Immunology Test

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Immunology Test

1 / 60

The answer below is/are artificial active immunization?:

a. Attenuated organisms

b. Killed organisms and Attenuated organisms

c. Killed organisms

d. Exposure to the infections

2 / 60

Which cell is T helper:

a. CD15

b. CD4

c. CD8

d. CD14

3 / 60

Which of the following statements about leukocyte function is false?:

a. Neutrophils phagocytose pathogens .

b. Eosinophils kill parasites

c. Eosinophils release histamine .

d. Leukocytes are cells of the immune response.

4 / 60

All of the following are true, EXCEPT :

a. The variable regions contain the antigen recognition site

b. The class of an immunoglobulin is determined by its heavy chain

c. An antigenic determinant is a paratope

d. An epitope is a fragment of a macromolecule

5 / 60

Which of the following causes AIDS ?:

a. Bacteria

b. Retrovirus

c. TMV

d. Fungus

6 / 60

The following statement are for adaptive immune response, EXCEPT :

a. Is mediated by the humoral and cellular of the immune

b. Can be facilitated through macrophage cells

c. Can be facilitated through T-cells

d. Can be facilitated by antibodies

7 / 60

The following answer is specific for antigen:

a. Fc region

b. Hinge region

c. Fab region

d. Heavy chain

8 / 60

The major role of the complement C3b is to work in conjunction with:

a. Antibodies to lyse cells antgen

b. MHC for cell recognition

c. T-cell for production of lymphokines

d. Antibodies to opsonize cells

9 / 60

Platelets can produce by those organs:

a. Spleen

b. Liver

c. Thymus

d. Bone marrow

10 / 60

Which of the following components of the innate immune system involves the release of
histamine?:

a. Macrophage

b. Eosinophil

c. Tissue mast cell

d. Neutrophil

11 / 60

Which of these factors can cause hepatitis?:

a. Malfunctioning immune system

b. Viruses

c. All of the above

d. Drugs and alcohol

12 / 60

Pepsin cleaves what region of immunoglobulin?:

a. Heavy chain and Light chain

b. Hinge region

c. Light chain

d. Heavy chain

13 / 60

The following answer is the best marker for Tc cells?:

a. CD3

b. CD21

c. CD4

d. CD8

14 / 60

Which of these cell types can play a primary role in attacking and killing cancer cells?:

a. Mast cell

b. T cell

c. Cytotoxic

d. Platelet

15 / 60

The function of major histocompatibility complex for antigen in the cytosol is:

a. Bind complement for cell lysis

b. Presentation antigen to Th-cells

c. Presentation antigen to Tc-cells

d. Transport protein

16 / 60

One principal function of complement is not true:

a. Activate perforins

b. Lyse target cells

c. Phagocytize antigens

d. Mediate the release of histamine

17 / 60

Which of the following is antiviral:

a. Interferon

b. Hormone

c. Lysozyme

d. Protein

18 / 60

The followings statement are TRUE, EXCEPT:

a. MHC I presented on all cells of the immune

b. MHC I bind antigen and recognized by the Tc

c. MHC II bind antigen and recognized by the Th

d. MHC II carrying antigen presented to Tc

19 / 60

The first immunoglobulin secreted by B cells to make up memory cells is?:

a. IgM

b. IgG

c. IgD

d. IgA

20 / 60

Which organ does hepatitis affect?:

a. Heart

b. Brain

c. Liver

d. Kidneys

21 / 60

What is the term used to describe white blood cells migrating toward bacteria? :

a. Zeiosis

b. Chemotaxis

c. Phagocytosis

d. Phototaxis

22 / 60

Which of the following statements about HBV is NOT correct?:

a. Parenteral route

b. Hepato carcinoma

c. RNA virus

d. Can replicate

23 / 60

Which lymphocyte are Large Granular Lymphocytes?:

a. B cells

b. Macropages

c. NK cells

d. T cells

24 / 60

Which of the following immunoglobulin is first synthesized in an immune system to response
an pathogen?:

a. IgG

b. IgE

c. IgA

d. IgM

25 / 60

The tests below show that patient is already vaccinated against HBV?:

a. HBcAb negative

b. HBsAb positive

c. All answers

d. HBsAg negative

26 / 60

Which part of antibody lack of constant domain:

a. CH

b. CL and CH

c. CL

d. VL

27 / 60

Skin is a________ barrier:

a. Physiological

b. Phagocytic

c. Anatomical

d. Inflammatory

28 / 60

Complement Deficiencies of C5, C6, C7, C8 and C9 can causes :

a. Lack of opsonisation

b. Anaphylaxia

c. Susceptibility to pyogenic bacterial infections

d. Inability to attack the Gram-negative bacteria

29 / 60

Biological effect of Complement C2b is:

a. Opsonisation

b. Anaphylaxis

c. Phagocytosis

d. Edema

30 / 60

In the alternative pathway of the complement system, the factors below are useful to stabilise the generation of C3 convertase :

a. C3-BP

b. C1-INH

c. Factor P

d. Factor F

31 / 60

The following organs do not affect by hepatitis virus, EXCEPT:

a. Kidneys

b. Heart

c. Liver

d. Brain

32 / 60

What distinguishes helper T-cells from cytotoxic T-cells:

a. Tc recognize antigen with MHC I

b. Th recognize antigen with MHC I

c. Tc recognize antigen with MHC I and Th recognize antigen with MHC II

d. Th recognize antigen with MHC II

33 / 60

Class II MHC are :

a. Used to participate in cytotoxic function

b. Recognized by the CD4 protein

c. Not able to carry an antigen fragment

d. Used to kill by cytotoxic T-cells

34 / 60

The following statement are for Target cell lysis and destruction, EXCEPT:

a. Complement binding to IgE which have bound to epitopes on the cell surface

b. Complement binding to IgG and IgM which have bound to epitopes on the target cell

c. Perforin released from antigen-specific cytotoxic T-cells

d. Cytotoxic T-cells recognizing specific epitopes on the target cell surface

35 / 60

Which of the followings are TRUE regarding an Immune response:

a. The T8 support MHC II in cytotoxic reactions

b. The T3 complex is signal to the cell's interior to recognize antigen

c. The T4 secrete antibody

d. The T4 support MHC class I in helper reactions

36 / 60

What’s a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:

a. Antigen

b. Peptide

c. MHC II molecule

d. Complement

37 / 60

One principal function of the Class I and Class II major histocompatibility complex is to :

a. Present antigen for recognition by the T-cell receptor

b. Mediate immunoglobulin class

c. Stimulate production of interleukins

d. Transduce the signal to the T-cell interior

38 / 60

Which of the following is NOT true of interleukins:

a. They are able to bind antigen with a high level of specificity

b. They are cytokines which can be produced by various cells of the immune system.

c. They are in need of receptors on the target cell in order to mediate their effects.

d. They are hormones which allow one cell to communicate with another cell.

39 / 60

Which among the following is anti-bacterial ?:

a. Lysozyme

b. Protein

c. Hormone

d. Interferon

40 / 60

To stabilise the C3 convertase of the alternative pathway, the factors below are useful :

a. C3-BP

b. Factor F

c. C1-INH

d. Factor P

41 / 60

Name the process a cell such as a neutrophil or a macrophage uses to ingest (eat) its prey.:

a. Chemotaxis

b. Phagocytosis

c. Halitosis

d. Botulism

42 / 60

The variable regions in the light chains participate in:

a. Affinity of the complement receptors.

b. Epitope binding.

c. Fc receptor binding.

d. Interaction of the Fab with cytokines.

43 / 60

The following answers is receptor for complement on immunoglobulins:

a. Heavy chain

b. Fab region

c. Hinge region

d. Fc region

44 / 60

The lectin pathway of the complement is initiated by:

a. MBL

b. C1qrs

c. Factor B

d. C3

45 / 60

Which type of cell destroys body cells that cause by infection?:

a. Memory B cells

b. Cytotoxic T cells

c. Memory T cells

d. Plasma B cells

46 / 60

Which of the following require the Thymus?:

a. B cellsmaturation

b. B cel apoptosis

c. T cells rogenitor

d. T cells maturation

47 / 60

The factor that dissociated the initiation of C1qrs in the classical pathway is:

a. C3-BP

b. Factor F

c. Factor P

d. C1-INH

48 / 60

Which lymphocyte response to HBV infectin?:

a. Tc

b. Macrophage

c. Th

d. B cells

49 / 60

Complements are chemically:

a. Glycogens

b. Proteins

c. Lipoproteins

d. Glycoproteins

50 / 60

Which cells secreted most cytokine in innate immune:

a. T lymphocyte

b. Plasma cell

c. B lymphocyte

d. Macrophage

51 / 60

The following immunoglobulin is used to produe vaccine?:

a. IgA

b. IgG4

c. IgG

d. IgM

52 / 60

The pathway of the complement that can lyse bacteria is:

a. Lectin pathway

b. Classical pathway

c. Alternative pathway

d. Lytic pathway

53 / 60

All of the following are true with respect to IgE molecules, EXCEPT :

a. They will cross the placenta and fix complement)

b. They can effect the release of histamine.

c. They are the principal immunoglobulin class involved in allergic reactions.

d. They are involved in mediating anti-parasitic immune responses

54 / 60

The screening test for HBV infection is?:

a. HBsAg

b. HBcAb

c. HBsAb

d. HBcAg

55 / 60

The cancer of T cells are called?:

a. Extranodal T cell lymphoma

b. All answers

c. Non-Hodgkin lymphoma

d. Hodgkin lymphoma

56 / 60

The first sign of infection is the characteristic appearance of ?:

a. HBsAb

b. HBeAg

c. HBcAb

d. HBsAg

57 / 60

Which of the following are mechanisms for neutrophil phagocytosis:

a. Hydrolytic enzymes

b. Azerophilic granules and defensins

c. Azerophilic granules

d. defensins

58 / 60

All of the following are true with respect to IgM antibodies, EXCEPT :

a. They are glycoproteins

b. They mediate allergic reaction

c. They fix complement

d. They occur on the surface of lymphocytes

59 / 60

The family of hepatitis C virus is?:

a. Flavivirus

b. Hepanavirus

c. Ribovirus

d. Rotavirus

60 / 60

The T3 complex of the T-cell receptor:

a. Binds complement

b. Causes the histamine

c. Mediates Immunoglobulin class switching

d. To transduce a signal to the cell's interior

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