/100
0

Oral Biology Preparation (Dr. Try Ky)

 

1 / 100

1)

Growth factors and their receptors can be grouped into β€˜families,’ based upon shared features of size and location, and into β€˜superfamilies,’ based upon shared their functions.?

2 / 100

2)

Non-marrow origin mesenchymal stem cells EXCLUDE ?

3 / 100

3)

A protein that binds to DNA and regulates gene expression by promoting or suppressing transcription?

4 / 100

4)

In our blood, there is a small amount of stem cells which are ready to be differentiate to any cell type under the control of growth factors.?

5 / 100

5)

Mesenchymal stem cells is derived from bone marrow. So they can differentiate into hematopoietic cell line.?

6 / 100

6)

What is the hierarchy of embryonic stem cells?

7 / 100

7)

Work flow of generating iPSc?

8 / 100

8)

How many protein structure were classified?

9 / 100

9)

The process by which information from a gene is used in the synthesis of a functional gene product such as a protein?

10 / 100

10)

Mesenchymal stem cells can be extracted from marrow and non-marrow.?

11 / 100

11)

Growth factor is sometimes used interchangeably among scientists with the term?

12 / 100

12)

iPSc were generated by:?

13 / 100

13)

Embryonic stem cells were banned for basic research practice because it is an unethical practice. Moreover, it cannot create patient-match specific cell line.?

14 / 100

14)

What are the gold standard transcription factors using for generating iPSc?

15 / 100

15)

ES will support clinical research on the differentiation and function of human tissues and provide material for testing that may improve the safety and efficacy of human drugs ?

16 / 100

16)

iPSc provided unlimited supplies of ________ cells could be used to generate transplants without the risk of immune rejection.?

17 / 100

17)

Event during or following protein translation ?

18 / 100

18)

Embryonic stem cells are derived from embryos at a developmental stage before the time that implantation would normally occur in the uterus. Normally, it takes about 10 days.?

19 / 100

19)

Activation, or promotion – increase the rate of gene transcription?

20 / 100

20)

The main reason for formation of scale is due to detraction of connective tissue.?

21 / 100

21)

When the first mouse iPSc were generated and published?

22 / 100

22)

When the first human iPSc were generated and published?

23 / 100

23)

Growth factor responsible for repair and regeneration: EGF, Epithermal growth factor?

24 / 100

24)

Cells responsible for repair and regeneration consist of?

25 / 100

25)

A protein that works with transcription factors to increase the rate of gene transcription?

26 / 100

26)

Mesenchymal stem cells can be extract from many types of tissue, but the most commence one is bone marrow.?

27 / 100

27)

What is the biggest conflict of using induced pluri-potent stem cells?

28 / 100

28)

The disadvantage of mesenchymal stem cells is that this stem cells are heterogenous in nature which hard to purify.?

29 / 100

29)

Why transcription factors is the most import key to generate iPSc, cell reprogramming?

30 / 100

30)

What is Yamanaka’s factors?

31 / 100

31)

Who are/ is the pioneer of generating iPSc?

32 / 100

32)

Controlling the rate of gene transcription for example by helping or hindering RNA polymerase binding to DNA?

33 / 100

33)

What is the hierarchy of mesenchymal stem cells?

34 / 100

34)

Yamanaka’s factors were used to generating iPSc in 1st generation because:?

35 / 100

35)

The biggest concern of using iPSc as a regenerative tool is the possible of cancer provoke due to infection of transcription factors.?

36 / 100

36)

A,growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation. Usually it is a protein or a steroid hormone.?

37 / 100

37)

Transcription factors sometime is called ?

38 / 100

38)

What is the biggest conflict of using mesenchymal stem cells?

39 / 100

39)

Upon introduction of reprogramming factors, cells begin to form colonies that resemble pluripotent stem cells, which can be isolated based on their:?

40 / 100

40)

Growth factors and their receptors can be grouped into β€˜families,’ based upon shared features of ?

41 / 100

41)

Ethical issues associated with the production of ESCs do apply to iPSCs, which offer a controversial strategy to generate patient-specific stem cell lines.?

42 / 100

42)

A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.?

43 / 100

43)

All four factors are absolutely necessary. In particular, the gene c-Myc is known to promote tumor growth in some cases, which would not affect iPSC usefulness in transplantation therapies. ?

44 / 100

44)

Growth factor responsible for repair and regeneration: VEGF, Vascular endothelial growth factor?

45 / 100

45)

If the ICM, inner cell mass, is removed from its normal embryonic environment and cultured under appropriate conditions, the ICM-derived cells can ——————————————- indefinitely and still maintain the developmental potential to form any cell type of the body?

46 / 100

46)

A protein that works with transcription factors to decrease the rate of gene transcription?

47 / 100

47)

Chromatin immunoprecipitation (ChIP) is a type of immunoprecipitation experimental technique used to investigate the interaction between?

48 / 100

48)

In the future, possible dentist can use dental pulp stem cells, 3rd mandibular molar, in cell bank due to their pluri-potent.?

49 / 100

49)

What do Growth Factors Do?

50 / 100

50)

Morphology of mesenchymal stem cells ?

51 / 100

51)

One strategy to accomplish this goal is nuclear reprogramming, a technique that involves experimentally inducing a stable change in the nucleus of a mature cell that can then be maintained and replicated as the cell divides through mitosis. ?

