Immunology Test – testnisset.com

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Immunology Test

1 / 60

The major role of the complement C3b is to work in conjunction with:

a. Antibodies to lyse cells antgen

b. Antibodies to opsonize cells

c. MHC for cell recognition

d. T-cell for production of lymphokines

2 / 60

The Natural Killer T Cells work in the immune system :

a. Innate immunity

b. Adaptive immunity

c. Adaptive immunity and Innate immunity

d. Link between Adaptive and Innate immune

3 / 60

The drug to cure post exposure of HBV is?:

a. IgM

b. IgA

c. IgG

d. IgE

4 / 60

The major histocompatibility complex proteins function to:

a. Bind antibody for lymphokine production

b. Bind antigen for presentation to T-cells

c. Bind complement for cell lysis

d. Degrade T4 and T8 polypeptides

5 / 60

All of the following are true, EXCEPT :

a. An antigenic determinant is a paratope

b. The class of an immunoglobulin is determined by its heavy chain

c. An epitope is a fragment of a macromolecule

d. The variable regions contain the antigen recognition site

6 / 60

The two types of lymphocytes are ?:

a. Platelet and Erythrocyte

b. T and B cells

c. Erythrocyte and T cells

d. Platelet and B cells

7 / 60

The percentage of TH cell among lymphocytes is?:

a. 46%

b. 19%

c. 7%

d. 23%

8 / 60

Which of the following immune cells/molecules are most effective to destroying intracellular
pthogens ?:

a. B cells

b. Plasma cells

c. T cytotoxic cells

d. T helper cells

9 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgA

b. IgM

c. IgE

d. IgG

10 / 60

Which of the following immunoglobulins is present normally in plasma at the highest concentration?:

a. IgG

b. IgE

c. IgM

d. IgA

11 / 60

Thymus growth occurs up to:

a. 30 years

b. 12 years

c. 17 years

d. 5 years

12 / 60

All of the following are true of antigen, EXCEPT:

a. They will react with antibodies.

b. They contain paratopes

c. They contain epitopes.

d. They contain antigenic determinants.

13 / 60

These blood cells have memory after pathogens infection, EXCEPT? TH cells?:

a. Macrophages

b. Tc cells

c. B cells

14 / 60

T-cell receptors or antibodies react with antigens:

a. Cause histamine release

b. Because they have specific receptors for antigen

c. Because both ‘have light chain and heavy chain polypeptides

d. Because both are made by lymphocytes

15 / 60

Each of the following statement is a characteristic of antibodies, EXCEPT:

a. They are phagocytes

b. They have four glycoprotein chains

c. They contain variable region

d. They have specific receptor for antigen

16 / 60

The function of major histocompatibility complex is:

a. Bind antibody for cytokine secretion

b. Bind epitope for presentation to T-cells

c. Degrade T4 and T8 polypeptides

d. Bind complement for cell lysis

17 / 60

Which of the following is NOT a structural chain in class I MHC?:

a. β1

b. α2

c. β2 –microglobin

d. α1

18 / 60

Which of the following immunoglobulin is first synthesized in an immune system to response
an pathogen?:

a. IgE

b. IgM

c. IgA

d. IgG

19 / 60

Which of the following components of the adaptive immune system secretes immunoglobulin
(Ig)?:

a. Resting lymphocytes (B cell, T cell)

b. CD8+ cytotoxic T cell (CTL)

c. Activated B cell (plasma cell)

d. CD4+ activated T cell

20 / 60

The CD marker of B cells are?:

a. CD19 and CD21

b. CD16 and CD56

c. CD3 and CD54

d. CD3 and CD8

21 / 60

Which of the following binds to an Fc receptor on mast cells and basophils?:

a. IgE:

b. IgM

c. IgG

d. IgA

22 / 60

The following statements are true for Antibodies, EXCEPT:

a. Made of heavy and light chains

b. Non immunogen

c. They have hypervariable region

d. Composed of variable and constant regions

23 / 60

The following answers is receptor for complement on immunoglobulins:

a. Fc region

b. Fab region

c. Hinge region

d. Heavy chain

24 / 60

One principal function of complement is to:

a. Mediate the release of histamine

b. Bind antibodies attached to cell surfaces and to lyse these cells

c. Inactivate perforins

d. Phagocytize antigens

25 / 60

The function of Natural Killer cell is:

a. Response to antibody

b. Response to bacteria infection

c. Kill pathogen

d. Damaged the target cell membrane

26 / 60

Where is the variable region of Immunoglobulin?:

a. CL

b. CH2

c. VL

d. CH3

27 / 60

To stabilise the C3 convertase of the alternative pathway, the factors below are useful :

a. C1-INH

b. Factor F

c. C3-BP

d. Factor P

28 / 60

Biological effect of Complement C2b is:

a. Anaphylaxis

b. Opsonisation

c. Edema

d. Phagocytosis

29 / 60

The following activity is indicated T cell cytotoxic:

a. B cell activation

b. MHC-II restricted

c. MHC-I restricted

d. Epitope presented to CD4

30 / 60

The first screening test to detect HBV infection is?:

a. HBcAb

b. HBsAg

c. HBcAg

d. HBsAb

31 / 60

The answers below are characteristic of antigen, EXCEPT:

a. Are toxin

b. Contain epitopes

c. React with antibody

d. Contain paratopes

32 / 60

The following viral hepatitis is enteric hepatitis?:

a. Hepatitis A

b. Hepatitis D

c. Hepatitis B

d. Heepatitis C

33 / 60

Superantigens presented to T cells by :

a. B cell

b. APC

c. Monocyte

d. Mast cell

34 / 60

The following statement are MOST closely related to each, EXCEPT:

a. Antibody

b. Antigen

c. Epitope

d. Allergen

35 / 60

The class of an immunoglobulin is determined by:

a. Class I and II MHC

b. The antigen

c. The light chain

d. The heavy chain

36 / 60

Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:

a. Neisseria meningitides

b. Hepatitis B virus

c. Haemophilus influenzae B

d. Polio

37 / 60

Which of the following are true statements:

a. IgE lyses allergen

b. IgM and IgG can fix complement

c. IgA can fix complement

d. IgD provides immunization

38 / 60

Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Hepatitis B

b. Rabies

c. Polio

d. Pertussis

39 / 60

The following molecules can activate B cells to secrete antibody, EXCEPT:

a. Antigen

b. Allergen

c. Antigenic determinant

d. Hapten

40 / 60

Which properties do the T-cell receptor and the antibody share in common:

a. Both have constant regions

b. Both are polypeptide chains

c. Both recognize antigen fragments

d. Both are able to fix complement

41 / 60

Which of the following is a β structural chain in class I MHC?:

a. α2

b. α1

c. β1

d. β2 –microglobin

42 / 60

The following answers are true for phagocytosis, EXCEPT:

a. NK cell

b. Opsonisation

c. Ingest pathogen

d. Supported by complement

43 / 60

The chronic HCV infection develop hepatocellular carcinoma in the rate of?:

a. 10%

b. 5%

c. 50%

d. 20%

44 / 60

All of the following are true about antibodies, EXCEPT:

a. They are a single amino acid sequence

b. They are glycoproteins.

c. They fix complement.

d. They occur on the surface of B-lymphocyte

45 / 60

What’s a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:

a. Peptide

b. Complement

c. Antigen

d. MHC II molecule

46 / 60

These organ is primary lymphoid organ of human?:

a. Spleen

b. Tonsil

c. Thymus

d. Lymph node

47 / 60

The following cells of immune system cam make inflammation:

a. Basophils

b. Mast cells and Basophils

c. Mast cells

d. Monocytes

48 / 60

Which of the following is NOT a major feature (characteristic) of the adaptive immune
system?:

a. Memory

b. Specificity

c. Diversity

d. Improvement

49 / 60

The following statements are true for IgE, EXCEPT:

a. They produce allergic reaction

b. Can cross the placental barrier

c. The least immunoglobulin in the plasma

d. They bind to mast cells

50 / 60

Papain cleaves what region of immunoglobulin?:

a. Hinge region

b. Light chain

c. Heavy chain and Light chain

d. Heavy chain

51 / 60

Which cell is Granulocyte:

a. Macrophage

b. Lymphocyte

c. Monocyte

d. Basophil

52 / 60

All of the following are function of IgG, EXCEPT :

a. Activate complement

b. Primary response to antigen

c. Opsonize bacteries

d. Cross placenta

53 / 60

Which antigen is direct presented to B cell?:

a. T- dependent antigen

b. Self- antigen

c. Non self- antigen

d. T- Independent antigen

54 / 60

Variable regions of immunoglobulin are:

a. N-terminal of heavy chains

b. Able to fix complement

c. Specific recognition of antigen

d. C-terminal of heavy chains

55 / 60

Histamine is secreted by:

a. Mast cells

b. White blood cells

c. Red blood cells

d. Epithelial cell

56 / 60

Which lymphocyte response to HBV infectin?:

a. Macrophage

b. B cells

c. Tc

d. Th

57 / 60

The rabic vaccin is used to?:

a. Prevent tetanus infection

b. Cure rabie infection

c. Cure tetanus infection

d. Prevent rabie infection

58 / 60

The most infection chronic and acute HBV is in?:

a. Female

b. Children

c. Male

d. Adult

59 / 60

The cells that have azerophilic granule to facilitate phagocytosis is:

a. Basophils

b. Mast cells

c. Monocytes

d. Neutrophils

60 / 60

The following answers are function of B cell, EXCEPT?:

a. Complement cascade

b. Antibody secretion

c. Memory B cells

d. APC

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