/52 2900 Microbiologie Preparation (Dr. Aim Sothea) 1 / 52 1) A 55-year-old man came to IPD complaining of weakness, malaise, and cough. He has history of smoking and social drinking. General condition upon admission was moderate: axillar temperature of 38 °C, respiratory rate of 21/min, SpO2 of 92%, heart rate at 90 beats/min, and blood pressure of 130/70 mm Hg. Bilateral pneumonia was suspected on chest-x ray. Culture of sputum showed coagulase positive, Gram positive cocci. Which of the following microorganism causes for this condition? a. Clostridium perfringens b. Staphylococcus aureus c. Streptococcus pneumonia d. Streptococcus pyogenes 2 / 52 2) A 6-year-old boy developed an erythematous rash around his face and arms. Swollen lymph nodes around the infection were reported on the physical examination but no other abnormality. A gram- positive and coagulase positive cocci were identified. What is most likely pathogen for above condition? a. Streptococcus agalactiae b. Staphylococcus aureus c. Staphylococcus saprophyticus d. Streptococcus pyogens 3 / 52 3) Streptococcus viridans can be differentiated from other haemolytic Streptococci on the basis of its resistance to a. Novobiocin b. Optochin c. Penicillin d. Bacitracin 4 / 52 4) 60-man is hospitalized for pneumonia and urine catheter is placed. Patient feels better after 2 days, however he has dysuria and urgency. A urine culture reveals gramm+ in pairs and chain. Antibiogram is resistant to vancomycin. What is true about the pathogen? a. Grow in 6.5% NaCl b. Does not grow in 6.5% NaCl c. Is catalase positive d. Show β-hemolysis in blood agar 5 / 52 5) What is major virulence factor for Streptococcus pneumoniae uses to evade the host’s immune response? a. PspA (protective antigen), b. Pneumolysin c. LytA, B, and C autolysins d. Capsular polysaccharide 6 / 52 6) A 17-year female was admitted complaining about a fever of 39.3oC and vomiting. She started her menstrual period 4 days before she became ill. On the next day of admission, she had continued fever, vomiting and loose stools. She was hypotensive of SBP of 78 & DBP 54 mmHg with a heart rate of 120 beats per min. Physical exam found most prominent erythematous rash on her trunk. Cultures were obtained from vaginal specimen show catalase positive, Gram positive cocci of staphylococcus colonies. Which cytokines are responsible for systemic shock syndrome? a. IL-2 and IL-15 b. IL-10 and TGF c. TNFa and IL-1 d. IL-12 and IL-13 7 / 52 7) During one week, a 7-year boy develops pustules on his face. Then, some of the pustules break, forming shallow erosions in appearance of a honey-colored crust. Next, new lesions form around the crust. The boy’s¬ father has similar lesions after one week of the son’s illness. The Gram stain from a skin pustule showed gram positive in grape-like clusters. The colonies were catalase positive. What is the most likely microorganism? a. Staph saprophyticus b. Staph hominis c. Staph aureus d. Staph epidermidis 8 / 52 8) Before dental procedure Ampicillin is given to prevent bacterial sub-acute endocarditis in high- risk person. What is most likely pathogen for this condition? a. Streptococcus spp. b. Streptococcus sanguinis c. Streptococcus agalactiae d. Streptococcus pneumoniae 9 / 52 9) A 19-y sexually active woman came to OPD having dysuria and pain when urinating. Urine culture reveals Gram positive, Coagulase negative and novobiocin negative cocci. What pathogen is most likely causing the presenting problem? a. Staph aureus b. Staph hominis c. Staph saprophyticus d. Staph epidermidis 10 / 52 10) Staphylococcus spp. and Streptococcus spp. are a. Gram negative cocci b. Gram negative bacilli c. Gram positive bacilli d. Gram positive cocci 11 / 52 11) A 39-y patient is on Central Venous Perfusion line in an ICU. Culture around the line grows Gramm positive, Coagulase negative cocci in cluster. Which of the following is most likely pathogen for the above description? a. Staph aureus b. Staph hominis c. Staph saprophyticus d. Staph epidermidis 12 / 52 12) A 25-y woman came to ER having 5-hour of fever, rash, and