52 / 100

52)

iPSCs were reprogrammed to an embryonic stem cell-like state by introducing genes important for maintaining the essential properties of embryonic stem cells (ESCs). ?

53 / 100

53)

Why generation of iPSc is so attractive to scientist worldwide?

54 / 100

54)

Growth factor is sometimes used interchangeably among scientists with the term cytokine.?

55 / 100

55)

Protein synthesis consist of 2 steps. What are they, and where do they take place?

56 / 100

56)

Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, insertions, translocations and inversions at specific sites?

57 / 100

57)

Four transcription factors (Oct4, Sox2, Klf4, and c-Myc) sometimes is called Yamanaka’s factors.?

58 / 100

58)

The biggest different of outcome between repair and regeneration on tissue is tissue scaring.?

58)

 

59 / 100

59)

What are the criteria for achieving to generate iPSc?

60 / 100

60)

What is the outcome of regeneration?

61 / 100

61)

Growth factors typically act as signalling molecules between cells. Examples are cytokines and hormones that bind to specific receptors on the cytoplasm of their target cells.?

62 / 100

62)

Stem cell hierarchy from top to bottom?

63 / 100

63)

Transcription can be divided into 3 stages: initiation, elongation, and termination, each regulated by a large number of proteins such as transcription factors?

64 / 100

64)

Mesenchymal stem cells have been confirmed able to differentiated into neuron cell with function?

65 / 100

65)

Why transcription factor C-Myc is no longer use for generating iPSc?

66 / 100

66)

How many types of intra oral tissue?

67 / 100

67)

A specific sequence of DNA that a transcription factor binds to?

68 / 100

68)

Growth factors and their receptors can be grouped into β€˜superfamilies,’ based upon shared features of ?

69 / 100

69)

Retroviruses used to deliver the four transcription factors in the earliest studies is safe to generating iPSCs.?

70 / 100

70)

Why embryonic stem cells were banned for basic research?

71 / 100

71)

What is the outcome of repair?

72 / 100

72)

Growth factor is sometimes used interchangeably among scientists with the term transcription factors.?

73 / 100

73)

Some important human diseases are caused by the death or dysfunction of one or a few cell types, e.g., insulin-producing cells in diabetes or dopaminergic neurons in Parkinson’s disease. Therefore, understanding and using stem cells as tool to study this disease model provide a better understand this dysfunction of cell types.?

74 / 100

74)

Growth factor responsible for repair and regeneration: KGF, Keratinocyte growth factor?

75 / 100

75)

Growth factor responsible for repair and regeneration: PDGF, Platelet derived growth factor?

76 / 100

76)

Growth factor responsible for repair and regeneration: TGF-b, Transforming growth factor b.?

77 / 100

77)

Repression, or suppression – decrease the rate of gene transcription?

78 / 100

78)

Mesenchymal stem cells are multi-potent stem cells which is able to differentiate to adult cell like?

79 / 100

79)

What is the biggest conflict of using embryonic stem cells?

80 / 100

80)

An undifferentiated cell of a multicellular organism which is capable of giving rise to indefinitely more cells of the same type, and from which certain other kinds of cell arise by differentiation.?

81 / 100

81)

Growth factors are proteins that regulate many aspects of cellular function, including survival, proliferation, migration and differentiation.?

82 / 100

82)

The first differentiation event in humans occurs at approximately —— days of development, when an outer layer of cells committed to becoming part of the placenta (the trophectoderm) separates from the inner cell mass (ICM). ?

83 / 100

83)

Transcription factor sometimes is called sequence-specific DNA-binding factor.?

84 / 100

84)

What are the function of transcription factors?

85 / 100

85)

The process of making messenger RNA (mRNA) from a DNA template by RNA polymerase?

86 / 100

86)

Because ES cells can proliferate without limit and can contribute to any cell type, human ES cells offer an unprecedented access to tissues from the human body. ?

87 / 100

87)

Yamanaka’s factors were chosen because they were known to be involved in the maintenance of pluripotency, which is the capability to generate all other cell types of the body.?

88 / 100

88)

What is the hierarchy of induced pluripotent stem cells?

89 / 100

89)

Growth factor responsible for repair and regeneration: FGF, fibroblast growth factor.?

90 / 100

90)

What are the 4 steps of responses of mucosa to damage?

91 / 100

91)

The ICM, inner cell mass, cells have the potential to generate any cell type of the body, after implantation, they are ————– as they differentiate to other cell types with more limited developmental potential. ?

92 / 100

92)

Transcription factors is a protein that control the rate of transcription of genetic information from?

93 / 100

93)

Transcription factor is a protein that controls the rate of transcription of genetic information from messenger RNA to DNA, by binding to a specific ribosomes.?

94 / 100

94)

In transcription an mRNA chain is generated, with both strands of the DNA double helix in the genome as a template.?

95 / 100

95)

Embryonic stem cells are derived from embryos at a developmental stage before the time that implantation would normally occur in?

96 / 100

96)

Periodontium which includes?

97 / 100

97)

The inner cell mass cells have the potential to generate any cell type of the body, but after implantation, they are quickly depleted as they differentiate to other cell types with more limited developmental potential. ?

98 / 100

98)

In order to identify multi-potency stem cells, ones has to undergo cellar differentiation EXCLUDE?

99 / 100

99)

There are two major factors influence repair and regeneration?

100 / 100

100)

Cytokines are a broad and loose category of long big proteins (~5–20 kDa) that are important in cell signalling.?

Your score is

The average score is 0%

0%

Any comments?