Immunology Test

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Immunology Test

1 / 60

Intracellular pathogen is presented to the Tc by:

a. MHC I

b. Lymphocytes

c. TH

d. MHC II

2 / 60

Which cell is T helper:

a. CD4

b. CD15

c. CD8

d. CD14

3 / 60

The followings statement are TRUE for Target cell lysis and destruction,EXCEPT :

a. Complement binding to IgG and IgM which have bound to epitopes on the target cell

b. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

c. Perforin released from antigen-specific cytotoxic T-cells

d. Complement binding to IgE antibodies which have bound to epitopes on the cell surface

4 / 60

In chronic infection of hepatitis B, the antigen persists in the whole life are?:

a. HBeAg

b. HBsAg

c. All answers

d. HBcAg

5 / 60

Each of the following statement is a characteristic of antibodies, EXCEPT:

a. They contain variable region

b. They have four glycoprotein chains

c. They have specific receptor for antigen

d. They are phagocytes

6 / 60

The following immunoglobulin is used to produe vaccine?:

a. IgG

b. IgA

c. IgM

d. IgG4

7 / 60

Hyper variability regions are present in:

a. Light chain only

b. Heavy chain only

c. Dark chain

d. Heavy and light

8 / 60

The following activity is indicated T cell cytotoxic:

a. Epitope presented to CD4

b. MHC-I restricted

c. MHC-II restricted

d. B cell activation

9 / 60

One principal function of the Class I and Class II major histocompatibility complex is to:

a. Mediate immunoglobulin class

b. Transduce the signal to the T-cell interior

c. Help T cell for the recognition Antigen

d. Stimulate production of interleukins

10 / 60

The answer below is/are artificial active immunization?:

a. Exposure to the infections

b. Killed organisms and Attenuated organisms

c. Killed organisms

d. Attenuated organisms

11 / 60

The following statements are true for Antibodies

a. Are carbohydrates

b. Contain cytoplasmic region

c. Are made from alpha and beta chains

d. Have variable region

12 / 60

These cells can be infected by Mycobacterium tuberculosis:

a. Neutrophil

b. Lymphocyte

c. Macrophage

d. Eosinophil

13 / 60

The following vaccines is Microbial Fragment Vaccines?:

a. Polio

b. Hepatitis A

c. Clostridium tetani

d. Varicella

14 / 60

How many serotypes of HCV in the world?:

a. Many

b. 4

c. 6

d. 2

15 / 60

The Immunoglobulins are secreted by:

a. B-cells

b. Macrophages

c. T-cells

d. Plasma cells

16 / 60

The immunoglobulin Joining chain (J-chain) is:

a. Produced by mast cells

b. Associated with IgM and IgA

c. Associated with IgM and IgG

d. Produced by T-Cells

17 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgM

b. IgE:

c. IgA

d. IgG

18 / 60

Identity the phagocytic cells from the following combinations:

a. Macrophage and eosinophil

b. Macrophage and neutrophil

c. Eosinophil and neutrophil

d. Lymphocyte and eosinophil

19 / 60

The lectin pathway of the complement is initiated by:

a. C1qrs

b. C3

c. Factor B

d. MBL

20 / 60

The region of immunoglobulin term: Binds to various cellular receptors and to complement:

a. Fab region

b. Fc region

c. Light chain

d. Heavy chain

21 / 60

The Natural Killer T Cells work in the immune system :

a. Adaptive immunity and Innate immunity

b. Link between Adaptive and Innate immune

c. Adaptive immunity

d. Innate immunity

22 / 60

The Live Attenuated Vaccines are used for the diseases below?:

a. Hepatitis A

b. Measles

c. Varicella zoster

d. All answers

23 / 60

T-cell antigen receptors are distinguished from antibodies by which of the following :

a. T-Cell receptors bind complement to lyse cells

b. T-cell receptors must interact with antigen

c. T-Cell receptors are glycosylated

d. T-Cell receptors bind various cytokines

24 / 60

The function of Natural Killer cell is:

a. Response to bacteria infection

b. Kill pathogen

c. Response to antibody

d. Damaged the target cell membrane

25 / 60

What is the term used to describe white blood cells migrating toward bacteria? :

a. Phototaxis

b. Zeiosis

c. Chemotaxis

d. Phagocytosis

26 / 60

Individuals unable to make the C4b would be expected to have frequent infections of the :

a. Thalassemia

b. Bacteria

c. Liver disease

d. Diabetis

27 / 60

Biological effect of Complement C3a is:

a. Phagocytosis

b. Opsonisation

c. Anaphylaxis

d. Edema

28 / 60

Complement deficiencies of C3b can cause:

a. Predisposition to SLE

b. Bacterial infection

c. Glucose oxidase deficiency

d. Overproduction of C2b

29 / 60

Clinical abnormalities of the Immune system can result from the following statement, EXCEPT:

a. HIV Infection

b. T cells proliferation

c. Abnormal lymphocyte proliferation

d. Deficiency diseases

30 / 60

The variable regions in the heavy chains participate in:

a. Antigen receptor

b. Cytokine receptor

c. Cellular receptor

d. Complement receptor

31 / 60

All of the following are true of antigen, EXCEPT:

a. They contain epitopes.

