Immunology Test

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Immunology Test

1 / 60

The following statement are true for Cytokines, EXCEPT:

a. Control and regulate the immune response

b. Lymphokines are cytokines

c. Are complement

d. Secreted by specialized cells

2 / 60

The primairy response of antibody to the HBV is?:

a. IgE

b. IgM

c. IgG

d. IgA

3 / 60

The Natural Killer Cells work in the immune system :

a. Kill extracellular antigen

b. Adaptive immunity and Innate immunity

c. Adaptive immunity

d. Innate immunity

4 / 60

The J-chain is :

a. For immunoglobulin multimer formation

b. Made only by epithelial cells

c. For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

d. Facilitates secretion of pentameric lgM

5 / 60

In the alternative pathway of the complement system, the factors below are useful to prevent the generation of C3 convertase :

a. Factor P

b. Factor F

c. C1-INH

d. C3-BP

6 / 60

The following vaccines are Live Attenuated Vaccines, EXCEPT?:

a. Polio

b. Hepatitis A

c. Varicella

d. Tetanus

7 / 60

The Complement that produce anaphylactic much more potent is:

a. C2b

b. C3a

c. C5a

d. C4a

8 / 60

All of the following are true about antibodies, EXCEPT:

a. They are polypeptide

b. They occur on the surface of B-lymphocyte

c. They are glycoproteins.

d. They fix complement.

9 / 60

The following statement are for Target cell lysis and destruction, EXCEPT:

a. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

b. Perforin released from antigen-specific cytotoxic T-cells

c. Complement binding to IgG and IgM which have bound to epitopes on the target cell

d. Complement binding to IgE which have bound to epitopes on the cell surface

10 / 60

The light chains of antibodies are distinguished by:

a. Their constant specific region

b. Kappa or lambda types

c. The J-chains that bind to them

d. Their variable region domains

11 / 60

The following statement are MOST closely related to each, EXCEPT:

a. Allergen

b. Epitope

c. Antigen

d. Antibody

12 / 60

Which cell is Granulocyte:

a. Lymphocyte

b. Monocyte

c. Macrophage

d. Basophil

13 / 60

Which cell is directly secreted immunoglobulin:

a. Macrophage

b. B lymphocyte

c. Plasma cell

d. T lymphocyte

14 / 60

Each of the following statement is a characteristic of antibodies, EXCEPT:

a. They have specific receptor for antigen

b. They have four glycoprotein chains

c. They contain variable region

d. They are phagocytes

15 / 60

The followings statement are TRUE for Target cell lysis and destruction,EXCEPT :

a. Complement binding to IgE antibodies which have bound to epitopes on the cell surface

b. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

c. Perforin released from antigen-specific cytotoxic T-cells

d. Complement binding to IgG and IgM which have bound to epitopes on the target cell

16 / 60

Which of the following immune cells/molecules are most effective to destroying intracellular
pthogens ?:

a. T cytotoxic cells

b. Plasma cells

c. T helper cells

d. B cells

17 / 60

Which of the following components of the adaptive immune system secretes immunoglobulin
(Ig)?:

a. CD4+ activated T cell

b. Resting lymphocytes (B cell, T cell)

c. Activated B cell (plasma cell)

d. CD8+ cytotoxic T cell (CTL)

18 / 60

Which of the following statements about leukocyte function is false?:

a. Neutrophils engulf damaged cells and pathogens by phagocytosis.

b. Leukocytes are involved in the immune response.

c. Macrophages are phagocytic cells that are involved in the adaptive response.

d. Eosinophils deliver toxic granules to kill parasites. They are also involved in allergic reactions.

19 / 60

What is the term used to describe white blood cells migrating toward bacteria? :

a. Zeiosis

b. Chemotaxis

c. Phagocytosis

d. Phototaxis

20 / 60

All of the following are true, EXCEPT :

a. The variable regions contain the antigen recognition site

b. The class of an immunoglobulin is determined by its heavy chain

c. An epitope is a fragment of a macromolecule

d. An antigenic determinant is a paratope

21 / 60

The TH cells produced cytokines to response the viral infection?:

a. Chimokine

b. Interferon

c. Tumor necrose factor

d. IL-2

22 / 60

Which of the following are mechanisms for neutrophil phagocytosis:

a. defensins

b. Azerophilic granules and defensins

c. Azerophilic granules

d. Hydrolytic enzymes

23 / 60

The following immunoglobulin is used to produe vaccine?:

a. IgG4

b. IgM

c. IgG

d. IgA

24 / 60

All of the following are true of antigen, EXCEPT:

a. They will react with antibodies.

b. They contain paratopes

c. They contain antigenic determinants.

d. They contain epitopes.

