Immunology Test

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Immunology Test

1 / 60

The Biological Effects of C3b is :

a. Susceptibility to bacterial infections

b. Phagocyte activation

c. Anaphylaxia

d. Lack of opsonisation

2 / 60

Identity the phagocytic cells from the following combinations:

a. Macrophage and eosinophil

b. Lymphocyte and eosinophil

c. Eosinophil and neutrophil

d. Macrophage and neutrophil

3 / 60

These cells can be infected by Mycobacterium tuberculosis:

a. Neutrophil

b. Macrophage

c. Lymphocyte

d. Eosinophil

4 / 60

The followings statement are TRUE, EXCEPT :

a. MHC Class 1 bind antigen fragments and are recognized by the Tc-cell receptor

b. MHC Class II bind antigen and are recognized by the T-cell receptor and the CD4

c. MHC Class I generally occur on all cells of the immune system

d. MHC Class II carrying antigen presented to cytotoxic T cells

5 / 60

Which cell is T helper:

a. CD4

b. CD15

c. CD8

d. CD14

6 / 60

Which lymphocyte are Large Granular Lymphocytes?:

a. Macropages

b. NK cells

c. T cells

d. B cells

7 / 60

The Cytotoxic T cells kill the cells/molecules below:

a. Bacteria

b. Infected cells

c. Intracellular antigen

d. Extracellular antigen

8 / 60

The following statements are true for Antibodies

a. Have variable region

b. Contain cytoplasmic region

c. Are made from alpha and beta chains

d. Are carbohydrates

9 / 60

The following statement are MOST closely related to each, EXCEPT:

a. Antigen

b. Epitope

c. Allergen

d. Antibody

10 / 60

The pathway of the complement that can lyse bacteria is:

a. Alternative pathway

b. Lectin pathway

c. Lytic pathway

d. Classical pathway

11 / 60

Molecule binding to their receptors at high affinity :

a. All answer

b. Antigen

c. Antibody

d. Cytokines

12 / 60

Which of the following is NOT true of interleukins?:

a. Relation between cells of immune system

b. They bind antigen with a high specificity

c. Produced by cells of the immune system.

d. They have receptors on the target cell.

13 / 60

An antigenic determinant is:

a. Recognized by a epitope

b. A fragment of Antigen

c. Molecule of antigen

d. Recognized by macrophage

14 / 60

The following statement is for MHC Class I:

a. Recognized by the CD8 protein

b. Used to kill by cytotoxic T-cells

c. Not able to carry an antigen fragment

d. Participated in helper function

15 / 60

The function of major histocompatibility complex for antigen in the cytosol is:

a. Transport protein

b. Presentation antigen to Tc-cells

c. Presentation antigen to Th-cells

d. Bind complement for cell lysis

16 / 60

Which of the following DOES NOT play a role in antigen presentation:

a. Complement

b. MHC class III molecules

c. MHC class II molecules

d. MHC class I molecules

17 / 60

The function of major histocompatibility complex is:

a. Bind complement for cell lysis

b. Bind epitope for presentation to T-cells

c. Bind antibody for cytokine secretion

d. Degrade T4 and T8 polypeptides

18 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgG

b. IgM

c. IgE:

d. IgA

19 / 60

The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBsAg

b. HBsAb

c. HBcAb

d. HBcAg

20 / 60

The incubation period of HBV in the body is?:

a. 30-60 days

b. 45-180 days

c. 30-90 days

d. 60-100 days

21 / 60

The Natural Killer Cells work in the immune system :

a. Adaptive immunity

b. Kill extracellular antigen

c. Innate immunity

d. Adaptive immunity and Innate immunity

22 / 60

Clinical abnormalities of the Immune system can result from the activities below, EXCEPT:

a. Abnormal lymphocyte proliferation

b. Bacterial infection

c. HIV Infection

d. T cell secrete cytokine

23 / 60

Immunity acquired after an infection is?:

a. Passive immunity

b. Innate immunity

c. Active immunity

d. Response immunity

24 / 60

Which organ does hepatitis affect?:

a. Brain

b. Heart

c. Kidneys

d. Liver

25 / 60

Which of the following statements about leukocyte function is false?:

a. Leukocytes are involved in the immune response.

b. Macrophages are phagocytic cells that are involved in the adaptive response.

c. Neutrophils engulf damaged cells and pathogens by phagocytosis.

d. Eosinophils deliver toxic granules to kill parasites. They are also involved in allergic reactions.

