Immunology Test – testnisset.com

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Immunology Test

1 / 60

The following activities are belong to the B-cells :

a. Act as antigen-processing cells

b. Differentiate into plasma cells

c. Receptor antigen monovalent

d. Antibodies response to antigens

2 / 60

The following hepatitis can be prevented by vaccination :

a. Hepatitis C and E

b. Hepatitis D and C

c. Hepatitis A and B

d. Hepatitis B and C

3 / 60

The C5 convertase of Alternative pathway is:

a. C4b2a4b

b. C4b2a3b

c. C4b2b3a

d. C3bBb3b

4 / 60

The following statements are true for Antibodies:

a. Are made from alpha and beta chains

b. Contain heavy and light chains

c. Contain no carbohydrate

d. Are carbohydrates

5 / 60

Biological effect of Complement C2b is:

a. Anaphylaxis

b. Edema

c. Phagocytosis

d. Opsonisation

6 / 60

These blood cells have memory after pathogens infection, EXCEPT? TH cells?:

a. Tc cells

b. B cells

c. Macrophages

7 / 60

Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:

a. Halitosis

b. Phagocytosis

c. Botulism

d. Chemotaxis

8 / 60

Platelets can produce by those organs:

a. Liver

b. Bone marrow

c. Thymus

d. Spleen

9 / 60

The T-cell receptor is:

a. Secreted by the T-cell

b. Recognized antigen fragments

c. Recognized antibody

d. Bivalent

10 / 60

The following answer is specific for antigen:

a. Fab region

b. Heavy chain

c. Fc region

d. Hinge region

11 / 60

The average incubation period of Hepatitis A is?:

a. 7 days

b. 60 days

c. 30 days

d. 15 days

12 / 60

Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis G virus

b. Hepatitis E virus

c. Hepatitis A virus

d. Hepatitis B virus

13 / 60

The following bonds is responsible for linking of antibody to its chains:

a. Hydrophobic forces

b. Van der Waals forces

c. Disulfide bonds

d. Hydrogen bonds

14 / 60

The cells that have azerophilic granule to facilitate phagocytosis is:

a. Monocytes

b. Basophils

c. Neutrophils

d. Mast cells

15 / 60

The tests below show that patient has an chronic infection of HBV?:

a. HBsAg positive

b. HBcAb positive

c. All answers

d. HBsAb negative

16 / 60

The following statements are true for IgE, EXCEPT:

a. They bind to mast cells

b. Can cross the placental barrier

c. They produce allergic reaction

d. The least immunoglobulin in the plasma

17 / 60

Myeloid cells below lived in tissue:

a. Lymphocyte

b. Macrophage

c. Neutrophil

d. Basophil

18 / 60

The following statements are true for the antigenic determinant :

a. Is paratope and Small part of the antigen

b. Is the combining site of an antibody

c. Is paratope

d. Small part of the antigen

19 / 60

Which of the following are mechanisms for neutrophil phagocytosis:

a. Azerophilic granules

b. Azerophilic granules and defensins

c. Hydrolytic enzymes

d. defensins

20 / 60

The pathway of the complement that can lyse bacteria is:

a. Classical pathway

b. Lectin pathway

c. Lytic pathway

d. Alternative pathway

21 / 60

The percentage of lymphocytes leave the thymus to become mature immunocompetent T
cells is?:

a. 2%

b. 90%

c. 10%

d. 98%

22 / 60

The J-chain is :

a. Made only by epithelial cells

b. For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

c. For immunoglobulin multimer formation

d. Facilitates secretion of pentameric lgM

23 / 60

Humoral immunity consists of:

a. Pathological cells

b. Cytotoxic cells

c. Immunoglobulins

d. Normal cells

24 / 60

In the complement system, the classic pathway initiates by the complement :

a. C5

b. C4

c. C1qrs

d. MBL

25 / 60

The following molecules can activate B cells to secrete antibody, EXCEPT:

a. Allergen

b. Antigen

c. Antigenic determinant

d. Hapten

26 / 60

One principal function of complement is not true:

a. Activate perforins

b. Lyse target cells

c. Phagocytize antigens

d. Mediate the release of histamine

27 / 60

The following statements are true for Antibodies, EXCEPT :

a. Made of heavy and light chains

b. Fc receptor for complement

c. Receptors for antigens are monovalent

d. Extra domain for IgM

28 / 60

The CD marker of B cells are?:

a. CD19 and CD21

b. CD3 and CD8

c. CD16 and CD56

d. CD3 and CD54

29 / 60

The following vaccines is not used in United State?:

a. Polio

b. Tuberculsis

c. Varicella

d. Hepatitis A

30 / 60

Which lymphocyte response to HBV infectin?:

a. Macrophage

b. Tc

c. B cells

d. Th

31 / 60

The functional activity of the T-cell:

a. Occurs after recognition of an epitope

b. Is related with CD4 or CD8 associated polypeptides

c. All answers

d. Can be mediated through cytokines

32 / 60

The following tests show that patient got chronic infection of HCV?:

a. ALT elevated

b. IgM positive

c. Anti-HCV positive

d. ALT elevated and Anti-HCV positive

33 / 60

The function of MHC class II is:

a. Recognized by the CD8

b. Recognized by CD4

c. Participated in the presentation of Ag

d. Unable to carry antigen fragment

34 / 60

The following immunoglobulin has extra domain and long tail :

a. IgA

b. IgM

c. IgG

d. IgE

35 / 60

The major histocompatibility complex proteins function to:

a. Degrade T4 and T8 polypeptides

b. Bind antigen for presentation to T-cells

c. Bind complement for cell lysis

d. Bind antibody for lymphokine production

36 / 60

Which of the followings are NOT TRUE regarding an immune response:

a. The principal function of the T3 complex is signal transduction to the cell's interior

b. The T4 serves an auxiliary role with MHC class II proteins in helper cell reactions

c. The T8 serves an auxiliary role with MHC class I proteins in cytotoxic reactions

d. Lymphokines are produced by T-cells in response to antigen presentation by antibody

37 / 60

Which cell is Monocyte:

a. CD14

b. CD8

c. CD4

d. CD15

38 / 60

Which of the following are true statements:

a. IgD provides immunization

b. IgE lyses allergen

c. IgM and IgG can fix complement

d. IgA can fix complement

39 / 60

The first screening test to detect HBV infection is?:

a. HBcAb

b. HBsAg

c. HBcAg

d. HBsAb

40 / 60

Identity the phagocytic cells from the following combinations:

a. Eosinophil and neutrophil

b. Lymphocyte and eosinophil

c. Macrophage and eosinophil

d. Macrophage and neutrophil

41 / 60

The J-chain of immunoglobulin is :

a. Present in IgG

b. Made by T cells

c. Present in IgM

d. Made only by epithelial cells

42 / 60

The type of an immunoglobulin is determined by:

a. The light chain

b. The variable region

c. The carbohydrate

d. The heavy chain

43 / 60

The function of Class III MHC proteins are :

a. Recognized antigen by CD4

b. Recognized antigen by CD8

c. Lyse antigen

d. Transport complement protein

44 / 60

The following organs do not affect by hepatitis virus, EXCEPT:

a. Liver

b. Brain

c. Heart

d. Kidneys

45 / 60

An antigenic determinant is:

a. A fragment of Antigen

b. Recognized by macrophage

c. Recognized by a epitope

d. Molecule of antigen

46 / 60

Identity the phagocytic cells that have Toll like Receptor on their membrane:

a. Neutrophil

b. Macrophage

c. Basophil

d. Eosinophil

47 / 60

Cell mediated immunity in adaptive immune is carried out by?:

a. B cells

b. Antibody

c. Antigen

d. T cells

48 / 60

Which of the following immunoglobulin can across placenta with the highest concentration?:

a. IgG2

b. IgG1

c. IgG3

d. IgG4

49 / 60

Cytokines are produced by cells of the immune system in response to various antigen,
EXCEPT:

a. Cause histamine release

b. Activate cell function

c. Facilitate cell lysis

d. Opsonization antigen

50 / 60

Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Rabies

b. Pertussis

c. Hepatitis B

d. Polio

51 / 60

The light chains of antibodies are distinguished by:

a. The J-chains that bind to them

b. Their constant specific region

c. Kappa or lambda types

d. Their variable region domains

52 / 60

Which cell is T helper:

a. CD14

b. CD4

c. CD8

d. CD15

53 / 60

Thymus growth occurs up to:

a. 5 years

b. 30 years

c. 12 years

d. 17 years

54 / 60

The drug to cure post exposure of HBV is?:

a. IgA

b. IgG

c. IgM

d. IgE

55 / 60

When hepatitis vaccin start to use since year?:

a. 199000%

b. 1960

c. 2002

d. 1985

56 / 60

All of the following are the type RNA virus, EXCEPT?:

a. Hepatitis A

b. Hepatitis B

c. Hepatitis E

d. Hepatitis C

57 / 60

The Cytotoxic T cells kill the cells/molecules below:

a. Bacteria

b. Intracellular antigen

c. Extracellular antigen

d. Infected cells

58 / 60

The following statement are function of immune system, EXCEPT:

a. Mediated the humoral and cellular response

b. Allow pathogen to infect the bod

c. Facilitated by T-cells

d. Can be facilitated by antibodies

59 / 60

What distinguishes helper T-cells from cytotoxic T-cells :

a. Helper cells recognize antigen complexed with MHC class I molecules

b. Cytotoxic cells recognize antigen complexed with MHC class I molecules and. Helper cells recognize antigen complexed with MHC class II molecules

c. Cytotoxic cells recognize antigen complexed with MHC class I molecules

d. Helper cells recognize antigen complexed with MHC class II molecules

60 / 60

B Cells are activated by?:

a. Memory cells

b. Antigen

c. Antibody

d. Interferon

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