Immunology Test

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Immunology Test

1 / 60

All of the following are true about antibodies, EXCEPT:

a. They are polypeptide

b. They are glycoproteins.

c. They fix complement.

d. They occur on the surface of B-lymphocyte

2 / 60

The following tests show that patient has a chronic HBV infection, EXCEPT?:

a. HBsAb

b. HBcAb

c. HBsAg

d. HBcAg

3 / 60

To stabilise the C3 convertase of the alternative pathway, the factors below are useful :

a. Factor F

b. C1-INH

c. C3-BP

d. Factor P

4 / 60

The Live Attenuated Vaccines are used for the diseases below?:

a. All answers

b. Hepatitis A

c. Varicella zoster

d. Measles

5 / 60

The natural passive immunity are characterized by?:

a. Placental transfert

b. Immunoglobulins

c. Kill vaccin Immune cell

6 / 60

The variable regions in the heavy chains participate in:

a. Antigen receptor

b. Complement receptor

c. Cytokine receptor

d. Cellular receptor

7 / 60

Individuals unable to make the C4b would be expected to have frequent infections of the :

a. Thalassemia

b. Bacteria

c. Diabetis

d. Liver disease

8 / 60

The TH cells produced cytokines to response the viral infection?:

a. Interferon

b. Chimokine

c. IL-2

d. Tumor necrose factor

9 / 60

Light chains are :

a. Complement fixation

b. Have only a constant region

c. Specific for each class of antibody

d. Reactive with antigen

10 / 60

The functional activity of the T-cell:

a. Occurs after recognition of an epitope

b. Is related with CD4 or CD8 associated polypeptides, Occurs after recognition of an epitope, Can be mediated through cytokines

c. Can be mediated through cytokines

d. Is related with CD4 or CD8 associated polypeptides

11 / 60

The following viral hepatitis is enteric hepatitis?:

a. Hepatitis A

b. Hepatitis D

c. Heepatitis C

d. Hepatitis B

12 / 60

Molecule binding to their receptors at high affinity :

a. Antigen

b. Antibody

c. Cytokines

d. All answer

13 / 60

The function of Natural Killer cell is:

a. Response to antibody

b. Response to bacteria infection

c. Kill pathogen

d. Damaged the target cell membrane

14 / 60

The T3 complex of the T-cell receptor :

a. To transduce a signal to the cell's interior binding to antigen

b. Causes the histamine

c. Binds complement

d. Mediates Immunoglobulin class switching

15 / 60

Which of the following statements about HBV is NOT correct?:

a. Hepato carcinoma

b. Parenteral route

c. RNA virus

d. Can replicate

16 / 60

Which lymphocyte response to HBV infectin?:

a. Macrophage

b. Th

c. Tc

d. B cells

17 / 60

Which of the following statements about leukocyte function is false?:

a. Eosinophils kill parasites

b. Neutrophils phagocytose pathogens .

c. Eosinophils release histamine .

d. Leukocytes are cells of the immune response.

18 / 60

The functional activity of the T-cell:

a. Is related with CD4 or CD8 associated polypeptides

b. Occurs after recognition of an epitope

c. Can be mediated through cytokines

d. All answers

19 / 60

Which type of cell destroys body cells that cause by infection?:

a. Memory B cells

b. Cytotoxic T cells

c. Memory T cells

d. Plasma B cells

20 / 60

Which of the following components of the innate immune system involves the release of
histamine?:

a. Tissue mast cell

b. Macrophage

c. Eosinophil

d. Neutrophil

21 / 60

Killed Whole-Organism is used to prepare vaccines below, EXCEPT?:

a. Hepatitis B

b. Polio

c. Pertussis

d. Rabies

22 / 60

Biological effect of Complement C5a is:

a. Neutrophil activation

b. Inflammation

c. Phagocytosis

d. Opsonisation

23 / 60

The CD marker of B cells are?:

a. CD19 and CD21

b. CD3 and CD8

c. CD3 and CD54

d. CD16 and CD56

24 / 60

Which of the following immunoglobulin is first synthesized in an immune system to response
an pathogen?:

a. IgG

b. IgA

c. IgE

d. IgM

25 / 60

The following molecules can activate B cells to secrete antibody, EXCEPT:

a. Antigenic determinant

b. Allergen

c. Antigen

d. Hapten

26 / 60

Which of the following antibody fragments consists of a dimer of the heavy-chain constant
region but lacks the CH1 domains?:

a. F(ab)’2

b. Fab

c. Fc

d. F(ab)

27 / 60

All of the following are a part of innate immune respond, EXCEPT :

a. Natural Killer cells

b. T cells secrete antibody

c. Pathways of complement activation

d. Macrophage secrete cytokines

28 / 60

The tests below show that patient is susceptible to an HBV infection?:

a. HBsAb negative

b. HBsAg negative

c. HBcAb negative

d. All answers

29 / 60

The function of cytokines are :

a. Production of complement

b. Regulation the immune cells

c. Bind to MHC class I

d. Specifically recognize antigens

30 / 60

The following activities are belong to the B-cells :

a. Receptor antigen monovalent

b. Act as antigen-processing cells

c. Differentiate into plasma cells

d. Antibodies response to antigens

31 / 60

How many serotypes of HCV in the world?:

a. 2

b. 4

c. 6

d. Many

32 / 60

These cytokines secreted by T helper cell?:

a. TNF-α

b. IL-2

c. Chimokine

d. Interferon

33 / 60

All of the following are true of antigen, EXCEPT:

a. They will react with antibodies.

b. They contain paratopes

c. They contain epitopes.

d. They contain antigenic determinants.

