Immunology Test

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Immunology Test

1 / 60

Which cell is T helper:

a. CD4

b. CD14

c. CD8

d. CD15

2 / 60

Each of the following is a characteristic of antibodies, EXCEPT :

a. They combine specifically with antigen

b. They contain carbohydrates

c. They are proteins with variable and constant regions

d. They are only secreted by T-cells

3 / 60

Which nonspecific defense cells specialize in attacking cancer cells and virus-infected cells?:

a. B cells

b. Macrophages

c. TH cells

d. NK cells

4 / 60

Which immunoglobulin is used to test for blood group:

a. IgE

b. IgM

c. IgA

d. IgG

5 / 60

The region of immunoglobulin term: Binds to various cellular receptors and to complement:

a. Fc region

b. Light chain

c. Fab region

d. Heavy chain

6 / 60

The chronic HCV infection develop hepatocellular carcinoma in the rate of?:

a. 20%

b. 10%

c. 50%

d. 5%

7 / 60

All of the following are true about antibodies, EXCEPT:

a. They fix complement.

b. They are polypeptide

c. They occur on the surface of B-lymphocyte

d. They are glycoproteins.

8 / 60

T cells secreted cytokine to activate cells in blood vessel, This phenomen is called:

a. Autocine

b. Endocrine

c. Paracrine

d. All answers

9 / 60

In acute infection of Hepatitis B, the typical serologic course are:

a. HBsAb

b. HBcAg

c. HBsAg

d. HBcAb

10 / 60

All of the following are true, EXCEPT:

a. An epitope is a portion of an antigen

b. The variable contain the antigen recognition site

c. IgM antibody is pentavalent

d. IgG antibody is bivalent

11 / 60

The C5 convertase of Alternative pathway is:

a. C3bBb3b

b. C4b2b3a

c. C4b2a4b

d. C4b2a3b

12 / 60

The function of MHC class II is:

a. Unable to carry antigen fragment

b. Participated in the presentation of Ag

c. Recognized by CD4

d. Recognized by the CD8

13 / 60

The first antibody secreted by B cells during infection is?:

a. IgM

b. IgE IgA

c. IgG

14 / 60

The followings statement are TRUE, EXCEPT :

a. MHC Class II carrying antigen presented to cytotoxic T cells

b. MHC Class 1 bind antigen fragments and are recognized by the Tc-cell receptor

c. MHC Class II bind antigen and are recognized by the T-cell receptor and the CD4

d. MHC Class I generally occur on all cells of the immune system

15 / 60

The following statement are for adaptive immune response, EXCEPT :

a. Can be facilitated through macrophage cells

b. Can be facilitated through T-cells

c. Can be facilitated by antibodies

d. Is mediated by the humoral and cellular of the immune

16 / 60

The following cells of immune system cam make IgE:

a. Mast cells and Eosinophils

b. Eosinophils

c. Mast cells

d. Monocytes

17 / 60

Cytokines are produced by cells of the immune system in response to various antigen,
EXCEPT:

a. Activate cell function

b. Cause histamine release

c. Opsonization antigen

d. Facilitate cell lysis

18 / 60

The following statements are true for Antibodies

a. Are made from alpha and beta chains

b. Have variable region

c. Are carbohydrates

d. Contain cytoplasmic region

19 / 60

HBV infection is characterized by the present of ?:

a. All answers

b. HBsAg

c. HBeAg

d. HBcAg

20 / 60

Class II MHC are :

a. Used to kill by cytotoxic T-cells

b. Used to participate in cytotoxic function

c. Recognized by the CD4 protein

d. Not able to carry an antigen fragment

21 / 60

The factor that stabilize C3 convertase of alternative pathway is :

a. Factor P

b. Factor I

c. Factor H

d. DAF

22 / 60

Which part of antibody lack of constant domain:

a. CL

b. CL and CH

c. VL

d. CH

23 / 60

The pathway of the complement that can lyse bacteria is:

a. Classical pathway

b. Lytic pathway

c. Alternative pathway

d. Lectin pathway

24 / 60

The Live Attenuated Vaccines are used for the diseases below?:

a. Measles

b. Varicella zoster

c. Hepatitis A

d. All answers

25 / 60

The component of immune system that can cause fever is :

a. T lymphocytes

b. Immunoglobulin

c. Macrophage

d. Complement

26 / 60

Which of the immune cells/molecules are effective to neutralise and opsonse extracellular
pathogens?:

a. T cells

b. Antibodies

c. Complement

d. B cells

27 / 60

Which of the followings are TRUE regarding an Immune response:

a. The T4 secrete antibody

b. The T8 support MHC II in cytotoxic reactions

c. The T4 support MHC class I in helper reactions

d. The T3 complex is signal to the cell's interior to recognize antigen

28 / 60

The Cytotoxic T cells kill the cells/molecules below:

a. Extracellular antigen

b. Infected cells

c. Bacteria

d. Intracellular antigen

29 / 60

Immunity acquired after an infection is?:

a. Passive immunity

b. Response immunity

c. Innate immunity

d. Active immunity

30 / 60

In the complement system, the classic pathway initiates by the complement :