altered mental status. Her BP is low (76/58) and HR is fast. After physical exam, a used tampon is removed from genital tract. Culture of vaginal and nasal specimen reveals Gram positive in cluster. What most likely mechanism is responsible for problem? a. Leithinase-mediated degeneration of tissue b. Excessive release of cytokines c. Toxin B-mediated disruption of the cytoskeleton d. Overreaction of cAMP 13 / 52 13) A 25-y woman came to ER having 5-hour of fever, rash, and altered mental status. Her BP is low (76/58) and HR is fast. After physical exam, a used tampon is removed from genital tract. Culture ofvaginal and nasal specimen reveals Gram positive in cluster. What factor is responsible for systemic shock syndrome? a. Panton-Valentine Leucocidin b. Superantigent (SAg)TSST-1 c. Exfoliative toxin d. Enterotoxin e. Protein A 14 / 52 14) A 6-year-old boy presents to his pediatrician for sore throat and a headache. His symptoms began approximately 2 days ago and have not improved. The boy appears uncomfortable and feels warm. Physical examination is notable for perioral crusted lesions with tonsillar swelling with exudates. Pharyngeal swap reveals gram positive cocci, with catalase negative and bacitracin sensitive. Which Lancefield group the pathogen belongs? a. Group F b. Group B c. Group D d. Group A 15 / 52 15) A 35-y patient was put on Central Venous Perfusion (CVP) line in an Intensive Care Unit (ICU) for 10 days. Culture grows staph epidermidis. What is appropriate description about staph epidermidis? a. Gram positive bacilli, catalase negative b. Gram positive cocci, DNAase negative c. Gram positive bacilli, coagulase positive d. Gram positive cocci, coagulase negative 16 / 52 16) Part of the success of the Streptococcus pyogenes bacterium lies in its ability to evade phagocytosis. Which of the following helps in this evasion? a. Streptolysin S b. Streptokinase c. M protein d. Pyrogenic toxin e. Streptolysin O 17 / 52 17) A 6-year-old boy presents to his pediatrician for sore throat and a headache. His symptoms began approximately 2 days ago and have not improved. The boy appears uncomfortable and feels warm. Physical examination is notable for perioral crusted lesions with tonsillar swelling with exudates. Pharyngeal swap reveals gram positive cocci, with catalase negative and bacitracin sensitive. Which of the following pathogens is causing the problem? a. Strep agalatiae b. Strep bovis c. Strep pyogenes d. Strep viridans 18 / 52 18) Which of the following bacteria is also called the gamma or nonhemolytic streptococci? a. Enterococcus b. Streptococcus pneumoniae c. Streptococcus spp. d. Streptococcus sanguinis 19 / 52 19) Within hours of food consumption, 45 year old man experienced acute gastroenteritis was admitted to the ICU. The patient progressed on to develop system shock. Culture of stool was positive for Staphylococcus aureus. What factor is responsible for acute gastroenteritis? a. Panton-Valentine Leukocidin b. Superantigent (SAg)TSST-1 c. Protein A d. Exfoliative toxin e. Enterotoxin 20 / 52 20) A 25-y woman came to ER having 5-hour of fever, rash, and altered mental status. Her BP is low (76/58) and HR is fast. Nasal specimen reveals Gramm positive in cluster with positive test for coagulase. What is most likely organism responsible for problem? a. Staph epidermidis b. Staph hominis c. Staph saprophyticus d. Staph aureus 21 / 52 21) Which test to be conducted to differentiate between Staph epidermidis and Staph saprophyticus? a. Gram stain b. Novobiocin test c. Catalase test d. Coagulase test 22 / 52 22) A 65-old man transferred to ER having sudden nausea vomiting & confusion. Physical exam: high fever 38.8C, Brudzinski positive and altered mental status. CSF Gramm stain reveals gramm+ lancet-shape diplococci. What pathogen is most likely pathogen responsible for the patient problem? a. Streptococcus pyogenes b. Streptococcus pneumoniae c. Streptococcus agalactiae d. Streptococcus intermedius 23 / 52 23) Which of the following cocci is found in the mouth as normal flora? a. Staphylococcus epidermidis b. Staphylococcus