34 / 60

The following cells of immune system cam make IgE:

a. Mast cells

b. Mast cells and Eosinophils

c. Eosinophils

d. Monocytes

35 / 60

The following immunoglobulin(s) become monomer when they attaché antigen :

a. IgE

b. IgM

c. IgG

d. IgA

36 / 60

Class II MHC molecule works for?:

a. An antigen fragment

b. B cell activation

c. Tc function

d. T helper function

37 / 60

Which of the following components of the adaptive immune system secretes immunoglobulin
(Ig)?:

a. Resting lymphocytes (B cell, T cell)

b. CD8+ cytotoxic T cell (CTL)

c. Activated B cell (plasma cell)

d. CD4+ activated T cell

38 / 60

The following statement is for MHC Class I:

a. Recognized by the CD8 protein

b. Used to kill by cytotoxic T-cells

c. Not able to carry an antigen fragment

d. Participated in helper function

39 / 60

Which of the following virus is NOT transmitted through the parenteral route?:

a. Hepatitis C

b. Hepatitis B

c. Hepatitis D

d. Hepatitis A

40 / 60

Which of the following hepatitis viruses is RNA virus?:

a. Hepatitis B virus

b. Hepatitis C virus

c. Hepatitis D virus

d. Hepatitis A virus

41 / 60

Complement Deficiencies of C5, C6, C7, C8 and C9 can causes :

a. Inability to attack the Gram-negative bacteria

b. Lack of opsonisation

c. Anaphylaxia

d. Susceptibility to pyogenic bacterial infections

42 / 60

How many receptors for antigen on the surface of T lymphocyte:

a. 4

b. 2

c. 10

d. 1

43 / 60

The immunoglobulin Joining chain (J-chain) is:

a. Produced by mast cells

b. Associated with IgM and IgA

c. Associated with IgM and IgG

d. Produced by T-Cells

44 / 60

The following characcteristic is common for T and b cells?:

a. Polypeptide chains

b. have constant regions

c. able to fix complement

d. Recognize antigen

45 / 60

Which of the following represent immune system dysfunctions:

a. Severe immunodeficiency

b. Mast cells release histamine

c. Facilitated by antibodies

d. T cells proliferation

46 / 60

Which of the following immune cells/molecules are most effective to destroying intracellular
pthogens ?:

a. B cells

b. T cytotoxic cells

c. Plasma cells

d. T helper cells

47 / 60

The disease below can cause by autoimmune:

a. SLE

b. Cancer

c. Hepatitis

d. Thalassemia

48 / 60

The following statement is the basic monomeric immunoglobulin unit, EXCEPT:

a. The receptor is TCR

b. Composed of glycoproptein chains

c. Able to associate with J- chain to form multimers

d. Same protein type for all antibody classes

49 / 60

The following statement are for adaptive immune response, EXCEPT :

a. Is mediated by the humoral and cellular of the immune

b. Can be facilitated through macrophage cells

c. Can be facilitated by antibodies

d. Can be facilitated through T-cells

50 / 60

The following diseases can be prevented by vaccination?:

a. Hepatitis D and C

b. Hepatitis C and E

c. Hepatitis B and C

d. Hepatitis A and B

51 / 60

The following statements are true for Antibodies, EXCEPT :

a. Extra domain for IgM

b. Made of heavy and light chains

c. Receptors for antigens are monovalent

d. Fc receptor for complement

52 / 60

The T-cell receptor is:

a. Recognized antigen fragments

b. Secreted by the T-cell

c. Recognized antibody

d. Bivalent

53 / 60

Immunity acquired after an infection is?:

a. Active immunity

b. Innate immunity

c. Passive immunity

d. Response immunity

54 / 60

The variable regions in the light chains participate in:

a. Interaction of the Fab with cytokines.

b. Affinity of the complement receptors.

c. Epitope binding.

d. Fc receptor binding.

55 / 60

Regulatory T cells (Treg cells), formerly known as ?:

a. Suppressor T cells

b. Natural T reg

c. CD4+ T reg

d. Adaptive T reg

56 / 60

The following answers are true for phagocytosis, EXCEPT:

a. Ingest pathogen

b. Opsonisation

c. NK cell

d. Supported by complement

57 / 60

Which of the following technic is the best method to detect early infection of hepatitis?:

a. Agglutination

b. ELISA

c. PCR

d. RIA

58 / 60

Organ transplantation of human from one place to another is called:

a. ISO-graft

b. Xeno-graft

c. Allo-graft

d. Autograft

59 / 60

The Cytotoxic T cells kill the cells/molecules below:

a. Extracellular antigen

b. Infected cells

c. Intracellular antigen

d. Bacteria

60 / 60

The Biological Effects of C3b is :

a. Phagocyte activation

b. Anaphylaxia

c. Lack of opsonisation

d. Susceptibility to bacterial infections

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