Immunology Test

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Immunology Test

1 / 60

The following statements are true for Class II MHC molecules, EXCEPT :

a. Recognized by the CD4

b. Able to carry an antigen fragment

c. Presented antigen to Tc cells

d. Used to participate in Th function

2 / 60

Immediate hypersensitivity reactions are below, EXCEPT:

a. The consequence of antigen-antibody reactions

b. Phagocytosis

c. Result from histamine release

d. If the antigen is an allergen

3 / 60

Each of the following is a characteristic of antibodies, EXCEPT :

a. They combine specifically with antigen

b. They contain carbohydrates

c. They are only secreted by T-cells

d. They are proteins with variable and constant regions

4 / 60

The following vaccines is Microbial Fragment Vaccines?:

a. Clostridium tetani

b. Varicella

c. Polio

d. Hepatitis A

5 / 60

B and T cells are produced by stem cells located in:?:

a. Spleen

b. Circulatery system

c. Bone marrow

d. Liver

6 / 60

The lectin pathway of the complement is initiated by:

a. MBL

b. C3

c. C1qrs

d. Factor B

7 / 60

One principal function of the Class I and Class II major histocompatibility complex is to:

a. Stimulate production of interleukins

b. Mediate immunoglobulin class

c. Help T cell for the recognition Antigen

d. Transduce the signal to the T-cell interior

8 / 60

All of the following are true, EXCEPT:

a. An epitope is a portion of an antigen

b. The variable contain the antigen recognition site

c. IgG antibody is bivalent

d. IgM antibody is pentavalent

9 / 60

One principal function of complement is to:

a. Mediate the release of histamine

b. Phagocytize antigens

c. Inactivate perforins

d. Bind antibodies attached to cell surfaces and to lyse these cells

10 / 60

The following answer is specific for antigen:

a. Fc region

b. Fab region

c. Heavy chain

d. Hinge region

11 / 60

The initial complement component that is bound by complement-fixing antibodies is:

a. C5a

b. C3b

c. C1q

d. C1s

12 / 60

The T-cell receptor is:

a. Recognized antibody

b. Secreted by the T-cell

c. Bivalent

d. Recognized antigen fragments

13 / 60

Humoral immunity consists of:

a. Pathological cells

b. Immunoglobulins

c. Normal cells

d. Cytotoxic cells

14 / 60

In the complement system, the classic pathway initiates by the complement :

a. C4

b. C1qrs

c. C5

d. MBL

15 / 60

Which of the followings are TRUE regarding an Immune response:

a. The T8 support MHC II in cytotoxic reactions

b. The T4 secrete antibody

c. The T4 support MHC class I in helper reactions

d. The T3 complex is signal to the cell's interior to recognize antigen

16 / 60

Which type of cell destroys body cells that cause by infection?:

a. Memory B cells

b. Memory T cells

c. Cytotoxic T cells

d. Plasma B cells

17 / 60

The following immunoglobulin is used to produe vaccine?:

a. IgG

b. IgM

c. IgG4

d. IgA

18 / 60

The following statement are for Target cell lysis and destruction, EXCEPT:

a. Perforin released from antigen-specific cytotoxic T-cells

b. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

c. Complement binding to IgG and IgM which have bound to epitopes on the target cell

d. Complement binding to IgE which have bound to epitopes on the cell surface

19 / 60

The following bonds is responsible for linking of antibody to its chains:

a. Hydrogen bonds

b. Van der Waals forces

c. Hydrophobic forces

d. Disulfide bonds

20 / 60

The CD marker of B cells are?:

a. CD16 and CD56

b. CD3 and CD8

c. CD3 and CD54

d. CD19 and CD21

21 / 60

The variable regions in the light chains participate in:

a. Interaction of the Fab with cytokines.

b. Epitope binding.

c. Fc receptor binding.

d. Affinity of the complement receptors.

22 / 60

The following vaccines is not used in United State?:

a. Varicella

b. Tuberculsis

c. Polio

d. Hepatitis A

23 / 60

The tests below show that patient is susceptible to an HBV infection?:

a. All answers

b. HBsAb negative

c. HBsAg negative

d. HBcAb negative

24 / 60

The major role of the complement C3b is to work in conjunction with:

a. Antibodies to opsonize cells

b. Antibodies to lyse cells antgen

c. T-cell for production of lymphokines

d. MHC for cell recognition

25 / 60

Light chains are:

a. Have only a constant region

b. Not specific for each class of antibody

c. Specific for each class of antibody

d. Reactive with antigen

26 / 60

The incubation period of HBV in the body is?:

a. 45-180 days

b. 30-90 days

c. 30-60 days

d. 60-100 days

27 / 60

Class II MHC proteins are:

a. Recognized by the CD8 protein

b. Used to kill cytotoxic T-cells

c. Participate in T helper function

d. Not able to carry an epitope

28 / 60

In chronic infection of hepatitis B, the antigen persists in the whole life are?:

a. All answers

b. HBsAg

c. HBeAg

d. HBcAg

29 / 60

Which kind of cells worked in innate immune system and response to the tumor cells?:

a. NK cells

b. Macropages

c. T cells

d. B cells

30 / 60

Which of the following components of the innate immune system involves the release of
histamine?:

a. Eosinophil

b. Tissue mast cell

c. Macrophage

d. Neutrophil

31 / 60

All of the following are true, EXCEPT :

a. The class of an immunoglobulin is determined by its heavy chain

b. The variable regions contain the antigen recognition site

c. An antigenic determinant is a paratope

d. An epitope is a fragment of a macromolecule

32 / 60

The classical pathway of the complement is initiated by:

a. C1qrs

b. C3

c. MBL

d. Factor B

33 / 60

The function of T cytotoxic lymphocyte is?:

a. Lyse target cell

b. Lyse paasite

c. Lyse bacterie

d. Lyse pathogen

34 / 60

Complements are chemically:

a. Glycogens

b. Glycoproteins

c. Proteins

d. Lipoproteins

35 / 60

In a chronic infection of Hepatitis B, the typical serologic course are :

a. HBcAb

b. HBsAg

c. HBsAb

d. HBsAg and HBcAb

36 / 60

Which of the following DOES NOT play a role in antigen presentation:

a. MHC class II molecules

b. MHC class I molecules

c. Complement

d. MHC class III molecules

37 / 60

The following organs do not affect by hepatitis virus, EXCEPT:

a. Liver

b. Brain

c. Kidneys

d. Heart

38 / 60

The following viral hepatitis are chronic hepatitis, EXCEPT?:

a. Hepatitis D

b. Hepatitis A

c. Heepatitis C

d. Hepatitis B

39 / 60

The following answers are function of B cell, EXCEPT?:

a. Complement cascade

b. APC

c. Memory B cells

d. Antibody secretion

40 / 60

B Cells are activated by?:

a. Antibody

b. Memory cells

c. Antigen

d. Interferon

41 / 60

The following answer is NOT true for interleukins?:

a. Produced by T cells

b. Produced by antigen

c. They are not in stock

d. Regulation between cells

42 / 60

Which of the following require the Thymus?:

a. B cel apoptosis

b. B cellsmaturation

c. T cells maturation

d. T cells rogenitor

43 / 60

Which of the followings are TRUE regarding an Immune response :

a. The T4 secrete antibody

b. The function of the T3 complex is signal to the cell's interior after recognition the antigen

c. The T4 serves an auxiliary role with MHC class I in helper cell reactions

d. The T8 serves an auxiliary role with MHC class II in cytotoxic reactions

44 / 60

The family of Hepatitis B virus is named:

a. Hepadnavirus

b. Flavivirus

c. CMV

d. Retrovirus

45 / 60

Which of the following is NOT a structural chain in class I MHC?:

a. α2

b. β1

c. α1

d. β2 –microglobin

46 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgG

b. IgM

c. IgA

d. IgE

47 / 60

Which of the following is a β structural chain in class I MHC?:

a. α1

b. α2

c. β1

d. β2 –microglobin

48 / 60

The following hepatitis can be prevented by vaccination :

a. Hepatitis B and C

b. Hepatitis D and C

c. Hepatitis C and E

d. Hepatitis A and B

49 / 60

All of these tests show that patient has been infected with HBV, EXCEPT?:

a. HBsAg negative

b. HBcAg positive

c. HBcAb positive

d. HBsAb positive

50 / 60

Pepsin cleaves what region of immunoglobulin?:

a. Heavy chain

b. Heavy chain and Light chain

c. Light chain

d. Hinge region

51 / 60

Which of the following bacteriocidal mechanisms is oxygen dependant?:

a. Lactoferrin

b. Defensins

c. Hydrolytic enzymes

d. NADPH oxidation

52 / 60

Which of the following statements about leukocyte function is false?:

a. Macrophages are phagocytic cells that are involved in the adaptive response.

b. Neutrophils engulf damaged cells and pathogens by phagocytosis.

c. Leukocytes are involved in the immune response.

d. Eosinophils deliver toxic granules to kill parasites. They are also involved in allergic reactions.

53 / 60

All of these tests show that patient has been vaccinationated against HBV, EXCEPT?:

a. IgM positive

b. HBcAb Negative

c. HBsAg negative

d. HBsAb positive

54 / 60

Which among the following is anti-bacterial ?:

a. Protein

b. Interferon

c. Lysozyme

d. Hormone

55 / 60

The first antibody secreted by B cells during infection is?:

a. IgG

b. IgM

c. IgE IgA

56 / 60

Which type of antibody is MOST effective in activating complement?:

a. IgM

b. IgG1

c. IgG2

d. IgG3

57 / 60

Clinical abnormalities of the Immune system can result from the following statement, EXCEPT:

a. Abnormal lymphocyte proliferation

b. T cells proliferation

c. HIV Infection

d. Deficiency diseases

58 / 60

The first sign of infection is the characteristic appearance of ?:

a. HBsAg

b. HBcAb

c. HBsAb

d. HBeAg

59 / 60

How many serotypes of HCV in the world?:

a. 6

b. 2

c. 4

d. Many

60 / 60

HBV infection is characterized by the present of ?:

a. HBcAg

b. HBsAg

c. All answers

d. HBeAg

Your score is

The average score is 74%

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