saprophyticus c. Streptococcus mutans d. Streptococcus agalactiae 24 / 52 24) The bacteria involved in the production of dental caries is a. Streptococcus pneumoniae b. Streptococcus mutans c. Streptococcus agalactiae d. Enterococcus 25 / 52 25) Which of bacteria having property of catalase positive, coagulase negative and Novobiocin sensitive? a. Staph epidermidis b. Staph aureus c. Staph lugdunensis d. Staph saprophyticus 26 / 52 26) A 19-y sexually active woman came to OPD having dysuria and pain when urinating. Urine culture reveals Gram positive, catalase positive cocci. Which two lab tests would be most helpful to distinguish the causal organism from other members? a. Catalase and urease b. Catalase and coagulase c. Catalase and hemolysis d. Coagulase and Novobiocin 27 / 52 27) A 6-year-old boy presents to his pediatrician for sore throat and a headache. His symptoms began approximately 2 days ago and have not improved. The boy appears uncomfortable and feels warm. Physical examination is notable for perioral crusted lesions with tonsillar swelling with exudates. Pharyngeal swap reveals Strep pyogenes as causal agent. Which of the following is true about the pathogen? a. Gram positive cocci, catalase negative and bacitracin resistant b. Gram positive cocci, catalase negative and bacitracin sensitive c. Gram positive cocci, catalase positive and bacitracin sensitive d. Gram positive cocci, catalase positive and bacitracin resistant 28 / 52 28) A 39-y patient is on Central Venous Perfusion line in an ICU. Culture around the line grows staph epidermidis. What is pathogenesis mechanism for this pathogen? a. Fibrinolectin F b. Protein A c. Protein M d. Biofilm 29 / 52 29) A 19-y sexually active woman came to OPD having dysuria and pain when urinating. Urine culture reveals staph saprophyticus. Which is urease test result for this pathogen? a. Normal b. Negative c. Non-normal d. Positive 30 / 52 30) 60-man is hospitalized for pneumonia and urine catheter is placed. Patient feels better after 2 days, however he has dysuria and urgency. A urine culture reveals gramm+ in pairs and chain. Antibiogram is resistant to vancomycin.What is most likely pathogen for this condition? a. Streptococcus spp. b. Streptococcus sanguinis c. Enterococcus d. Streptococcus pneumoniae 31 / 52 31) A 39-y patient is on Central Venous Perfusion line in an ICU. Culture around the line grows Gramm positive, Coagulase negative cocci in cluster. What the pathogen most likely reacts with Novobiocin test? a. Normal b. Sensitive c. Secretive d. Resistant 32 / 52 32) A 4-year boy was admitted establish the diagnosis of a generalized skin rash and fever. The family histories were not known because the boy was in care center from age of 2 months. The boy experienced frequent upper respiratory infections and tonsillitis. Diffused epidermal exfoliation from the face, thorax, members, and scalp were observed. What is most likely diagnosis for above condition? a. Acute gastroenteritis b. Staphylococcal Scalded Skin Syndrome c. Toxic shock syndrome d. Pneumoniae 33 / 52 33) A 17-year female was admitted complaining about a fever of 39.3oC and vomiting. She started her menstrual period 4 days before she became ill. Physical exam found most prominent erythematous rash on her trunk. Vaginal specimen shows catalase positive, Gram positive cocci. The patient was given intravenous fluids and IV antibiotics and transported to the hospital. Which of the following microorganism causes the condition? a. Streptococcus pneumonia b. Clostridium perfringens c. Staphylococcus aureus d. Streptococcus pyogenes 34 / 52 34) A 10-year-old male is taken to his physician by his parents due to a sore throat. The bacteria from throat specimen are gram-positive and bacitracin inhibits their growth. The child is given treatment of Penicillin G and sent home. Which of the following is most likely cause the problem? a. Strep agalatiae b. Strep pyogenes c. Strep viridans d. Strep bovis 35 / 52 35) A 10-year-old male is taken to his physician by his parents due to a sore throat. The bacteria from throat specimen are