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373

Oral Biology Preparation (Dr. Try Ky)

 

1 / 100

1)

Non-marrow origin mesenchymal stem cells EXCLUDE ?

2 / 100

2)

In the future, possible dentist can use dental pulp stem cells, 3rd mandibular molar, in cell bank due to their pluri-potent.?

3 / 100

3)

Upon introduction of reprogramming factors, cells begin to form colonies that resemble pluripotent stem cells, which can be isolated based on their:?

4 / 100

4)

Transcription factor sometimes is called sequence-specific DNA-binding factor.?

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5)

Growth factors are proteins that regulate many aspects of cellular function, including survival, proliferation, migration and differentiation.?

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6)

What is the outcome of regeneration?

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7)

Mesenchymal stem cells can be extract from many types of tissue, but the most commence one is bone marrow.?

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8)

Controlling the rate of gene transcription for example by helping or hindering RNA polymerase binding to DNA?

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9)

iPSc provided unlimited supplies of ________ cells could be used to generate transplants without the risk of immune rejection.?

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10)

The process by which information from a gene is used in the synthesis of a functional gene product such as a protein?

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11)

Periodontium which includes?

12 / 100

12)

What is the biggest conflict of using embryonic stem cells?

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13)

Morphology of mesenchymal stem cells ?

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14)

Ethical issues associated with the production of ESCs do apply to iPSCs, which offer a controversial strategy to generate patient-specific stem cell lines.?

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15)

Repression, or suppression – decrease the rate of gene transcription?

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16)

A specific sequence of DNA that a transcription factor binds to?

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17)

Why transcription factors is the most import key to generate iPSc, cell reprogramming?

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18)

A protein that works with transcription factors to decrease the rate of gene transcription?

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19)

The main reason for formation of scale is due to detraction of connective tissue.?

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20)

A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.?

21 / 100

21)

What is the hierarchy of induced pluripotent stem cells?

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22)

Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, insertions, translocations and inversions at specific sites?

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23)

How many types of intra oral tissue?

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24)

Who are/ is the pioneer of generating iPSc?

25 / 100

25)

What is the outcome of repair?

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26)

The biggest concern of using iPSc as a regenerative tool is the possible of cancer provoke due to infection of transcription factors.?

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27)

Retroviruses used to deliver the four transcription factors in the earliest studies is safe to generating iPSCs.?

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28)

What is the hierarchy of embryonic stem cells?

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29)

When the first human iPSc were generated and published?

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30)

Growth factor responsible for repair and regeneration: TGF-b, Transforming growth factor b.?

31 / 100

31)

Mesenchymal stem cells can be extracted from marrow and non-marrow.?

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32)

Growth factor is sometimes used interchangeably among scientists with the term transcription factors.?

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33)

Growth factor responsible for repair and regeneration: KGF, Keratinocyte growth factor?

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34)

Growth factors and their receptors can be grouped into β€˜families,’ based upon shared features of ?

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35)

Event during or following protein translation ?

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36)

How many protein structure were classified?

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37)

A,growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation. Usually it is a protein or a steroid hormone.?

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38)

Embryonic stem cells were banned for basic research practice because it is an unethical practice. Moreover, it cannot create patient-match specific cell line.?

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39)

An undifferentiated cell of a multicellular organism which is capable of giving rise to indefinitely more cells of the same type, and from which certain other kinds of cell arise by differentiation.?

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40)

There are two major factors influence repair and regeneration?

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41)

Yamanaka’s factors were chosen because they were known to be involved in the maintenance of pluripotency, which is the capability to generate all other cell types of the body.?

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42)

Chromatin immunoprecipitation (ChIP) is a type of immunoprecipitation experimental technique used to investigate the interaction between?

43 / 100

43)

The ICM, inner cell mass, cells have the potential to generate any cell type of the body, after implantation, they are ————– as they differentiate to other cell types with more limited developmental potential. ?

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44)

If the ICM, inner cell mass, is removed from its normal embryonic environment and cultured under appropriate conditions, the ICM-derived cells can ——————————————- indefinitely and still maintain the developmental potential to form any cell type of the body?

45 / 100

45)

Protein synthesis consist of 2 steps. What are they, and where do they take place?

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46)

What is the biggest conflict of using mesenchymal stem cells?

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47)

In order to identify multi-potency stem cells, ones has to undergo cellar differentiation EXCLUDE?

48 / 100

48)

In our blood, there is a small amount of stem cells which are ready to be differentiate to any cell type under the control of growth factors.?

49 / 100

49)

Work flow of generating iPSc?

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50)

Growth factors typically act as signalling molecules between cells. Examples are cytokines and hormones that bind to specific receptors on the cytoplasm of their target cells.?

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51)

What is the biggest conflict of using induced pluri-potent stem cells?

52 / 100

52)

Transcription can be divided into 3 stages: initiation, elongation, and termination, each regulated by a large number of proteins such as transcription factors?

53 / 100

53)

What is Yamanaka’s factors?

54 / 100

54)

One strategy to accomplish this goal is nuclear reprogramming, a technique that involves experimentally inducing a stable change in the nucleus of a mature cell that can then be maintained and replicated as the cell divides through mitosis. ?

