. Fab region

304 / 321

304)

What is the term used to describe white blood cells migrating toward bacteria? :

a. Phagocytosis

b. Zeiosis

c. Phototaxis

d. Chemotaxis

305 / 321

305)

In the complement system, the classic pathway initiates by the complement :

a. C4

b. MBL

c. C5

d. C1qrs

306 / 321

306)

All of the following are true, EXCEPT:

a. The variable contain the antigen recognition site

b. IgM antibody is pentamer

c. An epitope is a portion of an antigen

d. IgG antibody is pentavalent

307 / 321

307) Regulatory T cells (Treg cells), formerly known as ?:

a. Natural T reg

b. Suppressor T cells

c. CD4+ T reg

d. Adaptive T reg

308 / 321

308) The following viral hepatitis is enteric hepatitis?:

a. Heepatitis C

b. Hepatitis D

c. Hepatitis A

d. Hepatitis B

309 / 321

309) The function of cytokines are :

a. Production of complement

b. Regulation the immune cells

c. Bind to MHC class I

d. Specifically recognize antigens

310 / 321

310) The family of Hepatitis B virus is named:

a. Flavivirus

b. Hepadnavirus

c. Retrovirus

d. CMV

311 / 321

311) Platelets can produce by those organs:

a. Bone marrow

b. Thymus

c. Liver

d. Spleen

312 / 321

312) All of these tests show that patient has been vaccinationated against HBV, EXCEPT?:

a. HBsAg negative

b. IgM positive

c. HBsAb positive

d. HBcAb Negative

313 / 321

313)

Which of the following statements about leukocyte function is false?:

a. Eosinophils deliver toxic granules to kill parasites. They are also involved in allergic reactions.

b. Macrophages are phagocytic cells that are involved in the adaptive response.

c. Neutrophils engulf damaged cells and pathogens by phagocytosis.

d. Leukocytes are involved in the immune response.

314 / 321

314)

Variable domains are:

a. Needed to bind complement

b. Specific recognition of antigen

c. Transported IgG across the placenta

d. Located at the N-terminal of heavy chains

315 / 321

315) The Live Attenuated Vaccines are used for the diseases below?:

a. Hepatitis A

b. Measles

c. All answers

d. Varicella zoster

316 / 321

316) The tests below show that patient is already vaccinated against HBV?:

a. HBcAb negative

b. HBsAb positive

c. All answers

d. HBsAg negative

317 / 321

317) The following statements are true for Class III MHC molecules, EXCEPT :

a. On the APC cells membrane

b. Transport protein

c. Tc cells kill an infected cells

d. Recognized by the CD8

318 / 321

318) The drug to cure post exposure of HBV is?:

a. IgA

b. IgG

c. IgE

d. IgM

319 / 321

319) The family of hepatitis C virus is?:

a. Rotavirus

b. Hepanavirus

c. Flavivirus

d. Ribovirus

320 / 321

320)

What distinguishes helper T-cells from cytotoxic T-cells :

a. Helper cells recognize antigen complexed with MHC class I molecules

b. Helper cells recognize antigen complexed with MHC class II molecules

c. Cytotoxic cells recognize antigen complexed with MHC class I molecules

d. Cytotoxic cells recognize antigen complexed with MHC class I molecules and. Helper cells recognize antigen complexed with MHC class II molecules

321 / 321

321) These cytokines secreted by T helper cell?:

a. IL-2

b. Interferon

c. Chimokine

d. TNF-α

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