Immunology Test

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Immunology Test

1 / 60

Which of the followings are TRUE regarding an Immune response :

a. The T4 secrete antibody

b. The function of the T3 complex is signal to the cell's interior after recognition the antigen

c. The T4 serves an auxiliary role with MHC class I in helper cell reactions

d. The T8 serves an auxiliary role with MHC class II in cytotoxic reactions

2 / 60

The following receptor is for T cells?:

a. Scavenger receptor

b. BCR

c. Toll like receptor

d. TCR

3 / 60

T cells secreted cytokine to activate T cells neighbering, This phenomen is called?:

a. None about

b. Autocrine

c. Endocrine

d. Paracrine

4 / 60

The following answers are function of B cell, EXCEPT?:

a. Memory B cells

b. Complement cascade

c. Antibody secretion

d. APC

5 / 60

All of the following are true, EXCEPT:

a. The variable contain the antigen recognition site

b. IgG antibody is pentavalent

c. An epitope is a portion of an antigen

d. IgM antibody is pentamer

6 / 60

All of the following are true with respect to IgG antibodies, EXCEPT:

a. They fix complement

b. They occur on the surface of B lymphocytes

c. They are glycoproteins

d. They mediate allergic reaction

7 / 60

In the alternative pathway of the complement system, the factors below are useful to prevent the generation of C3 convertase :

a. Factor P

b. Factor F

c. C1-INH

d. C3-BP

8 / 60

The first antibody secreted by B cells during infection is?:

a. IgM

b. IgE IgA

c. IgG

9 / 60

The specific type of functional activity of a T-cell following antigen recognition is determined
by:

a. CD4 or CD8 can bind antigens

b. carbohydrate side chains

c. MHC class II presenting the antigen fragment

d. Antigen receptor

10 / 60

Which of the following causes AIDS ?:

a. TMV

b. Retrovirus

c. Fungus

d. Bacteria

11 / 60

The major role of the complement system is to work in conjunction with:

a. MHC for cell recognition

b. Antibodies to opsonize cells

c. Antibodies to lyse cells via the C8 and C9 components

d. T-cell receptor for production of lymphokines

12 / 60

Identity the phagocytic cells from the following combinations:

a. Lymphocyte and eosinophil

b. Eosinophil and neutrophil

c. Macrophage and eosinophil

d. Macrophage and neutrophil

13 / 60

The following viral hepatitis are chronic hepatitis, EXCEPT?:

a. Heepatitis C

b. Hepatitis A

c. Hepatitis D

d. Hepatitis B

14 / 60

Pepsin cleaves what region of immunoglobulin?:

a. Light chain

b. Hinge region

c. Heavy chain

d. Heavy chain and Light chain

15 / 60

The screening test for HBV infection is?:

a. HBsAb

b. HBcAb

c. HBcAg

d. HBsAg

16 / 60

The following statements are true for Class III MHC molecules, EXCEPT :

a. Tc cells kill an infected cells

b. Transport protein

c. On the APC cells membrane

d. Recognized by the CD8

17 / 60

The CD marker of B cells are?:

a. CD16 and CD56

b. CD3 and CD8

c. CD3 and CD54

d. CD19 and CD21

18 / 60

These blood cells have memory after pathogens infection, EXCEPT? TH cells?:

a. Tc cells

b. Macrophages

c. B cells

19 / 60

Which of the followings are TRUE regarding an Immune response:

a. The T4 support MHC class I in helper reactions

b. The T4 secrete antibody

c. The T8 support MHC II in cytotoxic reactions

d. The T3 complex is signal to the cell's interior to recognize antigen

20 / 60

Which of the following is NOT true of interleukins:

a. They are able to bind antigen with a high level of specificity

b. They are hormones which allow one cell to communicate with another cell.

c. They are in need of receptors on the target cell in order to mediate their effects.

d. They are cytokines which can be produced by various cells of the immune system.

21 / 60

The following statements are true for Antibodies

a. Have variable region

b. Are made from alpha and beta chains

c. Contain cytoplasmic region

d. Are carbohydrates

22 / 60

Biological effect of Complement C3a is:

a. Anaphylaxis

b. Opsonisation

c. Phagocytosis

d. Edema

23 / 60

The following tests show that patient got chronic infection of HCV?:

a. ALT elevated and Anti-HCV positive

b. Anti-HCV positive

c. ALT elevated

d. IgM positive

24 / 60

The component of immune system that can cause inflammation is :

a. T lymphocytes

b. Macrophage

c. Complement

d. Immunoglobulin

25 / 60

The immunoglobulin class which is the least abundant in the normal adult is :

a. IgG

b. IgE

c. IgD

d. IgA

26 / 60

One principal function of the Class I and Class II major histocompatibility complex is to :

a. Present antigen for recognition by the T-cell receptor

b. Transduce the signal to the T-cell interior

c. Stimulate production of interleukins

d. Mediate immunoglobulin class

27 / 60

The function of MHC class II is:

a. Recognized by the CD8

b. Recognized by CD4

c. Unable to carry antigen fragment

d. Presentation Ag to Th cell

28 / 60

Where is the variable region of Immunoglobulin?:

a. CH3

b. VL

c. CL

d. CH2

29 / 60

Which of the following antibody fragments consists of a dimer of the heavy-chain constant
region but lacks the CH1 domains?:

a. Fc

b. F(ab)’2

c. Fab

d. F(ab)

