Immunology Test

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Immunology Test

1 / 60

The major role of the complement C3b is to work in conjunction with:

a. Antibodies to opsonize cells

b. Antibodies to lyse cells antgen

c. T-cell for production of lymphokines

d. MHC for cell recognition

2 / 60

Each of the following statement is a characteristic of antibodies, EXCEPT:

a. They have four glycoprotein chains

b. They are phagocytes

c. They have specific receptor for antigen

d. They contain variable region

3 / 60

The following statements are true for Antibodies, EXCEPT:

a. Made of heavy and light chains

b. They have hypervariable region

c. Composed of variable and constant regions

d. Non immunogen

4 / 60

The following hepatitis can be prevented by vaccination :

a. Hepatitis C and E

b. Hepatitis D and C

c. Hepatitis A and B

d. Hepatitis B and C

5 / 60

The following statements are not true for Immunoglobins

a. Five major classes of immunoglobulin

b. They have Fab

c. All have receptors for complement

d. Possess both variable and constant regions

6 / 60

The following immunoglobulin is used to produe vaccine?:

a. IgA

b. IgM

c. IgG4

d. IgG

7 / 60

All of these tests show that patient has been infected with HBV, EXCEPT?:

a. HBcAb positive

b. HBsAb positive

c. HBsAg negative

d. HBcAg positive

8 / 60

Which cell is directly secreted immunoglobulin:

a. B lymphocyte

b. Macrophage

c. T lymphocyte

d. Plasma cell

9 / 60

The J-chain of immunoglobulin is :

a. Present in IgG

b. Made by T cells

c. Present in IgM

d. Made only by epithelial cells

10 / 60

In acute infection of Hepatitis B, the typical serologic course are:

a. HBcAg

b. HBcAb

c. HBsAg

d. HBsAb

11 / 60

Which cells secreted most cytokine in innate immune:

a. T lymphocyte

b. Plasma cell

c. Macrophage

d. B lymphocyte

12 / 60

The following viral hepatitis is enteric hepatitis?:

a. Hepatitis D

b. Hepatitis A

c. Heepatitis C

d. Hepatitis B

13 / 60

Which of the following immunoglobulin can across placenta with the highest concentration?:

a. IgG2

b. IgG1

c. IgG3

d. IgG4

14 / 60

All of the following are true about antibodies, EXCEPT:

a. They are glycoproteins.

b. They fix complement.

c. They are polypeptide

d. They occur on the surface of B-lymphocyte

15 / 60

The function of LGL cell is:

a. Response to bacteria infection

b. Respose to tumor cells

c. Response to antibody

d. Kill pathogen

16 / 60

Which of the followings are TRUE regarding an Immune response:

a. The T3 complex is signal to the cell's interior to recognize antigen

b. The T4 secrete antibody

c. The T4 support MHC class I in helper reactions

d. The T8 support MHC II in cytotoxic reactions

17 / 60

One principal function of complement is not true:

a. Phagocytize antigens

b. Mediate the release of histamine

c. Lyse target cells

d. Activate perforins

18 / 60

Which of the following bacteriocidal mechanisms is oxygen dependant?:

a. Hydrolytic enzymes

b. Lactoferrin

c. Defensins

d. NADPH oxidation

19 / 60

The function of major histocompatibility complex is:

a. Degrade T4 and T8 polypeptides

b. Bind antibody for cytokine secretion

c. Bind complement for cell lysis

d. Bind epitope for presentation to T-cells

20 / 60

Which of the following is NOT a structural chain in class I MHC?:

a. β2 –microglobin

b. α2

c. α1

d. β1

21 / 60

The vaccine prepared from living and inactivated microbe is considered as?:

a. Antibody

b. Atenuated vaccin

c. Denatured

d. A toxoid

22 / 60

The following statements are true for Antibodies:

a. Contain heavy and light chains

b. Are made from alpha and beta chains

c. Contain no carbohydrate

d. Are carbohydrates

23 / 60

Organ transplantation of human from one place to another is called:

a. Xeno-graft

b. ISO-graft

c. Autograft

d. Allo-graft

24 / 60

The following activity is indicated T cell cytotoxic:

a. MHC-I restricted

b. B cell activation

c. MHC-II restricted

d. Epitope presented to CD4

25 / 60

Immunity acquired after an infection is?:

a. Innate immunity

b. Passive immunity

c. Active immunity

d. Response immunity

26 / 60

The following answer is the best marker for Tc cells?:

a. CD3

b. CD8

c. CD4

d. CD21

27 / 60

The following statement is the basic monomeric immunoglobulin unit, EXCEPT:

a. Able to associate with J- chain to form multimers

b. Same protein type for all antibody classes

c. The receptor is TCR

d. Composed of glycoproptein chains

28 / 60

The factor that stabilize C3 convertase of alternative pathway is :

a. Factor P

b. Factor H

c. DAF

d. Factor I

29 / 60

The following activities are belong to the B-cells :

a. Act as antigen-processing cells

b. Differentiate into plasma cells

c. Receptor antigen monovalent

d. Antibodies response to antigens

30 / 60

The average incubation period of Hepatitis A is?:

a. 30 days

b. 7 days

c. 15 days

d. 60 days

31 / 60

The following immunoglobulin can opsonize antigen during acute phase infection?:

a. IgM

b. IgG

c. IgE IgA

32 / 60

The functional activity of the T-cell:

a. Occurs after recognition of an epitope

b. All answers

c. Can be mediated through cytokines

d. Is related with CD4 or CD8 associated polypeptides

33 / 60

The following answer is NOT true for interleukins?:

a. Produced by T cells

b. Produced by antigen

c. They are not in stock

d. Regulation between cells

34 / 60

Which of the following is NOT a structural chain in class II MHC?:

a. α1

b. β 1

c. α3

d. α2

35 / 60

What distinguishes helper T-cells from cytotoxic T-cells :

a. Helper cells recognize antigen complexed with MHC class I molecules

b. Cytotoxic cells recognize antigen complexed with MHC class I molecules and. Helper cells recognize antigen complexed with MHC class II molecules

c. Cytotoxic cells recognize antigen complexed with MHC class I molecules

d. Helper cells recognize antigen complexed with MHC class II molecules

36 / 60

Which of the following immune cells are effective to destroying intracellular pathogens:

a. Antibodies

b. T cytolytic cells

c. T helper cells

d. B cells

37 / 60

The family of hepatitis C virus is?:

a. Hepanavirus

b. Flavivirus

c. Ribovirus

d. Rotavirus

38 / 60

Papain cleaves what region of immunoglobulin?:

a. Heavy chain

b. Heavy chain and Light chain

c. Light chain

d. Hinge region

39 / 60

Molecule binding to their receptors at high affinity :

a. Antigen

b. All answer

c. Antibody

d. Cytokines

40 / 60

The following statements are true for Class I MHC molecules, EXCEPT :

a. On the APC cells membrane

b. Recognized by the CD8

c. Tc cells kill an infected cells

d. Participated in Th function

41 / 60

The following vaccines is Microbial Fragment Vaccines?:

a. Hepatitis A

b. Clostridium tetani

c. Varicella

d. Polio

42 / 60

Which of the following are true statements:

a. IgA can fix complement

b. IgE lyses allergen

c. IgD provides immunization

d. IgM and IgG can fix complement

43 / 60

Identity the phagocytic cells that have Toll like Receptor on their membrane:

a. Macrophage

b. Neutrophil

c. Eosinophil

d. Basophil

44 / 60

Tumor Necrose Factor (TNF) produce by:

a. Macrophage and Tc

b. Neutrophil

c. Tc

d. Macrophage

45 / 60

The following cells are cells mediated immunity in adaptive immune response?:

a. All answers

b. T cells

c. B cells

d. Tc cells

46 / 60

All of the following are true with respect to IgG antibodies, EXCEPT:

a. They mediate allergic reaction

b. They occur on the surface of B lymphocytes

c. They are glycoproteins

d. They fix complement

47 / 60

Class II MHC are :

a. Used to participate in cytotoxic function

b. Not able to carry an antigen fragment

c. Used to kill by cytotoxic T-cells

d. Recognized by the CD4 protein

48 / 60

All of the following statements are true for the diagnosis of HBV infection, EXCEPT?:

a. Bilirubin

b. Glucose test

c. Liver enzyme

d. Serological HBV

49 / 60

When hepatitis vaccin start to use since year?:

a. 2002

b. 1960

c. 199000%

d. 1985

50 / 60

In the complement system, the classic pathway initiates by the complement :

a. C5

b. C1qrs

c. MBL

d. C4

51 / 60

In the alternative pathway of the complement system, the factors below are useful to prevent the generation of C3 convertase :

a. Factor P

b. C1-INH

c. Factor F

d. C3-BP

52 / 60

In chronic infection of hepatitis B, the antibody persists in the whole life is?:

a. HBcAb

b. HBsAg

c. HBcAg

d. HBsAb

53 / 60

Hyper variability regions are present in:

a. Light chain only

b. Heavy chain only

c. Heavy and light

d. Dark chain

54 / 60

All of the following are the type RNA virus, EXCEPT?:

a. Hepatitis E

b. Hepatitis B

c. Hepatitis A

d. Hepatitis C

55 / 60

Cell mediated immunity in adaptive immune is carried out by?:

a. B cells

b. Antigen

c. T cells

d. Antibody

56 / 60

The immunoglobulin Joining chain (J-chain) is:

a. Produced by mast cells

b. Associated with IgM and IgG

c. Produced by T-Cells

d. Associated with IgM and IgA

57 / 60

The first screening test to detect HBV infection is?:

a. HBcAb

b. HBsAb

c. HBsAg

d. HBcAg

58 / 60

The initial complement component that is bound by complement-fixing antibodies is:

a. C5a

b. C3b

c. C1s

d. C1q

59 / 60

The following vaccines is used after exposure?:

a. Varicella

b. TB

c. Tetanus

d. Hypogammaglobulinemia

60 / 60

The following statement are for adaptive immune response, EXCEPT :

a. Is mediated by the humoral and cellular of the immune

b. Can be facilitated through T-cells

c. Can be facilitated through macrophage cells

d. Can be facilitated by antibodies

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