gram-positive and bacitracin inhibits their growth. The child is given treatment of Penicillin G and sent home. 20 years later, the patient presents to the emergency department with dyspnea on exertion and CXR showed an enlarged cardiac silhouette and pulmonary edema. The patient’s current symptomatology most likely occurred secondary to which of the following? a. Pyrogenic toxin superantigent b. Molecular mimicry of M protein c. Streptokinase invasion d. Streptolysin O antibodies 36 / 52 36) A 17-year female was admitted complaining about a fever of 39.3oC and vomiting. She started her menstrual period 4 days before she became ill. On the next day of admission, she had continued fever, vomiting and loose stools. She was hypotensive of SBP of 78 & DBP 54 mmHg with a heart rate of 120 beats per min. Physical exam found most prominent erythematous rash on her trunk. Cultures were obtained from vaginal specimen show catalase positive, Gram positive cocci of staphylococcus colonies. Which pathogen is responsible the stated problem? a. Clostridium perfringens b. Streptococcus pyogenes c. Staphylococcus aureus d. Streptococcus pneumonia 37 / 52 37) A 4-year boy was admitted establish the diagnosis of a generalized skin rash and fever. The family histories were not known because the boy was in care center from age of 2 months. The boy experienced frequent upper respiratory infections and tonsillitis. Diffused epidermal exfoliation from the face, thorax, members, and scalp were observed. What is most likely pathogen for above condition? a. Streptococcus agalactiae b. Staphylococcus aureus c. Streptococcus pyogens d. Staphylococcus saprophyticus 38 / 52 38) A 17-year female was admitted complaining about a fever of 39.3oC and vomiting. She started her menstrual period 4 days before she became ill. On the next day of admission, she had continued fever, vomiting and loose stools. She was hypotensive of SBP of 78 & DBP 54 mmHg with a heart rate of 120 beats per min. Physical exam found most prominent erythematous rash on her trunk. Cultures were obtained from vaginal specimen show catalase positive, Gram positive cocci. The patient was given intravenous fluids and IV antibiotics and transported to the hospital. Which pathogen causes the systemic syndrome? a. Streptococcus pyogenes b. Streptococcus pneumonia c. Staphylococcus aureus d. Clostridium perfringens 39 / 52 39) Which of the following bacteria have been found to be most resistant to the drug vancomycin? a. Enterococcus faecium b. Staphylococcus aureus c. Lactobacillus acidophilus d. Streptococcus pyogenes 40 / 52 40) A 17-year female was admitted complaining about a fever of 39.3oC and vomiting. She started her menstrual period 4 days before she became ill. On the next day of admission, she had continued fever, vomiting and loose stools. She was hypotensive of SBP of 78 & DBP 54 mmHg with a heart rate of 120 beats per min. Physical exam found most prominent erythematous rash on her trunk. Cultures were obtained from vaginal specimen show catalase positive, Gram positive cocci of staphylococcus colonies. Which action of the factors is explained for systemic shock syndrome? a. Panton-Valentine Leucocidin b. Enterotoxin c. Protein A d. Superantigent (SAg)TSST-1 e. Exfoliative toxin 41 / 52 41) A 4-year boy was admitted establish the diagnosis of a generalized skin rash and fever. The family histories were not known because the boy was in care center from age of 2 months. The boy experienced frequent upper respiratory infections and tonsillitis. Diffused epidermal exfoliation from the face, thorax, members, and scalp were observed. Culture of injured skin was positive for Staphylococcus aureus. What factor is responsible for the problem? a. Panton-Valentine Leukocidin b. Protein A c. Enterotoxin d. Superantigent (SAg)TSST-1 e. Exfoliative toxin 42 / 52 42) What pathogen causing indwelling device-associated infection? a. Staphylococcus epidemidis b. Enteroccocus c. Streptococcus pneumonia d. Streptococcus pyogenes 43 / 52 43) A 55-year-old man came to IPD complaining of weakness, malaise, and cough. He has