30 / 60

Which of the following virus is NOT transmitted through the parenteral route?:

a. Hepatitis B

b. Hepatitis D

c. Hepatitis C

d. Hepatitis A

31 / 60

Which cell is Granulocyte:

a. Macrophage

b. Lymphocyte

c. Monocyte

d. Basophil

32 / 60

The following cells of immune system cam make IgE:

a. Mast cells and Eosinophils

b. Monocytes

c. Eosinophils

d. Mast cells

33 / 60

The following statements are true for IgE, EXCEPT:

a. The least immunoglobulin in the plasma

b. They produce allergic reaction

c. Can cross the placental barrier

d. They bind to mast cells

34 / 60

The function of Class III MHC proteins are :

a. Transport complement protein

b. Recognized antigen by CD8

c. Recognized antigen by CD4

d. Lyse antigen

35 / 60

The classical pathway of the complement is initiated by:

a. Factor B

b. C3

c. MBL

d. C1qrs

36 / 60

Regulatory T cells (Treg cells), formerly known as ?:

a. Suppressor T cells

b. Natural T reg

c. CD4+ T reg

d. Adaptive T reg

37 / 60

One principal function of complement is to:

a. Phagocytize antigens

b. Inactivate perforins

c. Bind antibodies attached to cell surfaces and to lyse these cells

d. Mediate the release of histamine

38 / 60

The following statements are true for the antigenic determinant :

a. Is paratope

b. Is the combining site of an antibody

c. Is paratope and Small part of the antigen

d. Small part of the antigen

39 / 60

Which of the following immune cells are effective to destroying intracellular pathogens:

a. T cytolytic cells

b. T helper cells

c. Antibodies

d. B cells

40 / 60

The following cells of immune system cam make inflammation:

a. Monocytes

b. Mast cells

c. Mast cells and Basophils

d. Basophils

41 / 60

The following answer is Super antigen:

a. Mycose

b. HIV

c. Staphylococus toxin

d. Virus

42 / 60

All of the following are true of antigen, EXCEPT:

a. They contain paratopes

b. They contain epitopes.

c. They will react with antibodies.

d. They contain antigenic determinants.

43 / 60

In chronic infection of hepatitis B, the antigen persists in the whole life are?:

a. HBcAg

b. HBeAg

c. HBsAg

d. All answers

44 / 60

These cytokines secreted by T helper cell?:

a. TNF-α

b. Chimokine

c. Interferon

d. IL-2

45 / 60

Which of the following immunoglobulin is first synthesized in an immune system to response
an pathogen?:

a. IgE

b. IgM

c. IgG

d. IgA

46 / 60

The following cells are cells mediated immunity in adaptive immune response?:

a. Tc cells

b. All answers

c. T cells

d. B cells

47 / 60

Which antigen is direct presented to B cell?:

a. T- dependent antigen

b. Self- antigen

c. Non self- antigen

d. T- Independent antigen

48 / 60

Individuals make up over C4a would be expected to have:

a. Anaphylaxia

b. Diabetis

c. Liver disease

d. Bacteria

49 / 60

T- independent antigen presented to the following lymphocyte?:

a. B cells

b. TH1 cell

c. Tc cells

d. TH cells

50 / 60

Humoral immunity consists of:

a. Pathological cells

b. Normal cells

c. Immunoglobulins

d. Cytotoxic cells

51 / 60

The tests below show that patient is susceptible to an HBV infection?:

a. HBcAb negative

b. HBsAg negative

c. All answers

d. HBsAb negative

52 / 60

The Cytotoxic T cells kill the cells/molecules below:

a. Intracellular antigen

b. Extracellular antigen

c. Bacteria

d. Infected cells

53 / 60

Identity the phagocytic cells that have Toll like Receptor on their membrane:

a. Macrophage

b. Neutrophil

c. Basophil

d. Eosinophil

54 / 60

An antigenic determinant is:

a. Recognized by a epitope

b. A fragment of Antigen

c. Recognized by macrophage

d. Molecule of antigen

55 / 60

IgE produce by :

a. Mast cells

b. Plasma cells

c. T-cells

d. B-cells

56 / 60

The following immunoglobulin(s) become monomer when they attaché antigen :

a. IgA

b. IgM

c. IgG

d. IgE

57 / 60

The J-chain is :

a. Facilitates secretion of pentameric lgM

b. For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

c. For immunoglobulin multimer formation

d. Made only by epithelial cells

58 / 60

The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBsAg

b. HBcAb

c. HBsAb

d. HBcAg

59 / 60

The disease below can cause by autoimmune:

a. Hepatitis

b. Cancer

c. SLE

d. Thalassemia

60 / 60

Biological effect of Complement C2b is:

a. Anaphylaxis

b. Phagocytosis

c. Opsonisation

d. Edema

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