Immunology Test

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Immunology Test

1 / 60

Individuals make up over C4a would be expected to have:

a. Anaphylaxia

b. Liver disease

c. Diabetis

d. Bacteria

2 / 60

All of the following are true with respect to IgE molecules, EXCEPT :

a. They are involved in mediating anti-parasitic immune responses

b. They can effect the release of histamine.

c. They are the principal immunoglobulin class involved in allergic reactions.

d. They will cross the placenta and fix complement)

3 / 60

Which of the following antibody fragments consists of a dimer of the heavy-chain constant
region but lacks the CH1 domains?:

a. F(ab)’2

b. F(ab)

c. Fab

d. Fc

4 / 60

The Complement that produce anaphylactic much more potent is:

a. C4a

b. C5a

c. C3a

d. C2b

5 / 60

Which cell is Granulocyte:

a. Monocyte

b. Basophil

c. Macrophage

d. Lymphocyte

6 / 60

The percentage of TH cell among lymphocytes is?:

a. 23%

b. 46%

c. 19%

d. 7%

7 / 60

The following answer is the function of IgG, EXCEPT :

a. Activate complement

b. Opsonize bacteries

c. Primary response to antigen

d. Cross placenta

8 / 60

All of the following are true with respect to IgM antibodies, EXCEPT :

a. They occur on the surface of lymphocytes

b. They mediate allergic reaction

c. They fix complement

d. They are glycoproteins

9 / 60

Which type of antibody is MOST effective in activating complement?:

a. IgG2

b. IgG3

c. IgG1

d. IgM

10 / 60

The following statements are true for Class III MHC molecules, EXCEPT :

a. Recognized by the CD8

b. On the APC cells membrane

c. Tc cells kill an infected cells

d. Transport protein

11 / 60

The following cells of immune system cam make inflammation:

a. Basophils

b. Mast cells and Basophils

c. Monocytes

d. Mast cells

12 / 60

The following statements are true for Antibodies, EXCEPT :

a. Made of heavy and light chains

b. Extra domain for IgM

c. Receptors for antigens are monovalent

d. Fc receptor for complement

13 / 60

Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:

a. Polio

b. Neisseria meningitides

c. Haemophilus influenzae B

d. Hepatitis B virus

14 / 60

In the alternative pathway of the complement system, the factors below are useful to prevent the generation of C3 convertase :

a. C1-INH

b. Factor F

c. Factor P

d. C3-BP

15 / 60

Tumor Necrose Factor (TNF) produce by:

a. Tc

b. Macrophage and Tc

c. Macrophage

d. Neutrophil

16 / 60

Which immunoglobulin is used to produce vaccine:

a. IgM

b. IgE

c. IgG

d. IgA

17 / 60

HBV infection is characterized by the present of ?:

a. HBcAg

b. HBeAg

c. HBsAg

d. All answers

18 / 60

The following cells are proliferated from myloid progenitor :

a. TH1

b. Lymphocytes

c. Dendritic cells

d. B cells

19 / 60

Intracellular pathogen is presented to the Tc by:

a. MHC I

b. MHC II

c. Lymphocytes

d. TH

20 / 60

The major role of the complement C3b is to work in conjunction with:

a. Antibodies to opsonize cells

b. T-cell for production of lymphokines

c. Antibodies to lyse cells antgen

d. MHC for cell recognition

21 / 60

Class II MHC are :

a. Recognized by the CD4 protein

b. Not able to carry an antigen fragment

c. Used to participate in cytotoxic function

d. Used to kill by cytotoxic T-cells

22 / 60

In chronic infection of hepatitis B, the antibody persists in the whole life is?:

a. HBcAg

b. HBsAb

c. HBcAb

d. HBsAg

23 / 60

All of the following are true of antigen, EXCEPT:

a. They contain paratopes

b. They will react with antibodies.

c. They contain epitopes.

d. They contain antigenic determinants.

24 / 60

All of the following are the type RNA virus, EXCEPT?:

a. Hepatitis A

b. Hepatitis E

c. Hepatitis C

d. Hepatitis B

25 / 60

The T-cell receptor is:

a. Bivalent

b. Recognized antibody

c. Recognized antigen fragments

d. Secreted by the T-cell

26 / 60

The basic monomeric Immunoglobulin unit is:

a. One of five major classes

b. Four polypeptide chains

c. Four polypeptide chains and One of five major classes

d. Synthesized by a T-cell

27 / 60

The T3 complex of the T-cell receptor :

a. Causes the histamine

b. To transduce a signal to the cell's interior binding to antigen

c. Binds complement

d. Mediates Immunoglobulin class switching

28 / 60

The function of MHC class II is:

a. Recognized by the CD8

b. Participated in the presentation of Ag

c. Recognized by CD4

d. Unable to carry antigen fragment

29 / 60

The cells that have azerophilic granule to facilitate phagocytosis is:

a. Neutrophils

b. Mast cells

c. Monocytes

d. Basophils

30 / 60

The rabic vaccin is used to?:

a. Prevent rabie infection

b. Cure rabie infection

c. Cure tetanus infection

d. Prevent tetanus infection

31 / 60

The screening test for HBV infection is?:

a. HBcAb

b. HBsAg

c. HBsAb

d. HBcAg

32 / 60

The following vaccines is not used in United State?:

a. Hepatitis A

b. Varicella

c. Tuberculsis

d. Polio

33 / 60

The following answer is NOT true for interleukins?:

a. Regulation between cells

b. Produced by antigen

c. They are not in stock

d. Produced by T cells

34 / 60

What distinguishes helper T-cells from cytotoxic T-cells:

a. Th recognize antigen with MHC II

b. Tc recognize antigen with MHC I

c. Tc recognize antigen with MHC I and Th recognize antigen with MHC II

d. Th recognize antigen with MHC I

35 / 60

Superantigens presented to T cells by :

a. Mast cell

b. Monocyte

c. B cell

d. APC

36 / 60

The following statement are MOST closely related to each, EXCEPT:

a. Antigen

b. Antibody

c. Allergen

d. Epitope

37 / 60

The function of LGL cell is:

a. Kill pathogen

b. Response to antibody

c. Response to bacteria infection

d. Respose to tumor cells

38 / 60

Each of the following is a characteristic of antibodies, EXCEPT :

a. They combine specifically with antigen

b. They are proteins with variable and constant regions

c. They are only secreted by T-cells

d. They contain carbohydrates

39 / 60

The followings statement are TRUE, EXCEPT :

a. MHC Class II carrying antigen presented to cytotoxic T cells

b. MHC Class II bind antigen and are recognized by the T-cell receptor and the CD4

c. MHC Class 1 bind antigen fragments and are recognized by the Tc-cell receptor

d. MHC Class I generally occur on all cells of the immune system

40 / 60

The pathway of the complement that can lyse bacteria is:

a. Lytic pathway

b. Lectin pathway

c. Classical pathway

d. Alternative pathway

41 / 60

The Complement that gives Anaphylotoxin much potent is:

a. C2b

b. C3a

c. C4a

d. C5a

42 / 60

All of the following are function of IgG, EXCEPT :

a. Primary response to antigen

b. Opsonize bacteries

c. Activate complement

d. Cross placenta

43 / 60

Immunoglobulins are chemically:

a. Glycogens

b. Glycoproteins

c. Glycolipids

d. D. Lipo-proteins

44 / 60

How many percentage of chronic HBV infection can lead to Cirrhosis?:

a. 25%

b. 50%

c. 10%

d. 15%

45 / 60

The primairy response of antibody to the HBV is?:

a. IgM

b. IgG

c. IgA

d. IgE

46 / 60

Which type of cell destroys body cells that cause by infection?:

a. Cytotoxic T cells

b. Memory T cells

c. Plasma B cells

d. Memory B cells

47 / 60

The component of immune system that can cause fever is :

a. Complement

b. Immunoglobulin

c. Macrophage

d. T lymphocytes

48 / 60

The disease below can cause allergic reaction:

a. Thalassemia

b. Asthma

c. Cancer

d. Hepatitis

49 / 60

T-cell receptors or antibodies react with antigens:

a. Because both 'have light chain and heavy chain polypeptides

b. Because both are made by lymphocytes

c. Cause histamine release

d. Because they have specific receptors for antigen

50 / 60

All of the following are true, EXCEPT:

a. IgG antibody is pentavalent

b. IgM antibody is pentamer

c. An epitope is a portion of an antigen

d. The variable contain the antigen recognition site

51 / 60

The J-chain is :

a. Made only by epithelial cells

b. Facilitates secretion of pentameric lgM

c. For immunoglobulin multimer formation and Facilitates secretion of pentameric lgM

d. For immunoglobulin multimer formation

52 / 60

How many serotypes of HCV in the world?:

a. 2

b. Many

c. 6

d. 4

53 / 60

In the complement system, the classic pathway initiates by the complement :

a. MBL

b. C5

c. C4

d. C1qrs

54 / 60

The following statements are true for the antigenic determinant :

a. Small part of the antigen

b. Is the combining site of an antibody

c. Is paratope

d. Is paratope and Small part of the antigen

55 / 60

Biological effect of Complement C4a is regulated by:

a. Factors H & I

b. C3-INA

c. C4-BP

d. Factor I

56 / 60

The Biological Effects of C3b is :

a. Anaphylaxia

b. Phagocyte activation

c. Susceptibility to bacterial infections

d. Lack of opsonisation

57 / 60

Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis C virus

b. Hepatitis D virus

c. Hepatitis B virus

d. Hepatitis A virus

58 / 60

The functional activity of the T-cell:

a. Can be mediated through cytokines

b. Is related with CD4 or CD8 associated polypeptides

c. Occurs after recognition of an epitope

d. Is related with CD4 or CD8 associated polypeptides, Occurs after recognition of an epitope, Can be mediated through cytokines

59 / 60

The following statements are true for Class II MHC molecules, EXCEPT :

a. Recognized by the CD4

b. Able to carry an antigen fragment

c. Used to participate in Th function

d. Presented antigen to Tc cells

60 / 60

The vaccine prepared from living and inactivated microbe is considered as?:

a. Antibody

b. A toxoid

c. Denatured

d. Atenuated vaccin

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