b. They will react with antibodies.

c. They contain antigenic determinants.

d. They contain paratopes

32 / 60

Which kind of cells worked in innate immune system and response to the tumor cells?:

a. T cells

b. Macropages

c. NK cells

d. B cells

33 / 60

Which cells secreted most cytokine in innate immune:

a. Plasma cell

b. Macrophage

c. T lymphocyte

d. B lymphocyte

34 / 60

Which of the following immune cells are effective to destroying intracellular pathogens:

a. Antibodies

b. B cells

c. T cytolytic cells

d. T helper cells

35 / 60

The tests below show that patient is susceptible to an HBV infection?:

a. HBsAb negative

b. HBcAb negative

c. HBsAg negative

d. All answers

36 / 60

The drug to cure post exposure of HBV is?:

a. IgA

b. IgE

c. IgM

d. IgG

37 / 60

The following organs do not affect by hepatitis virus, EXCEPT:

a. Heart

b. Kidneys

c. Brain

d. Liver

38 / 60

The Cytotoxic T cells kill the cells/molecules below:

a. Bacteria

b. Infected cells

c. Intracellular antigen

d. Extracellular antigen

39 / 60

B cells that produce large amounts of antibody are called?:

a. Memory B cells

b. Neutrophils

c. Plasma cells

d. T cells

40 / 60

Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis G virus

b. Hepatitis B virus

c. Hepatitis E virus

d. Hepatitis A virus

41 / 60

The initial complement component that is bound by complement-fixing antibodies is:

a. C1q

b. C3b

c. C5a

d. C1s

42 / 60

The following cells of immune system cam make IgE:

a. Mast cells

b. Mast cells and Eosinophils

c. Eosinophils

d. Monocytes

43 / 60

The following statements are true for the antigenic determinant :

a. Is paratope and Small part of the antigen

b. Is paratope

c. Is the combining site of an antibody

d. Small part of the antigen

44 / 60

Light chains are :

a. Have only a constant region

b. Specific for each class of antibody

c. Reactive with antigen

d. Complement fixation

45 / 60

The family of Hepatitis B virus is named:

a. Hepadnavirus

b. CMV

c. Retrovirus

d. Flavivirus

46 / 60

Which of the following technic is the best method to detect early infection of hepatitis?:

a. ELISA

b. RIA

c. Agglutination

d. PCR

47 / 60

Superantigens presented to T cells by :

a. Monocyte

b. APC

c. B cell

d. Mast cell

48 / 60

Which lymphocyte are Large Granular Lymphocytes?:

a. B cells

b. NK cells

c. T cells

d. Macropages

49 / 60

The immunoglobulin class which is the least abundant in the normal adult is :

a. IgE

b. IgG

c. IgD

d. IgA

50 / 60

The receptor BCR for an antigen on the membrane of B cell is?:

a. Monovalent

b. None about

c. Bivalent

d. Trivalent

51 / 60

The class of an immunoglobulin is determined by:

a. The light chain

b. The heavy chain

c. The antigen

d. Class I and II MHC

52 / 60

The factor that dissociated the initiation of C1qrs in the classical pathway is:

a. C1-INH

b. Factor P

c. Factor F

d. C3-BP

53 / 60

The function of MHC class II is:

a. Recognized by CD4

b. Unable to carry antigen fragment

c. Recognized by the CD8

d. Presentation Ag to Th cell

54 / 60

The disease below can cause by autoimmune:

a. Thalassemia

b. Hepatitis

c. Cancer

d. SLE

55 / 60

Tumor Necrose Factor (TNF) produce by:

a. Tc

b. Macrophage and Tc

c. Neutrophil

d. Macrophage

56 / 60

Complements are chemically:

a. Glycogens

b. Proteins

c. Glycoproteins

d. Lipoproteins

57 / 60

The component of immune system that can cause fever is :

a. T lymphocytes

b. Macrophage

c. Complement

d. Immunoglobulin

58 / 60

The following statements are true for Antibodies, EXCEPT:

a. They have hypervariable region

b. Composed of variable and constant regions

c. Non immunogen

d. Made of heavy and light chains

59 / 60

The rabic vaccin is used to?:

a. Cure tetanus infection

b. Prevent rabie infection

c. Prevent tetanus infection

d. Cure rabie infection

60 / 60

Which of the followings are TRUE regarding an Immune response :

a. The T8 serves an auxiliary role with MHC class II in cytotoxic reactions

b. The T4 serves an auxiliary role with MHC class I in helper cell reactions

c. The function of the T3 complex is signal to the cell's interior after recognition the antigen

d. The T4 secrete antibody

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