55 / 100

55)

What are the criteria for achieving to generate iPSc?

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56)

The process of making messenger RNA (mRNA) from a DNA template by RNA polymerase?

57 / 100

57)

ES will support clinical research on the differentiation and function of human tissues and provide material for testing that may improve the safety and efficacy of human drugs ?

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58)

What is the hierarchy of mesenchymal stem cells?

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59)

Mesenchymal stem cells have been confirmed able to differentiated into neuron cell with function?

60 / 100

60)

Growth factor responsible for repair and regeneration: PDGF, Platelet derived growth factor?

61 / 100

61)

What are the 4 steps of responses of mucosa to damage?

62 / 100

62)

Four transcription factors (Oct4, Sox2, Klf4, and c-Myc) sometimes is called Yamanaka’s factors.?

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63)

Activation, or promotion – increase the rate of gene transcription?

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64)

Stem cell hierarchy from top to bottom?

65 / 100

65)

Cytokines are a broad and loose category of long big proteins (~5–20 kDa) that are important in cell signalling.?

66 / 100

66)

What are the function of transcription factors?

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67)

Growth factors and their receptors can be grouped into β€˜superfamilies,’ based upon shared features of ?

68 / 100

68)

Why transcription factor C-Myc is no longer use for generating iPSc?

69 / 100

69)

Growth factor is sometimes used interchangeably among scientists with the term?

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70)

Growth factors and their receptors can be grouped into β€˜families,’ based upon shared features of size and location, and into β€˜superfamilies,’ based upon shared their functions.?

71 / 100

71)

Why embryonic stem cells were banned for basic research?

72 / 100

72)

Transcription factor is a protein that controls the rate of transcription of genetic information from messenger RNA to DNA, by binding to a specific ribosomes.?

73 / 100

73)

Growth factor responsible for repair and regeneration: FGF, fibroblast growth factor.?

74 / 100

74)

iPSc were generated by:?

75 / 100

75)

Transcription factors is a protein that control the rate of transcription of genetic information from?

76 / 100

76)

The biggest different of outcome between repair and regeneration on tissue is tissue scaring.?

76)

 

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77)

Because ES cells can proliferate without limit and can contribute to any cell type, human ES cells offer an unprecedented access to tissues from the human body. ?

78 / 100

78)

Embryonic stem cells are derived from embryos at a developmental stage before the time that implantation would normally occur in?

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79)

Mesenchymal stem cells are multi-potent stem cells which is able to differentiate to adult cell like?

80 / 100

80)

What are the gold standard transcription factors using for generating iPSc?

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81)

The disadvantage of mesenchymal stem cells is that this stem cells are heterogenous in nature which hard to purify.?

82 / 100

82)

Mesenchymal stem cells is derived from bone marrow. So they can differentiate into hematopoietic cell line.?

83 / 100

83)

A protein that works with transcription factors to increase the rate of gene transcription?

84 / 100

84)

Growth factor is sometimes used interchangeably among scientists with the term cytokine.?

85 / 100

85)

Embryonic stem cells are derived from embryos at a developmental stage before the time that implantation would normally occur in the uterus. Normally, it takes about 10 days.?

86 / 100

86)

Transcription factors sometime is called ?

87 / 100

87)

Yamanaka’s factors were used to generating iPSc in 1st generation because:?

88 / 100

88)

In transcription an mRNA chain is generated, with both strands of the DNA double helix in the genome as a template.?

89 / 100

89)

What do Growth Factors Do?

90 / 100

90)

Why generation of iPSc is so attractive to scientist worldwide?

91 / 100

91)

The inner cell mass cells have the potential to generate any cell type of the body, but after implantation, they are quickly depleted as they differentiate to other cell types with more limited developmental potential. ?

92 / 100

92)

All four factors are absolutely necessary. In particular, the gene c-Myc is known to promote tumor growth in some cases, which would not affect iPSC usefulness in transplantation therapies. ?

93 / 100

93)

Growth factor responsible for repair and regeneration: EGF, Epithermal growth factor?

94 / 100

94)

When the first mouse iPSc were generated and published?

95 / 100

95)

Cells responsible for repair and regeneration consist of?

96 / 100

96)

iPSCs were reprogrammed to an embryonic stem cell-like state by introducing genes important for maintaining the essential properties of embryonic stem cells (ESCs). ?

97 / 100

97)

Growth factor responsible for repair and regeneration: VEGF, Vascular endothelial growth factor?

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98)

Some important human diseases are caused by the death or dysfunction of one or a few cell types, e.g., insulin-producing cells in diabetes or dopaminergic neurons in Parkinson’s disease. Therefore, understanding and using stem cells as tool to study this disease model provide a better understand this dysfunction of cell types.?

99 / 100

99)

A protein that binds to DNA and regulates gene expression by promoting or suppressing transcription?

100 / 100

100)

The first differentiation event in humans occurs at approximately —— days of development, when an outer layer of cells committed to becoming part of the placenta (the trophectoderm) separates from the inner cell mass (ICM). ?

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