25 / 60

Which of the following is antiviral:

a. Interferon

b. Hormone

c. Protein

d. Lysozyme

26 / 60

The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBcAg

b. HBcAb

c. HBsAg

d. HBsAb

27 / 60

The following vaccines is not used in United State?:

a. Polio

b. Hepatitis A

c. Tuberculsis

d. Varicella

28 / 60

The component of immune system that can cause inflammation is :

a. Macrophage

b. T lymphocytes

c. Immunoglobulin

d. Complement

29 / 60

Immunoglobulins do which of the following?:

a. Opsonisation

b. All of the above

c. Complement fixation

d. Antigen binding

30 / 60

Cell mediated immunity in adaptive immune is carried out by?:

a. T cells

b. Antigen

c. Antibody

d. B cells

31 / 60

The following bonds is responsible for linking of antibody to its chains:

a. Hydrogen bonds

b. Van der Waals forces

c. Disulfide bonds

d. Hydrophobic forces

32 / 60

Biological effect of Complement C5a is:

a. Phagocytosis

b. Neutrophil activation

c. Opsonisation

d. Inflammation

33 / 60

How many receptors for antigen on the surface of T lymphocyte:

a. 2

b. 10

c. 1

d. 4

34 / 60

Graft between identical twins is called:

a. Xeno-graft

b. Iso graft

c. Allograft

d. Auto graft

35 / 60

The following disease is the cancer of lymphocyte?:

a. Mycobacterium

b. Non-Hodgkin lymphoma

c. Listeria

d. Lymphocytopenia

36 / 60

Which immunoglobulin is the principal one that is unkown function:

a. IgM

b. IgD

c. IgG

d. IgA

37 / 60

One principal function of the Class I and Class II major histocompatibility complex is to:

a. Mediate immunoglobulin class

b. Help T cell for the recognition Antigen

c. Stimulate production of interleukins

d. Transduce the signal to the T-cell interior

38 / 60

All of the following statements are true for the diagnosis of HBV infection, EXCEPT?:

a. Serological HBV

b. Liver enzyme

c. Glucose test

d. Bilirubin

39 / 60

The following antigen activate 25% of T cells:

a. HIV

b. Mycose

c. Staphylococus toxin

d. Virus

40 / 60

B and T cells are produced by stem cells located in:?:

a. Liver

b. Spleen

c. Circulatery system

d. Bone marrow

41 / 60

Which of the following antibody fragments consists of a dimer of the heavy-chain constant
region but lacks the CH1 domains?:

a. Fc

b. Fab

c. F(ab)

d. F(ab)’2

42 / 60

The following immunoglobulin has extra domain and long tail :

a. IgM

b. IgG

c. IgA

d. IgE

43 / 60

Class of immunoglobulins occurs :

a. Binds complement

b. Mediates immunoglobulin class switching

c. Immunizations, going from IgM to IgG

d. Causes the histamine release

44 / 60

The function of LGL cell is:

a. Respose to tumor cells

b. Response to antibody

c. Response to bacteria infection

d. Kill pathogen

45 / 60

Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:

a. Halitosis

b. Botulism

c. Phagocytosis

d. Chemotaxis

46 / 60

The hapten carrier conjugate can activate B cells to secrete antibody :

a. Antigen

b. Immunoglobulin-Epitope

c. Antigenic determinant

d. Immunoglobulin

47 / 60

The specific type of functional activity of a T-cell following antigen recognition is determined
by:

a. MHC class II presenting the antigen fragment

b. CD4 or CD8 can bind antigens

c. Antigen receptor

d. carbohydrate side chains

48 / 60

The following statements are true for Class III MHC molecules, EXCEPT :

a. Transport protein

b. Tc cells kill an infected cells

c. On the APC cells membrane

d. Recognized by the CD8

49 / 60

The immunoglobulin class which is the least abundant in the normal adult is :

a. IgA

b. IgG

c. IgD

d. IgE

50 / 60

Immunoglobulins are chemically:

a. Glycoproteins

b. Glycogens

c. Glycolipids

d. D. Lipo-proteins

51 / 60

All of the following are the type RNA virus, EXCEPT?:

a. Hepatitis B

b. Hepatitis C

c. Hepatitis A

d. Hepatitis E

52 / 60

The function of MHC class II is:

a. Unable to carry antigen fragment

b. Recognized by the CD8

c. Participated in the presentation of Ag

d. Recognized by CD4

53 / 60

The tests below show that patient is already vaccinated against HBV?:

a. HBsAg negative

b. HBcAb negative

c. All answers

d. HBsAb positive

54 / 60

Lymphocytes that develop immunocompetence in the thymus are?:

a. B cells

b. NK cells

c. T cells

d. LGL's

55 / 60

How many receptors for antigen on the surface of B lymphocyte:

a. 10

b. 4

c. 1

d. 2

56 / 60

The following statement are for Class I MHC proteins, EXCEPT:

a. Recognized by the CD8 protein

b. Participate in T helper function

c. Able to carry an antigen fragment

d. Killed target cells by Tc cells

57 / 60

The following statements are true for Antibodies:

a. Are carbohydrates

b. Are made from alpha and beta chains

c. Contain no carbohydrate

d. Contain heavy and light chains

58 / 60

Regulatory T cells (Treg cells), formerly known as ?:

a. Suppressor T cells

b. Adaptive T reg

c. Natural T reg

d. CD4+ T reg

59 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgA

b. IgG

c. IgE:

d. IgM

60 / 60

The following immunoglobulin can opsonize antigen during acute phase infection?:

a. IgM

b. IgG

c. IgE IgA

Your score is

The average score is 76%

Any comments?

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