a. MBL

b. C4

c. C1qrs

d. C5

31 / 60

The following statements are true for Class II MHC molecules, EXCEPT :

a. Recognized by the CD4

b. Presented antigen to Tc cells

c. Able to carry an antigen fragment

d. Used to participate in Th function

32 / 60

Complement deficiencies of C3b can cause:

a. Predisposition to SLE

b. Bacterial infection

c. Glucose oxidase deficiency

d. Overproduction of C2b

33 / 60

Which of these factors can cause hepatitis?:

a. Viruses

b. Drugs and alcohol

c. Malfunctioning immune system

d. All of the above

34 / 60

T-cell receptors or antibodies react with antigens:

a. Because both are made by lymphocytes

b. Because they have specific receptors for antigen

c. Cause histamine release

d. Because both 'have light chain and heavy chain polypeptides

35 / 60

The specific type of functional activity of a T-cell following antigen recognition is determined
by:

a. carbohydrate side chains

b. MHC class II presenting the antigen fragment

c. Antigen receptor

d. CD4 or CD8 can bind antigens

36 / 60

The following answer is Super antigen:

a. Mycose

b. Staphylococus toxin

c. Virus

d. HIV

37 / 60

The following statement are MOST closely related to each, EXCEPT:

a. Epitope

b. Antigen

c. Allergen

d. Antibody

38 / 60

The fragment of Antigen is called:

a. Immunoglbulin

b. Antigenic determinant

c. Hapten

d. Immunogen

39 / 60

Which of the following immunoglobulin can across placenta with the highest concentration?:

a. IgG2

b. IgG4

c. IgG1

d. IgG3

40 / 60

Which of the following virus is NOT transmitted through the parenteral route?:

a. Hepatitis A

b. Hepatitis C

c. Hepatitis B

d. Hepatitis D

41 / 60

The first immunoglobulin response to the viral hepatitis A infection is?:

a. IgG

b. IgA

c. IgE IgM

42 / 60

Biological effect of Complement C5a is:

a. Neutrophil activation

b. Phagocytosis

c. Inflammation

d. Opsonisation

43 / 60

The incubation period of HBV in the body is?:

a. 60-100 days

b. 30-60 days

c. 30-90 days

d. 45-180 days

44 / 60

Which of the following is antiviral:

a. Protein

b. Interferon

c. Hormone

d. Lysozyme

45 / 60

The C5 convertase of Classic and Lectin pathway is:

a. C3bBb3b

b. C4b2b3a

c. C4b2a4b

d. C4b2a3b

46 / 60

In a chronic infection of Hepatitis B, the typical serologic course are :

a. HBsAg

b. HBsAb

c. HBcAb

d. HBsAg and HBcAb

47 / 60

The Complement that produce anaphylactic much more potent is:

a. C3a

b. C5a

c. C2b

d. C4a

48 / 60

The basic monomeric Immunoglobulin unit is:

a. Synthesized by a T-cell

b. Four polypeptide chains and One of five major classes

c. One of five major classes

d. Four polypeptide chains

49 / 60

All of these tests show that patient has been vaccinationated against HBV, EXCEPT?:

a. HBsAg negative

b. IgM positive

c. HBsAb positive

d. HBcAb Negative

50 / 60

Immediate hypersensitivity reactions are below, EXCEPT:

a. If the antigen is an allergen

b. Result from histamine release

c. Phagocytosis

d. The consequence of antigen-antibody reactions

51 / 60

Hyper variability regions are present in:

a. Heavy chain only

b. Dark chain

c. Light chain only

d. Heavy and light

52 / 60

Which of the following statement is related to IgG physiology in humans?:

a. Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.

b. IgG crosses the placental barrier, and thereby provides passive immunity to the fetus.

c. It is confined to the bloodstream, giving the host protection against blood-borne pathogens.

d. It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.

53 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgM

b. IgG

c. IgE

d. IgA

54 / 60

The following statements are not true for Immunoglobins

a. All have receptors for complement

b. They have Fab

c. Five major classes of immunoglobulin

d. Possess both variable and constant regions

55 / 60

The following statements are true for Antibodies:

a. Contain heavy and light chains

b. Are carbohydrates

c. Are made from alpha and beta chains

d. Contain no carbohydrate

56 / 60

The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBsAg

b. HBcAb

c. HBsAb

d. HBcAg

57 / 60

The J-chain is :

a. For immunoglobulin multimer formation

b. For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

c. Made only by epithelial cells

d. Facilitates secretion of pentameric lgM

58 / 60

Clinical abnormalities of the Immune system can result from the activities below, EXCEPT:

a. Bacterial infection

b. T cell secrete cytokine

c. HIV Infection

d. Abnormal lymphocyte proliferation

59 / 60

The hapten carrier conjugate can activate B cells to secrete antibody :

a. Immunoglobulin

b. Antigen

c. Immunoglobulin-Epitope

d. Antigenic determinant

60 / 60

The factor that dissociated the initiation of C1qrs in the classical pathway is:

a. C3-BP

b. Factor F

c. Factor P

d. C1-INH

Your score is

The average score is 74%

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