history of smoking and social drinking. General condition upon admission was moderate: axillar temperature of 38 °C, respiratory rate of 21/min, SpO2 of 92%, heart rate at 90 beats/min, and blood pressure of 130/70 mm Hg. Bilateral pneumonia was suspected on chest-x ray. Culture of sputum showed coagulase positive, Gram positive cocci. What factor is responsible for the problem? a. Panton-Valentine Leukocidin (PVL) b. Protein A c. Exfoliative toxin d. Superantigent (SAg)TSST-1 e. Enterotoxin 44 / 52 44) A 14-year-old male is brought to the Emergency Department by his mother. She is worried because his face has become puffy and his urine has turned a tea-color. Patient history reveals the child recently suffered from a sore throat. The physician suspects a bacterial infection. Which of the following describes the likely bacterium responsible? a. Group A Alpha-hemolytic bacterium b. Group A Beta-hemolytic bacterium c. Group A Gama-hemolytic bacterium d. Group A non-hemolitic bacterium 45 / 52 45) What is the most common type of infection caused by Streptococcus pneumoniae? a. Otitis media b. Meningitis c. Sinusitis d. Pneumonia 46 / 52 46) Which biochemical test to distinguish between Staph epidermidis and Staph areus? a. Oxidase test b. Catalase test c. Motility test d. Coagulase test 47 / 52 47) A 17-year female was admitted complaining about a fever of 39.3oC and vomiting. She started her menstrual period 4 days before she became ill. Physical exam found most prominent erythematous rash on her trunk. Vaginal specimen revealed Staphylococcus aureus. The patient was given intravenous fluids and IV antibiotics and transported to the hospital. Which is true about the pathogen? a. Gram negative, catalase positive, coagulase negative b. Gram positive, catalase positive, coagulase positive c. Gram positive, catalase positive, coagulase negative d. Gram positive, catalase negative, coagulase negative 48 / 52 48) A 6-year-old boy presents to his pediatrician for sore throat and a headache. His symptoms began approximately 2 days ago and have not improved. The boy appears uncomfortable and feels warm. Physical examination is notable for perioral crusted lesions with tonsillar swelling with exudates. Pharyngeal swap reveals gram positive cocci, with catalase negative and bacitracin sensitive. Which group of hemolysis the pathogen belong? a. Gama hemolysis b. Beta hemolysis c. Alpha hemolysis d. Delta hemolysis 49 / 52 49) A 65-old man transferred to ER having sudden nausea vomiting & confusion. Physical exam: high fever 38.8C, Brudzinski positive and altered mental status. CSF Gramm stain reveals gramm+ lancet-shape diplococci. Which of the following is true about the pathogen? a. Group A and Optochin resistant b. Group A and Optochin sensitive c. Group B and Bacitracin sensitive d. Group B and Bacitracin resistant 50 / 52 50) A 6-year-old boy presents to his pediatrician for sore throat and a headache. His symptoms began approximately 2 days ago and have not improved. The boy appears uncomfortable and feels warm. Physical examination is notable for perioral crusted lesions with tonsillar swelling with exudates. Which of the following is most likely cause the problem? a. Strep bovis b. Strep agalatiae c. Strep pyogenes d. Strep viridans 51 / 52 51) What are property of Staph aureus ? a. coagulase negative, novobiocin positive b. coagulase negative, novobiocin resistant c. catalase positive, coagulase negative d. catalase positive, coagulase positive 52 / 52 52) A 6-year-old boy presents to his pediatrician for sore throat and a headache. His symptoms began approximately 2 days ago and have not improved. The boy appears uncomfortable and feels warm. Physical examination is notable for perioral crusted lesions with tonsillar swelling with exudates. Pharyngeal swap reveals gram positive cocci, with catalase negative and bacitracin sensitive. What is most likely diagnosis? a. Gonococcal pharyngitis b. Strep pharyngitis c. Meningococcal pharyngitis d. Staph pharyngitis Your score isThe average score is 89% Facebook 0% Restart quiz Any comments? Send feedback