26 / 60

The following immunoglobulin can opsonize antigen during acute phase infection?:

a. IgG

b. IgE IgA

c. IgM

27 / 60

The following vaccines are Live Attenuated Vaccines, EXCEPT?:

a. Varicella

b. Tetanus

c. Polio

d. Hepatitis A

28 / 60

Which kind of cells worked in innate immune system and response to the tumor cells?:

a. NK cells

b. B cells

c. Macropages

d. T cells

29 / 60

The following statements are true for the antigenic determinant :

a. Small part of the antigen

b. Is paratope

c. Is paratope and Small part of the antigen

d. Is the combining site of an antibody

30 / 60

The following answer is Super antigen:

a. Virus

b. Mycose

c. HIV

d. Staphylococus toxin

31 / 60

The immunoglobulin class which is the least abundant in the normal adult is :

a. IgD

b. IgA

c. IgG

d. IgE

32 / 60

Which type of antibody is MOST effective in activating complement?:

a. IgG3

b. IgG1

c. IgM

d. IgG2

33 / 60

To stabilise the C3 convertase of the alternative pathway, the factors below are useful :

a. Factor P

b. C3-BP

c. Factor F

d. C1-INH

34 / 60

Which cell is directly secreted immunoglobulin:

a. B lymphocyte

b. Macrophage

c. Plasma cell

d. T lymphocyte

35 / 60

The major role of the complement system is to work in conjunction with:

a. T-cell receptor for production of lymphokines

b. MHC for cell recognition

c. Antibodies to lyse cells via the C8 and C9 components

d. Antibodies to opsonize cells

36 / 60

All of the following are true, EXCEPT:

a. IgM antibody is pentavalent

b. The variable contain the antigen recognition site

c. An epitope is a portion of an antigen

d. IgG antibody is bivalent

37 / 60

Which among the following is anti-bacterial ?:

a. Hormone

b. Lysozyme

c. Interferon

d. Protein

38 / 60

The J-chain of immunoglobulin is :

a. Present in IgM

b. Made by T cells

c. Made only by epithelial cells

d. Present in IgG

39 / 60

The following bonds is responsible for linking of antibody to its chains:

a. Hydrophobic forces

b. Hydrogen bonds

c. Disulfide bonds

d. Van der Waals forces

40 / 60

Humoral immunity consists of:

a. Pathological cells

b. Immunoglobulins

c. Normal cells

d. Cytotoxic cells

41 / 60

The Complement that produce anaphylactic much more potent is:

a. C3a

b. C2b

c. C4a

d. C5a

42 / 60

Which of the following virus is NOT transmitted through the parenteral route?:

a. Hepatitis A

b. Hepatitis D

c. Hepatitis B

d. Hepatitis C

43 / 60

The following statement are function of immune system, EXCEPT:

a. Facilitated by T-cells

b. Allow pathogen to infect the bod

c. Can be facilitated by antibodies

d. Mediated the humoral and cellular response

44 / 60

All of the following are true with respect to IgE molecules, EXCEPT :

a. They are the principal immunoglobulin class involved in allergic reactions.

b. They are involved in mediating anti-parasitic immune responses

c. They can effect the release of histamine.

d. They will cross the placenta and fix complement)

45 / 60

In chronic infection of hepatitis B, the antibody persists in the whole life is?:

a. HBsAg

b. HBsAb

c. HBcAg

d. HBcAb

46 / 60

One principal function of complement is not true:

a. Activate perforins

b. Mediate the release of histamine

c. Phagocytize antigens

d. Lyse target cells

47 / 60

One principal function of complement is to:

a. Mediate the release of histamine

b. Bind antibodies attached to cell surfaces and to lyse these cells

c. Inactivate perforins

d. Phagocytize antigens

48 / 60

Which of the followings are TRUE regarding an Immune response :

a. The T4 serves an auxiliary role with MHC class I in helper cell reactions

b. The T4 secrete antibody

c. The function of the T3 complex is signal to the cell's interior after recognition the antigen

d. The T8 serves an auxiliary role with MHC class II in cytotoxic reactions

49 / 60

Which of the following is NOT a structural chain in class II MHC?:

a. α2

b. α3

c. β 1

d. α1

50 / 60

Antigen-antibody reactions can result in the following:

a. Complement fixation

b. All answers

c. Killed antigen

d. Virus neutralization

51 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgA

b. IgE

c. IgM

d. IgG

52 / 60

Which of the following immunoglobulins is present normally in plasma at the highest concentration?:

a. IgM

b. IgE

c. IgG

d. IgA

53 / 60

What distinguishes helper T-cells from cytotoxic T-cells :

a. Helper cells recognize antigen complexed with MHC class II molecules

b. Helper cells recognize antigen complexed with MHC class I molecules

c. Cytotoxic cells recognize antigen complexed with MHC class I molecules

d. Cytotoxic cells recognize antigen complexed with MHC class I molecules and. Helper cells recognize antigen complexed with MHC class II molecules

54 / 60

All of the following are true with respect to IgG antibodies, EXCEPT:

a. They mediate allergic reaction

b. They occur on the surface of B lymphocytes

c. They are glycoproteins

d. They fix complement

55 / 60

The following activity is indicated T cell cytotoxic:

a. MHC-II restricted

b. B cell activation

c. MHC-I restricted

d. Epitope presented to CD4

56 / 60

Lymphocytes that develop immunocompetence in the thymus are?:

a. NK cells

b. B cells

c. LGL's

d. T cells

57 / 60

Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Polio

b. Rabies

c. Hepatitis B

d. Pertussis

58 / 60

The average incubation period of Hepatitis A is?:

a. 7 days

b. 60 days

c. 30 days

d. 15 days

59 / 60

Which type of antibody is not effective in activating complement?:

a. IgG3

b. IgG4

c. IgG1

d. IgG2

60 / 60

Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis B virus

b. Hepatitis A virus

c. Hepatitis D virus

d. Hepatitis C virus

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